LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 7487

Search options

  1. Article ; Online: Extending Quality Function Deployment and Analytic Hierarchy Process under Interval-Valued Fuzzy Environment for Evaluating Port Sustainability

    Yu-Jie Wang

    Sustainability, Vol 15, Iss 5730, p

    2023  Volume 5730

    Abstract: To confront the related problems of environmental protection, energy saving, and carbon reduction, sustainability has been a prominent issue for enterprises seeking to meet the requirements of the Earth Summit’ sustainable development goals (SDGs). ... ...

    Abstract To confront the related problems of environmental protection, energy saving, and carbon reduction, sustainability has been a prominent issue for enterprises seeking to meet the requirements of the Earth Summit’ sustainable development goals (SDGs). Basically, sustainability evaluation of enterprises must be considered from environmental, social, and economic perspectives, recognized as quality requirements. Numerous enterprises, especially for international ports, must pay attention to these requirements in expressing their corporate social responsibility (CSR) for decreasing marine pollution. Practically, the three requirements may be dependent under uncertain environments, and rationally evaluated by fuzzy multi-criteria decision-making (FMCDM) with dependent evaluation criteria (DEC). In other words, evaluating port sustainability, containing location expanding, should belong to FMCDM with DEC. For DEC under uncertain environments, fuzzy extension of the analytic network process (ANP) is a feasible solution to solve the above problems. However, fuzzy computations of ANP are heavily complicated; thus, we desire to combine quality function deployment (QFD) with the analytic hierarchy process (AHP) under the interval-valued fuzzy environment (IVFE) into a hybrid method for evaluating port sustainability. In numerous multi-criteria decision-making (MCDM) efforts, AHP was often extended into FMCDM to encompass the imprecision and vagueness of data, but the extension was properly used for FMCDM with independent evaluation criteria (IDEC). Herein, QFD is utilized to express the dependent relationships between criteria, and thus transforms IDEC into DEC for the evaluation of port sustainability. Through the hybrid method, QFD is combined with AHP to replace ANP under IVFE, the complicated ties of ANP-corresponding interval-valued fuzzy numbers (IVFNs) are overcome, and the problem of evaluating port sustainability is rationally solved.
    Keywords analytic hierarchy process (AHP) ; dependent evaluation criteria (DEC) ; interval-valued fuzzy environment (IVFE) ; quality function deployment (QFD) ; sustainability ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 690
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  2. Book ; Online ; E-Book: Advanced Application of Arthroscopy

    Liu, Yu-jie / Xue, Jing / Huang, Chang-ming / Li, Chun-bao

    A Practical Guide with Illustrative Cases

    2020  

    Abstract: This book provides novel arthroscopy techniques and applications to clinical practitioners, including sports medicine therapeutics, orthopaedic surgeons, specialist training candidates, rehabilitation clinicians. Small incisions per minimally invasive ... ...

    Author's details edited by Yu-jie Liu, Jing Xue, Chang-ming Huang, Chun-bao Li
    Abstract This book provides novel arthroscopy techniques and applications to clinical practitioners, including sports medicine therapeutics, orthopaedic surgeons, specialist training candidates, rehabilitation clinicians. Small incisions per minimally invasive surgery using a camera mounted on a thin tube to visualize, repair and reconstruct joint-associated structures are accepted and welcomed by the sports medicine field. Arthroscopy technique as a minimally invasive surgical method, in Orthopeadics is not only for the treatment of intra-articular diseases but also an advanced conception for treatment of extra-articular diseases and peri-articular fractures. After performing years of arthroscopy, authors intend to provide an elite technique demonstration of each procedure, including indications, technique, complications, and results. There are three main parts of the book, including the extra-articular application of arthroscopy techniques, arthroscopic minimally invasive techniques for the treatment of intra-articular fractures, and Innovative technology for repair and reconstruction of bone and joint injuries. Key technical points and experience of arthroscopic repair of joint injuries, dislocation of joints, fixation of the intra-articular fractures, ligament release for limbs are illustrated. Special situations such as congenital torticollis, deltoid contracture, gluteal muscle contracture, bone grafting, removal of locking plate and screw and benign tumors treatment are also included.
    Keywords Orthopedics ; Sports medicine ; Sports Medicine ; Artroscòpia ; Cirurgia ortopèdica ; Medicina esportiva
    Subject code 617.4720597
    Language English
    Size 1 online resource (xxi, 223 pages) :, illustrations
    Edition 1st ed. 2020.
    Publisher Springer Singapore ; Imprint: Springer
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-15-4684-3 ; 981-15-4683-5 ; 978-981-15-4684-6 ; 978-981-15-4683-9
    DOI 10.1007/978-981-15-4684-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Kategorien

