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Article ; Online: Strain accumulation and release associated with the occurrence of SSEs in the subduction zones of the Japanese Islands.

Kawabata, Hiroki / Yoshioka, Shoichi

2023 Volume 13, Issue 1, Page(s) 1379

Abstract: We investigated the spatiotemporal changes in strain associated with the occurrence of slow slip events (SSEs) in the subduction zones of the Japanese Islands and compared the spatial distribution of both the amount of strain accumulated for the period ... ...

Abstract	We investigated the spatiotemporal changes in strain associated with the occurrence of slow slip events (SSEs) in the subduction zones of the Japanese Islands and compared the spatial distribution of both the amount of strain accumulated for the period before and during the SSEs release using time series data from the Global Navigation Satellite System (GNSS). In this study, four SSEs were analysed: the Tokai long-term SSE (2000-2005), the Boso-Oki short-term SSE (2007), and the Bungo Channel long-term SSEs (2009-2011 and 2018-2019). As a result, we found strong negative correlations for all four dilatations before and during SSE occurrence. For these dilatations, we estimated the amount of strain released at the time of occurrence of the SSE relative to that accumulated during the period prior to the SSE. The result indicates that not all the accumulated strain before the SSEs was released when the SSEs occurred. Moreover, it is highly likely that the strain released by SSE is not only due to the strain accumulation just below the SSE occurrence region, but also due to the strain accumulation on the shallower plate boundary, which is a seismogenic zone for a future megathrust earthquake.
Language	English
Publishing date	2023-01-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-28016-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Inhibition of RNA Phosphodiester Backbone Cleavage in the Presence of Organic Cations of Different Sizes.

Yoshioka, Senri / Doi, Asuka / Nakano, Shu-Ichi

Chembiochem : a European journal of chemical biology

2024 , Page(s) e202400276

Abstract: Living cells contain various types of organic cations that may interact with nucleic acids. In order to understand the nucleic acid-binding properties of organic cations of different sizes, we investigated the ability of simple organic cations to inhibit ...

Abstract	Living cells contain various types of organic cations that may interact with nucleic acids. In order to understand the nucleic acid-binding properties of organic cations of different sizes, we investigated the ability of simple organic cations to inhibit the RNA phosphodiester bond cleavage promoted by Mg2+, Pb2+, and RNA-cleaving serum proteins. Kinetic analysis using chimeric DNA-RNA oligonucleotides showed that the cleavage at ribonucleotide sites was inhibited in the presence of monovalent cations comprising alkyl chains or benzene rings. The comparison of the cleavage rates in the presence of quaternary ammonium and phosphonium ions indicated that the steric hindrance effect of organic cations on their binding to the RNA backbone is significant when the cation size is larger than the phosphate-phosphate distance of a single-stranded nucleic acid. The cleavage inhibition was also observed for ribonucleotides located in long loops but not in short loops of oligonucleotide structures, indicating less efficient binding of bulky cations to structurally constrained regions. These results reveal the unique nucleic acid-binding properties of bulky cations distinct from those of metal ions.
Language	English
Publishing date	2024-05-06
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2020469-3
ISSN	1439-7633 ; 1439-4227
ISSN (online)	1439-7633
ISSN	1439-4227
DOI	10.1002/cbic.202400276
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Article ; Online: Spontaneous echo contrast and decreased umbilical vein blood flow may predict thrombus formation in fetal intra-abdominal umbilical vein varix.

Takaishi, Yu / Kawasaki, Kaoru / Uematsu, Kazuhiko / Yoshioka, Shinya

Journal of medical ultrasonics (2001)

2024

Abstract: Purpose: Fetal intra-abdominal umbilical vein varix (FIUVV) can cause thrombosis, fetal growth restriction (FGR), and intrauterine fetal death (IUFD). However, its management and evaluation to avoid fetal risks have not been elucidated. The aim of this ... ...

