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Article ; Online: Biomonitoring and health risk assessment of exposure to phthalate esters in waste management workers.

Janjani, Hosna / Rastkari, Noushin / Yousefian, Fatemeh / Aghaei, Mina / Yunesian, Masud

2024 Volume 180, Page(s) 76–84

Abstract: Humans are at risk of exposure to phthalates due to the widespread use of plasticized plastics, and one of the major concerns is occupational exposure. The present study investigated occupational exposure to phthalates at one of the greatest solid waste ... ...

Abstract	Humans are at risk of exposure to phthalates due to the widespread use of plasticized plastics, and one of the major concerns is occupational exposure. The present study investigated occupational exposure to phthalates at one of the greatest solid waste management sites in the second-largest country in the Middle East. Carcinogenic and non-carcinogenic health risks were assessed by human biomonitoring (HBM). The concentration of phthalate esters was determined using gas chromatography-mass spectrometry (GC-MS), and the daily intake (DI) of phthalate was calculated based on the adjusted urinary creatinine concentrations. Moreover, carcinogenic and non-carcinogenic risks were assessed. Monte Carlo simulations were performed for uncertainty and sensitivity analysis. The highest concentration recorded was 130.80 µg/g creatinine for mono-ethyl phthalate (MEP) among the composting group, while the lowest concentration was 0.49 µg/g creatinine for Monobenzyl phthalate (MBzP) among the office group. All estimates of daily intake were below the reference concentration, and differences between the DI at site sections were statistically significant (p < 0.05). The non-carcinogenic risk level was negligible. The excess lifetime cancer risk (ELCR) values corresponding to di-(2-ethylhexyl) phthalate (DEHP) exposure were 2.07E-04 among the composting group and 2.07E-04 among the processing group, posing a definite risk. The carcinogenic risk value among the office group was in a possible risk category with ELCR values of 9.75 E-05. The on-site workers of waste management sites can be highly exposed to phthalates, and their health risk is considerable. Appropriate measures and interventions should be considered to reduce occupational exposure to phthalates.
MeSH term(s)	Humans ; Environmental Exposure/analysis ; Environmental Pollutants/urine ; Biological Monitoring ; Creatinine/urine ; Phthalic Acids/urine ; Risk Assessment
Chemical Substances	phthalic acid (6O7F7IX66E) ; Environmental Pollutants ; Creatinine (AYI8EX34EU) ; Phthalic Acids
Language	English
Publishing date	2024-03-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2001471-5
ISSN	1879-2456 ; 0956-053X
ISSN (online)	1879-2456
ISSN	0956-053X
DOI	10.1016/j.wasman.2024.03.017
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Article ; Online: Comment on: "Pollution profiles of antibiotic resistance genes associated with airborne opportunistic pathogens from typical area, pearl river estuary and their exposure risk to human".

Aghaei, Mina / Yunesian, Masud

Environment international

2021 Volume 153, Page(s) 106554

MeSH term(s)	Anti-Bacterial Agents/toxicity ; Drug Resistance, Microbial/genetics ; Estuaries ; Geologic Sediments ; Humans ; Rivers
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2021-04-09
Publishing country	Netherlands
Document type	Letter ; Comment
ZDB-ID	554791-x
ISSN	1873-6750 ; 0160-4120
ISSN (online)	1873-6750
ISSN	0160-4120
DOI	10.1016/j.envint.2021.106554
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Article ; Online: Serum concentration of polychlorinated biphenyls and the risk of type 2 diabetes: a 10-year follow-up historical cohort study.

Ravanipour, Masoumeh / Nabipour, Iraj / Yunesian, Masud / Rastkari, Noushin / Mahvi, Amir Hossein

Scientific reports

2024 Volume 14, Issue 1, Page(s) 8562

Abstract: This study investigated the association between serum concentrations of Polychlorinated Biphenyls (PCBs) and the risk of type 2 diabetes within the general population. A ten-year follow-up historical cohort study was conducted during 2009-2019 as part of ...

