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Book ; Online: Gels for Oil and Gas Industry Applications

You, Qing / Zhao, Guang / Sun, Xindi

2022

Keywords	Technology: general issues ; viscoelastic surfactants ; wormlike micelles ; gels ; viscoelasticity ; oil recovery ; hydraulic fracturing ; clean fracturing fluids ; responsiveness to hydrocarbons ; oligomeric surfactants ; nanoparticle/VES fluids ; polymer/VES fluids ; plant press slag (PPS) ; carboxymethylation ; mixture of carboxymethyl cellulose and carboxymethyl starch (CMCS) ; filtrate reducer ; drilling fluids ; fumaric acid sludge (FAS) ; free radical copolymerization ; filtrate loss reducer ; organic wastewater of phthalic anhydride ; oil well drilling fluids ; wellbore stability ; biopolymer ; encapsulator ; water-based drilling fluids ; chemical strengthening ; weak gel ; numerical simulation ; displacement efficiency ; filtration reducer ; high temperature ; water-based drilling fluid ; nanomaterials ; calcium carbonate ; polymer gel ; water coning ; chemical packer ; horizontal well ; offshore oil-field application ; enhanced gel system ; enhanced foam system ; heterogeneous reservoir ; plugging adaptability ; enhanced oil recovery ; low temperature ; high salinity ; conformance control ; salt resistance ; phenolic ; gel ; compound ; staged ; gelling acid fracturing ; temporary plugging ; n/a
Language	English
Size	1 electronic resource (200 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English
HBZ-ID	HT030380560
ISBN	9783036551951 ; 3036551956
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: AcousticRobots: Smart acoustically powered micro-/nanoswimmers for precise biomedical applications.

Wu, Gege / Xian, Wei / You, Qing / Zhang, Jingjing / Chen, Xiaoyuan

Advanced drug delivery reviews

2024 Volume 207, Page(s) 115201

Abstract: Although nanotechnology has evolutionarily progressed in biomedical field over the past decades, achieving satisfactory therapeutic effects remains difficult with limited delivery efficiency. Ultrasound could provide a deep penetration and maneuverable ... ...

Abstract	Although nanotechnology has evolutionarily progressed in biomedical field over the past decades, achieving satisfactory therapeutic effects remains difficult with limited delivery efficiency. Ultrasound could provide a deep penetration and maneuverable actuation to efficiently power micro-/nanoswimmers with little harm, offering an emerging and fascinating alternative to the active delivery platform. Recent advances in novel fabrication, controllable concepts like intelligent swarm and the integration of hybrid propulsions have promoted its function and potential for medical applications. In this review, we will summarize the mechanisms and types of ultrasonically propelled micro/nanorobots (termed here as "AcousticRobots"), including the interactions between AcousticRobots and acoustic field, practical design considerations (e.g., component, size, shape), the synthetic methods, surface modification, controllable behaviors, and the advantages when combined with other propulsion approaches. The representative biomedical applications of functional AcousticRobots are also highlighted, including drug delivery, invasive surgery, eradication on the surrounding bio-environment, cell manipulation, detection, and imaging, etc. We conclude by discussing the challenges and outlook of AcousticRobots in biomedical applications.
MeSH term(s)	Humans ; Nanotechnology/methods ; Drug Delivery Systems/methods
Language	English
Publishing date	2024-02-06
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	639113-8
ISSN	1872-8294 ; 0169-409X
ISSN (online)	1872-8294
ISSN	0169-409X
DOI	10.1016/j.addr.2024.115201
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Numerical Simulation of Proppant Transport in Major and Branching Fractures Based on CFD-DEM.

Zuo, Luo / Li, Xiaolong / Han, Zhongxi / You, Qing / Liu, Xiaoqiang

ACS omega

2024 Volume 9, Issue 11, Page(s) 13163–13171

Abstract: This research investigated the effect of branching fracture, proppant, and fracturing fluid on proppant transport based on the CFD-DEM coupling model. The obtained results show that the balance height of embankment in the major fracture decreases ... ...

