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  1. Article ; Online: Dietary and Physiological Factors Affecting Lipid Metabolism and Cardiovascular Risk.

    Yoshida, Hiroshi

    Journal of nutritional science and vitaminology

    2022  Volume 68, Issue Supplement, Page(s) S119–S120

    Abstract: Atherosclerotic cardiovascular disease (ASCVD) is one of the leading causes of death worldwide. The risk of developing CVD is associated with an unhealthy lifestyle. A high level of low-density lipoprotein (LDL) cholesterol (LDL-C) is a primary risk ... ...

    Abstract Atherosclerotic cardiovascular disease (ASCVD) is one of the leading causes of death worldwide. The risk of developing CVD is associated with an unhealthy lifestyle. A high level of low-density lipoprotein (LDL) cholesterol (LDL-C) is a primary risk factor for ASCVD. However, even if the LDL-C management target has been achieved, hypertriglyceridemia and a high level of total cholesterol minus high-density lipoprotein (HDL) cholesterol (non-HDL-C), which contains cholesterol concentrations of triglyceride-rich lipoproteins, are considered a significant residual risk factor for ASCVD and consequently the management of these conditions is important for controlling the residual risk for ASCVD.
    MeSH term(s) Humans ; Cardiovascular Diseases/etiology ; Lipid Metabolism ; Cholesterol, LDL ; Risk Factors ; Heart Disease Risk Factors ; Cholesterol, HDL ; Atherosclerosis/etiology ; Cholesterol
    Chemical Substances Cholesterol, LDL ; Cholesterol, HDL ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2022-09-23
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 191366-9
    ISSN 1881-7742 ; 0301-4800
    ISSN (online) 1881-7742
    ISSN 0301-4800
    DOI 10.3177/jnsv.68.S119
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Is the Japan Diet Instrumental in Preventing Cardiovascular Diseases?

    Yoshida, Hiroshi

    Journal of atherosclerosis and thrombosis

    2021  Volume 28, Issue 10, Page(s) 1023–1024

    MeSH term(s) Cardiovascular Diseases/blood ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Diet ; Diet, Healthy ; Diet, Mediterranean ; Heart Disease Risk Factors ; Humans ; Japan/epidemiology ; Life Style ; Protective Factors
    Language English
    Publishing date 2021-05-29
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2011474-6
    ISSN 1880-3873 ; 1340-3478
    ISSN (online) 1880-3873
    ISSN 1340-3478
    DOI 10.5551/jat.ED175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: To be Functional, or not to be Low in Cholesterol, that is the Clinical Concern when Evaluating Anti-Atherosclerotic Actions of High-Density Lipoproteins.

    Yoshida, Hiroshi

    Journal of atherosclerosis and thrombosis

    2021  Volume 28, Issue 7, Page(s) 694–695

    MeSH term(s) Apolipoprotein A-I/metabolism ; Atherosclerosis/metabolism ; Coronary Disease/blood ; Coronary Disease/metabolism ; Heart Disease Risk Factors ; Humans ; Inflammation/metabolism ; Lipoproteins, HDL/blood ; Lipoproteins, HDL/metabolism ; Oxidation-Reduction ; Protective Factors ; Transcytosis/physiology
    Chemical Substances Apolipoprotein A-I ; Lipoproteins, HDL
    Language English
    Publishing date 2021-05-22
    Publishing country Japan
    Document type Editorial
    ZDB-ID 2011474-6
    ISSN 1880-3873 ; 1340-3478
    ISSN (online) 1880-3873
    ISSN 1340-3478
    DOI 10.5551/jat.ED173
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  4. Article: [Surgery and IVR for the treatment of portal hypertension].

    Yoshida, Hiroshi

    Nihon Shokakibyo Gakkai zasshi The Japanese journal of gastro-enterology

    2019  Volume 116, Issue 5, Page(s) 404–411

    MeSH term(s) Humans ; Hypertension, Portal/radiotherapy ; Hypertension, Portal/surgery ; Radiology, Interventional
    Language Japanese
    Publishing date 2019-04-29
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 708695-7
    ISSN 1349-7693 ; 0446-6586
    ISSN (online) 1349-7693
    ISSN 0446-6586
    DOI 10.11405/nisshoshi.116.404
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Lipoprotein Analysis -Measurement of Lipoprotein Fractions and Anion-Exchange High-Performance Liquid Chromatography].