Abstract	This study investigated the association between serum concentrations of Polychlorinated Biphenyls (PCBs) and the risk of type 2 diabetes within the general population. A ten-year follow-up historical cohort study was conducted during 2009-2019 as part of the Bushehr MONICA cohort study in Iran. Of 893 non-diabetes participants at base line, 181 individuals were included in the study. The concentration of nine PCB congeners was measured in individuals' serum samples at baseline, and the risk of type 2 diabetes was determined based on fasting blood sugar at the end of follow-up. Multiple logistic regression models were used to assess the study outcomes after adjusting for covariates. This study included 59 diabetes individuals (32.6%; mean [SD] age: 58.64 [8.05]) and 122 non-diabetes individuals (67.4%; mean [SD] age: 52.75 [8.68]). Multivariable analysis revealed that a one-tertile increase (increasing from 33rd centile to 67th centile) in Σ non-dioxin-like-PCBs (OR 2.749, 95% CI 1.066-7.089), Σ dioxin-like-PCBs (OR 4.842, 95% CI 1.911-12.269), and Σ PCBs (OR 2.887, 95% CI 1.120-7.441) significantly associated with an increased risk of type 2 diabetes. The strongest association was obtained for dioxin-like PCBs. The results highlight a significant correlation between PCB exposure and an increased risk of type 2 diabetes. The evidence suggests that additional epidemiological studies are necessary to clarify the link between PCBs and diabetes.
MeSH term(s)	Humans ; Middle Aged ; Diabetes Mellitus, Type 2/epidemiology ; Polychlorinated Biphenyls ; Cohort Studies ; Dioxins ; Follow-Up Studies ; Polychlorinated Dibenzodioxins
Chemical Substances	Polychlorinated Biphenyls (DFC2HB4I0K) ; Dioxins ; Polychlorinated Dibenzodioxins
Language	English
Publishing date	2024-04-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-59308-9
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Article ; Online: A supportive randomized clinical trial on Iranian infertile women with the history of infertility treatments dropout following unsuccessful ART cycle/s: A study protocol

Ghorbani, Maryam / Hoseini, Fatemeh Sadat / yunesian, Masud / Salehin, Shahrbanoo / Talebi, Seyedeh Solmaz / Keramat, Afsaneh

Heliyon. 2023 Mar., v. 9, no. 3 p.e13838-

2023

Abstract: Due to high dropout rate of infertility treatments and lack of any intervention for motivating infertile couples to continue treatments, the present study will be conducted with the aim of designing, implementing and determining the effectiveness of the ... ...

Abstract	Due to high dropout rate of infertility treatments and lack of any intervention for motivating infertile couples to continue treatments, the present study will be conducted with the aim of designing, implementing and determining the effectiveness of the proposed intervention in order to continue infertility treatments. & Analysis: We will conduct this study in two stages; a review of literature and past studies will be done to identify interventions that have been performed for infertile couples, and then an appropriate intervention with the aim of continuing infertility treatments for infertile women will be designed. After that a Delphi study will be designed in accordance with collected information of previous stages and will be approved by experts. In the second stage we will implement designed intervention of a randomized clinical trial on two groups of infertile women (control and intervention) with the history of infertility treatment dropout following unsuccessful cycle. We will use descriptive statistic in first and second stage. In second stage Chi square test and independent samples T test will be used to compare variables between groups and variables in study questionnaires before and after the intervention between two groups of study. The present study will be the first study to be performed as a clinical trial on infertile women who have discontinued the treatments, with the aim of continuing treatments. Thereupon, it seems that the results of this study will be the basis for studies around the world to prevent premature cessation of infertility treatments.
Keywords	chi-square distribution ; descriptive statistics ; randomized clinical trials ; t-test ; Infertility ; Dropout ; Intervention ; Randomized clinical trial
Language	English
Dates of publication	2023-03
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e13838
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Article: A supportive randomized clinical trial on Iranian infertile women with the history of infertility treatments dropout following unsuccessful ART cycle/s: A study protocol.