Abstract	This research investigated the effect of branching fracture, proppant, and fracturing fluid on proppant transport based on the CFD-DEM coupling model. The obtained results show that the balance height of embankment in the major fracture decreases gradually with increasing angle between major and branching fractures, while it increases gradually in the branching fracture. This is because the additional resistance of fracturing fluid flow at the joint increases with increasing angle, leading to the decrease of the fracturing fluid velocity. The proppant is prone to settling in branching fractures, resulting in the increase of embankment height in the branching fracture. At angles of 45, 60, and 90°, as the diameter of the proppant increases from 0.8 to 1.1 mm, the balance height of embankment increases slightly in the major fracture, while it decreases in the branching fracture. The frictional resistance of the fracture wall enhances the difficulty of large proppant entering the branching fracture, resulting in a decrease in the amount of proppant entering the branching fracture and a decrease of the balance height of embankment in the branching fracture. In the low-viscosity fracturing fluid, the proppant quickly deposits at the bottom of the fracture as it enters the fracture. Improving the viscosity of the fracturing fluid can significantly enhance its ability to transport the proppant. The proppant is less likely to quickly settle in high-viscosity fracturing fluids, especially when the fracturing fluid viscosity exceeds 50 mPa·s.
Language	English
Publishing date	2024-03-08
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.3c09710
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Progress on Physical Field-Regulated Micro/Nanomotors for Cardiovascular and Cerebrovascular Disease Treatment.

You, Qing / Shao, Xinyue / Wang, Jinping / Chen, Xiaoyuan

Small methods

2023 Volume 7, Issue 10, Page(s) e2300426

Abstract: Cardiovascular and cerebrovascular diseases (CCVDs) are two major vasculature-related diseases that seriously affect public health worldwide, which can cause serious death and disability. Lack of targeting effect of the traditional CCVD treatment drugs ... ...

Abstract	Cardiovascular and cerebrovascular diseases (CCVDs) are two major vasculature-related diseases that seriously affect public health worldwide, which can cause serious death and disability. Lack of targeting effect of the traditional CCVD treatment drugs may damage other tissues and organs, thus more specific methods are needed to solve this dilemma. Micro/nanomotors are new materials that can convert external energy into driving force for autonomous movement, which can not only enhance the penetration depth and retention rates, but also increase the contact areas with the lesion sites (such as thrombus and inflammation sites of blood vessels). Physical field-regulated micro/nanomotors using the physical energy sources with deep tissue penetration and controllable performance, such as magnetic field, light, and ultrasound, etc. are considered as the emerging patient-friendly and effective therapeutic tools to overcome the limitations of conventional CCVD treatments. Recent efforts have suggested that physical field-regulated micro/nanomotors on CCVD treatments could simultaneously provide efficient therapeutic effect and intelligent control. In this review, various physical field-driven micro/nanomotors are mainly introduced and their latest advances for CCVDs are highlighted. Last, the remaining challenges and future perspectives regarding the physical field-regulated micro/nanomotors for CCVD treatments are discussed and outlined.
MeSH term(s)	Humans ; Nanotechnology/methods ; Nanostructures/therapeutic use ; Cerebrovascular Disorders/therapy ; Cardiovascular Diseases/therapy ; Movement
Language	English
Publishing date	2023-06-30
Publishing country	Germany
Document type	Journal Article ; Review
ISSN	2366-9608
ISSN (online)	2366-9608
DOI	10.1002/smtd.202300426
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Transition Metal-Based Therapies for Inflammatory Diseases.

Song, Yilin / You, Qing / Chen, Xiaoyuan

Advanced materials (Deerfield Beach, Fla.)

2023 Volume 35, Issue 39, Page(s) e2212102

Abstract: Inflammatory disease (ID) is a general term that covers all diseases in which chronic inflammation performs as the major manifestation of pathogenesis. Traditional therapies based on the anti-inflammatory and immunosuppressive drugs are palliative with ... ...

Abstract	Inflammatory disease (ID) is a general term that covers all diseases in which chronic inflammation performs as the major manifestation of pathogenesis. Traditional therapies based on the anti-inflammatory and immunosuppressive drugs are palliative with the short-term remission. The emergence of nanodrugs has been reported to solve the potential causes and prevent recurrences, thus holding great potential for the treatment of IDs. Among various nanomaterial systems, transition metal-based smart nanosystems (TMSNs) with unique electronic structures possess therapeutic advantages owing to their large surface area to volume ratio, high photothermal conversion efficiency, X-ray absorption capacity, and multiple catalytic enzyme activities. In this review, the rationale, design principle, and therapeutic mechanisms of TMSNs for treatments of various IDs are summarized. Specifically, TMSNs can not only be designed to scavenge danger signals, such as reactive oxygen and nitrogen species and cell-free DNA, but also can be engineered to block the mechanism of initiating inflammatory responses. In addition, TMSNs can be further applied as nanocarriers to deliver anti-inflammatory drugs. Finally, the opportunities and challenges of TMSNs are discussed, and the future directions of TMSN-based ID treatment for clinical applications are emphasized.
MeSH term(s)	Nanostructures ; Transition Elements/therapeutic use ; Anti-Inflammatory Agents/therapeutic use
Chemical Substances	Transition Elements ; Anti-Inflammatory Agents
Language	English
Publishing date	2023-08-02
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	1474949-X
ISSN	1521-4095 ; 0935-9648
ISSN (online)	1521-4095
ISSN	0935-9648
DOI	10.1002/adma.202212102
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Enhanced photodynamic therapy through multienzyme-like MOF for cancer treatment.

