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  1. Book ; Thesis: Implication of Notch-DLL4 signaling in endothelial angiogenesis of cerebral cavernous malformations

    You, Chao

    2016  

    Institution Universität Duisburg-Essen
    Author's details vorgelegt von Chao You
    Language English
    Size 85 Blätter, Diagramme
    Publishing place Duisburg ; Essen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Duisburg-Essen, 2016
    HBZ-ID HT019029783
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Shared auditors, information asymmetry degree, and mergers and acquisitions value creation.

    You, Chunhui

    Frontiers in psychology

    2022  Volume 13, Page(s) 921581

    Abstract: The social network is an important factor that affects the value creation of mergers and acquisitions (M&A). The M&A events of China's Listed Companies in 2011-2018 were used as research samples, and this study used the ordinary least square method to ... ...

    Abstract The social network is an important factor that affects the value creation of mergers and acquisitions (M&A). The M&A events of China's Listed Companies in 2011-2018 were used as research samples, and this study used the ordinary least square method to test the value creation effect of shared auditors. First, it analyzed the impact of shared auditors on the current, short-term, and long-term M&A value creation. Second, it analyzed the moderating effect of information asymmetry degree. The research results show that shared auditors can increase the enterprise value of both sides of M&A. In addition, related M&A and industry attributes can moderate the relationship between shared auditors and M&A value creation. When the M&A are unrelated and in different industries, shared auditors play a more significant role in the value creation of M&A that have more asymmetric information.
    Language English
    Publishing date 2022-08-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.921581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Healthcare-associated carbapenem-resistant Klebsiella pneumoniae infections are associated with higher mortality compared to carbapenem-susceptible K. pneumoniae infections in the intensive care unit: a retrospective cohort study.

    Yao, Y / Zha, Z / Li, L / Tan, H / Pi, J / You, C / Liu, B

    The Journal of hospital infection

    2024  Volume 148, Page(s) 30–38

    Abstract: Background: Klebsiella pneumoniae (KP) is an opportunistic pathogen causing severe pneumonia and sepsis. Carbapenem-resistant KP (CRKP) has become a major pathogen in many centres.: Aim: To investigate the association between carbapenem resistance ... ...

    Abstract Background: Klebsiella pneumoniae (KP) is an opportunistic pathogen causing severe pneumonia and sepsis. Carbapenem-resistant KP (CRKP) has become a major pathogen in many centres.
    Aim: To investigate the association between carbapenem resistance and the mortality rate, length of stay, and hospital cost in patients with Klebsiella pneumoniae infection.
    Methods: The retrospective cohort study was conducted in the intensive care units of a large teaching tertiary hospital in southwest China between January 1
    Findings: The study included 282 adult patients with KP infection (135 CSKP; 147 CRKP). CRKP-infected patients demonstrated higher mortality risk (unadjusted hazard ratio (aHR): 1.980; 95% confidence interval (CI): 1.206-3.248; P = 0.007; aHR: 1.767; 95% CI: 1.038-3.005; P = 0.036) compared to CSKP-infected patients. Stratified analysis, according to type of KP infection, revealed that patients with healthcare-associated CRKP infection had a significantly higher mortality risk compared to those with CSKP infection (log-rank P = 0.015). Patients with CRKP infection had longer hospital stays than those infected with CSKP (adjusted mean: 38.74 vs 29.71 days; P = 0.003), and hospital-related expenses were notably higher among CRKP patients than CSKP patients (adjusted cost: £40,126.73 vs 25,713.74; P < 0.001).
    Conclusion: CRKP infections increase mortality rates, prolong hospital stays, and raise healthcare costs. Healthcare facilities should adopt targeted strategies, including curtailing pre-infection hospitalization periods and managing medications more judiciously.
    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 779366-2
    ISSN 1532-2939 ; 0195-6701
    ISSN (online) 1532-2939
    ISSN 0195-6701
    DOI 10.1016/j.jhin.2024.03.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The biomarkers discovery of hyperuricemia and gout: proteomics and metabolomics.

    Wu, Xinghong / You, Chongge

    PeerJ

    2023  Volume 11, Page(s) e14554

    Abstract: Background: Hyperuricemia and gout are a group of disorders of purine metabolism. In recent years, the incidence of hyperuricemia and gout has been increasing, which is a severe threat to people's health. Several studies on hyperuricemia and gout in ... ...

    Abstract Background: Hyperuricemia and gout are a group of disorders of purine metabolism. In recent years, the incidence of hyperuricemia and gout has been increasing, which is a severe threat to people's health. Several studies on hyperuricemia and gout in proteomics and metabolomics have been conducted recently. Some literature has identified biomarkers that distinguish asymptomatic hyperuricemia from acute gout or remission of gout. We summarize the physiological processes in which these biomarkers may be involved and their role in disease progression.
    Methodology: We used professional databases including PubMed, Web of Science to conduct the literature review. This review addresses the current landscape of hyperuricemia and gout biomarkers with a focus on proteomics and metabolomics.
    Results: Proteomic methods are used to identify differentially expressed proteins to find specific biomarkers. These findings may be suggestive for the diagnosis and treatment of hyperuricemia and gout to explore the disease pathogenesis. The identified biomarkers may be mediators of the link between hyperuricemia, gout and kidney disease, metabolic syndrome, diabetes and hypertriglyceridemia. Metabolomics reveals the main influential pathways through small molecule metabolites, such as amino acid metabolism, lipid metabolism, or other characteristic metabolic pathways. These studies have contributed to the discovery of Chinese medicine. Some traditional Chinese medicine compounds can improve the metabolic disorders of the disease.
    Conclusions: We suggest some possible relationships of potential biomarkers with inflammatory episodes, complement activation, and metabolic pathways. These biomarkers are able to distinguish between different stages of disease development. However, there are relatively few proteomic as well as metabolomic studies on hyperuricemia and gout, and some experiments are only primary screening tests, which need further in-depth study.
    MeSH term(s) Humans ; Hyperuricemia/diagnosis ; Proteomics ; Gout/diagnosis ; Uric Acid ; Biomarkers
    Chemical Substances Uric Acid (268B43MJ25) ; Biomarkers
    Language English
    Publishing date 2023-01-06
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2703241-3
    ISSN 2167-8359 ; 2167-8359
    ISSN (online) 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.14554
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: ASO Author Reflections: A Safe and Feasible Procedure for Bladder Cancer-Extraperitoneal Radical Cystectomy.

