LIVIVO - Search results -

Search results

Result 1 - 10 of total 1911

Search options

Book ; Online: Optimal harvesting policy for biological resources with uncertain heterogeneity for application in fisheries management

Yoshioka, Hidekazu

2023

Abstract: Conventional harvesting problems for natural resources often assume physiological homogeneity of the body length/weight among individuals. However, such assumptions generally are not valid in real-world problems, where heterogeneity plays an essential ... ...

Abstract	Conventional harvesting problems for natural resources often assume physiological homogeneity of the body length/weight among individuals. However, such assumptions generally are not valid in real-world problems, where heterogeneity plays an essential role in the planning of biological resource harvesting. Furthermore, it is difficult to observe heterogeneity directly from the available data. This paper presents a novel optimal control framework for the cost-efficient harvesting of biological resources for application in fisheries management. The heterogeneity is incorporated into the resource dynamics, which is the population dynamics in this case, through a probability density that can be distorted from the reality. Subsequently, the distortion, which is the model uncertainty, is penalized through a divergence, leading to a non-standard dynamic differential game wherein the Hamilton-Jacobi-Bellman-Isaacs (HJBI) equation has a unique nonlinear partial differential term. Here, the existence and uniqueness results of the HJBI equation are presented along with an explicit monotone finite difference method. Finally, the proposed optimal control is applied to a harvesting problem with recreationally, economically, and ecologically important fish species using collected field data. Comment: Under second review in some journal
Keywords	Mathematics - Optimization and Control ; Computer Science - Computational Engineering ; Finance ; and Science
Subject code	531
Publishing date	2023-05-15
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Histiocytic sarcoma of the palate: a case report.

Kurimoto, T / Goto, T / Yasuda, T / Yoshioka, H

International journal of oral and maxillofacial surgery

2023 Volume 52, Issue 12, Page(s) 1225–1229

Abstract: Histiocytic sarcoma is a malignant proliferation of cells that exhibit morphological and immunophenotypic features of mature histiocytes. Owing to its rarity, its clinical features and standard treatment have not yet been established. This report ... ...

Abstract	Histiocytic sarcoma is a malignant proliferation of cells that exhibit morphological and immunophenotypic features of mature histiocytes. Owing to its rarity, its clinical features and standard treatment have not yet been established. This report describes a case of histiocytic sarcoma of the palate that developed in a 76-year-old man, the first report of an intraoral histiocytic sarcoma. An extended resection was performed; however, establishing the excision line was extremely difficult because assessing the tumour boundary on imaging was challenging and the tumour underwent dynamic gross morphological changes following biopsy. Complete resection is required to obtain a favourable prognosis for high-grade tumours with indistinct borders. In this case, an intraoperative rapid examination with frozen section analysis was performed along the planned excision line to completely resect the tumours exhibiting such behaviour. At 28 months postoperatively, the patient demonstrated no recurrence or metastasis; however, he is under careful monitoring.
MeSH term(s)	Male ; Humans ; Aged ; Histiocytic Sarcoma/diagnostic imaging ; Histiocytic Sarcoma/surgery ; Histiocytes/pathology ; Diagnostic Imaging ; Biopsy ; Palate
Language	English
Publishing date	2023-08-27
Publishing country	Denmark
Document type	Case Reports
ZDB-ID	353721-3
ISSN	1399-0020 ; 0901-5027
ISSN (online)	1399-0020
ISSN	0901-5027
DOI	10.1016/j.ijom.2023.08.003
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 931: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 401: Show issues

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾

Article ; Online: Two-species competing population dynamics with the population-dependent environmental capacities under random disturbance.

Yoshioka, Hidekazu

Theory in biosciences = Theorie in den Biowissenschaften

2020 Volume 139, Issue 3, Page(s) 279–297

Abstract: We propose and analyze a stochastic competing two-species population dynamics model subject to jump and continuous correlated noises. Competing benthic algae population dynamics in river environment, which is an important engineering problem, motivates ... ...

