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  1. Article ; Online: Normothermic machine perfusion for liver transplantation: current state and future directions.

    Lindemann, Jessica / Yu, Jennifer / Doyle, Mb Majella

    Current opinion in organ transplantation

    2024  Volume 29, Issue 3, Page(s) 186–194

    Abstract: Purpose of review: The number of patients on the liver transplant waitlist continues to grow and far exceeds the number of livers available for transplantation. Normothermic machine perfusion (NMP) allows for ex-vivo perfusion under physiologic ... ...

    Abstract Purpose of review: The number of patients on the liver transplant waitlist continues to grow and far exceeds the number of livers available for transplantation. Normothermic machine perfusion (NMP) allows for ex-vivo perfusion under physiologic conditions with the potential to significantly increase organ yield and expand the donor pool.
    Recent findings: Several studies have found increased utilization of donation after cardiac death and extended criteria brain-dead donor livers with implementation of NMP, largely due to the ability to perform viability testing during machine perfusion. Recently, proposed viability criteria include lactate clearance, maintenance of perfusate pH more than 7.2, ALT less than 6000 u/l, evidence of glucose metabolism and bile production. Optimization of liver grafts during NMP is an active area of research and includes interventions for defatting steatotic livers, preventing ischemic cholangiopathy and rejection, and minimizing ischemia reperfusion injury.
    Summary: NMP has resulted in increased organ utilization from marginal donors with acceptable outcomes. The added flexibility of prolonged organ storage times has the potential to improve time constraints and transplant logistics. Further research to determine ideal viability criteria and investigate ways to optimize marginal and otherwise nontransplantable liver grafts during NMP is warranted.
    MeSH term(s) Liver Transplantation/adverse effects ; Liver Transplantation/methods ; Liver Transplantation/trends ; Humans ; Perfusion/methods ; Perfusion/adverse effects ; Perfusion/trends ; Perfusion/instrumentation ; Organ Preservation/methods ; Organ Preservation/adverse effects ; Organ Preservation/trends ; Tissue Donors/supply & distribution ; Graft Survival ; Treatment Outcome ; Donor Selection ; Temperature ; Reperfusion Injury/prevention & control ; Reperfusion Injury/etiology ; Tissue Survival ; Animals
    Language English
    Publishing date 2024-03-14
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1390429-2
    ISSN 1531-7013 ; 1087-2418
    ISSN (online) 1531-7013
    ISSN 1087-2418
    DOI 10.1097/MOT.0000000000001141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5609: Show issues Location:
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  2. Book ; Online: The Mental Health Association of San Francisco Partner Organizations Meet Their Goals in Stigma Reduction Efforts

    Cerully, Jennifer L / Collins, Rebecca L / Wong, Eunice C / Yu, Jennifer

    Results of a Qualitative Evaluation of the Technical Assistance Process

    2015  

    Keywords History of the Americas ; Psychology ; Social research & statistics ; History ; Sociology
    Language English
    Size 1 Online-Ressource
    Publisher RAND Corporation
    Document type Book ; Online
    Note English
    HBZ-ID HT030612928
    ISBN 9780833093752 ; 0833093754
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: CalMHSA Stigma and Discrimination Reduction Online Resources

    Cerully, Jennifer L / Kase, Courtney Ann / Collins, Rebecca L / Wong, Eunice C / Yu, Jennifer

    Highlights from an Evaluation of Web Analytic Data

    2015  

    Keywords History of the Americas ; Psychology ; History
    Language English
    Size 1 Online-Ressource
    Publisher RAND Corporation
    Document type Book ; Online
    Note English
    HBZ-ID HT030609892
    ISBN 9780833093714 ; 0833093711
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Evaluating the California Mental Health Services Authority's Stigma and Discrimination Reduction Initiative

    Collins, Rebecca L / Cerully, Jennifer L / Wong, Eunice C / Golan, Shari / Yu, Jennifer

    Year 1 Findings

    2014  

    Keywords History of the Americas ; Psychology ; Social discrimination & inequality ; Sociology ; History
    Language English
    Size 1 Online-Ressource
    Publisher RAND Corporation
    Document type Book ; Online
    Note English
    HBZ-ID HT030609614
    ISBN 9780833085269 ; 0833085263
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article: Primary Non-Function of Hepatic Allograft With Preexisting Microvesicular Steatosis/Foamy Degeneration and Mild Large-Droplet Macrovesicular Steatosis.