Ghorbani, Maryam / Hoseini, Fatemeh Sadat / Yunesian, Masud / Salehin, Shahrbanoo / Talebi, Seyedeh Solmaz / Keramat, Afsaneh

Heliyon

2023 Volume 9, Issue 3, Page(s) e13838

Abstract: Introduction: Due to high dropout rate of infertility treatments and lack of any intervention for motivating infertile couples to continue treatments, the present study will be conducted with the aim of designing, implementing and determining the ... ...

Abstract	Introduction: Due to high dropout rate of infertility treatments and lack of any intervention for motivating infertile couples to continue treatments, the present study will be conducted with the aim of designing, implementing and determining the effectiveness of the proposed intervention in order to continue infertility treatments. Methods: & Analysis: We will conduct this study in two stages; a review of literature and past studies will be done to identify interventions that have been performed for infertile couples, and then an appropriate intervention with the aim of continuing infertility treatments for infertile women will be designed. After that a Delphi study will be designed in accordance with collected information of previous stages and will be approved by experts Discussion: The present study will be the first study to be performed as a clinical trial on infertile women who have discontinued the treatments, with the aim of continuing treatments. Thereupon, it seems that the results of this study will be the basis for studies around the world to prevent premature cessation of infertility treatments.
Language	English
Publishing date	2023-02-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e13838
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Article ; Online: Burden of diseases attributable to second-hand smoke exposure in Iran adolescents from 2009 to 2020.

Janjani, Hosna / Nabizadeh, Ramin / Shamsipour, Mansour / Kashani, Homa / Aghaei, Mina / Yunesian, Masud

Scientific reports

2023 Volume 13, Issue 1, Page(s) 13605

Abstract: Exposure to second-hand smoke (SHS) is prevalent in many countries, but the problem's scope is poorly understood globally, especially in developing countries. We aimed to estimate SHS exposure and its national and subnational burden of diseases in Iran, ... ...

Abstract	Exposure to second-hand smoke (SHS) is prevalent in many countries, but the problem's scope is poorly understood globally, especially in developing countries. We aimed to estimate SHS exposure and its national and subnational burden of diseases in Iran, the second-largest country in the Middle East, during 2009-2020. The burden of diseases from SHS was estimated as disability-adjusted life years (DALYs) for adolescents (10-18) year's non-smokers. Using comparative risk assessment methodologies, the calculations were based on disease-specific relative risk estimates with national and subnational SHS exposure data, and the uncertainty and sensitivity analysis was performed. The results of study showed that the trend of exposure to SHS is increasing in Iran. The highest DALY was related to lower respiratory infection (LRI), asthma, and otitis media, respectively. The national average asthma burden (DALY/100,000) has increased from 17.4 (11.8_23.9) in 2009 to 21.3 (13.9_30) in 2020, LRI decreased from 25.8 (21.5_30.2) to 19.8 (16.7_23.1), and national average burden of otitis media (DALY/100,000) has increased from 3.1(1.9_4.6) to 3.9(2.4_5.6). The increasing trend of otitis media and asthma DALYs attributable to SHS exposure in Iran requires more attention from policymakers to protect the population.
MeSH term(s)	Adolescent ; Humans ; Iran/epidemiology ; Tobacco Smoke Pollution/adverse effects ; Middle East ; Asthma ; Respiratory Tract Infections ; Cost of Illness
Chemical Substances	Tobacco Smoke Pollution
Language	English
Publishing date	2023-08-21
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-40058-z
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Article ; Online: Designing and implementing an OMMID midwifery professional competence mixed test: A multimethod, multiphasic study.

Khajehpour, Mahin / Keramat, Afsaneh / Nahidi, Fatemeh / Yunesian, Masud / Fardid, Mozhgan / Goli, Shahrbanoo

Midwifery

2023 Volume 126, Page(s) 103831

Abstract: The assessment of professional competence is essential to ensure the achievement of competence standards. The goal of this study is to design and implement a professional competence test model to make the test unified, comprehensive, and fair. This ... ...

