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Article: [Research progress in saliva collection, analysis and its relationship with oral diseases].

Yu, C H / You, Z Y / Chen, S K / Han, Q / Chen, Y

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology

2019 Volume 54, Issue 5, Page(s) 344–349

Abstract: As one of the major body fluid, saliva has various components that can shift according to the systemic health state. With the atraumatic way of collection, saliva can be a promising media to help the detection of oral diseases. With the development of ... ...

Abstract	As one of the major body fluid, saliva has various components that can shift according to the systemic health state. With the atraumatic way of collection, saliva can be a promising media to help the detection of oral diseases. With the development of salivaomics and the application of unbiased, highly sensitive, and high throughout separation techniques for salivary components, there's now more possibilities for effective identification of biomarkers correlated with oral diseases. This review aimed to introduce the current state of saliva collection and detection techniques as well as their correlation with oral diseases, hoping to provide evidence for further research.
MeSH term(s)	Biomarkers ; Humans ; Mouth Diseases/diagnosis ; Research ; Saliva/chemistry
Chemical Substances	Biomarkers
Language	Chinese
Publishing date	2019-05-15
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	1027950-7
ISSN	1002-0098
ISSN	1002-0098
DOI	10.3760/cma.j.issn.1002-0098.2019.05.010
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Article: [An animal model of pump-controlled gastroenteric feeding].

You, Z Y

Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns

1989 Volume 5, Issue 4, Page(s) 287–8, 319

Abstract: A model for the study of gastroenteric feedings was established in guinea pigs. The model consists of guinea pig with gastrostomy tube and pump-controlled continuous enteral infusion system, with a swivel between the gastrostomy tube and pump system, so ... ...

Abstract	A model for the study of gastroenteric feedings was established in guinea pigs. The model consists of guinea pig with gastrostomy tube and pump-controlled continuous enteral infusion system, with a swivel between the gastrostomy tube and pump system, so that the guinea-pig could move freely in the cage during the experimental period. We used this model for continuous gastroenteric feeding study lasting 2 weeks, and the mortality of animal was low. It is simple, easy to operate, inexpensive and suitable for the experiment of gastroenteric feeding.
MeSH term(s)	Animals ; Disease Models, Animal ; Enteral Nutrition/methods ; Female ; Guinea Pigs ; Male
Language	Chinese
Publishing date	1989-12
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	1156818-5
ISSN	1000-7806
ISSN	1000-7806
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Article: [Impact of intensified maintenance therapy on the prognosis of children and adolescents with advanced lymphoblastic lymphoma].

Yang, K B / Sun, X F / Zhen, Z Z / Lu, S Y / Zhu, J / Sun, F F / Wang, J / Huang, J T / Chen, R R / Ye, L T / Liu, Y / You, Z Y

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

2017 Volume 38, Issue 9, Page(s) 778–783

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Antineoplastic Combined Chemotherapy Protocols ; Child ; Disease-Free Survival ; Humans ; Methotrexate ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Prognosis ; Retrospective Studies ; Treatment Outcome
Chemical Substances	Methotrexate (YL5FZ2Y5U1)
Language	Chinese
Publishing date	2017-10-26
Publishing country	China
Document type	Journal Article
ISSN	0253-2727
ISSN	0253-2727
DOI	10.3760/cma.j.issn.0253-2727.2017.09.009
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Article: [Age-related modification effect on the association between body mass index and the risk of hypertension: A Cohort Study on Chinese people living in the rural areas].

Zhang, D D / Liu, X J / Wang, B Y / Ren, Y C / Zhao, Y / Liu, F Y / Liu, D C / Cheng, C / Chen, X / Liu, L L / Zhou, Q G / Xu, Q H / Xiong, Y H / Liu, J L / You, Z Y / Zhang, M / Hu, D S

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

2018 Volume 39, Issue 6, Page(s) 765–769

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Adolescent ; Age Factors ; Aged ; Asian Continental Ancestry Group/statistics & numerical data ; Body Mass Index ; Cohort Studies ; Female ; Follow-Up Studies ; Humans ; Hypertension/epidemiology ; Hypertension/ethnology ; Incidence ; Logistic Models ; Male ; Middle Aged ; Risk Factors ; Rural Population
Language	Chinese
Publishing date	2018-06-12
Publishing country	China
Document type	Journal Article
ZDB-ID	645026-x
ISSN	0254-6450
ISSN	0254-6450
DOI	10.3760/cma.j.issn.0254-6450.2018.06.014
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Article: [Pathological study on the renal toxicity of chelates used in the treatment of heavy metal poisoning].