Abstract	We propose and analyze a stochastic competing two-species population dynamics model subject to jump and continuous correlated noises. Competing benthic algae population dynamics in river environment, which is an important engineering problem, motivates this new model. The model is a system of stochastic differential equations having a characteristic that the two populations are competing with each other through the environmental capacities; an increase in one population decreases the other's environmental capacity. Unique existence of the uniformly bounded strong solution is proven, and attractors of the solutions are identified depending on the parameter values. The Kolmogorov's backward equation associated with the population dynamics is formulated and its unique solvability in a Banach space with a weighted norm is discussed. A novel uncertain correlation case is also analyzed in the framework of viscosity solutions. Numerical computation results using a finite difference scheme and a Monte-Carlo method are presented to deeper analyze the model. Our analysis results can be utilized for establishment of a foundation for modeling, analysis and control of the competing population dynamics.
MeSH term(s)	Algorithms ; Animals ; Chlorophyta/physiology ; Computer Simulation ; Ecosystem ; Fisheries ; Fishes/microbiology ; Linear Models ; Models, Biological ; Models, Theoretical ; Monte Carlo Method ; Population Dynamics ; Stochastic Processes ; Viscosity
Language	English
Publishing date	2020-08-11
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1376847-5
ISSN	1611-7530 ; 1431-7613
ISSN (online)	1611-7530
ISSN	1431-7613
DOI	10.1007/s12064-020-00321-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 46/348: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: NADPH oxidase-mediated sulfenylation of cysteine derivatives is key regulatory events for plant immune responses.

Hino, Yuta / Inada, Taichi / Yoshioka, Miki / Yoshioka, Hirofumi

Journal of experimental botany

2024

Abstract: Reactive oxygen species (ROS) are rapidly generated during plant immune responses by RBOH, which is a plasma membrane-localizing NADPH oxidase. Although regulatory mechanisms of RBOH activity have been well documented, the ROS-mediated downstream ... ...

Abstract	Reactive oxygen species (ROS) are rapidly generated during plant immune responses by RBOH, which is a plasma membrane-localizing NADPH oxidase. Although regulatory mechanisms of RBOH activity have been well documented, the ROS-mediated downstream signaling is unclear. We here demonstrated that ROS sensor proteins play a central role in the ROS signaling via oxidative post-translational modification of cysteine residues, sulfenylation. To detect protein sulfenylation, we used dimedone, which specifically and irreversibly binds to sulfenylated proteins. The sulfenylated proteins were labeled by dimedone in Nicotiana benthamiana leaves, and the conjugates were detected by immunoblot analyses. In addition, a reductant dissociated H2O2-induced conjugates, suggesting that cysteine persulfide and/or polysulfides are involved in sulfenylation. These sulfenylated proteins were continuously increased during both PTI and ETI in a RBOH-dependent manner. Pharmacological inhibition of ROS sensor proteins by dimedone perturbated cell death, ROS accumulation induced by INF1 and MEK2DD, and defense against fungal pathogens. On the other hand, Rpi-blb2-mediated ETI responses were rather enhanced by dimedone. These results suggest that the sulfenylation of cysteine and its derivatives in various ROS sensor proteins are important events in downstream of RBOH-dependent ROS burst to regulate plant immune responses.
Language	English
Publishing date	2024-04-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2976-2
ISSN	1460-2431 ; 0022-0957
ISSN (online)	1460-2431
ISSN	0022-0957
DOI	10.1093/jxb/erae111
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 55/29: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A simplified stochastic optimization model for logistic dynamics with control-dependent carrying capacity.

Yoshioka, Hidekazu

Journal of biological dynamics

2019 Volume 13, Issue 1, Page(s) 148–176

Abstract: A simplified stochastic control model for optimization of logistic dynamics with the control-dependent carrying capacity, which is motivated by a recent algae population management problem in the river environment, is presented. Solving the optimization ... ...

Abstract	A simplified stochastic control model for optimization of logistic dynamics with the control-dependent carrying capacity, which is motivated by a recent algae population management problem in the river environment, is presented. Solving the optimization problem reduces to finding a solution to a non-local first-order differential equation called tt-Jacobi-Bellman (HJB) equation. It is shown that the HJB equation has a unique viscosity solution and that the solution can be approximated with a finite difference scheme. Asymptotic estimates of the solution and the optimal control are derived and compared with numerical solutions. Finally, parameter dependence of the optimal control is examined numerically with implications to river environmental management.
MeSH term(s)	Conservation of Natural Resources ; Models, Biological ; Numerical Analysis, Computer-Assisted ; Population Dynamics ; Stochastic Processes
Language	English
Publishing date	2019-02-06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1751-3766
ISSN (online)	1751-3766
DOI	10.1080/17513758.2019.1576927
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Data-driven disease progression model of Parkinson's disease and effect of sex and genetic variants.

