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Article:

Wu, Tian-Rou / Xu, Jian / An, Ming-Tai / Yu, Jiang-Hong / Liu, Feng / Chen, Zheng-Ren

2024 Volume 237, Page(s) 37–49

Abstract: ... ...

Abstract	Hypericumliboense
Language	English
Publishing date	2024-01-12
Publishing country	Bulgaria
Document type	Journal Article
ZDB-ID	2579891-1
ISSN	1314-2003 ; 1314-2011
ISSN (online)	1314-2003
ISSN	1314-2011
DOI	10.3897/phytokeys.237.110482
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: New meroterpenoids and C-methylated flavonoid isolated from Baeckea frutescens

HOU, Ji-Qin / ZHAO, Heng / YU, Jiang-Hong / CHEN, Ling-Jun / WANG, Hao

Chinese journal of natural medicines. 2020 May, v. 18, no. 5

2020

Abstract: Phytochemical investigation of the aerial parts of Baeckea frutescens resulted in the isolation of three new mono- or sesquiterpene-based meroterpenoids, frutescones S-U (1-3), and one pair of new (±)-5,7-dihydroxy-8-isobutyryl-6-methyldihydroflavonol (4) ...

Abstract	Phytochemical investigation of the aerial parts of Baeckea frutescens resulted in the isolation of three new mono- or sesquiterpene-based meroterpenoids, frutescones S-U (1-3), and one pair of new (±)-5,7-dihydroxy-8-isobutyryl-6-methyldihydroflavonol (4). Their structures and absolute configurations were established by HR-ESI-MS, 1D and 2D NMR, and quantum chemical ECD calculation. Compound 1 exhibited inhibitory effect on NO production in LPS-activated RAW 264.7 macrophages with an IC₅₀ value being 0.81 μmol·L⁻¹.
Keywords	aerial parts ; flavonoids ; macrophages ; meroterpenoids ; quantum mechanics
Language	English
Dates of publication	2020-05
Size	p. 379-384.
Publishing place	Elsevier B.V.
Document type	Article
Note	NAL-light
ZDB-ID	2192577-X
ISSN	1875-5364 ; 2095-6975 ; 1672-3651
ISSN (online)	1875-5364
ISSN	2095-6975 ; 1672-3651
DOI	10.1016/S1875-5364(20)30044-3
Database	NAL-Catalogue (AGRICOLA)

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Article:

Yu, Jiang-Hong / Zhang, Wen-Di / Qin, Fei / Xia, Chang-Ying / Qin, Ying / An, Ming-Tai / Gadagkar, Sudhindra R / Yu, Sheng-Xiang

PhytoKeys

2022 Volume 212, Page(s) 13–27

Abstract: ... ...

Abstract	Impatiensyunlingensis
Language	English
Publishing date	2022-10-27
Publishing country	Bulgaria
Document type	Journal Article
ZDB-ID	2579891-1
ISSN	1314-2003 ; 1314-2011
ISSN (online)	1314-2003
ISSN	1314-2011
DOI	10.3897/phytokeys.212.89347
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Article ; Online: Impatiens yunlingensis (Balsaminaceae), a new species from Yunnan, China

Yu, Jiang-Hong / Zhang, Wen-Di / Qin, Fei / Xia, Chang-Ying / Qin, Ying / An, Ming-Tai / Gadagkar, Sudhindra R. / Yu, Sheng-Xiang

PhytoKeys. 2022 Oct. 27, v. 212 p.13-27

2022

Abstract: AbstractImpatiens yunlingensis S.X. Yu, Chang Y. Xia & J.H. Yu (Balsaminaceae), a species new to science discovered in Yunnan, China, is described and illustrated here, along with its phylogenetic position among other Impatiens species. Morphological, ... ...

Abstract	AbstractImpatiens yunlingensis S.X. Yu, Chang Y. Xia & J.H. Yu (Balsaminaceae), a species new to science discovered in Yunnan, China, is described and illustrated here, along with its phylogenetic position among other Impatiens species. Morphological, micro-morphological and molecular evidence is presented as an attestation of its novelty. Impatiens yunlingensis is similar to I. delavayi in having coarsely crenate leave margins, bracts in the upper part, ca. ⁴/₅ length of the pedicels, saccate lower sepal with shallowly bifid spur, linear capsules, and elliptic-oblong, tuberculate seeds, but differs from I. delavayi with lateral sepals 4 (vs. 2), lateral united petal basal lobes subtriangular (vs. dolabriform), and seeds’ surface equipped with tubercular ornamentation mostly covered with grain shaped appendages (vs. glabrous and without grain shaped appendages on the top).
Keywords	Impatiens ; new species ; phylogeny ; China ; Morphology ; pollen grains ; seed micromorphology ; taxonomy
Language	English
Dates of publication	2022-1027
Size	p. 13-27.
Publishing place	Pensoft Publishers
Document type	Article ; Online
ZDB-ID	2579891-1
ISSN	1314-2003 ; 1314-2011
ISSN (online)	1314-2003
ISSN	1314-2011
DOI	10.3897/phytokeys.212.89347
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: New meroterpenoids and C-methylated flavonoid isolated from Baeckea frutescens.

