LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 311

Search options

  1. Article ; Online: A portable feedback-controlled pump for monitoring eye outflow facility in conscious rats

    Youssef Mohamed / Christopher L. Passaglia

    PLoS ONE, Vol 18, Iss

    2023  Volume 1

    Abstract: Intraocular pressure (IOP) is heavily influenced by the resistance of trabecular outflow pathways through which most of the aqueous humor produced by the eye continuously drains. The standard method of quantifying outflow resistance and other aspects of ... ...

    Abstract Intraocular pressure (IOP) is heavily influenced by the resistance of trabecular outflow pathways through which most of the aqueous humor produced by the eye continuously drains. The standard method of quantifying outflow resistance and other aspects of ocular fluid dynamics is eye cannulation, which allows for direct measurement and manipulation of IOP and flow in animal models. Since the method is invasive, indirect techniques that are slower and less accurate must be used for chronological studies. A novel technology is introduced that can autonomously measure outflow facility in conscious rats multiple times a day. A smart portable micropump infuses fluid into the eye through a permanently-implanted cannula and dynamically adjusts flow rate using a unique proportional feedback algorithm that sets IOP to a target level, even though IOP fluctuates erratically in awake free-moving animals. Pressure-flow data collected by the system from anesthetized rats were validated against intraocular recordings with commercial pressure and flow sensors. System and sensor estimates of outflow facility were indistinguishable, averaging 23 ± 3 nl·min-1·mmHg-1 across animals (n = 11). Pressure-flow data were then collected round-the-clock for several days from conscious rats, while outflow facility was measured every few hours. A significant diurnal facility rhythm was observed in every animal (n = 4), with mean daytime level of 22 ± 10 nl·min-1·mmHg-1 and mean nighttime level of 15 ± 7 nl·min-1·mmHg-1. The rhythm correlated with diurnal changes in IOP and likely contributed prominently to those changes based on the day-night swing in facility magnitude. Hence, the portable smart pump offers a unique tool for repeated long-term monitoring of outflow facility and other possible parameters of ocular health. It could also be useful in animal glaucoma studies for reversibly inducing acute or chronic ocular hypertension without explicitly damaging trabecular outflow pathways.
    Keywords Medicine ; R ; Science ; Q
    Subject code 630
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  2. Article ; Online: Simulation of gravity- and pump-driven perfusion techniques for measuring outflow facility of ex vivo and in vivo eyes.

    Youssef Mohamed / Christopher L Passaglia

    PLoS ONE, Vol 18, Iss 11, p e

    2023  Volume 0294607

    Abstract: Aqueous humor dynamics are commonly assessed by infusing fluid into the eye and measuring intraocular pressure (IOP). From the pressure-flow relationship, conventional outflow facility is estimated to study glaucomatous processes that lower facility or ... ...

    Abstract Aqueous humor dynamics are commonly assessed by infusing fluid into the eye and measuring intraocular pressure (IOP). From the pressure-flow relationship, conventional outflow facility is estimated to study glaucomatous processes that lower facility or identify therapeutics that enhance facility in hopes of restoring healthy IOP levels. The relative merits and limitations of constant flow (CF), gravity-driven constant pressure (CPg), and pump-driven constant pressure (CPp) infusion techniques were explored via simulations of a lumped parameter viscoelastic model of the eye. Model parameter values were based on published perfusion system properties and outflow facility data from rodents. Step increases in pressure or flow were simulated without and with IOP noise recorded from enucleated eyes, anesthetized animals, and conscious animals. Steady-state response levels were determined using published window and ratio criteria. Model simulations show that all perfusion techniques estimate facility accurately and that ocular fluid dynamics set a hard limit on how fast measurements can be taken. This limit can be approached with CPg and CPp systems by increasing their gain but not with CF systems, which invariably take longest to settle. Facility experiment duration is further lengthened by inclusion of IOP noise, and data filtering is needed for steady-state detection with in vivo noise. The ratio criterion was particularly affected because noise in the flow data is amplified by the higher gain of CPg and CPp systems. A recursive regression method is introduced, which can ignore large transient IOP fluctuations that interfere with steady-state detection by fitting incoming data to the viscoelastic eye model. The fitting method greatly speeds up data collection without loss of accuracy, which could enable outflow facility measurements in conscious animals. The model may be generalized to study response dynamics to fluid infusion in other viscoelastic compartments of the body and model insights extended to optimize ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 600
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  3. Article ; Online: Diagnostic reliability and accuracy of the hydraulic contrast lift protocol in the radiographic detection of sinus lift and perforation: ex vivo randomized split-mouth study in an ovine model.