    Yoshida, Hiroshi

    Rinsho byori. The Japanese journal of clinical pathology

    2019  Volume 64, Issue 6, Page(s) 643–650

    Abstract: Many clinical studies, including Framingham Heart study, have demonstrated that increased LDL choles- terol and decreased HDL cholesterol are associated with the risk of coronary heart disease (CHD), and lipo- protein evaluation is of importance in the ... ...

    Abstract Many clinical studies, including Framingham Heart study, have demonstrated that increased LDL choles- terol and decreased HDL cholesterol are associated with the risk of coronary heart disease (CHD), and lipo- protein evaluation is of importance in the prevention and treatment of CHD risk. Lipoprotein analysis methods by high performance liquid chromatography (HPLC) are divided broadly into 2 categories (HPLC with gel-filtration column and with anion-exchange column), and both methods can determine lipid levels of fractionated serum lipoproteins in a small volume of around 10 pL within 30 min. In contrast, with the gel- filtration HPLC method by Gaussian approximation following the particle sizes, the anion-exchange HPLC method elutes lipoproteins following the ion intensity of the lipoprotein particle surface and the hydrophobic property, and determines cholesterol levels of separated lipoproteins without overlapping lipoprotein frac- tions. We have established a method with anion-exchange chromatography using a 1.0-mL injection volume that 5.2 min takes to assay one sample. The within-day and between-day assay coefficients of variation of lipoprotein cholesterol values were 0.33-4.31 and 2.37-9.19%, respectively. Previous studies generating fractionated lipoprotein cholesterol data using anion-exchange HPLC revealed the clinical significance in a variety of settings and, in Japan, this rapid anion-exchange HPLC assay was approved as a medical examina- tion covered by health insurance for medical service fees in 2013, and the anion-exchange HPLC method for lipoprotein fraction cholesterol measurement has the potential to offer further clinical benefit. [Review].
    MeSH term(s) Chromatography, Gel ; Chromatography, High Pressure Liquid ; Chromatography, Ion Exchange/instrumentation ; Chromatography, Ion Exchange/methods ; Humans ; Lipoproteins/blood
    Chemical Substances Lipoproteins
    Language Japanese
    Publishing date 2019-01-29
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 604196-6
    ISSN 0047-1860 ; 0485-1404
    ISSN 0047-1860 ; 0485-1404
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Outline of Metabolism and Nutrition Section in Clinical Laboratory Examination Guideline JSLM2015].

    Yoshida, Hiroshi

    Rinsho byori. The Japanese journal of clinical pathology

    2019  Volume 65, Issue 3, Page(s) 309–313

    Abstract: The metabolism and nutrition section of JSLM2015 was constructed following the previous version JSLM2012. The examinations of dyslipidemia and glucose metabolism and weight loss and obesity were described in the first chapter Laboratory data approach and ...

    Abstract The metabolism and nutrition section of JSLM2015 was constructed following the previous version JSLM2012. The examinations of dyslipidemia and glucose metabolism and weight loss and obesity were described in the first chapter Laboratory data approach and the second chapter Symptoms, respectively. Dyslipidemia, diabetes, gout and hyperuricemia, and osteoporosis were described in the third chapter Diseas- es. This paper provides an outline with a focus on dyslipidemia examination and dyslipidemia in the first and third chapters, respectively. [Review].
    MeSH term(s) Clinical Laboratory Services ; Diabetes Mellitus ; Dyslipidemias ; Gout ; Hypertension ; Nutritional Sciences/education ; Obesity
    Language Japanese
    Publishing date 2019-02-24
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 604196-6
    ISSN 0047-1860 ; 0485-1404
    ISSN 0047-1860 ; 0485-1404
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Surgical Treatment for Locally Advanced Adenoid Cystic Carcinoma of the Bartholin's Gland: A Case Report.

    Yoshida, Hiroshi

    The Tokai journal of experimental and clinical medicine

    2019  Volume 44, Issue 4, Page(s) 68–72

    Abstract: Adenoid cystic carcinoma (ACC) of the Bartholin's gland (BACC) is an extremely rare malignancy of the vulva. The characteristics of BACC include slow tumor growth and aggressive invasion, especially with perineural involvement. A 64-year-old Japanese ... ...

