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  1. Book ; Thesis: The effect of proinflammatory cytokines on iRhom2, ADAM17 and CX3CL1 in lung

    Yu, Yan

    2022  

    Author's details vorgelegt von Yan Yu
    Language English
    Size IV, 68 Seiten, Illustrationen, Diagramme
    Publishing place Aachen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2022
    HBZ-ID HT021573377
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2023 D 56 order for loan Magazin

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  2. Book ; Online: Micronutrients in Maternal and Infant Health

    Yu, Yunxian

    Where We Are and Where We Should Go

    2023  

    Keywords Research & information: general ; Biology, life sciences ; Food & society ; gestational diabetes mellitus ; subtypes ; gene polymorphism ; vitamin D ; manganese ; cord blood ; birth outcomes ; childhood growth ; dietary pattern ; B vitamins ; pregnancy ; birth weight ; small-for-gestational-age ; reduced rank regression ; maternal hemoglobin concentration ; neonatal birth weight ; LBW ; SGA ; nonlinear association ; prospective study ; preeclampsia ; systematic review ; meta-analysis ; zinc ; copper ; selenium ; congenital heart defects ; vitamin E ; gestational diabetes mellitus (GDM) ; large-for-gestational-age (LGA) ; cord serum 25(OH)D level ; vitamin D deficiency ; urinary selenium ; repeated measurements ; SNPs ; hypertensive disorders of pregnancy ; prospective cohort study ; hemoglobin ; iron supplementary ; maternal hemoglobin ; neonatal ; SGA/LBW ; LGA/macrosomia ; passive smoking ; spontaneous abortion ; co-exposure ; Vitamin D ; deficiency ; thyroid-stimulating hormone ; free thyroxine ; free triiodothyronine ; vitamin A ; retinol ; human milk ; full-term infant ; lactation stage ; nickle ; trace elements ; restricted cubic spline ; LASSO regression ; quantile g-computation ; BKMR models ; n/a
    Language English
    Size 1 electronic resource (216 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030381982
    ISBN 9783036572734 ; 3036572732
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article: Emerging trends in clinical cancer genomic research.

    Yu, Yingyan

    Cancer biology & medicine

    2024  Volume 20, Issue 11

    MeSH term(s) Humans ; Neoplasms/genetics ; Neoplasms/therapy ; Genomics
    Language English
    Publishing date 2024-01-03
    Publishing country China
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2676322-9
    ISSN 2095-3941
    ISSN 2095-3941
    DOI 10.20892/j.issn.2095-3941.2023.0383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Convergence of Relative Entropy for Euler-Maruyama Scheme to Stochastic Differential Equations with Additive Noise.

    Yu, Yuan

    Entropy (Basel, Switzerland)

    2024  Volume 26, Issue 3

    Abstract: For a family of stochastic differential equations driven by additive Gaussian noise, we study the asymptotic behaviors of its corresponding Euler-Maruyama scheme by deriving its convergence rate in terms of relative entropy. Our results for the ... ...

    Abstract For a family of stochastic differential equations driven by additive Gaussian noise, we study the asymptotic behaviors of its corresponding Euler-Maruyama scheme by deriving its convergence rate in terms of relative entropy. Our results for the convergence rate in terms of relative entropy complement the conventional ones in the strong and weak sense and induce some other properties of the Euler-Maruyama scheme. For example, the convergence in terms of the total variation distance can be implied by Pinsker's inequality directly. Moreover, when the drift is β(0<β<1)-Hölder continuous in the spatial variable, the convergence rate in terms of the weighted variation distance is also established. Both of these convergence results do not seem to be directly obtained from any other convergence results of the Euler-Maruyama scheme. The main tool this paper relies on is the Girsanov transform.
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e26030232
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The Function of NK Cells in Tumor Metastasis and NK Cell-Based Immunotherapy.

    Yu, Yanlin

    Cancers

    2023  Volume 15, Issue 8

    Abstract: Metastatic tumors cause the most deaths in cancer patients. Treating metastasis remains the primary goal of current cancer research. Although the immune system prevents and kills the tumor cells, the function of the immune system in metastatic cancer has ...

    Abstract Metastatic tumors cause the most deaths in cancer patients. Treating metastasis remains the primary goal of current cancer research. Although the immune system prevents and kills the tumor cells, the function of the immune system in metastatic cancer has been unappreciated for decades because tumors are able to develop complex signaling pathways to suppress immune responses, leading them to escape detection and elimination. Studies showed NK cell-based therapies have many advantages and promise for fighting metastatic cancers. We here review the function of the immune system in tumor progression, specifically focusing on the ability of NK cells in antimetastasis, how metastatic tumors escape the NK cell attack, as well as the recent development of effective antimetastatic immunotherapies.
    Language English
    Publishing date 2023-04-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15082323
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Micronutrients in Maternal and Infant Health: Where We Are and Where We Should Go.