    Youssef, Mohamed A / von Krockow, Nadine / Pfaff, Jacqueline A

    BDJ open

    2024  Volume 10, Issue 1, Page(s) 6

    Abstract: Objectives: Assessing the diagnostic reliability, validity, and accuracy of the hydraulic contrast lift protocol during transcrestal sinus floor elevation in detecting the lift and perforation of the sinus membrane before graft material application and ... ...

    Abstract Objectives: Assessing the diagnostic reliability, validity, and accuracy of the hydraulic contrast lift protocol during transcrestal sinus floor elevation in detecting the lift and perforation of the sinus membrane before graft material application and assessing the effect of its use on the operator's diagnostic confidence.
    Material and methods: A single-blind randomized split-mouth study on fresh refrigerated sheep heads. The first intervention consisted of injecting 0.5 ml iodinated contrast medium on the test side and 0.5 ml saline on the control side. In the second intervention artificial sinus membrane perforations were created followed by injecting 0.5 ml iodinated contrast medium on the test side and 0.5 ml saline on the control side. Intraoperative periapical radiographs were taken for both interventions. The resulting 40 radiographs were assessed by 10 examiners to provide interpretations and confidence ratings. The primary endpoints were diagnostic reliability, validity, accuracy, and perceived diagnostic confidence.
    Results: In the hydraulic contrast lift protocol, the detection rate was 99% for sinus elevations and 98% for perforations, the saline protocol yielded a detection rate of 28% and 20% respectively. The hydraulic contrast lift protocol demonstrated a high level of inter-rater agreement for the diagnosis of elevations (p < 0.001) and perforations (p < 0.001), strong diagnostic validity for the diagnosis of elevations (p < 0.001) and perforations (p < 0.001), high sensitivity and specificity (p < 0.001) and higher mean diagnostic confidence ratings for both interventions when compared to the saline protocol (p < 0.001). The difference between the predicted probability for correct diagnosis of the hydraulic contrast lift protocol and the saline protocol was significant (p < 0.001) for the detection of both elevations and perforations.
    Conclusion: Following the hydraulic contrast lift protocol, the use of a radiographic contrast medium can reliably confirm sinus membrane lift and detect perforation during transcrestal sinus floor elevation prior to bone graft application in addition to improving the diagnostic confidence of the operator while relying on periapical radiographs.
    Language English
    Publishing date 2024-01-31
    Publishing country England
    Document type Journal Article
    ISSN 2056-807X
    ISSN (online) 2056-807X
    DOI 10.1038/s41405-024-00188-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: A Comparative Electromyographic Analysis of Masticatory Muscles Between Skeletal Class II and Skeletal Class I Malocclusion: A Cross-Sectional Study on a Syrian Population.

    Saker, Ali A / Hajeer, Mohammad Y / Youssef, Mohamed

    Cureus

    2024  Volume 16, Issue 2, Page(s) e53960

    Abstract: Objectives: This study aimed to investigate whether there was a difference in the muscular activity of the masticatory muscles between patients with skeletal Class II and skeletal Class I malocclusion.: Materials and methods: A cross-sectional study ... ...

    Abstract Objectives: This study aimed to investigate whether there was a difference in the muscular activity of the masticatory muscles between patients with skeletal Class II and skeletal Class I malocclusion.
    Materials and methods: A cross-sectional study was conducted using a sample of 56 selected patients referred to the Department of Orthodontics and Dentofacial Orthodontics, Faculty of Dentistry at the University of Damascus, Damascus, Syria. An electromyographic device measured the myoelectric activity of the perioral muscles on patients in the two created groups: the skeletal Class I malocclusion group (n=28 patients) and the skeletal Class II malocclusion group (n=28 patients).
    Results: The study found a similarity in the muscular activity between the right and left sides within the same group, without significant differences between both sides for each muscle (P>0.05). The Class II group had significantly greater activity in the buccinator and digastric muscles than the Class I group (p<0.05). On the other hand, the Class I group had significantly greater activity in the orbicularis and mentalis muscles than the Class II group (P<0.05).
    Conclusion: Patients with skeletal Class II malocclusion and skeletal Class I showed differences in muscular activity. The buccinator and digastric muscles were more active in skeletal Class II patients, while orbicularis oris and mentalis were less active. The temporalis and masseter muscles showed similar activity in both groups.
    Language English
    Publishing date 2024-02-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.53960
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Book ; Online: Fusion of Single and Integral Multispectral Aerial Images

    Youssef, Mohamed / Bimber, Oliver

    2023  

    Abstract: A novel hybrid (model- and learning-based) architecture is presented for fusing the most significant features from conventional aerial images with the ones from integral aerial images that are the result of synthetic aperture sensing for removing ... ...