Sun, S Q / You, Z Y

Zhonghua bing li xue za zhi = Chinese journal of pathology

1987 Volume 16, Issue 3, Page(s) 202–5, 38

MeSH term(s)	Animals ; Chelating Agents/adverse effects ; Dogs ; Female ; Haplorhini ; Kidney/drug effects ; Kidney Cortex Necrosis/chemically induced ; Kidney Cortex Necrosis/pathology ; Male ; Pentetic Acid/adverse effects ; Rats ; Rats, Inbred Strains ; Time Factors ; Uranium/poisoning ; Uranyl Nitrate
Chemical Substances	Chelating Agents ; Uranyl Nitrate (0C0WI17JYF) ; Uranium (4OC371KSTK) ; Pentetic Acid (7A314HQM0I)
Language	Chinese
Publishing date	1987-09
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	784533-9
ISSN	0529-5807
ISSN	0529-5807
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Article: [Preserving intestinal function after severe burn injury].

Shao, H / You, Z Y / Wang, S L

Zhonghua yi xue za zhi

1994 Volume 74, Issue 2, Page(s) 80–2, 126

Abstract: To study the changes of the bowel-barrier function and its preservation, we developed a new animal model. A specially bred miniswine (Guizhou species) was used with multiple catheterizations for sampling different blood from portal, inferior mesenteric ... ...

Abstract	To study the changes of the bowel-barrier function and its preservation, we developed a new animal model. A specially bred miniswine (Guizhou species) was used with multiple catheterizations for sampling different blood from portal, inferior mesenteric as will as jugular (central) veins. The animals were sustained with 30% III burns of TBSA 7 days after catheterization and divided randomly into early feeding (EF) group, given a complete diet beginning from 2 hours postburn (n = 6) and delayed feeding (DF) group, given the same diet initiating on 4 days postburn (n = 6). The results indicated that the bowel-barrier function was weakened significantly early postburn so that the translocation of both endotoxin and bacteria from the gut to portal vein was evidently increased. However, improving the intestinal mucosa ischemia, preserving mucosal mass and maintaining bowel-microecological balance through early enteral feeding, as revealed in this study, could enhance the barrier function, and the translocation of bacteria and endotoxin would be thus decreased to some extent.
MeSH term(s)	Animals ; Burns/diet therapy ; Burns/physiopathology ; DNA/metabolism ; Endotoxins/blood ; Enteral Nutrition ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/physiopathology ; Male ; RNA/metabolism ; Random Allocation ; Swine ; Swine, Miniature ; Time Factors
Chemical Substances	Endotoxins ; RNA (63231-63-0) ; DNA (9007-49-2)
Language	Chinese
Publishing date	1994-02
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	132513-9
ISSN	0376-2491
ISSN	0376-2491
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Article: [Severe burn injury: glucose absorption and early enteral nutrition].

Shao, H / You, Z Y / Wang, S L

Zhonghua wai ke za zhi [Chinese journal of surgery

1994 Volume 32, Issue 3, Page(s) 183–186

Abstract: We investigated the changes of glucose absorption and the effect of early enteral nutrition after severe burn injury. A new animal model was developed with a specially bred miniswine (Gui Zhou species) to which multiple catheterizations were applied for ... ...

Abstract	We investigated the changes of glucose absorption and the effect of early enteral nutrition after severe burn injury. A new animal model was developed with a specially bred miniswine (Gui Zhou species) to which multiple catheterizations were applied for sampling different blood from the portal, inferior mesenteric as well as jugular (central) veins. The animals were sustained with 30% III burns of TBSA 7 days after the catheterizations and divided randomly into early feeding (EF) group, given a complete diet beginning from 2 hours postburn, and delayed feeding (DF) group, given the same diet on 4 days postburn. After burn injury, glucose absorption was significantly decreased, but the absorption was much lower in group DF than that in group EF. However, the intestinal ability of absorbing nutrients was not attenuated greatly, and the reduction of portal blood flow was attributed to the decrease of absorption of nutrients. Early enteral feeding can increase portal blood flow obviously.
MeSH term(s)	Animals ; Blood Circulation ; Burns/physiopathology ; Glucose/pharmacokinetics ; Intestinal Absorption ; Male ; Portal Vein/physiopathology ; Random Allocation ; Swine ; Swine, Miniature ; Time Factors
Chemical Substances	Glucose (IY9XDZ35W2)
Language	Chinese
Publishing date	1994-03
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	604573-x
ISSN	0529-5815
ISSN	0529-5815
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Zs.B 2469: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 218: Show issues