Abstract	Purpose: Fetal intra-abdominal umbilical vein varix (FIUVV) can cause thrombosis, fetal growth restriction (FGR), and intrauterine fetal death (IUFD). However, its management and evaluation to avoid fetal risks have not been elucidated. The aim of this study was to develop a novel method to evaluate fetal risks, including FGR and fetal dysfunction via frequent ultrasound examinations. Methods: A 28-year-old pregnant woman was diagnosed with FIUVV via ultrasound at 26 weeks of gestation and admitted to our hospital. Ultrasound examinations were performed two to three times weekly to evaluate size and shape of the FIUVV and umbilical vein blood flow at the inflow and outflow sites of the FIUVV. Results: The outflow site of the FIUVV was constricted and collapsed, and the blood flow velocity at the inflow site of the FIUVV was decreased. At 32 weeks of gestation, spontaneous echo contrast (SEC), which indicates increased echogenicity, appeared. At 35 weeks of gestation, the patient noticed decreased fetal movement, and CTG showed non-reassuring fetal status. SEC in the FIUVV was remarkable. Fetal movement could not be confirmed at ultrasound. Cesarean section was performed and a 1,854-g healthy infant was delivered with an umbilical cord arterial pH of 7.266. Conclusion: The echographic changes, such as decreased umbilical vein blood flow and SEC, in FIUVV observed in this case could indicate thrombus formation, which can lead to fetal dysfunction. Frequent ultrasound examinations can help determine the timing of delivery and improve the neonatal prognosis.
Language	English
Publishing date	2024-03-26
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1396630-3
ISSN	1613-2254 ; 0287-0592 ; 1346-4523
ISSN (online)	1613-2254
ISSN	0287-0592 ; 1346-4523
DOI	10.1007/s10396-024-01428-w
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Article ; Online: Spatiotemporal slip distributions associated with the 2018-2019 Bungo Channel long-term slow slip event inverted from GNSS data.

Seshimo, Yukinari / Yoshioka, Shoichi

Scientific reports

2022 Volume 12, Issue 1, Page(s) 343

Abstract: Long-term slow slip events (L-SSEs) have repeatedly occurred beneath the Bungo Channel in southwestern Japan with durations of several months to a couple of years, with a recurrence interval of approximately 6 years. We estimated the spatiotemporal slip ... ...

Abstract	Long-term slow slip events (L-SSEs) have repeatedly occurred beneath the Bungo Channel in southwestern Japan with durations of several months to a couple of years, with a recurrence interval of approximately 6 years. We estimated the spatiotemporal slip distributions of the 2018-2019 Bungo Channel L-SSE by inverting processed GNSS time series data. This event was divided into two subevents, with the first on the southwest side of the Bungo Channel from 2018.3 to 2018.7 and the second beneath the Bungo Channel from 2018.8 to 2019.4. Tectonic tremors became active on the downdip side of the L-SSE occurrence region when large slow slips took place beneath the Bungo Channel. Compared with the previous Bungo Channel L-SSEs, this spatiotemporal slip pattern and amount were similar to those of the 2002-2004 L-SSE. However, the slip expanded in the northeast and southwest directions in the latter half of the second subevent. The maximum amount of slip, the maximum slip velocity, the total released seismic moment, and the moment magnitude of the 2018-2019 L-SSE were estimated to be 28 cm, 54 cm/year, [Formula: see text] Nm, and 7.0, respectively, all of which were the largest among the 1996-1998, 2002-2004, 2009-2011, and 2018-2019 L-SSEs.
Language	English
Publishing date	2022-01-10
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-021-03982-6
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Article ; Online: Numerical modeling of subduction and evaluation of Philippine Sea Plate tectonic history along the Nankai Trough.

Moreno, E J / Manea, V C / Manea, M / Yoshioka, S / Suenaga, N / Bayona, A

Scientific reports

2023 Volume 13, Issue 1, Page(s) 18313

Abstract: The subduction of the Philippine Sea (PHS) plate along the Nankai Trough in in southwest Japan is a relatively recent process compared with subduction along the Japan Trench in northeast Japan. However, the tectonic evolution of the PHS plate along the ... ...

Abstract	The subduction of the Philippine Sea (PHS) plate along the Nankai Trough in in southwest Japan is a relatively recent process compared with subduction along the Japan Trench in northeast Japan. However, the tectonic evolution of the PHS plate along the Nankai Trough is still controversial and not fully understood. There are several competing hypotheses based on different estimates for the time variations of convergence rate and plate age. Our study employs numerical modelling of subduction in order to evaluate the slab evolution for the last 15 Myr and aims to evaluate each tectonic scenario against the present-day slab geometry along a profile passing through the Shikoku and Chugoku regions. The modelling strategy involves a parameter study where subduction initiation and various subduction parameters are analyzed in terms of subduction geometry evolution. Two-dimensional visco-elasto-plastic numerical simulations of spontaneous bending subduction predict that convergence rate and plate age variations play an important role in the evolution of subduction geometry. Modeling results after 15 Myr of evolution reveal that the tectonic model based on a high convergence rate between ~ 15 Ma and ~ 3 Ma produces a slab geometry that agrees well with the observed present-day slab shape specific for the Shikoku and Chugoku regions.
Language	English
Publishing date	2023-10-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-45370-2
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Article ; Online: The geodynamic origin of Los Humeros volcanic field in Mexico: insights from numerical simulations.