    Abstract A novel hybrid (model- and learning-based) architecture is presented for fusing the most significant features from conventional aerial images with the ones from integral aerial images that are the result of synthetic aperture sensing for removing occlusion. It combines the environment's spatial references with features of unoccluded targets that would normally be hidden by dense vegetation. Our method out-beats state-of-the-art two-channel and multi-channel fusion approaches visually and quantitatively in common metrics, such as mutual information, visual information fidelity, and peak signal-to-noise ratio. The proposed model does not require manually tuned parameters, can be extended to an arbitrary number and combinations of spectral channels, and is reconfigurable for addressing different use cases.
    Keywords Electrical Engineering and Systems Science - Image and Video Processing ; Computer Science - Computer Vision and Pattern Recognition
    Publishing date 2023-11-29
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  6. Article ; Online: Application of geophysical techniques for shallow groundwater investigation using 1D-lateral constrained and 2D inversions in Ras Gara area, southwestern Sinai, Egypt

    Genedi, Mohamed A. / Youssef, Mohamed A. S.

    Environ Earth Sci. 2023 Mar., v. 82, no. 5 p.120-120

    2023  

    Abstract: There is an urgent need for greater water resources to support sustainable development in Ras Gara area of southwestern Sinai. Determining the water-bearing zones of the shallow Quaternary aquifer of the Araba Formation in the study region is therefore ... ...

    Abstract There is an urgent need for greater water resources to support sustainable development in Ras Gara area of southwestern Sinai. Determining the water-bearing zones of the shallow Quaternary aquifer of the Araba Formation in the study region is therefore the main objective of the research. This will be done by using a variety of geophysical techniques, such as DC resistivity sounding and shallow seismic refraction surveys. Using the Schlumberger array (max. AB = 1200 m), the DC data were gathered at 27 VES locations along five primary profiles. At the same locations, 27 spreads totaling 115 m in length of seismic data were also performed. One-dimensional laterally constrained (1D-LCI) inversion is only applied to the DC data in order to generate a best-fit model, whereas 2D inversion is applied to other datasets. The area is divided up into five geo-electrical layers based on the results of 1D-LCI inversion of DC data, and the aquifer is classified into fresh (third layer) and saline bearing-zones (fourth layer). The resistivity values of the fresh-zone range from 8.7 to 26.7 Ω.m, with only low values (5–7.5 Ω.m) found at some VES sites, while the resistivity values of the saline-zone range between 0.9 and 3 Ω.m, except for (14.4 Ω.m) at VES-04. At depths of (2.4–15.6 m) and (8.7–28.5 m) for the fresh and saline zones, respectively. In this region, the shallow low resistive (about 10–100 Ω.m) and intermediate high conductive (< 10 Ω.m) layers of the 2D-DC inverted model represent the fresh and saline zones of the aquifer, respectively. The basement rocks were represented by a deep, extremely high resistive layer that can reach 40,000 Ω.m. Three subsurface layers are identified from the results of the 2D inversion of seismic data (VP₁ = 400–1100 m.s⁻¹, VP₂ = 1200–1900 m.s⁻¹ and VP₃ = 2400–5400 m.s⁻¹). The saturated zone of this aquifer is represented by the second layer (depth, 3.7–20.5 m). The basement rocks are also reflected in the last layer of high velocity. The inversion results and the previously available hydro-geological map data show a good degree of concordance. In the eastern portion of the study area, additional water wells could be drilled for additional water resources.
    Keywords aquifers ; data collection ; geophysics ; groundwater ; models ; sustainable development ; Egypt
    Language English
    Dates of publication 2023-03
    Size p. 120.
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    ZDB-ID 2493699-6
    ISSN 1866-6299 ; 1866-6280
    ISSN (online) 1866-6299
    ISSN 1866-6280
    DOI 10.1007/s12665-023-10796-4
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  7. Article ; Online: Behavior and management of carp fish: A review.

    Mohammed, Hesham H / Ebrahim, Mohamed / Youssef, Mohamed I / Saleem, Al-Sadik Y / Abdelkhalek, Adel

    Open veterinary journal

    2024  Volume 14, Issue 1, Page(s) 1–11

    Abstract: Nowadays, fish production aims to achieve a continuous and immediate generation of top-quality animal protein from the finest sources. Moreover, the aquaculture industry holds a vital position in addressing the rising global appetite for fish and seafood ...