Hou, Ji-Qin / Zhao, Heng / Yu, Jiang-Hong / Chen, Ling-Jun / Wang, Hao

Chinese journal of natural medicines

2020 Volume 18, Issue 5, Page(s) 379–384

Abstract	Phytochemical investigation of the aerial parts of Baeckea frutescens resulted in the isolation of three new mono- or sesquiterpene-based meroterpenoids, frutescones S-U (1-3), and one pair of new (±)-5,7-dihydroxy-8-isobutyryl-6-methyldihydroflavonol (4). Their structures and absolute configurations were established by HR-ESI-MS, 1D and 2D NMR, and quantum chemical ECD calculation. Compound 1 exhibited inhibitory effect on NO production in LPS-activated RAW 264.7 macrophages with an IC
MeSH term(s)	Animals ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/isolation & purification ; Drugs, Chinese Herbal/pharmacology ; Flavonoids/chemistry ; Flavonoids/isolation & purification ; Flavonoids/pharmacology ; Mass Spectrometry ; Mice ; Molecular Structure ; Myrtaceae/chemistry ; Plant Components, Aerial/chemistry ; RAW 264.7 Cells ; Terpenes/chemistry ; Terpenes/isolation & purification ; Terpenes/pharmacology
Chemical Substances	Drugs, Chinese Herbal ; Flavonoids ; Terpenes
Language	English
Publishing date	2020-05-23
Publishing country	China
Document type	Journal Article
ZDB-ID	2192577-X
ISSN	1875-5364 ; 2095-6975 ; 1672-3651
ISSN (online)	1875-5364
ISSN	2095-6975 ; 1672-3651
DOI	10.1016/S1875-5364(20)30044-3
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Article ; Online: Biomimetic total syntheses of baefrutones A-D, baeckenon B, and frutescones A, D-F.

Hou, Ji-Qin / Yu, Jiang-Hong / Zhao, Heng / Dong, Ying-Ying / Peng, Qiu-Shi / Zhang, Bao-Bao / Wang, Hao

Organic & biomolecular chemistry

2020 Volume 18, Issue 6, Page(s) 1135–1139

Abstract: Biomimetic total syntheses of baefrutones A-D (1-4), baeckenon B (5), and frutescones A, D-F (6-9), isolated from the leaves of Baeckea frutescens, were achieved in 9, 8, and 5 steps, respectively, in moderate to good yields (72-83%). The synthetic ... ...

Abstract	Biomimetic total syntheses of baefrutones A-D (1-4), baeckenon B (5), and frutescones A, D-F (6-9), isolated from the leaves of Baeckea frutescens, were achieved in 9, 8, and 5 steps, respectively, in moderate to good yields (72-83%). The synthetic routes feature the Michael addition, oxidative [4 + 2] cycloaddition, and water-promoted Diels-Alder click reactions as the key steps. This study helped gain thorough mechanistic insights into the biosynthetic origins and provided a facile approach for the construction of a library of natural tasmanone-based meroterpenoid analogues. Moreover, compounds 1-9 show potent inhibitory effects against S. paratyphi and/or C. albicans with MIC values of 3.125-25 μg mL
MeSH term(s)	Biomimetic Materials/chemical synthesis ; Biomimetic Materials/chemistry ; Biomimetic Materials/pharmacology ; Candida albicans/drug effects ; Cycloaddition Reaction ; Density Functional Theory ; Dose-Response Relationship, Drug ; Microbial Sensitivity Tests ; Molecular Structure ; Monoterpenes/chemical synthesis ; Monoterpenes/chemistry ; Monoterpenes/pharmacology ; Oxidation-Reduction ; Pseudomonas aeruginosa/drug effects ; Salmonella/drug effects ; Staphylococcus aureus/drug effects ; Stereoisomerism ; Structure-Activity Relationship ; Terpenes/chemical synthesis ; Terpenes/chemistry ; Terpenes/pharmacology
Chemical Substances	Monoterpenes ; Terpenes ; frutescone
Language	English
Publishing date	2020-01-22
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2097583-1
ISSN	1477-0539 ; 1477-0520
ISSN (online)	1477-0539
ISSN	1477-0520
DOI	10.1039/c9ob02490e
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Gasless laparoscopic surgery plus abdominal wall lifting for giant hiatal hernia-our single-center experience.

