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  1. Article ; Online: A time-space conversion method for material synthesis research

    Yuting Hou / Minghao Liang / Fangzhu Qing / Xuesong Li

    iScience, Vol 24, Iss 11, Pp 103340- (2021)

    2021  

    Abstract: Summary: Research on material synthesis is mostly performed through batch by batch testing with each corresponding to a set of parameters and a reaction time. Concurrent experiments that allow for multiple loadings throughout an inhomogeneous reaction ... ...

    Abstract Summary: Research on material synthesis is mostly performed through batch by batch testing with each corresponding to a set of parameters and a reaction time. Concurrent experiments that allow for multiple loadings throughout an inhomogeneous reaction zone provide a way to obtain high-throughput results. Here, a time-space conversion method is proposed. By sequentially passing a number of identical objects through a reaction zone, a significant diversity of reactions in one batch can be achieved depending on the spatial distribution and changes with time of the reaction zone. In particular, when the reaction zone is steady, the evolution of a reaction can be associated with the objects at their corresponding reaction stage. This greatly improves the efficiency and accuracy of research on material synthesis kinetics. This method may initiate a new wave of material synthesis research and accelerate the development of material science.
    Keywords Materials science ; Materials synthesis ; Nanomaterials ; Science ; Q
    Subject code 660
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Spatiotemporal evolution of island ecological quality under different urban densities

    Chao Liu / Minghui Yang / Yuting Hou / Yuning Zhao / Xiongzhi Xue

    Ecological Indicators, Vol 124, Iss , Pp 107438- (2021)

    A comparative analysis of Xiamen and Kinmen Islands, southeast China

    2021  

    Abstract: Island ecosystems are increasingly threatened by pressures from both climate change and intensifying human activity, especially in developing countries. Evaluation of ecological quality is essential to implementation of interventions for adapting to ... ...

    Abstract Island ecosystems are increasingly threatened by pressures from both climate change and intensifying human activity, especially in developing countries. Evaluation of ecological quality is essential to implementation of interventions for adapting to climate change and alleviating human–nature land-use conflicts in the Anthropocene era. However, the temporal and spatial characteristics of island ecological quality, including variation arising from anthropogenic perturbations, climate change effects, and spatiotemporal heterogeneity, are rarely given serious attention. This study compares Xiamen Island and Kinmen Island, two neighboring islands with pronounced differences in urban density, adopting a Remote Sensing Ecological Index (RSEI) to describe the spatiotemporal differences in island ecological quality. The results show that the RSEI was positively correlated with greenness and humidity and negatively correlated with heat and dryness. Despite the fact that Xiamen Island has experienced extensive urban expansion and rapid population growth, its ecological quality has remained stable and even improved slightly, which mainly due to scientific urban planning. Despite the ecological advantages of its less urban setting, Kinmen Island has suffered reduced ecological quality due to deterioration of natural conditions, climate warming, and increasing human activity. These research findings provide empirical evidence for the need for scientific and systematic urban planning in high-density urban areas and serves as an important reference for planners and decision-makers for effective improvement in the ecological quality of Kinmen Island.
    Keywords Remote sensing ecological index ; Ecological environment evaluation ; Principal component analysis ; Urban planning ; Islands ; Ecology ; QH540-549.5
    Subject code 910
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Foliar applications of various nitrogen (N) forms to winter wheat affect grain protein accumulation and quality via N metabolism and remobilization

    Xiaokang Lyu / Yang Liu / Na Li / Liban Ku / Yuting Hou / Xiaoxia Wen

    Crop Journal, Vol 10, Iss 4, Pp 1165-

    2022  Volume 1177

    Abstract: Foliar nitrogen (N) application is an effective strategy to improve protein content and quality in wheat kernels, but the specific effects of N forms remain unclear. In a two-year field study, foliar application of various N forms (NO3-, urea, NH4+) at ... ...

    Abstract Foliar nitrogen (N) application is an effective strategy to improve protein content and quality in wheat kernels, but the specific effects of N forms remain unclear. In a two-year field study, foliar application of various N forms (NO3-, urea, NH4+) at anthesis was performed to measure their effects on wheat grain protein accumulation, quality formation, and the underlying mechanisms. Foliar application of three N forms showed varying effects in improving grain gluten proteins and quality traits. Under NH4+ application, there was more post-anthesis N uptake for grain filling, with relatively strong increase in enzyme activities and gene expression associated with N metabolism in flag leaves at 8–20 days after anthesis (DAA), whereas its promotion of grain N metabolism became weaker after 20 DAA than those under NO3- and urea treatments. More N was remobilized from source organs to grain under treatment with foliar NO3- and urea. Genes controlling the synthesis of gluten protein and disulfide bonds were upregulated by NO3- and urea at 20–28 DAA, contributing to increased grain protein content and quality. Overall, foliar applications of NO3- and urea were more effective than those of NH4+ in increasing grain N filling. These findings show that manipulating the source–sink relationship by reinforcing grain N metabolism and N remobilization is critical for optimizing grain protein accumulation and quality formation.
    Keywords Nitrogen remobilization ; Source-Sink ; Gluten protein ; Grain filling ; Quality formation ; Agriculture ; S ; Agriculture (General) ; S1-972
    Subject code 669
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher KeAi Communications Co., Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Pectin Penta-Oligogalacturonide Suppresses Intestinal Bile Acids Absorption and Downregulates the FXR-FGF15 Axis in High-Cholesterol Fed Mice