    Abstract Nowadays, fish production aims to achieve a continuous and immediate generation of top-quality animal protein from the finest sources. Moreover, the aquaculture industry holds a vital position in addressing the rising global appetite for fish and seafood products. In addition, it has played a substantial role in providing affordable animal protein in Egypt in recent years. Therefore, rapid development has occurred in the industrial aquaculture sector in Egypt to compensate for the decrease in red meat production. According to previous studies, Egypt occupied the first rank among African countries and the ninth position globally in the field of fish farming production. This achievement aimed to link up the disparity between fish production and consumption in Egypt. Carp, due to its economic importance in this industry, has expanded worldwide with more evident ecological influences. The carp fish belongs to the Cyprinidae family, which encompasses seven subfamilies, approximately 220 genera, and has been associated with around 20,000 documented species. Given the importance of carp with different species, this work reviews the management, behavior, and different rearing systems of some popular carp species in Egypt. Data search was done on PubMed, SCOPUS, Web of Science, and Google Scholar for the keywords including fish farming, carp fish, management, behavior, rearing systems, Egypt, Africa, and Worldwide. In Egypt, the output of carp is ranked second only to tilapia in aquaculture. A polyculture system is more often used in carp rearing, particularly when raising tilapia, to maximize growth rates, minimize feed conversion ratios, and reduce the amount of fat in the corpses. Furthermore, agro-ecologically valuable agriculture has been linked to integrated carp monoculture. Crop rising was the key to the successful development of pond aquaculture.
    MeSH term(s) Animals ; Carps ; Aquaculture ; Agriculture ; Seafood ; Egypt
    Language English
    Publishing date 2024-01-31
    Publishing country Libya
    Document type Journal Article ; Review
    ZDB-ID 2651664-0
    ISSN 2218-6050 ; 2218-6050
    ISSN (online) 2218-6050
    ISSN 2218-6050
    DOI 10.5455/OVJ.2024.v14.i1.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article: A Comparison Between Skeletal Class II and Class III Malocclusion Patients in Terms of the Masticatory Muscles' Activity: A Cross-Sectional Study.

    Saker, Ali A / Mousa, Mudar Mohammad / Hajeer, Mohammad Y / Haddad, Ibrahim / Alhaffar, Jacqueline Bashar / Youssef, Mohamed

    Cureus

    2024  Volume 16, Issue 5, Page(s) e59861

    Abstract: Background This study aimed to determine if individuals with skeletal Class II and skeletal Class III malocclusions had different levels of masticatory muscle activity. Materials and methods This cross-sectional study, conducted at the University of ... ...

    Abstract Background This study aimed to determine if individuals with skeletal Class II and skeletal Class III malocclusions had different levels of masticatory muscle activity. Materials and methods This cross-sectional study, conducted at the University of Damascus, investigated the myoelectric activity of perioral muscles in patients with Class II and III malocclusions. The sample size of 60 patients was determined according to a prior sample size calculation. Patients were selected based on specific inclusion and exclusion criteria and divided into Class II and III groups. Electromyography was used to monitor the activity of various muscles, including the temporalis, masseter, orbicularis oris, buccinator, mentalis, and digastric muscles. Results The study found similar muscle activity within the same group in the temporalis, masseter, buccinator, digastric, and orbicularis oris muscles. No significant differences were observed between the Class II and III groups for several oral and perioral muscles (P > 0.05). However, the mean activity of the digastric muscle was significantly greater in the Class II group (P < 0.05), whereas the mean activity of the mentalis muscle was smaller in the Class II group (P < 0.05). Conclusions Perioral muscles influence facial complex development and jaw relationship, affecting orthodontic treatment. Digastric muscle activity is greater in Class II patients, while mental muscle activity is smaller in Class III patients. Further studies are needed for older age groups and other skeletal malocclusion types.
    Language English
    Publishing date 2024-05-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.59861
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Order differences to enhance the delineation of rock units boundaries by using aerospectrometric data of Wadi Al Mushash area, Central Eastern Desert, Egypt: A new approach.

    Youssef, Mohamed A S

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

    2019  Volume 155, Page(s) 108938

    Abstract: The present work utilizes airborne gamma-ray spectrometric data, in a trial to refine the surface geological mapping of sedimentary rocks at Wadi Al Mushash, Central Eastern Desert of Egypt. The acquired aerospectrometric data were supported by the ... ...

