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Article ; Online: The Nonlinear Relationship between Intellectual Property Protection and Farmers’ Entrepreneurship

Xinmin Liu / Yue Zheng / Wencheng Yu

Sustainability, Vol 15, Iss 6071, p

An Empirical Analysis Based on CHFS Data

2023 Volume 6071

Abstract: Using data from three rounds of the China Household Finance Survey (CHFS) in 2015, 2017 and 2019, this paper analyzes the impact and mechanism of the action of intellectual property protection on farm household entrepreneurship, based on institutional ... ...

Abstract	Using data from three rounds of the China Household Finance Survey (CHFS) in 2015, 2017 and 2019, this paper analyzes the impact and mechanism of the action of intellectual property protection on farm household entrepreneurship, based on institutional theory. It is found that: an inverted U-shaped relationship is shown between IPR protection and farm household entrepreneurship, but combined with the results of further research on farm household entrepreneurship performance, there is a positive effect of IPR protection and entrepreneurship performance. This indicates that excessive IPR protection, although limiting the number of entrepreneurship, boosts high-quality entrepreneurship; regional investment plays a mediating role between IPR protection and farm household entrepreneurship; and the results for IP protection and farmer opportunity entrepreneurship are the same as the baseline regression but have no significant effect on farmer initiative entrepreneurship, suggesting that IP protection more often increases farmers’ access to entrepreneurship. The above findings expand the application of “protecting intellectual property is protecting innovation” in farmers’ entrepreneurship and provide ideas for the implementation of intellectual property to promote, enrich and strengthen agriculture.
Keywords	intellectual property protection ; farmer entrepreneurship ; regional investment ; entrepreneurial performance ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	650
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: PHLPP1 inhibits the growth and aerobic glycolysis activity of human ovarian granular cells through inactivating AKT pathway

Xiaoyan Yang / Min A / Tana Gegen / Badema Daoerji / Yue Zheng / Aiming Wang

BMC Women's Health, Vol 24, Iss 1, Pp 1-

2024 Volume 10

Abstract: Abstract Background Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphologic features, and PCOS is associated with infertility. PH domain Leucine-rich repeat Protein ... ...

Abstract	Abstract Background Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphologic features, and PCOS is associated with infertility. PH domain Leucine-rich repeat Protein Phosphatase 1 (PHLPP1) has been shown to regulate AKT. The aim of present study is to investigate the role of PHLPP1 in PCOS. Methods The expression levels of PHLPP1 in dihydrotestosterone (DHT)-treated human ovarian granular KGN cells were determined by qRT-PCR and Western blot. PHLPP1 was silenced or overexpressed using lentivirus. Cell proliferation was detected by CCK-8. Apoptosis and ROS generation were analyzed by flow cytometry. Glycolysis was analyzed by measuring extracellular acidification rate (ECAR). Results DHT treatment suppressed proliferation, promoted apoptosis, enhanced ROS, and inhibited glycolysis in KGN cells. PHLPP1 silencing alleviated the DHT-induced suppression of proliferation and glycolysis, and promotion of apoptosis and ROS in KGN cells. PHLPP1 regulated cell proliferation and glycolysis in human KGN cells via the AKT signaling pathway. Conclusions Our results showed that PHLPP1 mediates the proliferation and aerobic glycolysis activity of human ovarian granular cells through regulating AKT signaling.
Keywords	PHLPP1 ; Infertility ; Polycystic ovary syndrome ; Glycolysis ; AKT signaling ; Gynecology and obstetrics ; RG1-991 ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Rare and complex diseases in focus

Yue Zheng / Xu Sun / Baijie Feng / Kai Kang / Yuqi Yang / Ailin Zhao / Yijun Wu

Frontiers in Artificial Intelligence, Vol

ChatGPT's role in improving diagnosis and treatment

2024 Volume 7

Abstract: Rare and complex diseases pose significant challenges to both patients and healthcare providers. These conditions often present with atypical symptoms, making diagnosis and treatment a formidable task. In recent years, artificial intelligence and natural ...

