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  1. Article ; Online: Does Psychological Contract Violation Change the Original Intention of Eco-Tourists to Participate in Scenic Value Co-Creation?

    Hailing Liu / Ping Hu / Kewei Shi / Yudan Zhang

    Sustainability, Vol 15, Iss 4750, p

    2023  Volume 4750

    Abstract: Eco-tourists are the practitioners of promoting the harmonious development of humans and nature, and have a very important significance for the scenic spots and sustainable development of scenic areas. However, external factors often interfere with the ... ...

    Abstract Eco-tourists are the practitioners of promoting the harmonious development of humans and nature, and have a very important significance for the scenic spots and sustainable development of scenic areas. However, external factors often interfere with the eco-tourists’ original intention, which not only affect the tourist experience, but also bring a negative influence to the scenic spots, and even the destinations where they are located. Identifying the triggering factors and processes that influence eco-tourists’ participation in scenic value co-creation will lay a solid foundation for the effective governance of scenic areas. This paper systematically explores whether, how and when psychological contract violations significantly affect the eco-tourists’ participation in scenic value co-creation from the perspective of psychological contract violations. The data are collected from 556 eco-tourists’ questionnaires from the Yellow River Estuary Ecotourism Zone of Dongying City, Shandong Province, China. Through a hierarchical regression analysis and further validated by the Bootstrap method, the study finds the following: First, eco-tourists’ psychological contract violation has a significant negative effect on their participation in value co-creation. Second, moral disengagement plays a mediating role in the relationship between psychological contract violation and value co-creation behavior. Third, moral disengagement acts on value co-creation. The process of moral disengagement on value co-creation behavior is influenced by the level of expertise. The negative effect of moral disengagement on value co-creation decreases as the level of expertise increases. The findings of this paper not only expand the antecedents of tourists’ participation and the path of psychological contract violation in value co-creation, but also have important practical implications for promoting eco-tourists’ participation in value co-creation as well as reducing, preventing and identifying psychological contract violation in ecotourism ...
    Keywords eco-tourist ; psychological contract violation ; moral disengagement ; expertise ; value co-creation ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 910
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Spatiotemporal Heterogeneity of Urban Land Expansion and Urban Population Growth under New Urbanization

    Yudan Zhang / Yuanqing Li / Yanan Chen / Shirao Liu / Qingyuan Yang

    International Journal of Environmental Research and Public Health, Vol 19, Iss 7792, p

    A Case Study of Chongqing

    2022  Volume 7792

    Abstract: Land urbanization (LU) and population urbanization (PU) maintain the nature of spatiotemporal heterogeneity in China. As a municipality directly administered by the central government in the mode of “large cities and large rural areas”, Chongqing’s ... ...

    Abstract Land urbanization (LU) and population urbanization (PU) maintain the nature of spatiotemporal heterogeneity in China. As a municipality directly administered by the central government in the mode of “large cities and large rural areas”, Chongqing’s urbanization process is the epitome of China’s urbanization process. This paper examines the spatiotemporal variability of LU and PU in Chongqing on the basis of nighttime light data, the elasticity coefficient of the coupling relationship, and GWR. The results show that (1) the urban land and urban population in Chongqing grew notably from 2008 to 2018, with average annual growth rates of 9.4% and 2.3%, respectively. (2) The coupling coordination coefficient of LU and PU in Chongqing was 0.24, and the total number of districts and counties with uncoordinated development increased, but the overall uncoordinated situation gradually improved over the period. (3) The influence of PU on LU in each district and county increased year by year, and it showed a decreasing trend from southwest to northeast in Chongqing, which indicates that LU was increasingly adapted to the construction needs of PU. The gap between LU and PU widened due to the household registration system, land fiscal policies and other policies. After the reform of the household registration system and the adjustment of new pilot policies targeting the construction of new-type urbanization, the coupling relationship between LU and PU was gradually improving to the coordinated mode. The findings indicate that Chinese urban areas should adhere to the principle of new-type urbanization construction and carry out scientific land planning strategies, strictly controlling land expansion to promote the reasonable development of population growth.
    Keywords urban land expansion ; urban population growth ; spatiotemporal heterogeneity ; Chongqing ; Medicine ; R
    Subject code 710
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Effects of C/N ratio variation in swine biogas slurry on soil dissolved organic matter