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Article: Effect on polyomavirus T-antigen function of mutations in a conserved leucine-rich segment of the DnaJ domain.

Li, H / Söderbärg, K / Houshmand, H / You, Z Y / Magnusson, G

Journal of virology

2001 Volume 75, Issue 5, Page(s) 2253–2261

Abstract: The N-terminal part of the mouse polyomavirus T antigens contains a highly conserved segment (-LLELLKL-), including amino acid residues 13 to 19. The sequence motif is predicted to form alpha helix I in the DnaJ domain of the T antigens. Four mutants ... ...

Abstract	The N-terminal part of the mouse polyomavirus T antigens contains a highly conserved segment (-LLELLKL-), including amino acid residues 13 to 19. The sequence motif is predicted to form alpha helix I in the DnaJ domain of the T antigens. Four mutants with conservative substitutions of amino acid residues 13 and 14 were constructed. Of the four substitutions, L13M, L13I, L13V, and L14V, only L13V resulted in a phenotypic change. In transfected mouse cells, L13V large T antigen showed a more than 100-fold-reduced viral DNA synthesis. The viral replication could not be rescued by cotransfection of the cells with DNA expressing small t antigen or a large T antigen truncated at the C terminus that would compensate for a defect in host cell stimulation. In contrast to the effect on DNA replication, the L13V substitution in large T antigen did not prevent complex formation with Hsc70 and the Rb protein. Also, the activity of the protein in transactivation of transcription from the adenovirus E2 promoter was unimpaired, showing that the transcription factor E2F was released from pRb. The L13V substitution also caused a defect in small t antigen. However, this phenotypic change was due to protein instability. In contrast, middle T antigen with the L13V substitution remained stable and functional in cellular transformation. Together, the data show that the effect of the L13V substitution did not abrogate the Hsc70 interaction of the DnaJ domain. However, it is possible that the substitution of amino acid residue 13 affected specific DnaJ functions of large T antigen.
MeSH term(s)	3T3 Cells ; Amino Acid Motifs ; Animals ; Antigens, Polyomavirus Transforming/chemistry ; Antigens, Polyomavirus Transforming/genetics ; Antigens, Polyomavirus Transforming/metabolism ; Antigens, Viral, Tumor ; Cell Line ; DNA Replication ; DNA, Viral/biosynthesis ; HSC70 Heat-Shock Proteins ; HSP40 Heat-Shock Proteins ; HSP70 Heat-Shock Proteins/metabolism ; Heat-Shock Proteins/chemistry ; Heat-Shock Proteins/genetics ; Leucine/chemistry ; Mice ; Mutation ; Plasmids/genetics ; Polyomavirus/immunology ; Polyomavirus/physiology ; Rats ; Retinoblastoma Protein/metabolism ; Transcriptional Activation ; Transfection
Chemical Substances	Antigens, Polyomavirus Transforming ; Antigens, Viral, Tumor ; DNA, Viral ; HSC70 Heat-Shock Proteins ; HSP40 Heat-Shock Proteins ; HSP70 Heat-Shock Proteins ; Heat-Shock Proteins ; Hspa8 protein, mouse ; Hspa8 protein, rat ; Retinoblastoma Protein ; Leucine (GMW67QNF9C)
Language	English
Publishing date	2001-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80174-4
ISSN	1098-5514 ; 0022-538X
ISSN (online)	1098-5514
ISSN	0022-538X
DOI	10.1128/JVI.75.5.2253-2261.2001
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Article: Existence of memory in ion channels.