    You, Chengyu / Dong, Zhilong

    Annals of surgical oncology

    2023  Volume 30, Issue 9, Page(s) 5942

    MeSH term(s) Humans ; Cystectomy ; Urinary Bladder Neoplasms/surgery ; Urinary Bladder ; Treatment Outcome
    Language English
    Publishing date 2023-06-21
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-13789-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Unintended consequences of administrative decentralization on air pollution: evidence from county power expansion in China.

    You, Chen / Zhang, Ziyan

    Environmental science and pollution research international

    2023  Volume 30, Issue 43, Page(s) 98271–98287

    Abstract: How to reduce air pollution is an essential topic of environmental governance. Existing research has predominantly concentrated on the decentralization effect within the environmental field, leaving a gap in exploring non-environmental decentralization ... ...

    Abstract How to reduce air pollution is an essential topic of environmental governance. Existing research has predominantly concentrated on the decentralization effect within the environmental field, leaving a gap in exploring non-environmental decentralization effects. This paper exploits a quasi-experiment of "counties power expansion (CPE)" reform in China to examine the effect of administrative decentralization on air pollution. Administrative decentralization will reorganize authority in economic and social matters and redistribute fiscal responsibility and resources for specific targets among multilevel governments. Employing a county-level dataset from 1999 to 2019 in China, we find that administrative decentralization significantly raises air pollution by about 2%. Our results further suggest that air pollution is mainly attributed to the increment of resource input and firm expansion. We find that geographical location will influence the air pollution effect. The policymaker should consider an inclusive intuitional design when launching administrative decentralization.
    MeSH term(s) Conservation of Natural Resources ; Environmental Policy ; China ; Air Pollution ; Politics
    Language English
    Publishing date 2023-08-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-29403-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Delayed wildfires in 2020 promote snowpack melting in the western United States.

    You, Chao / Xu, Chao

    Proceedings of the National Academy of Sciences of the United States of America

    2023  Volume 120, Issue 2, Page(s) e2218087120

    MeSH term(s) United States ; Wildfires ; Forests
    Language English
    Publishing date 2023-01-03
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2218087120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Agricultural expansion dominates rapid increases in cropland fires in Asia.

    Xu, Chao / You, Chao

    Environment international

    2023  Volume 179, Page(s) 108189

    Abstract: Asia contains 58 % of the global population and approximately 39 % of the world's cropland, making evaluation of the spatiotemporal variability patterns in cropland fire critical for understanding the interplay between crop residue burning and human ... ...

    Abstract Asia contains 58 % of the global population and approximately 39 % of the world's cropland, making evaluation of the spatiotemporal variability patterns in cropland fire critical for understanding the interplay between crop residue burning and human activity in Asia. Although agricultural expansion and intensification have contributed to an overall decline in vegetation fires worldwide since the late 1990s, burned area by cropland fires in Asia has expanded by more than 19 % over the past two decades. India accounts for about 32 % of cropland fires in Asia, and the burned area has increased by more than two-thirds since 2003, particularly increased around 80 % during the two major cereal harvest seasons of March-May and October-November. In comparison, cropland fires have increased by <6 % in China since 2003, and there has been a marked downward trend in burned area in June due to the intensive implementation of the nationwide bans on open-land crop straw burning. The expansion of agricultural harvests is primarily responsible for the rapid increase in cropland fires in Asia, notably in India, where agricultural intensification is occurring with population growth and economic development in recent years, and crop straw burning should be strictly controlled in the future.
    MeSH term(s) Humans ; Asia ; India ; China ; Agriculture ; Edible Grain
    Language English
    Publishing date 2023-09-06
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 554791-x
    ISSN 1873-6750 ; 0160-4120
    ISSN (online) 1873-6750
    ISSN 0160-4120
    DOI 10.1016/j.envint.2023.108189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Diversity, Community Structure, and Antagonism of Endophytic Fungi from Asymptomatic and Symptomatic Mongolian Pine Trees.

    Ren, Ninghong / Wang, Lei / You, Chongjuan

    Journal of fungi (Basel, Switzerland)

    2024  Volume 10, Issue 3

    Abstract: Diplodia tip blight, caused ... ...

    Abstract Diplodia tip blight, caused by
    Language English
    Publishing date 2024-03-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof10030212
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Enhanced adsorption of Pb

    Xie, Ning / Wang, Haiming / You, Changfu

    Environmental science and pollution research international

    2024  

    Abstract: Lead is one of the primary pollutants found in water and poses significant toxicity risks to humans; thus, it is necessary to investigate techniques for removing it economically and efficiently. In order to enhance the removal capacity of ... ...

    Abstract Lead is one of the primary pollutants found in water and poses significant toxicity risks to humans; thus, it is necessary to investigate techniques for removing it economically and efficiently. In order to enhance the removal capacity of Pb
    Language English
    Publishing date 2024-04-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-33047-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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