Abstract	The assessment of professional competence is essential to ensure the achievement of competence standards. The goal of this study is to design and implement a professional competence test model to make the test unified, comprehensive, and fair. This research was a multimethod, multiphasic study. The first qualitative phase of the nominal group technique was conducted to design the test model with specific guidelines. The second phase was a mixed-method parallel field trial conducted on 161 senior midwifery bachelor students in universities of Iran. The test was conducted following the traditional method in the control group and OMMID model in the intervention group. This model consists of three parts: the MCQs (multiple choice questions), OSCE (objective structured clinical examination), and clinically-oriented tests, which included Mini-CEX (mini-clinical evaluation exercise) and DOPS (direct observation of procedural skills). Data were collected using questionnaires and interviews, and the results were assessed qualitatively and quantitatively. The OMMID model and the associated guideline were designed. Qualitative data analysis resulted in six main themes, including organizing, structure, tension due to change, fairness, unification, and outcome. The OMMID model did not increase students' anxiety and stress and did not decrease their satisfaction. The merits of this model include having a centralized guideline, using multiple evaluation methods, comprehensive evaluation of necessary skills, promotion of fairness, and increased student satisfaction.
MeSH term(s)	Pregnancy ; Humans ; Female ; Clinical Competence ; Educational Measurement/methods ; Midwifery/education ; Professional Competence ; Students, Nursing
Language	English
Publishing date	2023-09-20
Publishing country	Scotland
Document type	Journal Article
ZDB-ID	1036567-9
ISSN	1532-3099 ; 0266-6138
ISSN (online)	1532-3099
ISSN	0266-6138
DOI	10.1016/j.midw.2023.103831
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Article ; Online: BTEX in indoor air of barbershops and beauty salons: Characterization, source apportionment and health risk assessment.

Janjani, Hosna / Yunesian, Masud / Yaghmaeian, Kamyar / Aghaei, Mina / Yousefian, Fatemeh / Alizadeh, Bahram / Fazlzadeh, Mehdi

Chemosphere

2023 Volume 345, Page(s) 140518

Abstract: Background: Volatile organic compounds, mainly BTEX, are among the pollutants of concern in beauty salons and barbershops that threaten both staff personnel and clients' health. This study aimed to determine the concentration of BTEX in barbershops and ... ...

Abstract	Background: Volatile organic compounds, mainly BTEX, are among the pollutants of concern in beauty salons and barbershops that threaten both staff personnel and clients' health. This study aimed to determine the concentration of BTEX in barbershops and beauty salons and assess the carcinogenic and non-carcinogenic risks based on the actual risk coefficients. Also, possible sources of BTEX were determined. Method: Samples were collected by passive sampling. Quantitative and qualitative measurements of BTEX compounds were performed using gas chromatography-mass spectrometry (GC-MASS). Subsequently, the health risks were assessed according to the US Environmental Protection Agency. SPSS24 software and positive matrix factorization (PMF) analysis were used for statistical analysis and source apportionment respectively. Results: Toluene is the most abundant compound in beauty salons, with a maximum concentration of 219.4 (μg/m Conclusion: Use of solvents and cosmetic products, improper heating systems, and type of service are the sources that probably contribute to BTEX emissions in beauty salons. It is necessary to follow health guidelines and conduct continuous monitoring for their implementation, in addition to setting a mandated occupational regulation framework or air quality requirements, to improve the health conditions in beauty salons.
MeSH term(s)	Male ; Female ; Humans ; Benzene/analysis ; Xylenes/analysis ; Air Pollutants/analysis ; Environmental Monitoring/methods ; Air Pollution, Indoor/analysis ; Benzene Derivatives/analysis ; Toluene/analysis ; Risk Assessment
Chemical Substances	Benzene (J64922108F) ; Xylenes ; Air Pollutants ; Benzene Derivatives ; Toluene (3FPU23BG52)
Language	English
Publishing date	2023-10-25
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2023.140518
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Article ; Online: Public Preferences and Willingness to Pay for a COVID-19 Vaccine in Iran: A Discrete Choice Experiment.

Darrudi, Alireza / Daroudi, Rajabali / Yunesian, Masud / Akbari Sari, Ali

PharmacoEconomics - open

2022 Volume 6, Issue 5, Page(s) 669–679

Abstract: Background and objective: The coronavirus disease 2019 (COVID-19) pandemic is a major international threat and vaccination is the most robust strategy to terminate this crisis. It is helpful for policymakers to be aware of community preferences about ... ...

