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  1. Article: A Formative History of Integrative Medicine in Hong Kong.

    Yu, Edwin Chau-Leung / Bian, Zhao-Xiang

    Chinese journal of integrative medicine

    2019  Volume 25, Issue 6, Page(s) 403–408

    MeSH term(s) Evidence-Based Medicine ; History, 21st Century ; Hong Kong ; Humans ; Integrative Medicine/economics ; Integrative Medicine/education ; Integrative Medicine/history ; Research
    Language English
    Publishing date 2019-06-25
    Publishing country China
    Document type Historical Article ; Journal Article
    ZDB-ID 2171254-2
    ISSN 1993-0402 ; 1672-0415
    ISSN (online) 1993-0402
    ISSN 1672-0415
    DOI 10.1007/s11655-019-3160-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5823: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Efficacy and Safety of Chinese Herbal Medicine on Treatment of Breast Cancer: A Meta-analysis of Randomized Controlled Trials.

    Ho, Venice Wing-Tung / Tan, Hor-Yue / Guo, Wei / Li, Sha / Wang, Ning / Meng, Wei / So, Tsz-Him / Yu, Edwin Chau-Leung / Feng, Yibin

    The American journal of Chinese medicine

    2021  Volume 49, Issue 7, Page(s) 1557–1575

    Abstract: Breast cancer is currently the most common cancer in women, and it accounts for 11.6% of all cancer diagnoses in 2018. Breast cancer patients frequently resort to alternative medicine in addition to conventional Western therapy. This study is to evaluate ...

    Abstract Breast cancer is currently the most common cancer in women, and it accounts for 11.6% of all cancer diagnoses in 2018. Breast cancer patients frequently resort to alternative medicine in addition to conventional Western therapy. This study is to evaluate clinical effectiveness of Chinese herbal medicine (CHM) on breast cancer by conducting meta-analyses on 81 randomized controlled trials (RCTs) with a total of 7215 subjects from eight databases. All RCTs compared patients using Western therapy alone and those using additional CHM therapy to evaluate the difference of primary (tumor response, mean time to progression (mTTP), overall survival (OS) and progression free survival (PFS)) and secondary outcome measures (tumor markers). Results showed that under the RECIST1.1 criteria, 52% patients with additional CHM therapy (67%, under WHO criteria) achieved either a complete response (CR) or a partial response (PR), compared to 38% patients with Western therapy alone (53%, under the WHO criteria). The risk ratio was 1.31 ([Formula: see text] < 0.00001, 95% CI = 1.15-1.50) for patients with CHM plus Western therapy and 1.25 ([Formula: see text] < 0.00001, 95% CI = 1.18-1.98) for those with Western therapy. Moreover, patients with complementary CHM therapy were associated with an mTTP of 2.79 months longer ([Formula: see text] < 0.00001) and an OS of 1.90 months longer ([Formula: see text] < 0.00001); they also had an increase in 3-year PFS ([Formula: see text]= 0.002), 2- ([Formula: see text]= 0.0002) and 5-year ([Formula: see text]= 0.006) OS rates. Therefore, complementary CHM therapy might demonstrate clinical benefits for breast cancer patients in terms of tumor response and survival. Clinical studies with further stratification of tumor stages and intervention types are highly warranted.
    MeSH term(s) Breast Neoplasms/drug therapy ; Drugs, Chinese Herbal/therapeutic use ; Humans ; Phytotherapy/methods ; Randomized Controlled Trials as Topic ; Treatment Outcome
    Chemical Substances Drugs, Chinese Herbal
    Language English
    Publishing date 2021-09-16
    Publishing country Singapore
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 193085-0
    ISSN 1793-6853 ; 0090-2942 ; 0192-415X
    ISSN (online) 1793-6853
    ISSN 0090-2942 ; 0192-415X
    DOI 10.1142/S0192415X21500737
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1110: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Chinese Herbal Medicine for Reducing Chemotherapy-Associated Side-Effects in Breast Cancer Patients: A Systematic Review and Meta-Analysis.

    Li, Sha / So, Tsz-Him / Tang, Guoyi / Tan, Hor-Yue / Wang, Ning / Ng, Bacon Fung Leung / Chan, Chris Kam Wa / Yu, Edwin Chau-Leung / Feng, Yibin

    Frontiers in oncology

    2020  Volume 10, Page(s) 599073

    Abstract: Background: Chemotherapy usually induces a variety of side-effects in cancer treatment as it cannot tell normal cells apart from cancer cells and kills both. Chinese herbal medicine (CHM) has been regarded as a potential effective intervention for ... ...