Fang, J Q / Ni, T Y / You, Z Y / Fan, J / Guan, Y Y

Zhongguo yao li xue bao = Acta pharmacologica Sinica

1995 Volume 16, Issue 3, Page(s) 213–217

Abstract: Aim: To explore the existence of memory in Ca(2+)-dependent K+ channels of cultured aortic smooth muscle cells (ASMC) and voltage-dependent K+ channels of clonal pheochromocytoma (PC12) cells.: Methods: Calculating the sample auto-correlation ... ...

Abstract	Aim: To explore the existence of memory in Ca(2+)-dependent K+ channels of cultured aortic smooth muscle cells (ASMC) and voltage-dependent K+ channels of clonal pheochromocytoma (PC12) cells. Methods: Calculating the sample auto-correlation functions based on the digitized signals or the 0-1 series corresponding to closing and opening of the channels after routine evaluation, rather than the sequence of sojourn times. Results: The sample auto-correlations showed a decreasing trend with elapse of time, stable to repeated observations under the same conditions and sensitive to treatments. Conclusion: The attribute of memory exists in some single channels as an intrinsic feature of them, independent of any extrinsic assumptions on missing observations due to limited time resolution.
MeSH term(s)	Animals ; Aorta, Thoracic/pathology ; Cells, Cultured ; Clone Cells ; Hypertension/physiopathology ; Muscle, Smooth, Vascular/pathology ; Pheochromocytoma/pathology ; Potassium Channels/physiology ; Rats ; Rats, Inbred SHR ; Rats, Inbred WKY ; Signal Transduction ; Tumor Cells, Cultured
Chemical Substances	Potassium Channels
Language	English
Publishing date	1995-05
Publishing country	China
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	605592-8
ISSN	0253-9756
ISSN	0253-9756
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Article ; Online: Measurements of All-Particle Energy Spectrum and Mean Logarithmic Mass of Cosmic Rays from 0.3 to 30 PeV with LHAASO-KM2A.

Cao, Zhen / Aharonian, F / Axikegu / Bai, Y X / Bao, Y W / Bastieri, D / Bi, X J / Bi, Y J / Bian, W / Bukevich, A V / Cao, Q / Cao, W Y / Cao, Zhe / Chang, J / Chang, J F / Chen, A M / Chen, E S / Chen, H X / Chen, Liang /