    Limia, Melissa E / Liu, Xiu Li / Yu, Jennifer / Byrnes, Kathleen

    Gastroenterology research

    2024  Volume 17, Issue 1, Page(s) 37–40

    Abstract: It has been established that more than mild large-droplet macrovesicular steatosis (LD-MAS) is associated with increased risk of graft non-function. In contrast, even severe small-droplet macrovesicular steatosis (SD-MAS) has been found to be less ... ...

    Abstract It has been established that more than mild large-droplet macrovesicular steatosis (LD-MAS) is associated with increased risk of graft non-function. In contrast, even severe small-droplet macrovesicular steatosis (SD-MAS) has been found to be less prognostically significant. It remains unclear if a donor liver with diffuse microvesicular steatosis is associated with an increased risk of graft dysfunction. A 56-year-old male with alcoholic cirrhosis was transplanted with a liver from a 42-year-old overweight male donor after brain death. The frozen section of the donor liver biopsy taken at harvest showed diffusely enlarged clear/foamy hepatocytes and mild LD-MAS (about 5-10% of total tissue). The reperfusion liver biopsy taken at time 0 of transplantation showed hemorrhage, pale and enlarged hepatocytes, and mild LD-MAS (about 10% of total tissue) with lipopeliosis. The graft became non-functional, and the patient was re-transplanted 24 h after the initial transplantation. Histologic examination of the failed liver allograft showed extensive hemorrhagic necrosis, neutrophilic inflammation, diffuse microvesicular steatosis, and large extracellular fat droplets (about 20% of total tissue). This case demonstrates that precautions are needed to avoid using livers with diffuse and severe microvesicular steatosis.
    Language English
    Publishing date 2024-02-28
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 2475913-2
    ISSN 1918-2813 ; 1918-2805
    ISSN (online) 1918-2813
    ISSN 1918-2805
    DOI 10.14740/gr1687
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Downstaging Hepatocellular Carcinoma before Transplantation: Role of Immunotherapy Versus Locoregional Approaches.

    Lindemann, Jessica / Yu, Jennifer / Doyle, Maria Bernadette Majella

    Surgical oncology clinics of North America

    2023  Volume 33, Issue 1, Page(s) 143–158

    Abstract: Hepatocellular carcinoma (HCC) continues to be a leading cause of cancer-related death in the United States. With advances in locoregional therapy for unresectable HCC during the last 2 decades and the recent expansion of transplant criteria for HCC, as ... ...

    Abstract Hepatocellular carcinoma (HCC) continues to be a leading cause of cancer-related death in the United States. With advances in locoregional therapy for unresectable HCC during the last 2 decades and the recent expansion of transplant criteria for HCC, as well as ongoing organ shortages, patients are spending more time on the waitlist, which has resulted in an increased usage of locoregional therapies. The plethora of molecularly targeted therapies and immune checkpoint inhibitors under investigation represent the new horizon of treatment of HCC not only in advanced stages but also potentially at every stage of diagnosis and management.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/therapy ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/therapy ; Liver Neoplasms/pathology ; Liver Transplantation ; Neoplasm Staging ; Immunotherapy/methods
    Language English
    Publishing date 2023-09-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1196919-2
    ISSN 1558-5042 ; 1055-3207
    ISSN (online) 1558-5042
    ISSN 1055-3207
    DOI 10.1016/j.soc.2023.07.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Se 1339: Show issues Location:
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  7. Article ; Online: Mathematics performance, response time, and enjoyment of eighth-grade autistic students and their general education peers.

    Wei, Xin / Zhang, Susu / Zhang, Jihong / Yu, Jennifer

    Autism : the international journal of research and practice

    2023  Volume 27, Issue 8, Page(s) 2518–2529

    Abstract: For autistic students receiving special education services, little is known about their relative strengths, weaknesses, and enjoyment across different math content areas; their overall math interest and persistence are also not well-studied. Using the ... ...

    Abstract For autistic students receiving special education services, little is known about their relative strengths, weaknesses, and enjoyment across different math content areas; their overall math interest and persistence are also not well-studied. Using the 2017 eighth-grade National Assessment of Education Progress data, this study finds, relative to general education peers with the same math proficiency level, autistic students scored higher and exhibited faster speed in solving visuospatial problems (e.g. identifying figures), but scored lower on math word problems with complex language or social context. Autistic students reported a higher level of enjoyment in solving math problems related to finding areas of shapes or figures but a lower level of persistence than their non-autistic, general education peers. Our work points out the need to help autistic students overcome their weaknesses in word problems and develop their mathematical persistence.
    Language English
    Publishing date 2023-05-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1338513-6
    ISSN 1461-7005 ; 1362-3613
    ISSN (online) 1461-7005
    ISSN 1362-3613
    DOI 10.1177/13623613231168241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5838: Show issues Location:
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  8. Article ; Online: Triage to electrocardiogram sign-off time in patients with acute coronary syndrome at a metropolitan Sydney hospital.