Lv, Letian / Fu, Zhao / You, Qing / Xiao, Wei / Wang, Huayi / Wang, Chen / Yang, Yanlian

Frontiers in bioengineering and biotechnology

2024 Volume 11, Page(s) 1338257

Abstract: Overcoming resistance to apoptosis is a major challenge in cancer therapy. Recent research has shown that manipulating mitochondria, the organelles critical for energy metabolism in tumor cells, can increase the effectiveness of photodynamic therapy and ... ...

Abstract	Overcoming resistance to apoptosis is a major challenge in cancer therapy. Recent research has shown that manipulating mitochondria, the organelles critical for energy metabolism in tumor cells, can increase the effectiveness of photodynamic therapy and trigger apoptosis in tumor cells. However, there is currently insufficient research and effective methods to exploit mitochondrial damage to induce apoptosis in tumor cells and improve the effectiveness of photodynamic therapy. In this study, we present a novel nanomedicine delivery and therapeutic system called PyroFPSH, which utilizes a nanozymes-modified metal-organic framework as a carrier. PyroFPSH exhibits remarkable multienzyme-like activities, including glutathione peroxidase (GPx) and catalase (CAT) mimicry, allowing it to overcome apoptosis resistance, reduce endogenous glutathione levels, and continuously generate reactive oxygen species (ROS). In addition, PyroFPSH can serve as a carrier for the targeted delivery of sulfasalazine, a drug that can induce mitochondrial depolarization in tumor cells, thereby reducing oxygen consumption and energy supply in the mitochondria of tumor cells and weakening resistance to other synergistic treatment approaches. Our experimental results highlight the potential of PyroFPSH as a versatile nanoplatform in cancer treatment. This study expands the biomedical applications of nanomaterials as platforms and enables the integration of various novel therapeutic strategies to synergistically improve tumor therapy. It deepens our understanding of multienzyme-mimicking active nanocarriers and mitochondrial damage through photodynamic therapy. Future research can further explore the potential of PyroFPSH in clinical cancer treatment and improve its drug loading capacity, biocompatibility and targeting specificity. In summary, PyroFPSH represents a promising therapeutic approach that can provide new insights and possibilities for cancer treatment.
Language	English
Publishing date	2024-01-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2719493-0
ISSN	2296-4185
ISSN	2296-4185
DOI	10.3389/fbioe.2023.1338257
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Synthesis of Carboranylated Dihydropyrrolo[1,2-

Sun, Zhen-Zhen / Gao, Pan / Yang, Yong / Wang, Tao / Wu, Xiao-Jun / Wang, You-Qing

The Journal of organic chemistry

2024 Volume 89, Issue 5, Page(s) 3573–3579

Abstract: ... A ... ...

Abstract	A BF
Language	English
Publishing date	2024-02-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	123490-0
ISSN	1520-6904 ; 0022-3263
ISSN (online)	1520-6904
ISSN	0022-3263
DOI	10.1021/acs.joc.3c02443
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Ultrasound-nanovesicles interplay for theranostics.

Liu, Jingyi / You, Qing / Liang, Fuming / Ma, Lilusi / Zhu, Ling / Wang, Chen / Yang, Yanlian

Advanced drug delivery reviews

2024 Volume 205, Page(s) 115176

Abstract: Nanovesicles (NVs) are widely used in the treatment and diagnosis of diseases due to their excellent vascular permeability, good biocompatibility, high loading capacity, and easy functionalization. However, their yield and in vivo penetration depth ... ...