Abstract	Background and objective: The coronavirus disease 2019 (COVID-19) pandemic is a major international threat and vaccination is the most robust strategy to terminate this crisis. It is helpful for policymakers to be aware of community preferences about vaccines. The present study aims to investigate the public's preferences and willingness to pay for the COVID-19 vaccine in Iran. Methods: This research is a cross-sectional study performed using a discrete choice experiment for a sample of the public population of several provinces of Iran in 2021. The samples were divided into two groups: one group expressed their preferences regarding the vaccine's attributes, and another group expressed their preferences regarding prioritizing individuals to get the vaccine. The discrete choice experiment design included five attributes including effectiveness, risk of severe complications, price, location of vaccine production, and duration of protection related to preferences for vaccine selection and six attributes including age, underlying diseases, employment in the healthcare sector, the rate of virus spread, the necessary job, and cost to the community related to preferences for prioritizing individuals to get the vaccine. A total of 715 individuals completed the questionnaire. The conditional logit regression model was used to analyze the discrete choice experiment data. Willingness to pay for each attribute was also calculated. Results: The willingness to pay for the COVID-19 vaccine with 90% (70%) efficacy, the risk of severe complications for 1 (5) person per one million people, imported (domestic) vaccine, and 24-month (12-month) duration of protection attributes was about US$71 (US$37). The preference for vaccination for respondents was enhanced by increasing the efficacy and the duration of vaccine protection and decreasing complications and costs. The likelihood of prioritizing individuals to get a vaccination was increased for a person with an underlying disease, employment in the healthcare sector, the necessary job for the community, the high potential for virus spread in the community, and the high cost of death to the community. The age variable was not statistically significant for prioritizing individuals to get the vaccine. Conclusions: In the setting of the COVID-19 vaccination program, the public's preferences identified in this study should be considered. The obtained results provide useful information for policymakers to identify individual and social values for an appropriate vaccination strategy.
Language	English
Publishing date	2022-08-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2874287-4
ISSN	2509-4254 ; 2509-4262
ISSN (online)	2509-4254
ISSN	2509-4262
DOI	10.1007/s41669-022-00359-x
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Article: Exposure sources of polychlorinated biphenyls (PCBs) and health risk assessment: a systematic review in Iran

Ravanipour, Masoumeh / Nabipour, Iraj / Yunesian, Masud / Rastkari, Noushin / Mahvi, Amir Hossein

Environmental science and pollution research. 2022 Aug., v. 29, no. 37

2022

Abstract: This systematic review aims to identify the sources of exposure to polychlorinated biphenyls (PCBs), portioning, and human health risk assessment in Iran. The literature was searched in the international databases of Web of Science, PubMed, Scopus, ... ...

Abstract	This systematic review aims to identify the sources of exposure to polychlorinated biphenyls (PCBs), portioning, and human health risk assessment in Iran. The literature was searched in the international databases of Web of Science, PubMed, Scopus, Google Scholar, and the national databases of SID and MagIran up to November 14, 2020. Among all 153 articles, 21 eligible papers were identified. Among them, only one article was related to drinking water, the rest was related to food and soil, and no article was found on ambient air. The corrected portion of each exposure source was determined to be 90% for food, 9% for water, and 1% for air. The total hazard quotient (HQ) was determined to be within an unsafe range, and the total excess lifetime cancer risk (ELCR) was determined to be at a high risk of oral carcinogenesis. It is suggested that a comprehensive study be conducted in a specific period for all sources of exposure in all counties of Iran. Moreover, it is recommended that the policymakers set national standards for this pollutant in near future in some sources of exposure (e.g., drinking water) which have no standards in Iran.
Keywords	air ; carcinogenesis ; exposure pathways ; health effects assessments ; human health ; pollutants ; pollution ; polychlorinated biphenyls ; research ; risk ; soil ; systematic review ; Iran
Language	English
Dates of publication	2022-08
Size	p. 55437-55456.
Publishing place	Springer Berlin Heidelberg
Document type	Article
Note	Review
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-21274-y
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