Bayona, A / Manea, V C / Manea, M / Yoshioka, S / Moreno, E / Suenaga, N

Scientific reports

2023 Volume 13, Issue 1, Page(s) 22284

Abstract: Compared to normal arc-related volcanic eruptions, the formation of a volcanic caldera is a relatively atypical event. During caldera formation a series of large volumes of magma are erupted, reducing the structural support for the rock above the magma ... ...

Abstract	Compared to normal arc-related volcanic eruptions, the formation of a volcanic caldera is a relatively atypical event. During caldera formation a series of large volumes of magma are erupted, reducing the structural support for the rock above the magma chamber and creating a large depression at the surface called caldera. Los Humeros volcanic field (LHVF) represents one of the largest volcanic calderas in Mexico. It is located some 400 km from the trench at the eastern edge of the Trans Mexican Volcanic Belt where the depth to the Cocos slab is more than 300 km. In this study we employ high-resolution two-dimensional thermomechanical numerical simulations of magma intrusions and a horizontal tectonic strain rate to better understand the influence of crustal deformation for the formation of Los Humeros caldera. A minimum number of three thermal anomaly pulses of hydrated mantle material (with diameter of 15 km or more) and a regional strain rate of 7.927 × 10
Language	English
Publishing date	2023-12-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-49292-x
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Article: Analysis of Urinary Retention Caused by Selective β 3-adrenoceptor Agonists Using the Japanese Adverse Drug Event Report Database (JADER).

Kawazoe, T / Ishida, T / Jobu, K / Kawada, K / Yoshioka, S / Miyamura, M

Die Pharmazie

2023 Volume 78, Issue 5, Page(s) 56–62

Abstract: Overactive bladder (OAB) is a frequent chronic disorder which impairs quality of life by frequent, uncontrollable urination. Newly developed selectiveβ 3-adrenoceptor agonists (sβ 3-agonists) have the same efficacy in treating OAB but significantly fewer ...

Abstract	Overactive bladder (OAB) is a frequent chronic disorder which impairs quality of life by frequent, uncontrollable urination. Newly developed selectiveβ 3-adrenoceptor agonists (sβ 3-agonists) have the same efficacy in treating OAB but significantly fewer side effects than the traditionally used anti-muscarinics. However, safety data on these compounds are scarce. In this study, we analysed the occurrence of adverse effects in patients taking sβ 3-agonists and their characteristics using the JADER database. The most frequently reported adverse effect associated with the use of sβ 3-agonists was urinary retention [mirabegron; crude reporting odds ratios (ROR): 62.1, 95% confidence interval (CI): 52.0-73.6, P<0.001, vibegron; crude ROR: 250, 95% CI : 134-483, P<0.001]. Data from patients with urinary retention were stratified by sex. In both men and women, the rate of urinary retention was higher when using the mirabegron/anti-muscarinic drug when compared to mirabegron monotherapy; its occurrence was higher in men with a history of benign prostatic hypertrophy than in those without. Weibull analysis showed that approximately 50% of sβ 3 agonist-induced urinary retention occurred within 15 days after initiation of treatment, and then gradually decreased. Although sβ 3-agonists are useful against OAB, they may induce several side effects, especially urinary retention, which can further evolve into more severe conditions. Urinary retention occurs more frequently in patients concomitantly taking medication that either increases urethral resistance or has organic factors that block the urethra. When using sβ 3-agonists, the concomitantly used medications and underlying diseases should be thoroughly reviewed, and safety monitoring should be instituted early during the treatment.
MeSH term(s)	Male ; Humans ; Female ; Urinary Retention/chemically induced ; Urinary Retention/epidemiology ; Urinary Retention/complications ; Muscarinic Antagonists ; Quality of Life ; East Asian People ; Adrenergic beta-3 Receptor Agonists/adverse effects ; Urinary Bladder, Overactive/drug therapy ; Urinary Bladder, Overactive/chemically induced ; Urinary Bladder, Overactive/complications ; Drug-Related Side Effects and Adverse Reactions ; Receptors, Adrenergic/therapeutic use ; Treatment Outcome
Chemical Substances	mirabegron (MVR3JL3B2V) ; Muscarinic Antagonists ; Adrenergic beta-3 Receptor Agonists ; Receptors, Adrenergic
Language	English
Publishing date	2023-05-15
Publishing country	Germany
Document type	Journal Article
ZDB-ID	208793-5
ISSN	0031-7144
ISSN	0031-7144
DOI	10.1691/ph.2023.3509
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Conference proceedings ; Online: 3-D thermal structure and dehydration in the southern Chile subduction zone and relation to interplate earthquakes and the volcanic chain