  3. Book: Microwave ablation treatment of solid tumors

    Liang, Ping / Yu, Xiao-ling / Yu, Jie

    2015  

    Author's details Ping Liang ; Xiao-ling Yu ; Jie Yu ed
    Language English
    Size IX, 344 S. : zahlr. Ill., graph. Darst.
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT018489826
    ISBN 978-94-017-9314-8 ; 94-017-9314-X ; 9789401793155 ; 9401793158
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

  4. Article ; Online: What is the Potential Cause for the Predominance of GII.2[P16] Norovirus in Acute Gastroenteritis Outbreaks in China?

    Yu, Jie-Mei

    China CDC weekly

    2022  Volume 4, Issue 2, Page(s) 27–30

    Abstract: GII.2[P16] noroviruses (NoV) reemerged and rapidly became the main epidemic strain in acute gastroenteritis (AGE) outbreaks in Asian countries since 2016. The current GII.2 [P16] NoV showed the same antigenicity to the ones before 2016, but several ... ...

    Abstract GII.2[P16] noroviruses (NoV) reemerged and rapidly became the main epidemic strain in acute gastroenteritis (AGE) outbreaks in Asian countries since 2016. The current GII.2 [P16] NoV showed the same antigenicity to the ones before 2016, but several unique amino acid substitutions existed in the RNA dependent RNA polymerase (RdRp) and other non-structural proteins, and the viral load of the current GII.2[P16] NoV was higher than those of other genotypes, it was estimated that the viral replication ability may have improved. However, other genotypes, such as GII.1 and GII.3, also had recombination with the novel RdRp, were not prevalent in AGE-outbreaks; thus, it was inferred that the capsid proteins also played an important role in the enhanced replication process. The viral infection could also be affected by other factors, such as the population genetic background, the climate and environment, and people's lifestyles. Continued surveillance on genetic diversity and evolutionary pattern for the GII.2[P16] NoV is necessary.
    Language English
    Publishing date 2022-05-13
    Publishing country China
    Document type Journal Article
    ISSN 2096-7071
    ISSN (online) 2096-7071
    DOI 10.46234/ccdcw2022.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: The Regulatory Mechanism of Hypoxia-inducible Factor 1 and its Clinical Significance.

    Yin, Chun-Li / Ma, Yu-Jie

    Current molecular pharmacology

    2024  Volume 17, Page(s) e18761429266116

    Abstract: Hypoxia-inducible factor (HIF) is a nuclear protein that plays a crucial role in oxygen homeostasis through its transcriptional activity and thousands of target gene profiles. Through transcriptional and post-transcriptional regulation, the downstream ... ...

    Abstract Hypoxia-inducible factor (HIF) is a nuclear protein that plays a crucial role in oxygen homeostasis through its transcriptional activity and thousands of target gene profiles. Through transcriptional and post-transcriptional regulation, the downstream target genes of HIF can trigger multiple pathological responses in the body, including energy metabolism, cytopenia, and angiogenesis. There are three distinct subtypes of HIF: HIF-1, HIF-2, and HIF-3. HIF-1 is a significant regulator of the cellular response to hypoxia, and the balance between its production and degradation is critical for this response. As hypoxia is linked to several disorders, understanding HIF can open up novel avenues for the treatment of many diseases. This review describes the regulatory mechanisms of HIF-1 synthesis and degradation and the clinical significance of the hypoxia-inducible factor pathway in lung injury, kidney disease, hematologic disorders, and inflammation-related diseases.
    MeSH term(s) Humans ; Cell Hypoxia/physiology ; Clinical Relevance ; Gene Expression Regulation ; Hypoxia ; Hypoxia-Inducible Factor 1/genetics ; Hypoxia-Inducible Factor 1/metabolism
    Chemical Substances Hypoxia-Inducible Factor 1
    Language English
    Publishing date 2024-02-19
    Publishing country United Arab Emirates
    Document type Review ; Journal Article
    ISSN 1874-4702
    ISSN (online) 1874-4702
    DOI 10.2174/0118761429266116231123160809
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: [Degradation of Carbamazepine in Water by UV-activated Sulfite Process].