    Turner, Dane / Yu, Jennifer / Murphy, David / Chiew, Angela

    Emergency medicine Australasia : EMA

    2023  Volume 35, Issue 4, Page(s) 624–629

    Abstract: Objective: To compare the time from triage to ECG sign-off in patients with acute coronary syndrome, before and after the introduction of an electronic medical record-integrated ECG workflow system (Epiphany). Additionally, to assess for any correlation ...

    Abstract Objective: To compare the time from triage to ECG sign-off in patients with acute coronary syndrome, before and after the introduction of an electronic medical record-integrated ECG workflow system (Epiphany). Additionally, to assess for any correlation between patient characteristics and ECG sign-off times.
    Methods: A retrospective, single-centre cohort study was performed at Prince of Wales Hospital, Sydney. Patients were included if they were over 18 years, presented to Prince of Wales Hospital ED during 2021, had an ED diagnosis code of 'ACS', 'UA', 'NSTEMI' or 'STEMI' and were subsequently admitted under the cardiology team. ECG sign-off times and demographic data were compared between patients presenting prior to 29 June (pre-Epiphany group) and those presenting after (post-Epiphany group). Those without ECGs signed-off were excluded.
    Results: There were 200 patients (100 each group) included in the statistical analysis. There was a significant decrease in the median triage to ECG sign-off time, from 35 min (IQR 18-69) pre-Epiphany, to 21 min (IQR 13-37) post-Epiphany. There were only 10 (5%) patients in the pre-Epiphany group and 16 (8%) in the post-Epiphany group, who had ECG sign-off times less than the 10-min. There was no correlation between gender, triage category, age or time of shift with triage to ECG sign-off time.
    Conclusions: The introduction of the Epiphany system has significantly reduced the triage to ECG sign-off time in the ED. Despite this, there remains a large proportion of patients with acute coronary syndrome who do not have an ECG signed-off within the guideline-recommended 10 min.
    MeSH term(s) Humans ; Triage ; Acute Coronary Syndrome/diagnosis ; Retrospective Studies ; Cohort Studies ; Emergency Service, Hospital ; Electrocardiography ; Hospitals, Urban
    Language English
    Publishing date 2023-02-16
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2161824-0
    ISSN 1742-6723 ; 1742-6731 ; 1035-6851
    ISSN (online) 1742-6723
    ISSN 1742-6731 ; 1035-6851
    DOI 10.1111/1742-6723.14181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5940: Show issues Location:
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  9. Article ; Online: Improving Pediatric Fellows' Feedback Skills and Confidence Through Objective Structured Examinations.

    Yu, Jennifer C / Rhee, Kyung E / Dworsky, Zephyr D / Larrow, Annie / Passarelli, Patrick / Patel, Aarti

    Journal of graduate medical education

    2024  Volume 16, Issue 1, Page(s) 64–69

    Abstract: ... ...

    Abstract Background
    MeSH term(s) Humans ; Child ; Feedback ; Internship and Residency ; Curriculum ; Clinical Competence ; Education, Medical, Graduate/methods ; Fellowships and Scholarships
    Language English
    Publishing date 2024-02-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2578612-X
    ISSN 1949-8357 ; 1949-8357
    ISSN (online) 1949-8357
    ISSN 1949-8357
    DOI 10.4300/JGME-D-23-00332.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Data Resource Profile: The Cardiac Analytics and Innovation (CardiacAI) Data Repository.

    Blake, Victoria / Jorm, Louisa / Yu, Jennifer / Lee, Astin / Gallego, Blanca / Ooi, Sze-Yuan

    International journal of epidemiology

    2024  Volume 53, Issue 2

    MeSH term(s) Humans ; Electronic Health Records ; Databases, Factual
    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 187909-1
    ISSN 1464-3685 ; 0300-5771
    ISSN (online) 1464-3685
    ISSN 0300-5771
    DOI 10.1093/ije/dyae040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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