Article: [Clinical Study of San Wei Sheng Huo Decoction in the Treatment of Refractory Chemotherapy-Induced Thrombocytopenia].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
2023 Volume 54, Issue 1, Page(s) 161–164
Abstract: Objective: To investigate the efficacy and safety of treating refractory chemotherapy-induced thrombocytopenia (RCIT) with San Wei Sheng Huo Decoction (SWSHD) as the main formula.: Methods: A retrospective study was conducted and the data of RCIT ... ...
| Abstract | Objective: To investigate the efficacy and safety of treating refractory chemotherapy-induced thrombocytopenia (RCIT) with San Wei Sheng Huo Decoction (SWSHD) as the main formula. Methods: A retrospective study was conducted and the data of RCIT patients treated with SWSHD as the main formula were collected. Changes in peripheral blood platelet (PLT) levels at different time points of treatment were examined and the significant effective rate (SER) and effective rate (ER) were analyzed. We measured the increase in peripheral blood PLT count before and after treatment, analyzed the differences in PLT count increase for different degrees of RCIT treatment, and evaluated the safety of the treatment. Results: A total of 35 cases of RCIT were included in the study. With SWSHD as the main treatment formula, the 2-week ER and SER were 74.29% and 14.29%, respectively, the 2-month ER and SER were 84.38% and 60.50, respectively, and the 1-year ER and SER were 92.31% and 80.77%, respectively. PLT count increased at all time points after treatment compared with that before treatment ( Conclusion: SWSHD takes effect rapidly and its effect is long-lasting and stable. Furthermore, SWSHD has a more significant effect on severe RCIT. |
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| MeSH term(s) | Humans ; Retrospective Studies ; Thrombocytopenia/chemically induced ; Thrombocytopenia/drug therapy ; Platelet Count ; Blood Platelets ; Antineoplastic Agents/adverse effects |
| Chemical Substances | Antineoplastic Agents |
| Language | Chinese |
| Publishing date | 2023-01-16 |
| Publishing country | China |
| Document type | English Abstract ; Journal Article |
| ZDB-ID | 2106840-9 |
| ISSN | 1672-173X |
| ISSN | 1672-173X |
| DOI | 10.12182/20230160506 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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