    Abstract Adenoid cystic carcinoma (ACC) of the Bartholin's gland (BACC) is an extremely rare malignancy of the vulva. The characteristics of BACC include slow tumor growth and aggressive invasion, especially with perineural involvement. A 64-year-old Japanese woman complained of a mass and pain in the perineum. A 3 cm-sized mass was palpated inside of the labia majora. Diagnostic imaging demonstrated the tumor invading the anus and urethra. The patient underwent total pelvic exenteration with radical vulvectomy. Pathological findings revealed that the tumor was BACC. The surgical margin was positive for tumor cells, which necessitated adjuvant radiotherapy. No serious complications were associated with the surgery and radiotherapy. There is no clear consensus on to the proper surgical intervention in BACC. Achieving tumor-free surgical margins is desired to avoid recurrence. However, such attempts have often failed in reported BACC cases with extended surgical resection. Nevertheless, given the aggressive nature of BACC, extensive surgery including total pelvic exenteration is justified, particularly with promising reported efficacy of adjuvant radiotherapy on BACC prognosis.
    MeSH term(s) Bartholin's Glands/diagnostic imaging ; Bartholin's Glands/pathology ; Bartholin's Glands/surgery ; Carcinoma, Adenoid Cystic/diagnostic imaging ; Carcinoma, Adenoid Cystic/pathology ; Carcinoma, Adenoid Cystic/surgery ; Female ; Humans ; Magnetic Resonance Imaging ; Margins of Excision ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Staging ; Radiotherapy, Adjuvant ; Treatment Outcome ; Vulvar Neoplasms/diagnostic imaging ; Vulvar Neoplasms/pathology ; Vulvar Neoplasms/surgery
    Language English
    Publishing date 2019-12-20
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 431622-8
    ISSN 2185-2243 ; 0385-0005
    ISSN (online) 2185-2243
    ISSN 0385-0005
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  8. Article ; Online: Clinical Impact and Significance of Serum Lipoprotein (a) Levels on Cardiovascular Risk in Patients With Coronary Artery Disease.

    Yoshida, Hiroshi

    Circulation journal : official journal of the Japanese Circulation Society

    2019  Volume 83, Issue 5, Page(s) 967–968

    MeSH term(s) Cardiovascular Diseases ; Coronary Angiography ; Coronary Artery Disease ; Humans ; Lipoprotein(a) ; Risk Factors
    Chemical Substances Lipoprotein(a)
    Language English
    Publishing date 2019-04-04
    Publishing country Japan
    Document type Editorial ; Comment
    ZDB-ID 2068090-9
    ISSN 1347-4820 ; 1346-9843
    ISSN (online) 1347-4820
    ISSN 1346-9843
    DOI 10.1253/circj.CJ-19-0221
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  9. Article: [Update on surgical treatment of colorectal cancer -latest preoperative treatment and the subsequent non-operative management].

    Uehara, Kay / Yamada, Takeshi / Yoshida, Hiroshi

    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology

    2024  Volume 121, Issue 3, Page(s) 197–203

    MeSH term(s) Humans ; Colorectal Neoplasms/surgery ; Retrospective Studies ; Preoperative Care
    Language Japanese
    Publishing date 2024-02-08
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 708695-7
    ISSN 1349-7693 ; 0446-6586
    ISSN (online) 1349-7693
    ISSN 0446-6586
    DOI 10.11405/nisshoshi.121.197
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  10. Article ; Online: An Intriguing and Important Concept Relevant to Oxidized Low-Density Lipoprotein and Atherogenesis is Still Problematic for its Contribution to the Better Understanding of Clinical Atherosclerosis.

    Yoshida, Hiroshi

    Journal of atherosclerosis and thrombosis

    2018  Volume 25, Issue 10, Page(s) 1007–1008

    MeSH term(s) Atherosclerosis/physiopathology ; Humans ; Lipoproteins, LDL/metabolism ; Prognosis
    Chemical Substances Lipoproteins, LDL ; oxidized low density lipoprotein
    Language English
    Publishing date 2018-08-02
    Publishing country Japan
    Document type Editorial
    ZDB-ID 2011474-6
    ISSN 1880-3873 ; 1340-3478
    ISSN (online) 1880-3873
    ISSN 1340-3478
    DOI 10.5551/jat.ED101
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