Chen, Lin / Chen, Long / Chen, M J / Chen, M L / Chen, Q H / Chen, S / Chen, S H / Chen, S Z / Chen, T L / Chen, Y / Cheng, N / Cheng, Y D / Cui, M Y / Cui, S W / Cui, X H / Cui, Y D / Dai, B Z / Dai, H L / Dai, Z G / Danzengluobu / Dong, X Q / Duan, K K / Fan, J H / Fan, Y Z / Fang, J / Fang, J H / Fang, K / Feng, C F / Feng, H / Feng, L / Feng, S H / Feng, X T / Feng, Y / Feng, Y L / Gabici, S / Gao, B / Gao, C D / Gao, Q / Gao, W / Gao, W K / Ge, M M / Geng, L S / Giacinti, G / Gong, G H / Gou, Q B / Gu, M H / Guo, F L / Guo, X L / Guo, Y Q / Guo, Y Y / Han, Y A / Hasan, M / He, H H / He, H N / He, J Y / He, Y / Hor, Y K / Hou, B W / Hou, C / Hou, X / Hu, H B / Hu, Q / Hu, S C / Huang, D H / Huang, T Q / Huang, W J / Huang, X T / Huang, X Y / Huang, Y / Ji, X L / Jia, H Y / Jia, K / Jiang, K / Jiang, X W / Jiang, Z J / Jin, M / Kang, M M / Karpikov, I / Kuleshov, D / Kurinov, K / Li, B B / Li, C M / Li, Cheng / Li, Cong / Li, D / Li, F / Li, H B / Li, H C / Li, Jian / Li, Jie / Li, K / Li, S D / Li, W L / Li, X R / Li, Xin / Li, Y Z / Li, Zhe / Li, Zhuo / Liang, E W / Liang, Y F / Lin, S J / Liu, B / Liu, C / Liu, D / Liu, D B / Liu, H / Liu, H D / Liu, J / Liu, J L / Liu, M Y / Liu, R Y / Liu, S M / Liu, W / Liu, Y / Liu, Y N / Luo, Q / Luo, Y / Lv, H K / Ma, B Q / Ma, L L / Ma, X H / Mao, J R / Min, Z / Mitthumsiri, W / Mu, H J / Nan, Y C / Neronov, A / Ou, L J / Pattarakijwanich, P / Pei, Z Y / Qi, J C / Qi, M Y / Qiao, B Q / Qin, J J / Raza, A / Ruffolo, D / Sáiz, A / Saeed, M / Semikoz, D / Shao, L / Shchegolev, O / Sheng, X D / Shu, F W / Song, H C / Stenkin, Yu V / Stepanov, V / Su, Y / Sun, D X / Sun, Q N / Sun, X N / Sun, Z B / Takata, J / Tam, P H T / Tang, Q W / Tang, R / Tang, Z B / Tian, W W / Wang, C / Wang, C B / Wang, G W / Wang, H G / Wang, H H / Wang, J C / Wang, Kai / Wang, L P / Wang, L Y / Wang, P H / Wang, R / Wang, W / Wang, X G / Wang, X Y / Wang, Y / Wang, Y D / Wang, Y J / Wang, Z H / Wang, Z X / Wang, Zhen / Wang, Zheng / Wei, D M / Wei, J J / Wei, Y J / Wen, T / Wu, C Y / Wu, H R / Wu, Q W / Wu, S / Wu, X F / Wu, Y S / Xi, S Q / Xia, J / Xiang, G M / Xiao, D X / Xiao, G / Xin, Y L / Xing, Y / Xiong, D R / Xiong, Z / Xu, D L / Xu, R F / Xu, R X / Xu, W L / Xue, L / Yan, D H / Yan, J Z / Yan, T / Yang, C W / Yang, C Y / Yang, F / Yang, F F / Yang, L L / Yang, M J / Yang, R Z / Yang, W X / Yao, Y H / Yao, Z G / Yin, L Q / Yin, N / You, X H / You, Z Y / Yu, Y H / Yuan, Q / Yue, H / Zeng, H D / Zeng, T X / Zeng, W / Zha, M / Zhang, B B / Zhang, F / Zhang, H / Zhang, H M / Zhang, H Y / Zhang, J L / Zhang, Li / Zhang, P F / Zhang, P P / Zhang, R / Zhang, S B / Zhang, S R / Zhang, S S / Zhang, X / Zhang, X P / Zhang, Y F / Zhang, Yi / Zhang, Yong / Zhao, B / Zhao, J / Zhao, L / Zhao, L Z / Zhao, S P / Zhao, X H / Zheng, F / Zhong, W J / Zhou, B / Zhou, H / Zhou, J N / Zhou, M / Zhou, P / Zhou, R / Zhou, X X / Zhu, B Y / Zhu, C G / Zhu, F R / Zhu, H / Zhu, K J / Zou, Y C / Zuo, X

Physical review letters

2024 Volume 132, Issue 13, Page(s) 131002

Abstract: We present the measurements of all-particle energy spectrum and mean logarithmic mass of cosmic rays in the energy range of 0.3-30 PeV using data collected from LHAASO-KM2A between September 2021 and December 2022, which is based on a nearly composition- ... ...

Abstract	We present the measurements of all-particle energy spectrum and mean logarithmic mass of cosmic rays in the energy range of 0.3-30 PeV using data collected from LHAASO-KM2A between September 2021 and December 2022, which is based on a nearly composition-independent energy reconstruction method, achieving unprecedented accuracy. Our analysis reveals the position of the knee at 3.67±0.05±0.15 PeV. Below the knee, the spectral index is found to be -2.7413±0.0004±0.0050, while above the knee, it is -3.128±0.005±0.027, with the sharpness of the transition measured with a statistical error of 2%. The mean logarithmic mass of cosmic rays is almost heavier than helium in the whole measured energy range. It decreases from 1.7 at 0.3 PeV to 1.3 at 3 PeV, representing a 24% decline following a power law with an index of -0.1200±0.0003±0.0341. This is equivalent to an increase in abundance of light components. Above the knee, the mean logarithmic mass exhibits a power law trend towards heavier components, which is reversal to the behavior observed in the all-particle energy spectrum. Additionally, the knee position and the change in power-law index are approximately the same. These findings suggest that the knee observed in the all-particle spectrum corresponds to the knee of the light component, rather than the medium-heavy components.
Language	English
Publishing date	2024-04-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.132.131002
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