    Lilong Yan / Cong Liu / Yudan Zhang / Shuang Liu / Ying Zhang

    Ecotoxicology and Environmental Safety, Vol 209, Iss , Pp 111804- (2021)

    Content and fluorescence characteristics

    2021  

    Abstract: Nutrient-rich biogas slurry shows favorable prospects for application as an organic fertilizer in farmland. At the same time, due to differing sources and treatment methods, the C/N ratio of biogas slurry varies greatly. The effect of differences in C/N ... ...

    Abstract Nutrient-rich biogas slurry shows favorable prospects for application as an organic fertilizer in farmland. At the same time, due to differing sources and treatment methods, the C/N ratio of biogas slurry varies greatly. The effect of differences in C/N of biogas slurry on soil organic matter properties remains unclear. In this experiment, pig farm biogas slurry differing in C/N (3, 6, 8.84 and 12) was applied instead of fertilizer. Fluorescence spectroscopy combined with parallel factor analysis and principal component analysis were used to determine dissolved organic carbon (DOC) and fluorescent dissolved organic matter (FDOM) in soil dissolved organic matter (DOM). The experimental results showed that the DOC and FDOM contents of soil could be significantly increased at the initial stage of biogas slurry application. Compared with CK, on the 60th day, biogas slurry with a C/N of 12 exhibited the greatest improvement in DOC, FDOM as well as for Component 1, Component 2 and Component 3 contents in soil FDOM, 40.93%, 66.25%, 65.35%, 40.47%, and 78.42% respectively. However, compared with the 0th day, by the 60th day, biogas slurry with a C/N of 8.84 exhibited the greatest decrease in Component 4 content in soil FDOM, 74.68%. Biogas slurry with a C/N of 8.84 exerted the greatest promotion effect on corn growth, the utilization and transformation of Component 4 by plants and microorganisms in the soil. And it showed the strongest improvement in the degree of FDOM humification in the soil, the humification index increased from 4.16 ± 0.17 to 4.92 ± 0.58, compared with CK. This study provided new insights for the utilization of biogas slurry with respect to soil physical and chemical properties and maize plant growth.
    Keywords Biogas slurry ; C/N ; DOM ; Fluorescence spectra ; Humification ; Environmental pollution ; TD172-193.5 ; Environmental sciences ; GE1-350
    Subject code 630
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: The interactive effects of non-alcoholic fatty liver disease and hemoglobin concentration in the first trimester on the development of gestational diabetes mellitus.

    Mengnan Li / Min Hu / Zhijing Yue / Yudan Zhang / Hailan Yang

    PLoS ONE, Vol 16, Iss 9, p e

    2021  Volume 0257391

    Abstract: Gestational diabetes mellitus (GDM) is associated with adverse perinatal and maternal outcomes. Epidemiological studies have reported that non-alcoholic fatty liver disease (NAFLD) and a high hemoglobin (Hb) concentration are risk factors for GDM in the ... ...