Yu, Jiang-Hong / Wu, Ji-Xiang / Yu, Lei / Li, Jian-Ye

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban

2016 Volume 36, Issue 6, Page(s) 923–926

Abstract: Giant hiatal hernia (GHH) comprises 5% of hiatal hernia and is associated with significant complications. The traditional operative procedure, no matter transthoracic or transabdomen repair of giant hiatal hernia, is characteristic of more invasion and ... ...

Abstract	Giant hiatal hernia (GHH) comprises 5% of hiatal hernia and is associated with significant complications. The traditional operative procedure, no matter transthoracic or transabdomen repair of giant hiatal hernia, is characteristic of more invasion and more complications. Although laparoscopic repair as a minimally invasive surgery is accepted, a part of patients can not tolerate pneumoperitoneum because of combination with cardiopulmonary diseases or severe posterior mediastinal and neck emphesema during operation. The aim of this article was to analyze our experience in gasless laparoscopic repair with abdominal wall lifting to treat the giant hiatal hernia. We performed a retrospective review of patients undergoing gasless laparoscopic repair of GHH with abdominal wall lifting from 2012 to 2015 at our institution. The GHH was defined as greater than one-third of the stomach in the chest. Gasless laparoscopic repair of GHH with abdominal wall lifting was attempted in 27 patients. Mean age was 67 years. The results showed that there were no conversions to open surgery and no intraoperative deaths. The mean duration of operation was 100 min (range: 90-130 min). One-side pleura was injured in 4 cases (14.8%). The mean postoperative length of stay was 4 days (range: 3-7 days). Median follow- up was 26 months (range: 6-38 months). Transient dysphagia for solid food occurred in three patients (11.1%), and this symptom disappeared within three months. There was one patient with recurrent hiatal hernia who was reoperated on. Two patients still complained of heartburn three months after surgery. Neither reoperation nor endoscopic treatment due to signs of postoperative esophageal stenosis was required in any patient. Totally, satisfactory outcome was reported in 88.9% patients. It was concluded that the gasless laparoscopic approach with abdominal wall lifting to the repair of GHH is feasible, safe, and effective for the patients who cannot tolerate the pneumoperitoneum.
MeSH term(s)	Abdominal Wall/surgery ; Aged ; Esophageal Stenosis/etiology ; Female ; Fundoplication/adverse effects ; Fundoplication/methods ; Heartburn/etiology ; Hernia, Hiatal/diagnosis ; Hernia, Hiatal/surgery ; Humans ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Male ; Middle Aged ; Pneumoperitoneum, Artificial/adverse effects ; Postoperative Complications
Language	English
Publishing date	2016-12
Publishing country	China
Document type	Evaluation Studies ; Journal Article
ZDB-ID	2090603-1
ISSN	1993-1352 ; 1672-0733 ; 0257-716X
ISSN (online)	1993-1352
ISSN	1672-0733 ; 0257-716X
DOI	10.1007/s11596-016-1685-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Targeting mTORC2/HDAC3 Inhibits Stemness of Liver Cancer Cells Against Glutamine Starvation.

Zhang, Hui-Lu / Chen, Ping / Yan, He-Xin / Fu, Gong-Bo / Luo, Fei-Fei / Zhang, Jun / Zhao, Shi-Min / Zhai, Bo / Yu, Jiang-Hong / Chen, Lin / Cui, Hao-Shu / Chen, Jian / Huang, Shuai / Zeng, Jun / Xu, Wei / Wang, Hong-Yang / Liu, Jie

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

2022 Volume 9, Issue 20, Page(s) e2103887

Abstract: Cancer cells are addicted to glutamine. However, cancer cells often suffer from glutamine starvation, which largely results from the fast growth of cancer cells and the insufficient vascularization in the interior of cancer tissues. Herein, based on ... ...