    Abstract Background: Chemotherapy usually induces a variety of side-effects in cancer treatment as it cannot tell normal cells apart from cancer cells and kills both. Chinese herbal medicine (CHM) has been regarded as a potential effective intervention for relieving the side-effects of chemotherapy in breast cancer patients.
    Objective: This study aims to conduct a comprehensive systematic review and meta-analysis to evaluate the efficacy of CHM as adjuvant therapy for reducing the chemotherapy-induced side-effects in the treatment of breast cancer.
    Methods: Main electronic databases were searched up to May 2020 for Randomized Controlled Trials (RCTs) evaluating the effect of CHM on breast cancer patients with chemotherapy. The PRISMA statement was adopted in this study and meta-analyses were performed.
    Results: The included studies showed unsatisfied quality. Results based on available literature indicated that the adjunctive use of CHM with chemotherapy may reduce the chemotherapeutic agents-associated adverse events, including nausea and vomiting, diarrhea, alopecia, myelosuppression, and impaired immune function.
    Conclusion: A confident conclusion could not be have due to the lack of large scale and high quality trials.
    Language English
    Publishing date 2020-12-09
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2020.599073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Would integrated Western and traditional Chinese medicine have more benefits for stroke rehabilitation? A systematic review and meta-analysis.

    Zhong, Linda Ld / Zheng, Ya / Lau, Alexander Y / Wong, Norman / Yao, Liang / Wu, Xingyao / Shao, Tengteng / Lu, Zhenxing / Li, Huijuan / Yuen, Chun Sum / Guo, Jianwen / Lo, Suzanne / Chau, Janita / Chan, Kam Wa / Ng, Bacon Fung Leung / Bian, Zhaoxiang / Yu, Edwin Chau-Leung

    Stroke and vascular neurology

    2021  Volume 7, Issue 1, Page(s) 77–85

    Abstract: Background: Stroke is a major cause of death or long-term disability worldwide. Many patients with stroke receive integrative therapy consisting of Western medicine (WM) and routine rehabilitation in conjunction with Chinese medicine (CM), such as ... ...

    Abstract Background: Stroke is a major cause of death or long-term disability worldwide. Many patients with stroke receive integrative therapy consisting of Western medicine (WM) and routine rehabilitation in conjunction with Chinese medicine (CM), such as acupuncture and Chinese herbal medicine. However, there is no available evidence on the effectiveness of the combined use of WM and CM interventions in stroke rehabilitation.
    Aims: The purpose of this meta-analysis is to evaluate the results of all individual studies to assess the combined use of CM and WM in stroke rehabilitation compared with WM only.
    Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines were followed. MEDLINE, EMBASE, Cochrane and China National Knowledge Infrastructure (CNKI) were searched. The included outcomes were dependency, motor function, depression and swallowing function. Subgroup analysis was performed, and publication bias was assessed using funnel plots.
    Summary of review: 58 studies and 6339 patients were included in the meta-analysis. Subgroup analysis revealed that combined therapy comprising both acupuncture and WM had a superior effect on improving dependency and swallowing function compared with standard WM therapy alone. Potential superiority of combined therapy comprising CM and WM in improving depression compared with standard WM therapy was also found.
    Conclusions: Our results indicate that the combined use of CM and WM could be more efficacious in stroke rehabilitation compared with the use of WM therapy alone. However, most studies were short in duration (2 to 4 weeks) and prone to different types of biases, which prevents making any conclusion regarding the long-term effects and raises concerns regarding true efficacy in context of high likelihood of Hawthorn bias. So, more randomised controlled trials with more rigorous design and longer duration of treatment and follow-up need to be conducted to compare WM alone versus WM and CM combined.
    Prospero registration number: CRD42020152050.
    MeSH term(s) Acupuncture Therapy/adverse effects ; Acupuncture Therapy/methods ; China ; Humans ; Medicine, Chinese Traditional ; Stroke/diagnosis ; Stroke/therapy ; Stroke Rehabilitation/adverse effects
    Language English
    Publishing date 2021-08-26
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Review ; Systematic Review
    ISSN 2059-8696
    ISSN (online) 2059-8696
    DOI 10.1136/svn-2020-000781
    Database MEDical Literature Analysis and Retrieval System OnLINE

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