Article ; Online: Optogenetic fMRI for Brain-Wide Circuit Analysis of Sensory Processing.
International journal of molecular sciences
2022 Volume 23, Issue 20
Abstract: Sensory processing is a complex neurological process that receives, integrates, and responds to information from one's own body and environment, which is closely related to survival as well as neurological disorders. Brain-wide networks of sensory ... ...
Abstract | Sensory processing is a complex neurological process that receives, integrates, and responds to information from one's own body and environment, which is closely related to survival as well as neurological disorders. Brain-wide networks of sensory processing are difficult to investigate due to their dynamic regulation by multiple brain circuits. Optogenetics, a neuromodulation technique that uses light-sensitive proteins, can be combined with functional magnetic resonance imaging (ofMRI) to measure whole-brain activity. Since ofMRI has increasingly been used for investigating brain circuits underlying sensory processing for over a decade, we systematically reviewed recent ofMRI studies of sensory circuits and discussed the challenges of optogenetic fMRI in rodents. |
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MeSH term(s) | Optogenetics/methods ; Magnetic Resonance Imaging/methods ; Brain Mapping/methods ; Brain/diagnostic imaging ; Brain/physiology ; Perception |
Language | English |
Publishing date | 2022-10-14 |
Publishing country | Switzerland |
Document type | Systematic Review ; Journal Article ; Review |
ZDB-ID | 2019364-6 |
ISSN | 1422-0067 ; 1422-0067 ; 1661-6596 |
ISSN (online) | 1422-0067 |
ISSN | 1422-0067 ; 1661-6596 |
DOI | 10.3390/ijms232012268 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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