    Lin, Tao / Yuan, Yu-Jie

    Huan jing ke xue= Huanjing kexue

    2024  Volume 45, Issue 3, Page(s) 1553–1560

    Abstract: In this study, the degradation efficiency and mechanism of carbamazepine (CBZ), a typical emerging contaminant in water, in the UV/sulfite process were investigated. The effects of different concentrations of dissolved oxygen [ ...

    Abstract In this study, the degradation efficiency and mechanism of carbamazepine (CBZ), a typical emerging contaminant in water, in the UV/sulfite process were investigated. The effects of different concentrations of dissolved oxygen [
    MeSH term(s) Water ; Ultraviolet Rays ; Humic Substances ; Water Pollutants, Chemical/analysis ; Carbamazepine/analysis ; Kinetics ; Sulfites ; Sulfates ; Water Purification/methods ; Oxidation-Reduction
    Chemical Substances Water (059QF0KO0R) ; Humic Substances ; Water Pollutants, Chemical ; Carbamazepine (33CM23913M) ; Sulfites ; Sulfates
    Language Chinese
    Publishing date 2024-03-12
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 0250-3301
    ISSN 0250-3301
    DOI 10.13227/j.hjkx.202304213
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Tumor Vasculature as an Emerging Pharmacological Target to Promote Anti-Tumor Immunity.

    Tzeng, Hong-Tai / Huang, Yu-Jie

    International journal of molecular sciences

    2023  Volume 24, Issue 5

    Abstract: Tumor vasculature abnormality creates a microenvironment that is not suitable for anti-tumor immune response and thereby induces resistance to immunotherapy. Remodeling of dysfunctional tumor blood vessels by anti-angiogenic approaches, known as vascular ...

    Abstract Tumor vasculature abnormality creates a microenvironment that is not suitable for anti-tumor immune response and thereby induces resistance to immunotherapy. Remodeling of dysfunctional tumor blood vessels by anti-angiogenic approaches, known as vascular normalization, reshapes the tumor microenvironment toward an immune-favorable one and improves the effectiveness of immunotherapy. The tumor vasculature serves as a potential pharmacological target with the capacity of promoting an anti-tumor immune response. In this review, the molecular mechanisms involved in tumor vascular microenvironment-modulated immune reactions are summarized. In addition, the evidence of pre-clinical and clinical studies for the combined targeting of pro-angiogenic signaling and immune checkpoint molecules with therapeutic potential are highlighted. The heterogeneity of endothelial cells in tumors that regulate tissue-specific immune responses is also discussed. The crosstalk between tumor endothelial cells and immune cells in individual tissues is postulated to have a unique molecular signature and may be considered as a potential target for the development of new immunotherapeutic approaches.
    MeSH term(s) Humans ; Neovascularization, Pathologic/pathology ; Endothelial Cells/pathology ; Angiogenesis Inhibitors/therapeutic use ; Neoplasms/pathology ; Immunotherapy ; Tumor Microenvironment
    Chemical Substances Angiogenesis Inhibitors
    Language English
    Publishing date 2023-02-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24054422
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Barriers to Transportation in Rural Communities: Perspective of Older Adult Users.

    Yu, Jie / Liu, Yue

    The journals of gerontology. Series B, Psychological sciences and social sciences

    2023  Volume 79, Issue 1

    Abstract: Objectives: Rural older adults who require transportation assistance face more challenges than their urban counterparts. By focusing on a historically underserved population, this study examined specific barriers from the perspective of older adult ... ...

    Abstract Objectives: Rural older adults who require transportation assistance face more challenges than their urban counterparts. By focusing on a historically underserved population, this study examined specific barriers from the perspective of older adult users and explored potential policy and technology solutions.
    Methods: A cross-sectional study was conducted throughout rural Wisconsin to identify specific barriers to transportation, uncover personal factors associated with identified barriers, and measure causal relationships between identified barriers and travel satisfaction.
    Results: A total of 580 older adult respondents from 92% of rural counties across the state provided clear answers regarding specific transportation barriers. Of these, 67.6% identified at least one barrier, but only 12.8% had stopped using transportation due to any identified barriers. Top barriers to accessing transportation included service hours, service areas, trip destinations, getting in/out of service vehicles, service reservations, and operational scheduling. Although specific barriers were associated with different sociodemographics, trip purposes, and frequency of transportation usage, logistic regression findings suggested that concerns about service hours, service areas, and service reservation were the only 3 major determinants driving rural older adults' attitudes toward transportation usage.
    Discussion: Rural older adults relying on transportation assistance have demonstrated diverse needs and constraints. Rural transportation could provide better support by extending service availability in terms of hours, areas, and destinations, improving door-to-door accessibility by providing "arm through arm" services, enhancing service responsiveness and reliability via age-friendly technology solutions, and implementing a sliding scale subsidy program that takes income level and trip frequency into account.
    MeSH term(s) Humans ; Aged ; Health Services Accessibility ; Rural Population ; Cross-Sectional Studies ; Reproducibility of Results ; Transportation
    Language English
    Publishing date 2023-09-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1223664-0
    ISSN 1758-5368 ; 1079-5014
    ISSN (online) 1758-5368
    ISSN 1079-5014
    DOI 10.1093/geronb/gbad135
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: [Genetic analysis of a child with Hemoglobin Santa Ana].