Jin, Ryota / Yoshioka, Hideki / Sato, Hiromi / Hisaka, Akihiro

CPT: pharmacometrics & systems pharmacology

2024 Volume 13, Issue 4, Page(s) 649–659

Abstract: As Parkinson's disease (PD) progresses, there are multiple biomarker changes, and sex and genetic variants may influence the rate of progression. Data-driven, long-term disease progression model analysis may provide precise knowledge of the relationships ...

Abstract	As Parkinson's disease (PD) progresses, there are multiple biomarker changes, and sex and genetic variants may influence the rate of progression. Data-driven, long-term disease progression model analysis may provide precise knowledge of the relationships between these risk factors and progression and would allow for the selection of appropriate diagnosis and treatment according to disease progression. To construct a long-term disease progression model of PD based on multiple biomarkers and evaluate the effects of sex and leucine-rich repeat kinase 2 (LRRK2) mutations, a technique derived from the nonlinear mixed-effects model (Statistical Restoration of Fragmented Time course [SReFT]) was applied to datasets of patients provided by the Parkinson's Progression Markers Initiative. Four biomarkers, including the Unified PD Rating Scale, were used, and a covariate analysis was performed to investigate the effects of sex and LRRK2-related mutations. A model of disease progression over ~30 years was successfully developed using patient data with a median of 6 years. Covariate analysis suggested that female sex and LRRK2 G2019S mutations were associated with 21.6% and 25.4% significantly slower progression, respectively. LRRK2 rs76904798 mutation also tended to delay disease progression by 10.4% but the difference was not significant. In conclusion, a long-term PD progression model was successfully constructed using SReFT from relatively short-term individual patient observations and depicted nonlinear changes in relevant biomarkers and their covariates, including sex and genetic variants.
MeSH term(s)	Humans ; Female ; Parkinson Disease/genetics ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/genetics ; Mutation ; Biomarkers ; Disease Progression
Chemical Substances	Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 (EC 2.7.11.1) ; Biomarkers
Language	English
Publishing date	2024-02-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	2697010-7
ISSN	2163-8306 ; 2163-8306
ISSN (online)	2163-8306
ISSN	2163-8306
DOI	10.1002/psp4.13112
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: A stochastic differential game approach toward animal migration.

Yoshioka, Hidekazu

Theory in biosciences = Theorie in den Biowissenschaften

2019 Volume 138, Issue 2, Page(s) 277–303

Abstract: A stochastic differential game model for animal migration between two habitats under uncertain environment, a new population dynamics model, is formulated. Its novelty is the use of an impulse control formalism to naturally describe migrations with ... ...

Abstract	A stochastic differential game model for animal migration between two habitats under uncertain environment, a new population dynamics model, is formulated. Its novelty is the use of an impulse control formalism to naturally describe migrations with different timings and magnitudes that the conventional models could not handle. Uncertainty of the environment that the population faces with is formulated in the context of the multiplier robust control. The optimal migration strategy to give the maximized minimal profit is found through a Hamilton-Jacobi-Bellman quasi-variational inequality (HJBQVI). A key message from HJBQVI is that its free boundary determines the optimal migration strategy. Solving the HJBQVI is carried out with a specialized stable and convergent finite difference scheme. This paper theoretically suggests that the sub-additivity of the performance index, the index to be optimized through the migration, critically affects the resulting strategy. The computational results with the established scheme are consistent with the theoretical predictions and support importance of the sub-additivity property. Social interaction to reduce the net mortality rate is also quantified, suggesting a linkage between the present and existing population dynamics models.
MeSH term(s)	Algorithms ; Animal Migration ; Animals ; Computer Simulation ; Ecosystem ; Game Theory ; Interpersonal Relations ; Models, Theoretical ; Population Dynamics ; Stochastic Processes ; Time Factors
Language	English
Publishing date	2019-04-11
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1376847-5
ISSN	1611-7530 ; 1431-7613
ISSN (online)	1611-7530
ISSN	1431-7613
DOI	10.1007/s12064-019-00292-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 46/348: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Disease progression modeling with temporal realignment: An emerging approach to deepen knowledge on chronic diseases.