Abstract	Rare and complex diseases pose significant challenges to both patients and healthcare providers. These conditions often present with atypical symptoms, making diagnosis and treatment a formidable task. In recent years, artificial intelligence and natural language processing technologies have shown great promise in assisting medical professionals in diagnosing and managing such conditions. This paper explores the role of ChatGPT, an advanced artificial intelligence model, in improving the diagnosis and treatment of rare and complex diseases. By analyzing its potential applications, limitations, and ethical considerations, we demonstrate how ChatGPT can contribute to better patient outcomes and enhance the healthcare system's overall effectiveness.
Keywords	ChatGPT ; artificial intelligence ; rare and complex diseases ; diagnosis ; treatment ; Electronic computers. Computer science ; QA75.5-76.95
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Association Between Concerns About COVID-19 Infection and Blood Donation Intention

Qiuyue Hu / Wei Hu / Lingling Pan / Wenjuan Han / Yue Zheng

Journal of Medical Internet Research, Vol 25, p e

Cross-Sectional Survey Study Through a Mobile Communication Platform

2023 Volume 46588

Abstract: BackgroundThe ongoing COVID-19 pandemic has had an unprecedented impact on blood transfusion and collection. At the beginning of the pandemic, most blood transfusion services had a tough challenge in maintaining an optimal blood inventory. ObjectiveThis ... ...

Abstract	BackgroundThe ongoing COVID-19 pandemic has had an unprecedented impact on blood transfusion and collection. At the beginning of the pandemic, most blood transfusion services had a tough challenge in maintaining an optimal blood inventory. ObjectiveThis study aims to understand the public's psychological cognition and intention toward blood donation as well as the factors influencing their worries. We aimed to find a solution for increasing blood donations and provide a scientific reference for policy formulation regarding blood donation during the COVID-19 pandemic and in the future. MethodsA random survey with a 14-item scale on worries related to blood donation was conducted from December 31, 2022, to January 3, 2023, among residents aged 18-60 years in Zhejiang province via SMS text messaging. The results of 8 worry items in this study were compared with the survey results of March 2022, during which COVID-19 was not considered as an epidemic in Zhejiang province. Chi-square test and logistic regression analysis were performed to analyze the factors affecting respondents’ blood donation intention and concerns. The degree of worry about blood donation was assigned from 1 (completely disagree) to 5 (completely agree), and 2-sided t tests were performed to analyze the differences in blood donation intention and worries about blood donation. ResultsIn total, 1254 valid questionnaire responses were obtained. Males accounted for 62.36% (782/1254) of the sample, 78.39% (983/1254) were 18-45 years old, 60.61% (760/1254) had a university education, and 69.06% (866/1254) had no previous blood donation experience. Approximately 36.52% (458/1254) of the public clearly expressed that they had blood donation worries regarding COVID-19. The main concerns of the respondents were temporary physical weakness caused by blood donation, their own physical conditions not meeting the requirements of blood donation, inconvenient location and working hours for blood donation, and family (or friends) worrying about blood donation. ...
Keywords	Computer applications to medicine. Medical informatics ; R858-859.7 ; Public aspects of medicine ; RA1-1270
Subject code	610
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	JMIR Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Colonic mucosal biopsy location can not affect the results of mucosal metabolomics and mucosal microbiota analysis in IBS

Huiting Zhu / Yanli Zhang / Shiyu Du / Huifen Wang / Yue Zheng

Frontiers in Medicine, Vol

2023 Volume 10

Abstract: ObjectiveTo compare and analyze the mucosal metabolites and mucosal microbiota of different parts of colon in patients with IBS.MethodsA total of 10 patients with IBS-D and six healthy controls (HC) were enrolled. All enrolled participants underwent two ... ...

Abstract	ObjectiveTo compare and analyze the mucosal metabolites and mucosal microbiota of different parts of colon in patients with IBS.MethodsA total of 10 patients with IBS-D and six healthy controls (HC) were enrolled. All enrolled participants underwent two biopsies of the ileocecal and sigmoid colon during colonoscopy. Metabolomic profiling of one piece of tissue was conducted using desorption electrospray ionization-mass spectrometry (DESI-MS), and the gut flora of the other piece was examined using 16S rRNA sequencing. The metabolic profiles and flora of the ileocecal and sigmoid colonic mucosa in each group were further analyzed in this study.Results(1) Principal components analysis (PCA) indicated that mucosal metabolites did not differ in different parts of the colon in either the IBS-D or HC groups. (2) In the mucosal microbiome analyses, no differences between the microbiota of the two parts of the colon were found by using Principal Co-ordinates Analysis (PCoA). In IBS group, comparing with sigmoid mucosa, the chao1 richness indice was higher and the Shannon index was lower in the ileocecal mucosa (p = 0.40, p = 0.22). However, in the HC group, microbiome analysis of the ileocecal mucosa showed lower values for Chao 1 and Shannon indices than those of the sigmoid colon mucosa (p = 0.06, p = 0.86). (3) Compared with the HC group, 1,113 metabolic signal peaks were upregulated, whereas 594 metabolites were downregulated in the IBS-D samples. Moreover, the PCA of the metabolites showed significant separation between the IBS-D and HC groups. (4) Chao1 expression was significantly higher in the mucosal microbiota with IBS-D than in the HC (p = 0.03). The Shannon index was lower in IBS-D, but the difference was not statistically significant (p = 0.53). PCoA revealed a significant difference in the microflora structure between the IBS-D and HC groups.ConclusionThe mucosal metabolic profile and mucosal flora structure of the colon were similar, despite different locations in IBS and healthy subjects. IBS had ...
Keywords	irritable bowel syndrome ; ileocecal mucosa ; sigmoid ; metabolomics ; microbiota ; lipid ; Medicine (General) ; R5-920
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effects of sports intervention on aggression in children and adolescents