    Liu, Jianghua / Yu, Jie

    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics

    2023  Volume 40, Issue 3, Page(s) 287–290

    Abstract: Objective: To explore the genetic basis for a child with Hemoglobin Santa Ana (Hb Santa Ana).: Methods: The child was admitted to the Children's Hospital of Chongqing Medical University on August 4, 2013 due to anemia, splenomegaly and deepening ... ...

    Abstract Objective: To explore the genetic basis for a child with Hemoglobin Santa Ana (Hb Santa Ana).
    Methods: The child was admitted to the Children's Hospital of Chongqing Medical University on August 4, 2013 due to anemia, splenomegaly and deepening urine color for 5 years. His clinical data were collected. Peripheral blood samples of the child and his parents were collected for routine blood test. The erythrocyte parameters of the child and his parents were determined with an automatic hemocyte analyzer. The hemoglobin components of the child and his parents were detected by high-performance liquid chromatography (HPLC). Common mutations associated with thalassemia were detected by Gap-PCR and PCR-reverse dot blotting (PCR-RDB). Rare variants of the globin genes were detected by next generation sequencing (NGS), and the result was verified by Sanger sequencing.
    Results: The child has shown mild to moderate hemolytic anemia. Routine blood test showed that he had lower hemoglobin (90 g/L) and mean corpuscular hemoglobin concentration (267 g/L) but a higher reticulocyte ratio (0.141), which indicated hypopigmented hyperplastic anemia. Analysis of hemoglobin component showed that his hemoglobin F was elevated to 10.7%, which indicated abnormal synthesis of β globin peptide chain. HPLC analysis showed an abnormal peak accounting for 4.5% of the total area. Neither of his parents was found to have abnormal results for routine blood test and hemoglobin component analysis. No common globin gene variant was detected in the child. Gene sequencing revealed that the child has harbored a heterozygous variant of HBB: c.266T>C, which was de novo in origin. Based on the guidelines of American College of Medical Genetics and Genomics, the variant was predicted to be pathogenic.
    Conclusion: The heterozygous HBB: c.266T>C variant probably underlay the hemolytic anemia associated with Hb Santa Ana in this patient.
    MeSH term(s) Child ; Humans ; Male ; Chromatography, High Pressure Liquid ; Hemoglobins, Abnormal/genetics
    Chemical Substances hemoglobin Santa Ana (37359-24-3) ; Hemoglobins, Abnormal
    Language Chinese
    Publishing date 2023-02-26
    Publishing country China
    Document type Case Reports ; English Abstract ; Journal Article
    ISSN 1003-9406
    ISSN 1003-9406
    DOI 10.3760/cma.j.cn511374-20220923-00619
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: Regulatory mechanisms triggered by enzyme interactions with lipid membrane surfaces.

    Yu, Jie / Boehr, David D

    Frontiers in molecular biosciences

    2023  Volume 10, Page(s) 1306483

    Abstract: Recruitment of enzymes to intracellular membranes often modulates their catalytic activity, which can be important in cell signaling and membrane trafficking. Thus, re-localization is not only important for these enzymes to gain access to their ... ...

    Abstract Recruitment of enzymes to intracellular membranes often modulates their catalytic activity, which can be important in cell signaling and membrane trafficking. Thus, re-localization is not only important for these enzymes to gain access to their substrates, but membrane interactions often allosterically regulate enzyme function by inducing conformational changes across different time and amplitude scales. Recent structural, biophysical and computational studies have revealed how key enzymes interact with lipid membrane surfaces, and how this membrane binding regulates protein structure and function. This review summarizes the recent progress in understanding regulatory mechanisms involved in enzyme-membrane interactions.
    Language English
    Publishing date 2023-11-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2023.1306483
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top