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  1. Article ; Online: The research on the effect of temperature of electro-surgical unit to surgical smoke distribution in theatre-in vitro and simulation study.

    Yu, Hui

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0299369

    Abstract: In electro-surgery, surgical smoke was hazard to surgeons and patient in theatre. In order to institute effective countermeasures, quantifying of the effect of tip temperature of electro-surgical unit to surgical smoke distribution in theatre was studied. ...

    Abstract In electro-surgery, surgical smoke was hazard to surgeons and patient in theatre. In order to institute effective countermeasures, quantifying of the effect of tip temperature of electro-surgical unit to surgical smoke distribution in theatre was studied. The relation of tip temperature to power of electro-surgical unit through in vitro cutting experiment. Based on experiment data, the mathematical model was established to simulate the electro-surgery in laminar operation room. As the power of electro-surgical knife increased, the knife tip temperature increased. Total content of (CO, CO2, CH4, NH3) in waste gas and net flow rate of waste gas at outlet increased with the rising temperature of knife tip and formation rate of condensed tar droplets and non-viable particles also increased. Based on simulation, it was found that The maximum height of surgical smoke rising right above the incision of electro-surgical unit was increased with rising temperature of electro-surgical knife tip. There was a spread route of dispersed surgical smoke near the walls of theatre through natural convection. The polynomial fitting relationship was derived. As the tip temperature of knife increased from 200 to 500°C, maximum ascending height of surgical smoke right above the incision position of electro-surgical unit increased from 1.1 m to 1.45 m. When the tip temperature of electro-knife was more 400°C, the CO content in the surgeon's operating zone was more than 200 ppm, which would cause the surgeon's HbCO level increased. As the patient's tissue in the wound during operation was open, when the electro-knife of more than 400°C, the content of condensed tar droplets and in-viable particle was higher than 20 g/m3 and 12 g/m3 in the zone around patient's wound of open tissue, which should be hazard to health of patient.
    MeSH term(s) Humans ; Smoke/analysis ; Temperature ; Computer Simulation ; Models, Theoretical
    Chemical Substances Smoke
    Language English
    Publishing date 2024-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0299369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Realization of an inherent time crystal in a dissipative many-body system

    Yu-Hui Chen / Xiangdong Zhang

    Nature Communications, Vol 14, Iss 1, Pp 1-

    2023  Volume 7

    Abstract: Abstract Time crystals are many-body states that spontaneously break translation symmetry in time the way that ordinary crystals do in space. While experimental observations have confirmed the existence of discrete or continuous time crystals, these ... ...

    Abstract Abstract Time crystals are many-body states that spontaneously break translation symmetry in time the way that ordinary crystals do in space. While experimental observations have confirmed the existence of discrete or continuous time crystals, these realizations have relied on the utilization of periodic forces or effective modulation through cavity feedback. The original proposal for time crystals is that they would represent self-sustained motions without any external periodicity, but realizing such purely self-generated behavior has not yet been achieved. Here, we provide theoretical and experimental evidence that many-body interactions can give rise to an inherent time crystalline phase. Following a calculation that shows an ensemble of pumped four-level atoms can spontaneously break continuous time translation symmetry, we observe periodic motions in an erbium-doped solid. The inherent time crystal produced by our experiment is self-protected by many-body interactions and has a measured coherence time beyond that of individual erbium ions.
    Keywords Science ; Q
    Subject code 531
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: The complete chloroplast genome sequence of

    Guo, Yu-Hui

    Mitochondrial DNA. Part B, Resources

    2021  Volume 6, Issue 3, Page(s) 936–937

    Abstract: ... Prunus ... ...

    Abstract Prunus discadenia
    Language English
    Publishing date 2021-03-16
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2021.1888336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Observation of the Therapeutic Effect of Correcting Foot Varus on Improving Knee Hyperextension and Gait in Patients After Stroke.

    Yu, Hui-Xian

    Current neurovascular research

    2021  Volume 18, Issue 3, Page(s) 314–317

    Abstract: Objective: The present study aimed to observe the therapeutic effect of elastic bandages on improving knee hyperextension in patients with stroke after correcting the foot varus.: Methods: A total of 45 patients with stroke admitted to the hospital ... ...