Yahui Yang / Hao Zhu / Kequn Chu / Yue Zheng / Fengshu Zhu

PeerJ, Vol 11, p e

a systematic review and meta-analysis

2023 Volume 15504

Abstract: Objective To explore the impact of sports on aggression in children and adolescents and analyze whether different conditions in the intervention, such as type of sports, or intervention duration, have different influences on the effect of interventions. ... ...

Abstract	Objective To explore the impact of sports on aggression in children and adolescents and analyze whether different conditions in the intervention, such as type of sports, or intervention duration, have different influences on the effect of interventions. Method The study protocol was registered in PROSPERO (CRD42022361024). We performed a systematic search of Pubmed, Web of Science, Cochrane library, Embase and Scopus databases from database inception to 12 October 2022 for all studies written in English. Studies were included if they met the following PICO criteria. All analyses were carried out using the Review Manager 5.3 Software. We summarized aggression, hostility and anger scores using SMDs. Summary estimates with 95% confidence intervals were pooled using DerSimonian-Laird random effects model or fixed effects model according to between-study heterogeneity. Results A total of 15 studies were deemed eligible for inclusion in this review. The overall mean effect size indicated that sport interventions was associated with lower aggression (SMD = −0.37, 95% CI [−0.69 to −0.06], P = 0.020; I2 = 88%). Subgroup analyses showed that non-contact sports were associated with lower aggression (SMD = −0.65, 95% CI [−1.17 to −0.13], P = 0.020; I2 = 92%) but high-contact sports were not (SMD = −0.15, 95% CI [−0.55 to 0.25], P = 0.470; I2 = 79%). In addition, when intervention duration <6 months, sport interventions was associated with lower aggression (SMD = −0.99, 95% CI [−1.73 to −0.26], P = 0.008; I2 = 90%) and when intervention duration ≥ 6 months, sport interventions was not associated with lower aggression (SMD = −0.08, 95% CI [−0.44 to −0.28], P = 0.660; I2 = 87%). Conclusion This review confirmed that sports intervention can reduce the aggression of children and adolescents. We suggested that schools can organize young people to participate in low-level, non-contact sports to reduce the occurrence of bullying, violence and other aggression-related adverse events. Additional studies are needed to determine ...
Keywords	Sports ; Aggression ; Child ; Adolescent ; Meta-Analysis ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	796
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Spirobifluorene Mediating the Spin-Spin Coupling of Nitronyl Nitroxide Diradicals.

Yue, Zheng / Liu, Jin / Baumgarten, Martin / Wang, Di

The journal of physical chemistry. A

2023 Volume 127, Issue 7, Page(s) 1565–1575

Abstract: To investigate the mechanism of this spiro conjugation magnetic behavior, we designed and synthesized three diradicals─ ...

Abstract	To investigate the mechanism of this spiro conjugation magnetic behavior, we designed and synthesized three diradicals─
Language	English
Publishing date	2023-01-10
Publishing country	United States
Document type	Journal Article
ISSN	1520-5215
ISSN (online)	1520-5215
DOI	10.1021/acs.jpca.2c06648
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Elastic Correlative Least-Squares Reverse Time Migration Based on Wave Mode Decomposition

Yue Zheng / Youshan Liu / Tao Xu / Zhiyuan Li

Processes, Vol 10, Iss 288, p

2022 Volume 288

Abstract: The conventional elastic least-squares reverse time migration (LSRTM) generally inverts the parameter perturbation of the model rather than the reflectivity of reflected P- and S-modes, which leads to difficulty in directly interpreting the physical ... ...