Iwamoto, K. / Suenaga, N. / Yoshioka, S. / Ortega-Culaciati, F.

XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)

2023

Abstract: In the southern Chile subduction zone, the Nazca plate is subducting beneath the South American plate. This region was recently struck by great megathrust earthquakes and is characterized by the existence of a volcanic chain. In this study, we calculated ...

Abstract	In the southern Chile subduction zone, the Nazca plate is subducting beneath the South American plate. This region was recently struck by great megathrust earthquakes and is characterized by the existence of a volcanic chain. In this study, we calculated the three-dimensional thermal structure in the southern Chile subduction zone associated with the subduction of the Nazca plate by using numerical simulations. Based on the obtained temperature distribution, we determined the temperature ranges for the coseismic slips of the two megathrust earthquakes and temperatures at the hypocentres of the interplate earthquakes. In addition, the distributions of the water content and dehydration gradient were calculated by using the phase diagrams and were compared with the location of the volcanic chain. As a result, we found that coseismic slips occurred only at temperatures lower than the 350 °C isotherm. This finding occurs because the effective friction coefficient increases as the slip velocity increases at the plate boundary where the temperature is higher than 350 °C. In addition, the hydrous minerals in and above the slab release fluids through dehydration reactions, which decrease the melting point of the mantle wedge, contributing to the formation of the volcanic chain.
Subject code	550
Language	English
Publishing country	de
Document type	Conference proceedings ; Online
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Article ; Online: A new method for reduction of incarcerated gravid uterus.

Tanimura, Masaya / Sakiyama, Asuka / Yoshioka, Shinya

European journal of obstetrics & gynecology and reproductive biology: X

2023 Volume 18, Page(s) 100201

Language	English
Publishing date	2023-06-03
Publishing country	Netherlands
Document type	Journal Article
ISSN	2590-1613
ISSN (online)	2590-1613
DOI	10.1016/j.eurox.2023.100201
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Article ; Online: Joint Coordination With a Change in Task Constraint During Accurate Overhead Throwing.

Kimura, Arata / Yoshioka, Shinsuke / Fukashiro, Senshi

Journal of applied biomechanics

2023 Volume 39, Issue 3, Page(s) 169–178

Abstract: In sports situations, players may be required to throw at different speeds. The question of how skilled players throw the ball accurately to the desired location under different speed conditions is of interest to biomechanics researchers. Previous ... ...

Abstract	In sports situations, players may be required to throw at different speeds. The question of how skilled players throw the ball accurately to the desired location under different speed conditions is of interest to biomechanics researchers. Previous research suggested that throwers use different types of joint coordination. However, joint coordination with a change in throwing speed has not been studied. Here, we show the effects of changes in throwing speed on joint coordination during accurate overhead throwing. Participants were seated on a low chair with their trunk fixed and threw a baseball aimed at a target under 2 different speed conditions (slow and fast). In the slow condition, the elbow flexion/extension angle coordinated with other joint angles and angular velocities to reduce the variability of the vertical hand velocity. In the fast condition, the shoulder internal/external rotation angle and the shoulder horizontal flexion/extension angular velocity coordinated with other joint angles and angular velocities to reduce the variability of the vertical hand velocity. These results showed that joint coordination differed with changes in throwing speed, indicating that joint coordination is not always fixed, but may differ depending on the task constraints, such as throwing speed.
MeSH term(s)	Humans ; Elbow Joint ; Shoulder ; Elbow ; Shoulder Joint ; Upper Extremity ; Baseball ; Biomechanical Phenomena
Language	English
Publishing date	2023-05-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	1145288-2
ISSN	1543-2688 ; 1065-8483
ISSN (online)	1543-2688
ISSN	1065-8483
DOI	10.1123/jab.2022-0130
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