    Zhu, Rugang / Yuting Hou / Yandi Sun / Tuoping Li / Jungang Fan / Gang Chen / Junxiu Wei

    Lipids. 2017 June, v. 52, no. 6

    2017  

    Abstract: Haw pectin penta-oligogalacturonide (HPPS), purified from the hydrolysates of haw pectin, has important role in decreasing hepatic cholesterol accumulation and promoting bile acids (BA) excretion in the feces of mice fed a high-cholesterol diet (HCD). ... ...

    Abstract Haw pectin penta-oligogalacturonide (HPPS), purified from the hydrolysates of haw pectin, has important role in decreasing hepatic cholesterol accumulation and promoting bile acids (BA) excretion in the feces of mice fed a high-cholesterol diet (HCD). However, the mechanism is not clear. This study aims to investigate the effects of HPPS on BA reabsorption in ileum and biosynthesis in liver of mice. Results showed that HPPS increased fecal BA output by approximately 110%, but decreased ileal BA and the total BA pool size by approximately 47 and 36%, respectively, compared to HCD. Studies of molecular mechanism revealed that HPPS significantly decreased the mRNA and protein levels of farnesoid X receptor (FXR) in the small intestine of mice and inactivated the fibroblast growth factor 15 (FXR-FGF15) axis, which increased the mRNA and protein levels of CYP7A1 by approximately 204 and 104%, respectively, compared to HCD. Interestingly, the mRNA and protein levels of apical sodium-dependent bile acid transporter (ASBT) in the small intestine were approximately 128 and 73% higher in HPPS-fed mice than those in HCD-fed mice, respectively. However, no significant difference was detected for ASBT expression between HCD group and BA sequestrant cholestyramine group. These findings indicate that HPPS can suppress intestinal BA reabsorption and promoting hepatic BA biosynthesis. We speculated that HPPS could be ASBT competitive inhibitor rather than BA sequestrant in inhibiting BA reabsorption in ileum and improving cholesterol metabolism.
    Keywords bile acids ; biosynthesis ; cholesterol ; cholesterol metabolism ; cholestyramine ; excretion ; feces ; fibroblast growth factors ; high fat diet ; hydrolysates ; ileum ; liver ; messenger RNA ; mice ; pectins
    Language English
    Dates of publication 2017-06
    Size p. 489-498.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    ZDB-ID 241539-2
    ISSN 1558-9307 ; 0024-4201
    ISSN (online) 1558-9307
    ISSN 0024-4201
    DOI 10.1007/s11745-017-4258-x
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Rapid pathogen identification using a novel microarray-based assay with purulent meningitis in cerebrospinal fluid

    Yuting Hou / Xu Zhang / Xiaolin Hou / Ruofen Wu / Yanbai Wang / Xuexian He / Libin Wang / Zhenhai Wang

    Scientific Reports, Vol 8, Iss 1, Pp 1-

    2018  Volume 10

    Abstract: Abstract In order to improve the diagnosis of pathogenic bacteria in cerebrospinal fluid (CSF) with purulent meningitis, we developed a DNA microarray technique for simultaneous detection and identification of seven target bacterium. DNA were extracted ... ...

    Abstract Abstract In order to improve the diagnosis of pathogenic bacteria in cerebrospinal fluid (CSF) with purulent meningitis, we developed a DNA microarray technique for simultaneous detection and identification of seven target bacterium. DNA were extracted from 24 CSF samples with purulent meningitis (or suspected purulent meningitis). The specific genes of each pathogen were chosen as the amplification target, performed the polymerase chain reaction (PCR), labeled with a fluorescence dye, and hybridized to the oligonucleotide probes on the microarray. There is no significant cross-hybridization fluorescent signal occurred in untargeted bacteria. There were 87.5% (21/24) positive results in DNA microarray compared with the 58.3% (14/24) of the CSF culture test. Of which 58.3% (14/24) of the patients with culture-confirmed purulent meningitis, 37.5% (9/24) patients who were not confirmed by culture test but were demonstrated by the clinical diagnosis and DNA microarray. Multiple bacterial infections were detected in 5 cases by the microarray. In addition, the number of gene copies was carried out to determine the sensitivity of this technique, which was shown to be 3.5 × 101 copies/μL. The results revealed that the microarray technique which target pathogens of the CSF specimen is better specificity, accuracy, and sensitivity than traditional culture method. The microarray method is an effective tool for rapidly detecting more target pathogens and identifying the subtypes of strains which can eliminate the impact of the different individuals with purulent meningitis for prompt diagnosis and treatment.
    Keywords Medicine ; R ; Science ; Q
    Subject code 500
    Language English
    Publishing date 2018-10-01T00:00:00Z
    Publisher Nature Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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