    Abstract Objective: The present study aimed to observe the therapeutic effect of elastic bandages on improving knee hyperextension in patients with stroke after correcting the foot varus.
    Methods: A total of 45 patients with stroke admitted to the hospital from January to August 2019 were enrolled in the present prospective study. Elastic bandages were used to fix the affected foot in a mild valgus position. Before and after the intervention, the Noitom walking function evaluation system was adopted, and the Timed Up and Go (TUG) test and the 10-meter walking test were conducted. The gait speed, stride length, knee angle, and the number of knee hyperextensions >5° were selected as the results. The weight-bearing time of the affected leg was evaluated, and the changes in the control ability of the affected limb before and after the intervention were compared.
    Results: It was found that compared with before treatment, the time of knee hyperextension was significantly reduced after fixation with the elastic bandage, and the knee extension angle was significantly reduced (p < 0.05). After the treatment, the gait speed was significantly higher than before the treatment (p < 0.05), but there was no statistically significant difference in the stride length (p > 0.05). After the treatment, the time in the TUG test was significantly shorter than before the treatment (p < 0.05), together with an obvious increase in the weight-bearing time of the affected leg (p < 0.05).
    Conclusion: Correcting foot varus could improve the biomechanics of the lower limbs and improve the symptoms of knee hyperextension in patients with stroke, thereby improving the control ability of the affected limb and improving the walking function.
    MeSH term(s) Biomechanical Phenomena ; Gait ; Humans ; Lower Extremity ; Prospective Studies ; Stroke/complications ; Stroke/therapy ; Walking
    Language English
    Publishing date 2021-10-07
    Publishing country United Arab Emirates
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2296350-9
    ISSN 1875-5739 ; 1567-2026
    ISSN (online) 1875-5739
    ISSN 1567-2026
    DOI 10.2174/1567202618666210923150711
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Realization of an inherent time crystal in a dissipative many-body system.

    Chen, Yu-Hui / Zhang, Xiangdong

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 6161

    Abstract: Time crystals are many-body states that spontaneously break translation symmetry in time the way that ordinary crystals do in space. While experimental observations have confirmed the existence of discrete or continuous time crystals, these realizations ... ...

    Abstract Time crystals are many-body states that spontaneously break translation symmetry in time the way that ordinary crystals do in space. While experimental observations have confirmed the existence of discrete or continuous time crystals, these realizations have relied on the utilization of periodic forces or effective modulation through cavity feedback. The original proposal for time crystals is that they would represent self-sustained motions without any external periodicity, but realizing such purely self-generated behavior has not yet been achieved. Here, we provide theoretical and experimental evidence that many-body interactions can give rise to an inherent time crystalline phase. Following a calculation that shows an ensemble of pumped four-level atoms can spontaneously break continuous time translation symmetry, we observe periodic motions in an erbium-doped solid. The inherent time crystal produced by our experiment is self-protected by many-body interactions and has a measured coherence time beyond that of individual erbium ions.
    Language English
    Publishing date 2023-10-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-41905-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Educational Robotics for Developing Computational Thinking in Young Learners: A Systematic Review.

    Ching, Yu-Hui / Hsu, Yu-Chang

    TechTrends : for leaders in education & training

    2023  , Page(s) 1–12

    Abstract: Educational robotics has been adopted to create interactive and engaging learning environments to develop computational thinking (CT) in K-12 learners. This study systematically examined 22 peer-reviewed empirical research articles on the use of ... ...

    Abstract Educational robotics has been adopted to create interactive and engaging learning environments to develop computational thinking (CT) in K-12 learners. This study systematically examined 22 peer-reviewed empirical research articles on the use of educational robotics to develop CT in young learners (pre-kindergarten to 6th grade) published between 2012 and 2021. The findings revealed that using robotics activities to develop CT has mostly been studied in the formal education settings with the duration of robotics curricular activities ranging from 80 minutes to 24 hours. The five CT skills studied most often include Sequencing, Conditionals, Loops, Debugging, and Algorithmic Thinking. The different versions of LEGO Mindstorms are the most frequently adopted robotic kits in the examined studies. The most frequently adopted learning and instructional strategies in the robotics activities include collaborative learning, project-based learning, and embodied learning. This paper identified and discussed developmentally appropriated CT skills, robotics kits, and pedagogical approaches suitable for supporting CT development in young learners. The findings can guide educators and instructional designers for future robotics activity design and development endeavors. This paper also identified gaps in the current research and recommended directions for advancing research in adopting robotics to develop CT in young learners.
    Language English
    Publishing date 2023-04-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2144706-8
    ISSN 1559-7075 ; 8756-3894
    ISSN (online) 1559-7075
    ISSN 8756-3894
    DOI 10.1007/s11528-023-00841-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Directed Differentiation of Human iPSCs into Microglia-Like Cells Using Defined Transcription Factors.

    Chen, Shih-Wei / Wong, Yu-Hui

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2683, Page(s) 53–68

    Abstract: The generation of a homogeneous population of microglia from human induced pluripotent stem cells (hiPSCs) is crucial to modeling neurological disorders, as well as the carrying out of drug screening and toxicity testing. Here, we provide a stepwise ... ...