    Abstract The present work utilizes airborne gamma-ray spectrometric data, in a trial to refine the surface geological mapping of sedimentary rocks at Wadi Al Mushash, Central Eastern Desert of Egypt. The acquired aerospectrometric data were supported by the surface geology concerning the study area. This area is mainly covered by sedimentary rocks of Tertiary to upper Cretaceous as Nubian Sandstone Formations (Quseir Clastics and Tarif Sandstone), Duwi Phosphates Formation, Dakhla Shale Formation, Esna Shale Formation, Tarawan Formation, Thebes Formation, and Quaternary deposits. High-resolution airborne gamma-ray spectrometry can be very helpful in mapping the surface geology. The method provides estimation of the apparent surface concentrations of the most common naturally occurring radioactive elements, such as potassium (K), equivalent uranium (eU) and equivalent thorium (eTh). This work is based on the assumption that, the absolute and relative concentrations of these radioelements vary measurably and significantly with lithology. The composite image technique is used to display and simulate three parameters of the radioelements concentrations. The technique offered much in terms of lithologic discrimination, based on color differences and showed efficiency in defining areas, where different lithofacies occur within areas mapped as one continuous lithology. The Differences technique is used to delineate contacts of the rock units and the mainly structures of the study area. It is based mainly on varying in change of concentration of successive total count measurements within each line in the study area. Then, a suitable difference order is selected and matched to original measured line. Moreover, plotting the suitable order as grid and applied grid peaks on this grid. Then, these ridge grid peaks are symbolized over surface geological information and prepared radioelement composite map. This provides more detail about the surface geology, and addition more contacts occurred within original rock units. These subdivisions of rock units may be related to one formation that consists of more than one member having a different composition.
    Language English
    Publishing date 2019-10-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1142596-9
    ISSN 1872-9800 ; 0883-2889 ; 0969-8043
    ISSN (online) 1872-9800
    ISSN 0883-2889 ; 0969-8043
    DOI 10.1016/j.apradiso.2019.108938
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: Development and application of DRAINMOD model for simulating crop yield and water conservation benefits of drainage water recycling

    Moursi, Hossam / Youssef, Mohamed A. / Chescheir, George M.

    Agricultural water management. 2022 May 31, v. 266

    2022  

    Abstract: Drainage water recycling (DWR) is an emerging practice that has the potential to increase crop yield and improve water quality. DWR involves capturing and storing subsurface drainage water and surface runoff in ponds or reservoirs, and using this water ... ...

    Abstract Drainage water recycling (DWR) is an emerging practice that has the potential to increase crop yield and improve water quality. DWR involves capturing and storing subsurface drainage water and surface runoff in ponds or reservoirs, and using this water for supplemental irrigation during dry periods of the growing season. The main objective of this study was to enhance DRAINMOD model to simulate the hydrology and crop yield of DWR systems. The expanded model; named DRAINMOD-DWR, has a new module that conducts a water balance of the storage reservoir and simulates the interaction between the reservoir and the field, irrigated from and/or draining into the reservoir. The model predicts the long-term performance of DWR as affected by weather conditions, soil type, crop rotation, reservoir size, and irrigation and drainage management. Three performance metrics were defined based on model predictions to quantify irrigation, crop yield, and water capture benefits of DWR. To demonstrate the new features of the model, uncalibrated DRAINMOD-DWR was applied to a hypothetical DWR system with continuous corn using a 50-yr (1970–2019) weather record in Eastern North Carolina, U.S. Different reservoir sizes were simulated to demonstrate how the model can predict the effect of storage capacity on the system’s performance. The model predicted that a 3.0-m deep reservoir with a surface area of 4% of the field area would optimize corn yield for the simulated conditions. The model application clearly demonstrated the DRAINMOD-DWR model’s capability of optimizing the DWR system design to avoid under-sizing or over-sizing the storage reservoir, which reduces system’s performance and increases implementation cost. Research is needed to test DRAINMOD-DWR using field measured data, and to develop routines for simulating the fate and transport of nutrients and sediment in the storage reservoir, which would enable the model to predict the water quality benefits of DWR.
    Keywords DRAINMOD model ; corn ; crop rotation ; crop yield ; irrigation ; runoff ; sediments ; simulation models ; soil types ; subsurface drainage ; surface area ; systems engineering ; water conservation ; water quality ; weather ; North Carolina
    Language English
    Dates of publication 2022-0531
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 751144-9
    ISSN 1873-2283 ; 0378-3774
    ISSN (online) 1873-2283
    ISSN 0378-3774
    DOI 10.1016/j.agwat.2022.107592
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

To top