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Article: [The role of Müller cells in the formation and development of macular hole].

Liu, C Y / Zhang, X M / Yue, H F / Shi, Y X

Zhonghua yan ke za zhi] Chinese journal of ophthalmology

2023  Volume 59, Issue 11, Page(s) 948–953

Abstract: Müller cells are important glial cells in the retina, which play important roles in maintaining the stability of the retina by mechanical support, homeostasis, and physiological metabolism, as well as protecting photoreceptor cells and retinal pigment ... ...

Abstract Müller cells are important glial cells in the retina, which play important roles in maintaining the stability of the retina by mechanical support, homeostasis, and physiological metabolism, as well as protecting photoreceptor cells and retinal pigment epithelial cells. The degeneration and destruction of Müller cells are often accompanied by various retinal diseases, and the function of Müller cells is changed under pathological conditions. Based on the summary of the morphology, distribution and function of Müller cells, this article analyzes the different manifestations and changes of Müller cells in different stages of macular hole and the closely related mechanisms, aiming to clarify the role of Müller cells in the formation and development of macular hole and to provide reference for the prediction of disease progression and guidance of treatment.(This article was published ahead of print on the official website of Chinese Journal of Ophthalmology on Augest 28, 2023).
MeSH term(s) Humans ; Ependymoglial Cells ; Retinal Perforations ; Retina/pathology ; Photoreceptor Cells/physiology ; Retinal Diseases/pathology ; Neuroglia/pathology
Language Chinese
Publishing date 2023-08-28
Publishing country China
Document type English Abstract ; Journal Article
ZDB-ID 604574-1
ISSN 0412-4081
ISSN 0412-4081
DOI 10.3760/cma.j.cn112142-20230627-00246
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