    Abstract Gestational diabetes mellitus (GDM) is associated with adverse perinatal and maternal outcomes. Epidemiological studies have reported that non-alcoholic fatty liver disease (NAFLD) and a high hemoglobin (Hb) concentration are risk factors for GDM in the middle trimester. However, no consistent conclusions have been reached, especially in Chinese pregnant women. A case-control study was conducted to better understand the associations between NAFLD and Hb concentration in the first trimester and the risk of GDM and their interactive effects. Multivariable logistic regression analysis and a cross-product term of Hb and steatosis were used to evaluate the associations between first trimester Hb concentration, steatosis, and GDM and their interactive effects. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using two-sided statistical tests at an alpha level of 0.05. For the study, 1,017 normal pregnant women, and 343 pregnant women diagnosed with GDM (25.22%) were recruited from the First Hospital of Shanxi Medical University, Shanxi Province, China. NAFLD-associated steatosis was found to be independent risk factors for developing GDM compared with grade 0 steatosis, with ORs of 1.98 (95% CI: 1.35-2.89) and 2.27 (95% CI:1.29-3.96), respectively. Meanwhile, a high Hb concentration was found to be a risk factor for developing GDM compared with the normal Hb concentration (OR = 1.88; 95% CI:1.24-2.83). The risk of developing GDM was more pronounced among pregnant women who had both high-grade steatosis and higher Hb concentrations during their first trimester (OR = 6.24; 95% CI: 1.81-23.66). However, we found no significant interactions between Hb concentration and steatosis grade. In conclusion, our study confirmed that a high Hb concentration and NAFLD-associated steatosis during the first trimester play important roles in predicting the risk of GDM in Chinese women. Future studies are required to verify the interactive effects between NAFLD-associated steatosis and Hb concentration.
    Keywords Medicine ; R ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: c-Jun as a one-way valve at the naive to primed interface

    Dongwei Li / Ling Luo / Lin Guo / Chuman Wu / Ran Zhang / Yuling Peng / Menghua Wu / Junqi Kuang / Yan Li / Yudan Zhang / Jun Xie / Wenxiu Xie / Rui Mao / Gang Ma / Xiuling Fu / Jiekai Chen / Andrew P. Hutchins / Duanqing Pei

    Cell & Bioscience, Vol 13, Iss 1, Pp 1-

    2023  Volume 16

    Abstract: Abstract Background c-Jun is a proto-oncogene functioning as a transcription factor to activate gene expression under many physiological and pathological conditions, particularly in somatic cells. However, its role in early embryonic development remains ... ...

    Abstract Abstract Background c-Jun is a proto-oncogene functioning as a transcription factor to activate gene expression under many physiological and pathological conditions, particularly in somatic cells. However, its role in early embryonic development remains unknown. Results Here, we show that c-Jun acts as a one-way valve to preserve the primed state and impair reversion to the naïve state. c-Jun is induced during the naive to primed transition, and it works to stabilize the chromatin structure and inhibit the reverse transition. Loss of c-Jun has surprisingly little effect on the naïve to primed transition, and no phenotypic effect on primed cells, however, in primed cells the loss of c-Jun leads to a failure to correctly close naïve-specific enhancers. When the primed cells are induced to reprogram to a naïve state, these enhancers are more rapidly activated when c-Jun is lost or impaired, and the conversion is more efficient. Conclusions The results of this study indicate that c-Jun can function as a chromatin stabilizer in primed EpiSCs, to maintain the epigenetic cell type state and act as a one-way valve for cell fate conversions.
    Keywords EpiSCs ; c-Jun ; Naïve to primed transition ; Primed to naïve transition ; Biotechnology ; TP248.13-248.65 ; Biology (General) ; QH301-705.5 ; Biochemistry ; QD415-436
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Development of immunoassays for multi-residue detection of small molecule compounds

    Xueyan Cui / Maojun Jin / Pengfei Du / Ge Chen / Chan Zhang / Yudan Zhang / Yong Shao / Jing Wang

    Food and Agricultural Immunology, Vol 29, Iss 1, Pp 638-

    2018  Volume 652

    Abstract: The small molecule compounds like pesticide, veterinary drug, bio-toxin, and heavy metal are widely found in animals, plants, soil, etc. Excessive compounds residues will have a bad influence on human health and the environment. Thus, it is extremely ... ...

    Abstract The small molecule compounds like pesticide, veterinary drug, bio-toxin, and heavy metal are widely found in animals, plants, soil, etc. Excessive compounds residues will have a bad influence on human health and the environment. Thus, it is extremely urgent that can detect the small molecules simultaneously. At present, many researches of simultaneous detection for small molecules using the method of an immunoassays have been reported thanks to its advantages of fast speed, simple operation, and high specificity. The small molecules have only one antigenic determinant, so the competitive immunoassay is the main method for small molecule compounds detection. In this paper, our main job is to describe the development of immunoassay for multi-residue detection of small molecule compounds and introduce three ways to complete the analysis of multi-residue immunoassay of small molecule compounds. We also summarize deficiencies and make an expectation of the immunoassays.
    Keywords small molecule compounds ; multi-residue ; immunoassays ; Agriculture (General) ; S1-972 ; Immunologic diseases. Allergy ; RC581-607
    Subject code 540
    Language English
    Publishing date 2018-01-01T00:00:00Z
    Publisher Taylor & Francis Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Development of immunoassays for multi-residue detection of small molecule compounds