Abstract	Nanovesicles (NVs) are widely used in the treatment and diagnosis of diseases due to their excellent vascular permeability, good biocompatibility, high loading capacity, and easy functionalization. However, their yield and in vivo penetration depth limitations and their complex preparation processes still constrain their application and development. Ultrasound, as a fundamental external stimulus with deep tissue penetration, concentrated energy sources, and good safety, has been proven to be a patient-friendly and highly efficient strategy to overcome the restrictions of traditional clinical medicine. Recent research has shown that ultrasound can drive the generation of NVs, increase their yield, simplify their preparation process, and provide direct therapeutic effects and intelligent control to enhance the therapeutic effect of NVs. In addition, NVs, as excellent drug carriers, can enhance the targeting efficiency of ultrasound-based sonodynamic therapy or sonogenetic regulation and improve the accuracy of ultrasound imaging. This review provides a detailed introduction to the classification, generation, and modification strategies of NVs, emphasizing the impact of ultrasound on the formation of NVs and summarizing the enhanced treatment and diagnostic effects of NVs combined with ultrasound for various diseases.
MeSH term(s)	Humans ; Precision Medicine ; Drug Carriers ; Ultrasonography
Chemical Substances	Drug Carriers
Language	English
Publishing date	2024-01-09
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	639113-8
ISSN	1872-8294 ; 0169-409X
ISSN (online)	1872-8294
ISSN	0169-409X
DOI	10.1016/j.addr.2023.115176
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Single-cell transcriptomic analysis of radiation-induced lung injury in rat.

Shi, Xing-Yuan / Zhu, You-Qing / Liang, Chan-Jin / Chen, Ting / Shi, Zhi / Wang, Wei

Biomolecules & biomedicine

2024

Abstract: Radiation-induced lung injury (RILI) frequently occurs as a complication following radiotherapy for chest tumors like lung and breast cancers. However, the precise underlying mechanisms of RILI remain unclear. In this study, we generated RILI models in ... ...

Abstract	Radiation-induced lung injury (RILI) frequently occurs as a complication following radiotherapy for chest tumors like lung and breast cancers. However, the precise underlying mechanisms of RILI remain unclear. In this study, we generated RILI models in rats treated with a single dose of 20 Gy and examined lung tissues by single-cell RNA sequencing (scRNA-seq) 2 weeks post-radiation. Analysis of lung tissues revealed 18 major cell populations, indicating an increase in cell-cell communication following radiation exposure. Neutrophils, macrophages, and monocytes displayed distinct subpopulations and uncovered potential for pro-inflammatory effects. Additionally, endothelial cells exhibited a highly inflammatory profile and the potential for reactive oxygen species (ROS) production. Furthermore, smooth muscle cells (SMC) showed a high propensity for extracellular matrix (ECM) deposition. Our findings broaden the current understanding of RILI and highlight potential avenues for further investigation and clinical applications.
Language	English
Publishing date	2024-03-29
Publishing country	Bosnia and Herzegovina
Document type	Journal Article
ISSN	2831-090X
ISSN (online)	2831-090X
DOI	10.17305/bb.2024.10357
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Development and Applications of D-Amino Acid Derivatives-based Metabolic Labeling of Bacterial Peptidoglycan.

Zheng, Yongfang / Zhu, Xinyu / Jiang, Mingyi / Cao, Fangfang / You, Qing / Chen, Xiaoyuan

Angewandte Chemie (International ed. in English)

2024 Volume 63, Issue 17, Page(s) e202319400

Abstract: Peptidoglycan, an essential component within the cell walls of virtually all bacteria, is composed of glycan strands linked by stem peptides that contain D-amino acids. The peptidoglycan biosynthesis machinery exhibits high tolerance to various D-amino ... ...

Abstract	Peptidoglycan, an essential component within the cell walls of virtually all bacteria, is composed of glycan strands linked by stem peptides that contain D-amino acids. The peptidoglycan biosynthesis machinery exhibits high tolerance to various D-amino acid derivatives. D-amino acid derivatives with different functionalities can thus be specifically incorporated into and label the peptidoglycan of bacteria, but not the host mammalian cells. This metabolic labeling strategy is highly selective, highly biocompatible, and broadly applicable, which has been utilized in various fields. This review introduces the metabolic labeling strategies of peptidoglycan by using D-amino acid derivatives, including one-step and two-step strategies. In addition, we emphasize the various applications of D-amino acid derivative-based metabolic labeling, including bacterial peptidoglycan visualization (existence, biosynthesis, and dynamics, etc.), bacterial visualization (including bacterial imaging and visualization of growth and division, metabolic activity, antibiotic susceptibility, etc.), pathogenic bacteria-targeted diagnostics and treatment (positron emission tomography (PET) imaging, photodynamic therapy, photothermal therapy, gas therapy, immunotherapy, etc.), and live bacteria-based therapy. Finally, a summary of this metabolic labeling and an outlook is provided.
MeSH term(s)	Peptidoglycan/metabolism ; Bacteria/metabolism ; Amino Acids/chemistry ; Cell Wall/metabolism
Chemical Substances	Peptidoglycan ; Amino Acids
Language	English
Publishing date	2024-02-13
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	2011836-3
ISSN	1521-3773 ; 1433-7851
ISSN (online)	1521-3773
ISSN	1433-7851
DOI	10.1002/anie.202319400
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