    Abstract The generation of a homogeneous population of microglia from human induced pluripotent stem cells (hiPSCs) is crucial to modeling neurological disorders, as well as the carrying out of drug screening and toxicity testing. Here, we provide a stepwise protocol for the simple, robust, and efficient differentiation of hiPSCs into microglia-like cells (iMGs) by overexpression of SPI1 and CEBPA. This protocol details hiPSC culture, lentivirus production, lentivirus delivery, and, finally, the differentiation and validation of the iMG cells.
    MeSH term(s) Humans ; Induced Pluripotent Stem Cells ; Transcription Factors ; Microglia ; Cell Differentiation/genetics ; Cells, Cultured
    Chemical Substances Transcription Factors
    Language English
    Publishing date 2023-06-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3287-1_5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Non-noble metal-catalyzed cross-dehydrogenation coupling (CDC) involving ether α-C(sp

    Yu, Hui / Xu, Feng

    Beilstein journal of organic chemistry

    2023  Volume 19, Page(s) 1259–1288

    Abstract: Ether derivatives are widespread as essential building blocks in various drugs, natural products, agrochemicals, and materials. Modern economy requires developing green strategies with improved efficiency and reduction of waste. Due to its atom and step- ... ...

    Abstract Ether derivatives are widespread as essential building blocks in various drugs, natural products, agrochemicals, and materials. Modern economy requires developing green strategies with improved efficiency and reduction of waste. Due to its atom and step-economy, the cross-dehydrogenative coupling (CDC) reaction has become a major strategy for ether functionalization. This review covers C-H/C-H cross-coupling reactions of ether derivatives with various C-H bond substrates via non-noble metal catalysts (Fe, Cu, Co, Mn, Ni, Zn, Y, Sc, In, Ag). We discuss advances achieved in these CDC reactions and hope to attract interest in developing novel methodologies in this field of organic chemistry.
    Language English
    Publishing date 2023-09-06
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2192461-2
    ISSN 1860-5397
    ISSN 1860-5397
    DOI 10.3762/bjoc.19.94
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Advances in the synthesis of nitrogen-containing heterocyclic compounds by

    Yu, Hui / Xu, Feng

    RSC advances

    2023  Volume 13, Issue 12, Page(s) 8238–8253

    Abstract: Nitrogen-containing heterocyclic compounds are prevalent in various natural products, medicines, agrochemicals, and organic functional materials. Among strategies to prepare nitrogen-containing heterocyclic compounds, pathways involving benzyne ... ...

    Abstract Nitrogen-containing heterocyclic compounds are prevalent in various natural products, medicines, agrochemicals, and organic functional materials. Among strategies to prepare nitrogen-containing heterocyclic compounds, pathways involving benzyne intermediates are attractive given that they can readily assemble highly diverse heterocyclic compounds in a step-economical manner under transition-metal-free conditions. The synthesis of nitrogen-containing heterocyclic compounds from benzyne intermediates offers an alternative strategy to the conventional metal-catalyzed activation approaches. In the past years, chemists have witnessed the revival of benzyne chemistry, mainly attributed to the wide application of various novel benzyne precursors. The cycloaddition of benzynes is a powerful tool for the synthesis of nitrogen-containing heterocyclic compounds, which can be constructed by [
    Language English
    Publishing date 2023-03-13
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra00400g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Epstein-Barr Virus History and Pathogenesis.

    Yu, Hui / Robertson, Erle S

    Viruses

    2023  Volume 15, Issue 3

    Abstract: Epstein-Barr virus (EBV) is the first identified human oncogenic virus that can establish asymptomatic life-long persistence. It is associated with a large spectrum of diseases, including benign diseases, a number of lymphoid malignancies, and epithelial ...

    Abstract Epstein-Barr virus (EBV) is the first identified human oncogenic virus that can establish asymptomatic life-long persistence. It is associated with a large spectrum of diseases, including benign diseases, a number of lymphoid malignancies, and epithelial cancers. EBV can also transform quiescent B lymphocytes into lymphoblastoid cell lines (LCLs) in vitro. Although EBV molecular biology and EBV-related diseases have been continuously investigated for nearly 60 years, the mechanism of viral-mediated transformation, as well as the precise role of EBV in promoting these diseases, remain a major challenge yet to be completely explored. This review will highlight the history of EBV and current advances in EBV-associated diseases, focusing on how this virus provides a paradigm for exploiting the many insights identified through interplay between EBV and its host during oncogenesis, and other related non-malignant disorders.
    MeSH term(s) Humans ; Herpesvirus 4, Human/metabolism ; Epstein-Barr Virus Infections ; B-Lymphocytes ; Cell Line ; Carcinogenesis
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15030714
    Database MEDical Literature Analysis and Retrieval System OnLINE

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