    Cui, Xueyan / Maojun Jin / Pengfei Du / Ge Chen / Chan Zhang / Yudan Zhang / Yong Shao / Jing Wang

    Food and agricultural immunology. 2018 Jan. 1, v. 29, no. 1

    2018  

    Abstract: The small molecule compounds like pesticide, veterinary drug, bio-toxin, and heavy metal are widely found in animals, plants, soil, etc. Excessive compounds residues will have a bad influence on human health and the environment. Thus, it is extremely ... ...

    Abstract The small molecule compounds like pesticide, veterinary drug, bio-toxin, and heavy metal are widely found in animals, plants, soil, etc. Excessive compounds residues will have a bad influence on human health and the environment. Thus, it is extremely urgent that can detect the small molecules simultaneously. At present, many researches of simultaneous detection for small molecules using the method of an immunoassays have been reported thanks to its advantages of fast speed, simple operation, and high specificity. The small molecules have only one antigenic determinant, so the competitive immunoassay is the main method for small molecule compounds detection. In this paper, our main job is to describe the development of immunoassay for multi-residue detection of small molecule compounds and introduce three ways to complete the analysis of multi-residue immunoassay of small molecule compounds. We also summarize deficiencies and make an expectation of the immunoassays.
    Keywords animals ; heavy metals ; human health ; immunoassays ; pesticides ; plants (botany) ; soil ; toxins ; veterinary drugs
    Language English
    Dates of publication 2018-0101
    Size p. 638-652.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 1015019-5
    ISSN 1465-3443 ; 0954-0105
    ISSN (online) 1465-3443
    ISSN 0954-0105
    DOI 10.1080/09540105.2018.1428284
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Pd-catalyzed C–P coupling of heteroaryl boronic acid with H-phosphonate diester

    Geng, Zhiyue / Dapeng Zou / Jingya Li / Lu Zheng / Yangjie Wu / Yudan Zhang / Yusheng Wu

    Tetrahedron letters. 2016 July 20, v. 57

    2016  

    Abstract: We report herein a novel protocol to construct C–P bond from heteroaryl boronic acid with H-phosphonate diester under Pd–Ag catalyzed system without addition of base. This method, directly using commercial available heteroaryl boronic acid as the ... ...

    Abstract We report herein a novel protocol to construct C–P bond from heteroaryl boronic acid with H-phosphonate diester under Pd–Ag catalyzed system without addition of base. This method, directly using commercial available heteroaryl boronic acid as the starting material, provides a new way to synthesize a variety of useful heteroaryl phosphonates.
    Keywords catalysts ; chemical bonding ; chemical reactions ; chemical structure ; palladium ; phosphonates ; silver
    Language English
    Dates of publication 2016-0720
    Size p. 3063-3066.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 204287-3
    ISSN 1873-3581 ; 0040-4039
    ISSN (online) 1873-3581
    ISSN 0040-4039
    DOI 10.1016/j.tetlet.2016.05.038
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Bio-barcode detection technology and its research applications

    Yuanshang Wang / Maojun Jin / Ge Chen / Xueyan Cui / Yudan Zhang / Mingjie Li / Yun Liao / Xiuyuan Zhang / Guoxin Qin / Feiyan Yan / A.M. Abd El-Aty / Jing Wang

    Journal of Advanced Research, Vol 20, Iss , Pp 23-

    A review

    2019  Volume 32

    Abstract: With the rapid development of nanotechnology, the bio-barcode assay (BCA), as a new diagnostic tool, has been gradually applied to the detection of protein and nucleic acid targets and small-molecule compounds. BCA has the advantages of high sensitivity, ...

    Abstract With the rapid development of nanotechnology, the bio-barcode assay (BCA), as a new diagnostic tool, has been gradually applied to the detection of protein and nucleic acid targets and small-molecule compounds. BCA has the advantages of high sensitivity, short detection time, simple operation, low cost, good repeatability and good linear relationship between detection results. However, bio-barcode technology is not yet fully formed as a complete detection system, and the detection process in all aspects and stages is unstable. Therefore, studying the optimal reaction conditions, optimizing the experimental steps, exploring the multi-residue detection of small-molecule substances, and preparing immuno-bio-barcode kits are important research directions for the standardization and commercialization of BCA. The main theme of this review was to describe the principle of BCA, provide a comparison of its application, and introduce the single-residue and multi-residue detection of macromolecules and single-residue detection of small molecules. We also compared it with other detection methods, summarized its feasibility and limitations, expecting that with further improvement and development, the technique can be more widely used in the field of stable small-molecule and multi-residue detection. Keywords: Bio-barcode assay, Protein, Application, Multi-residue detection of macromolecules, Single-molecule single-residue detection
    Keywords Medicine (General) ; R5-920 ; Science (General) ; Q1-390
    Subject code 612
    Language English
    Publishing date 2019-11-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: A simple and sensitive competitive bio-barcode immunoassay for triazophos based on multi-modified gold nanoparticles and fluorescent signal amplification

    Zhang, Chan / A.M. Abd El-Aty / Ge Chen / Jing Wang / Maojun Jin / Pengfei Du / Ruixing Li / Xiaolin Cao / Xueyan Cui / Yudan Zhang / Zejun Jiang

    Analytica chimica acta. 2017,

    2017  

    Abstract: A simple and highly sensitive immunoassay based on a competitive binding and bio-barcode amplification was designed for detection of small molecules, triazophos. The gold nanoparticles (AuNPs) were modified with monoclonal antibodies and 6- ... ...

    Abstract A simple and highly sensitive immunoassay based on a competitive binding and bio-barcode amplification was designed for detection of small molecules, triazophos. The gold nanoparticles (AuNPs) were modified with monoclonal antibodies and 6-carboxyfluorescein labeled single-stranded thiol-oligonucleotides (6-FAM-SH-ssDNAs); the fluorescence of 6-FAM was quenched by AuNPs. Ovalbumin-linked haptens were coated on the bottom of microplate to compete with the triazophos in the sample for binding to the antibodies on the AuNP probes. The fluorescence intensity was inversely proportional to analyte concentration. Parameters of AuNP probes preparation and immune reaction were optimized. At the optimal conditions, the salting process was shortened to 1 h and 166 ± 9 ssDNAs were loaded onto a single AuNP. The competitive fluorescence bio-barcode immunoassay was performed on water, rice, cucumber, cabbage and apple samples. The linear range of the method was 0.01–20 μg L−1and the limit of detection (LOD) was 6 ng L−1. The recovery and relative standard deviations (RSDs) ranged from 85.0 to 110.3% and 9.4–17.4%, respectively. Good correlations were obtained between the results of the developed method and liquid chromatography-tandem mass spectrometry (LC-MS/MS). In conclusion, it is suggested that the competitive fluorescent bio-barcode immunoassay had the potential to be used as a sensitive method for detection of a variety of small molecules in various samples.
    Keywords analytical chemistry ; apples ; cabbage ; cucumbers ; detection limit ; fluorescence ; haptens ; immune response ; immunoassays ; liquid chromatography ; monoclonal antibodies ; nanogold ; rice ; salting ; single-stranded DNA ; statistical analysis ; tandem mass spectrometry ; triazophos
    Language English
    Size p. .
    Publishing place Elsevier B.V.
    Document type Article
    Note Pre-press version
    ZDB-ID 1483436-4
    ISSN 1873-4324 ; 0003-2670
    ISSN (online) 1873-4324
    ISSN 0003-2670
    DOI 10.1016/j.aca.2017.10.032
    Database NAL-Catalogue (AGRICOLA)

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