    Yu, Yunxian

    Nutrients

    2023  Volume 15, Issue 9

    Abstract: The first 1000 days of life are defined by the World Health Organization as a "window of opportunity" for a person's growth and development, and nutrition is particularly important during this time window [ ... ]. ...

    Abstract The first 1000 days of life are defined by the World Health Organization as a "window of opportunity" for a person's growth and development, and nutrition is particularly important during this time window [...].
    MeSH term(s) Infant ; Humans ; Infant Health ; Micronutrients ; Family ; Research ; Nutritional Status
    Chemical Substances Micronutrients
    Language English
    Publishing date 2023-05-05
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15092192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Evaluation on interactive waiting experience design of mobile internet products based on machine learning.

    Yu, Yi

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 16985

    Abstract: In today's rapidly changing economy, efficient lifestyle has become the current situation of most mobile product users. With the development of performance tools and technologies, a fast lifestyle has brought more wealth and opportunities to users. The ... ...

    Abstract In today's rapidly changing economy, efficient lifestyle has become the current situation of most mobile product users. With the development of performance tools and technologies, a fast lifestyle has brought more wealth and opportunities to users. The slow pace and fluctuating time are indirect income losses, which cause user anxiety to some extent. When the waiting time exceeds the user's waiting threshold, users would experience negative emotions, such as boredom, anxiety and anger, and product satisfaction would drop significantly. Therefore, by analyzing the uniqueness of mobile Internet products and the characteristics of users, this paper studied the reasons and influencing factors of product interactive waiting, and then used machine learning algorithm to analyze the cost function of interactive waiting experience. Finally, the corresponding interactive waiting experience design strategy was proposed. By comparison, the user experience after product interaction optimization design was 8.4% higher than that before product interaction optimization design, and the user frequency was also 14.7% higher after optimization design. In short, user experience plays an important role in product interaction design.
    Language English
    Publishing date 2023-10-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-43405-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Links between Sleep Apnoea and Insomnia in a British Cohort.

    Yu, Yizhou

    Clocks & sleep

    2023  Volume 5, Issue 3, Page(s) 552–565

    Abstract: Poor sleep is a major public health problem with implications for a wide range of critical health outcomes. Insomnia and sleep apnoea are the two most common causes of poor sleep, and recent studies have shown that these disorders frequently co-occur. ... ...

    Abstract Poor sleep is a major public health problem with implications for a wide range of critical health outcomes. Insomnia and sleep apnoea are the two most common causes of poor sleep, and recent studies have shown that these disorders frequently co-occur. Comorbid insomnia and sleep apnoea can substantially impair quality of life and increase the overall risk of mortality. However, the causal and physiological links between sleep apnoea and insomnia are unclear. It is also unknown whether having a higher risk for one condition can increase the risk of developing the other. Here, we investigated links between sleep apnoea and insomnia in a British population using a combination of self-reported questionnaires and causal inference. We found that 54.3% of the cohort had moderate insomnia, 9.4% had moderate sleep apnoea, and that 6.2% scored high for both conditions. Importantly, having a higher risk of sleep apnoea was associated with a higher risk of insomnia and vice versa. To determine the causal directionality between sleep apnoea and insomnia, we used Mendelian randomisation and found evidence that sleep apnoea could cause insomnia, but not the reverse. To elucidate how both sleep apnoea and insomnia were linked to each other, we looked at the behavioural markers of poor sleep. We found that feeling fatigued after sleeping and having noticeable sleep problems were linked to a higher burden of both sleep apnoea and insomnia. In conclusion, our results show that sleep apnoea increases the risk of developing insomnia, and both conditions can result in fatigue. We highlight the importance of considering and treating the symptoms of both conditions.
    Language English
    Publishing date 2023-09-11
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2624-5175
    ISSN (online) 2624-5175
    DOI 10.3390/clockssleep5030036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Academic success: don't forget our mental health.

    Yu, Yifan

    The Lancet. Child & adolescent health

    2023  Volume 8, Issue 1, Page(s) 14–16

    MeSH term(s) Humans ; Mental Health ; Academic Success ; Mental Disorders/therapy
    Language English
    Publishing date 2023-06-07
    Publishing country England
    Document type Journal Article
    ISSN 2352-4650
    ISSN (online) 2352-4650
    DOI 10.1016/S2352-4642(23)00325-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: BEND3 takes the rein.

    Yu, Yang

    Science China. Life sciences

    2023  Volume 66, Issue 5, Page(s) 1210–1212

    Language English
    Publishing date 2023-01-13
    Publishing country China
    Document type Journal Article
    ZDB-ID 2546732-3
    ISSN 1869-1889 ; 1674-7305
    ISSN (online) 1869-1889
    ISSN 1674-7305
    DOI 10.1007/s11427-022-2134-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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