Abstract	Cancer cells are addicted to glutamine. However, cancer cells often suffer from glutamine starvation, which largely results from the fast growth of cancer cells and the insufficient vascularization in the interior of cancer tissues. Herein, based on clinical samples, patient-derived cells (PDCs), and cell lines, it is found that liver cancer cells display stem-like characteristics upon glutamine shortage due to maintaining the stemness of tumor initiating cells (TICs) and even promoting transformation of non-TICs into stem-like cells by glutamine starvation. Increased expression of glutamine synthetase (GS) is essential for maintaining and promoting stem-like characteristics of liver cancer cells during glutamine starvation. Mechanistically, glutamine starvation activates Rictor/mTORC2 to induce HDAC3-mediated deacetylation and stabilization of GS. Rictor is significantly correlated with the expression of GS and stem marker OCT4 at tumor site, and closely correlates with poor prognosis of hepatocellular carcinomas. Inhibiting components of mTORC2-HDAC3-GS axis decrease TICs and promote xenografts regression upon glutamine-starvation therapy. Collectively, the data provides novel insights into the role of Rictor/mTORC2-HDAC3 in reprogramming glutamine metabolism to sustain stemness of cancer cells. Targeting Rictor/HDAC3 may enhance the efficacy of glutamine-starvation therapy and limit the rapid growth and malignant progression of tumors.
MeSH term(s)	Cell Line ; Glutamate-Ammonia Ligase ; Glutamine/deficiency ; Glutamine/metabolism ; Histone Deacetylases ; Humans ; Liver Neoplasms ; Mechanistic Target of Rapamycin Complex 2/metabolism ; Transcription Factors
Chemical Substances	Transcription Factors ; Glutamine (0RH81L854J) ; Mechanistic Target of Rapamycin Complex 2 (EC 2.7.11.1) ; Histone Deacetylases (EC 3.5.1.98) ; histone deacetylase 3 (EC 3.5.1.98) ; Glutamate-Ammonia Ligase (EC 6.3.1.2)
Language	English
Publishing date	2022-02-20
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2808093-2
ISSN	2198-3844 ; 2198-3844
ISSN (online)	2198-3844
ISSN	2198-3844
DOI	10.1002/advs.202103887
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Article: Gene analysis of two cases with CisAB/B blood subgroup.

Jiao, Li-Xin / Yu, Jiang-Hong / Yu, Xiao-Li / Chen, Lin / Han, Yu / Yang, Fan

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis

2017 Volume 56, Issue 2, Page(s) 223–225

Abstract: Objective: To identify the precise ABO blood type subgroups with genotyping.: Method: We screened ABO blood type from voluntary blood donors in our blood collection center. Samples were first examined with a routine serological method. Samples with ... ...

Abstract	Objective: To identify the precise ABO blood type subgroups with genotyping. Method: We screened ABO blood type from voluntary blood donors in our blood collection center. Samples were first examined with a routine serological method. Samples with ambiguous results were further examined with genotyping to identify ABO subgroups. Results: Two samples identified as A Conclusion: It may be difficult to identify non-typical AB patients with a routine serological method. Genotyping is a more precise method to identify blood subgroups.
Language	English
Publishing date	2017-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2046795-3
ISSN	1878-1683 ; 1473-0502
ISSN (online)	1878-1683
ISSN	1473-0502
DOI	10.1016/j.transci.2016.12.002
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Article: Gene identification of rare B(A) blood group.

Jiao, Li-Xin / Zhang, Jing-Ying / Chen, Lin / Yu, Xiao-Li / Han, Yu / Yang, Fan / Yu, Jiang-Hong / Liu, Ling-Ling / Lang, Yue

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis

2017 Volume 56, Issue 6, Page(s) 855–857

Abstract: Objective: To study serologic and gene characteristics of the B(A) blood group of blood donation volunteers in Jilin Province, China.: Methods: ABO subgroups were identified by standard serologic techniques in ABO typing discrepancy samples from all ... ...

Abstract	Objective: To study serologic and gene characteristics of the B(A) blood group of blood donation volunteers in Jilin Province, China. Methods: ABO subgroups were identified by standard serologic techniques in ABO typing discrepancy samples from all donors at the Jilin Blood Center (410,354 non-repeat donors). DNA (deoxyribonucleic acid) was collected from each sample and PCR (polymerase chain reaction) was used to sequence exons 6 and 7 and intron 6, part 5 from the ABO subgroup samples. PCR products were sequenced to identify ABO subgroups and the B(A) allele. Results: Four cases of B(A) blood type were found after sequencing, including two different alleles: B(A)02 and B(A)04. Three of the four alleles were B(A)04. Conclusion: Among blood donation volunteers in Jilin Province, China, B(A)04 is the most common B(A) blood group allele, followed by B(A)02. The B(A) blood group is associated with a complicated serologic phenotype and DNA detection is necessary for this atypical phenotype sample.
MeSH term(s)	ABO Blood-Group System/genetics ; Adult ; Alleles ; Female ; Genotype ; Humans ; Male ; Middle Aged ; Young Adult
Chemical Substances	ABO Blood-Group System
Language	English
Publishing date	2017-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2046795-3
ISSN	1878-1683 ; 1473-0502
ISSN (online)	1878-1683
ISSN	1473-0502
DOI	10.1016/j.transci.2017.09.001
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