Abstract	The conventional elastic least-squares reverse time migration (LSRTM) generally inverts the parameter perturbation of the model rather than the reflectivity of reflected P- and S-modes, which leads to difficulty in directly interpreting the physical properties of the subsurface media. However, an accurate velocity model that is needed by the separation of seismic records of conventional LSRTM is usually unavailable in real data, which limits its application. In this study, we introduce a new practical correlative LSRTM (CLSRTM) scheme based on wave mode decomposition without amplitude and phase distortion, which frees from separation of seismic records. In this study, we deduced the migration and the de-migration operators using the decoupled P- and S-wave equations in heterogeneous media, which needs no extra wavefield decomposition in simulated data. To accelerate the convergence and improve the efficiency of the inversion, we adopted an analytical step-length formula that can be incidentally computed during the necessary de-migration process and the L-BFGS algorithm. Two numerical examples demonstrate that the proposed method can compensate the energy of deep structures, and generate clear images with balanced amplitudes and enhanced resolution even for the fault structures beneath the salt dome.
Keywords	reverse time migration ; least-squares migration ; wave mode decomposition ; reflectivity ; heterogeneous ; Chemical technology ; TP1-1185 ; Chemistry ; QD1-999
Subject code	535
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Recent Progress on Vanadium Dioxide Nanostructures and Devices

Yanqing Zhang / Weiming Xiong / Weijin Chen / Yue Zheng

Nanomaterials, Vol 11, Iss 2, p

Fabrication, Properties, Applications and Perspectives

2021 Volume 338

Abstract: Vanadium dioxide (VO 2 ) is a typical metal-insulator transition (MIT) material, which changes from room-temperature monoclinic insulating phase to high-temperature rutile metallic phase. The phase transition of VO 2 is accompanied by sudden changes in ... ...

Abstract	Vanadium dioxide (VO 2 ) is a typical metal-insulator transition (MIT) material, which changes from room-temperature monoclinic insulating phase to high-temperature rutile metallic phase. The phase transition of VO 2 is accompanied by sudden changes in conductance and optical transmittance. Due to the excellent phase transition characteristics of VO 2 , it has been widely studied in the applications of electric and optical devices, smart windows, sensors, actuators, etc. In this review, we provide a summary about several phases of VO 2 and their corresponding structural features, the typical fabrication methods of VO 2 nanostructures (e.g., thin film and low-dimensional structures (LDSs)) and the properties and related applications of VO 2 . In addition, the challenges and opportunities for VO 2 in future studies and applications are also discussed.
Keywords	vanadium dioxide ; nanostructures ; metal-insulator phase transition ; fabrication methods ; properties and related applications ; Chemistry ; QD1-999
Subject code	620
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Mapping Building-Based Spatiotemporal Distributions of Carbon Dioxide Emission

Yue Zheng / Jinpei Ou / Guangzhao Chen / Xinxin Wu / Xiaoping Liu

International Journal of Environmental Research and Public Health, Vol 19, Iss 5986, p

A Case Study in England

2022 Volume 5986

Abstract: The spatiotemporal inventory of carbon dioxide (CO 2 ) emissions from the building sector is significant for formulating regional and global warming mitigation policies. Previous studies have attempted to use energy consumption models associated with ... ...

Abstract	The spatiotemporal inventory of carbon dioxide (CO 2 ) emissions from the building sector is significant for formulating regional and global warming mitigation policies. Previous studies have attempted to use energy consumption models associated with field investigations to estimate CO 2 emissions from buildings at local scales, or they used spatial proxies to downscale emission sources from large geographic units to grid cells for larger scales. However, mapping the spatiotemporal distributions of CO 2 emissions on a large scale based on buildings remains challenging. Hence, we conducted a case study in England in 2015, wherein we developed linear regression models to analyze monthly CO 2 emissions at the building scale by integrating the Emissions Database for Global Atmospheric Research, building data, and Visible Infrared Imaging Radiometer Suite night-time lights images. The results showed that the proposed model that considered building data and night-time light imagery achieved the best fit. Fine-scale spatial heterogeneity was observed in the distributions of building-based CO 2 emissions compared to grid-based emission maps. In addition, we observed seasonal differences in CO 2 emissions. Specifically, buildings emitted significantly more CO 2 in winter than in summer in England. We believe our results have great potential for use in carbon neutrality policy making and climate monitoring.
Keywords	CO 2 emissions ; linear regression analysis ; radiance-calibrated nightlight ; building-based ; Medicine ; R
Subject code	690
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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