Yoshioka, Hideki / Jin, Ryota / Hisaka, Akihiro / Suzuki, Hiroshi

Pharmacology & therapeutics

2024 Volume 259, Page(s) 108655

Abstract: The recent development of the first disease-modifying drug for Alzheimer's disease represents a major advancement in dementia treatment. Behind this breakthrough is a quarter century of research efforts to understand the disease not by a particular ... ...

Abstract	The recent development of the first disease-modifying drug for Alzheimer's disease represents a major advancement in dementia treatment. Behind this breakthrough is a quarter century of research efforts to understand the disease not by a particular symptom at a given moment, but by long-term sequential changes in multiple biomarkers. Disease progression modeling with temporal realignment (DPM-TR) is an emerging computational approach proposed with this biomarker-based disease concept. By integrating short-term clinical observations of multiple disease biomarkers in a data-driven manner, DPM-TR provides a way to understand the progression of chronic diseases over decades and predict individual disease stages more accurately. DPM-TR has been developed primarily in the area of neurodegenerative diseases but has recently been extended to non-neurodegenerative diseases, including chronic obstructive pulmonary, autoimmune, and ophthalmologic diseases. This review focuses on opportunities for DPM-TR in clinical practice and drug development and discusses its current status and challenges.
Language	English
Publishing date	2024-05-04
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	194735-7
ISSN	1879-016X ; 0163-7258
ISSN (online)	1879-016X
ISSN	0163-7258
DOI	10.1016/j.pharmthera.2024.108655
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1183: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Book ; Online: River environmental restoration based on random observations of a non-smooth stochastic dynamical system

Yoshioka, Hidekazu

2020

Abstract: Earth and soils are indispensable elements of river environment. Dam-downstream environment and ecosystems have been severely affected by reduced or even stopped sediment supply from the upstream. Replenishing earth and soils from outside the river has ... ...

Abstract	Earth and soils are indispensable elements of river environment. Dam-downstream environment and ecosystems have been severely affected by reduced or even stopped sediment supply from the upstream. Replenishing earth and soils from outside the river has been considered as an effective way to mitigate this issue. However, its cost-effective implementation has not been considered from a theoretical side. This paper presents a tractable new stochastic control model to deal with this issue. The sediment dynamics in the river environment follow non-smooth and continuous-time piecewise deterministic dynamics. The model assumes that the observation of the sediment dynamics is carried out only randomly and discretely, and that the sediment can be replenished at each observation time with cost. This partial observation assumption is consistent with the fact that continuously obtaining the environmental information is difficult in applications. The performance index to penalize the sediment depletion has a non-smooth term as well. We demonstrate that these non-smoothness factors harmonize with a dynamic programming principle, and derive the optimality equation in a degenerate elliptic form governing the most cost-efficient sediment replenishment policy. We analytically derive and verify an exact solution under a simplified condition for a discounted case, an Ergodic case, and a complete information case. A more realistic case is handled using a high-resolution finite difference scheme. We then provide the optimal sediment replenishment policy numerically.
Keywords	Electrical Engineering and Systems Science - Systems and Control ; Mathematics - Optimization and Control
Subject code	333
Publishing date	2020-05-10
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Book ; Online: Mathematical and computational approaches for stochastic control of river environment and ecology

Yoshioka, Hidekazu

from fisheries viewpoint

2020

Abstract: We present a modern stochastic control framework for dynamic optimization of river environment and ecology. We focus on a fisheries problem in Japan, and show several examples of simplified optimal control problems of stochastic differential equations ... ...

Abstract	We present a modern stochastic control framework for dynamic optimization of river environment and ecology. We focus on a fisheries problem in Japan, and show several examples of simplified optimal control problems of stochastic differential equations modeling fishery resource dynamics, reservoir water balance dynamics, benthic algae dynamics, and sediment storage dynamics. These problems concern different phenomena with each other, but they all reduce to solving degenerate parabolic or elliptic equations. Optimal controls and value functions of these problems are computed using finite difference schemes. Finally, we present a higher-dimensional problem of controlling a dam-reservoir system using a semi-Lagrangian discretization on sparse grids. Our contribution shows the state-of-art of modeling, analysis, and computation of stochastic control in environmental engineering and science, and related research areas. Comment: Accepted as a chapter to a book series
Keywords	Mathematics - Optimization and Control ; Electrical Engineering and Systems Science - Systems and Control ; Mathematics - Numerical Analysis
Subject code	510
Publishing date	2020-07-20
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED