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Article ; Online: Research Progress of Radiomics in the Diagnosis of Pulmonary Nodules

Yuting LIU / Aishi LIU

CT Lilun yu yingyong yanjiu, Vol 32, Iss 4, Pp 573-

2023 Volume 578

Abstract: In recent years, with the continuous improvement of medical level, people pay more attention to their own health, pulmonary nodules and other space-occupying lesions can be detected earlier, but on a global scale, the number of deaths caused by malignant ...

Abstract	In recent years, with the continuous improvement of medical level, people pay more attention to their own health, pulmonary nodules and other space-occupying lesions can be detected earlier, but on a global scale, the number of deaths caused by malignant lung lesions Still rising and remaining high. Radiomics is an emerging field that aims to derive automated quantitative imaging features from medical images to noninvasively predict nodular and tumor behavior. Compared with traditional visual image features, radiomics can extract more nodular features with better reproducibility. The scientific and systematic use of radiomics can not only prevent excessive medical behaviors and reduce the economic burden of patients, but also enable patients with lung lesions to receive early treatment for the best prognosis.
Keywords	radiomics ; pulmonary nodules ; malignant pulmonary diease ; Geophysics. Cosmic physics ; QC801-809 ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2023-07-01T00:00:00Z
Publisher	Editorial Office of Computerized Tomography Theory and Application
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Recent Advances of N -2,2,2-Trifluoroethylisatin Ketimines in Organic Synthesis

Yuting Liu / Lijie Wang / Donglai Ma / Yongxing Song

Molecules, Vol 28, Iss 2990, p

2023 Volume 2990

Abstract: The special properties of fluorine atoms and fluorine-containing groups have led to an increasing number of applications for fluorine-containing organic compounds, which are also extremely widely used in the field of new drug development. Unfortunately, ... ...

Abstract	The special properties of fluorine atoms and fluorine-containing groups have led to an increasing number of applications for fluorine-containing organic compounds, which are also extremely widely used in the field of new drug development. Unfortunately, naturally fluorinated organics are rare in nature, so the selective introduction of fluorine atoms or fluorine-containing groups into organic molecules is very important for pharmaceutical/synthetic chemists. N -2,2,2-trifluoroethylisatin ketimines have received the attention of many chemists since they were first developed as fluorine-containing synthons in 2015. This paper reviews the organic synthesis reactions in which trifluoroethyl isatin ketimine has been involved in recent years, focusing on the types of reactions and the stereoselectivity of products, and also provides a prospect of its application in this field.
Keywords	N -2,2,2-trifluoroethylisatin ketimine ; trifluoromethyl ; cycloaddition ; organic synthesis ; cascade reaction ; Organic chemistry ; QD241-441
Subject code	540
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Beyond Homeownership? Examining the Mediating Role of Housing Tenure on Young People’s Subjective Well-Being

Haitong Mo / Yung Yau / Yuting Liu

Land, Vol 12, Iss 678, p

2023 Volume 678

Abstract: Young people around the world are facing similar housing challenges, trapped between a costly and unaffordable homeownership sector and an unstable (private) rental sector. China has opted to promote renting as an alternative to homeownership to ... ...

Abstract	Young people around the world are facing similar housing challenges, trapped between a costly and unaffordable homeownership sector and an unstable (private) rental sector. China has opted to promote renting as an alternative to homeownership to alleviate the housing difficulties of young people in big cities. However, the influences of promoting rental housing on the subjective well-being of different groups have not been well understood. Therefore, this study examines the mediating role of housing tenure in the relationship between individual attributes and subjective well-being. The study is based on 1,149 questionnaires conducted on the housing situations of residents in Guangzhou, and 618 samples were extracted for analysis based on the purpose of this study. It is found that individual, marital status, (local/nonlocal) hukou status, and income level have significant indirect effects on subjective well-being, with housing tenure as the mediator. This study contributes to a deeper understanding of the influencing mechanisms of subjective well-being associated with housing tenure and human heterogeneity and specifies the key points for future research and policymaking.
Keywords	housing tenure ; subjective well-being ; young people ; mediating effect ; urban China ; Agriculture ; S
Subject code	720
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Full-round impossible differential attack on shadow block cipher

Yuting Liu / Yongqiang Li / Huiqin Chen / Mingsheng Wang

Cybersecurity, Vol 6, Iss 1, Pp 1-

2023 Volume 15

Abstract: Abstract Lightweight block ciphers are the essential encryption algorithm for devices with limited resources. Its goal is to ensure the security of data transmission through resource-constrained devices. Impossible differential cryptanalysis is one of ... ...

Abstract	Abstract Lightweight block ciphers are the essential encryption algorithm for devices with limited resources. Its goal is to ensure the security of data transmission through resource-constrained devices. Impossible differential cryptanalysis is one of the most effective cryptanalysis on block ciphers, and assessing the ability of resisting this attack is a basic design criterion. Shadow is a lightweight block cipher proposed by Guo et al. (IEEE Internet Things J 8(16):13014–13023, 2021). It utilizes a combination of ARX operations and generalized Feistel structure to overcome the weakness of the traditional Feistel structure that only diffuses half in one round. In this paper, we focus on the differential property of Shadow and its security against impossible differential cryptanalysis. First, we use the SAT method to automatically search for a full-round impossible differential distinguisher of Shadow-32. Then, based on the experimental results, we prove that Shadow has a differential property with probability 1 based on the propagation of the state. Further, we can obtain an impossible differential distinguisher for an arbitrary number of rounds of Shadow. Finally, we perform a full key recovery attack on the full-round Shadow-32 and Shadow-64. Both experimentally and theoretically, our results indicate that Shadow is critically flawed, and regardless of the security strength of the internal components and the number of rounds applied, the overall cipher remains vulnerable to impossible differential cryptanalysis.
Keywords	Lightweight block cipher ; Shadow ; Impossible differential cryptanalysis ; SAT ; Computer engineering. Computer hardware ; TK7885-7895 ; Electronic computers. Computer science ; QA75.5-76.95
Subject code	005
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Primary Amine Functionalized Carbon Dots for Dead and Alive Bacterial Imaging

Yuting Liu / Di Zhong / Lei Yu / Yanfeng Shi / Yuanhong Xu

Nanomaterials, Vol 13, Iss 437, p

2023 Volume 437

Abstract: Small molecular dyes are commonly used for bacterial imaging, but they still meet a bottleneck of biological toxicity and fluorescence photobleaching. Carbon dots have shown high potential for bio-imaging due to their low cost and negligible toxicity and ...

Abstract	Small molecular dyes are commonly used for bacterial imaging, but they still meet a bottleneck of biological toxicity and fluorescence photobleaching. Carbon dots have shown high potential for bio-imaging due to their low cost and negligible toxicity and anti-photobleaching. However, there is still large space to enhance the quantum yield of the carbon quantum dots and to clarify their mechanisms of bacterial imaging. Using carbon dots for dyeing alive bacteria is difficult because of the thick density and complicated structure of bacterial cell walls. In this work, both dead or alive bacterial cell imaging can be achieved using the primary amine functionalized carbon dots based on their small size, excellent quantum yield and primary amine functional groups. Four types of carbon quantum dots were prepared and estimated for the bacterial imaging. It was found that the spermine as one of precursors can obviously enhance the quantum yield of carbon dots, which showed a high quantum yield of 66.46% and high fluorescence bleaching-resistance (70% can be maintained upon 3-h-irradiation). Furthermore, a mild modifying method was employed to bound ethylenediamine on the surface of the spermine–carbon dots, which is favorable for staining not only the dead bacterial cells but also the alive ones. Investigations of physical structure and chemical groups indicated the existence of primary amine groups on the surface of spermine–carbon quantum dots (which own a much higher quantum yield) which can stain alive bacterial cells visibly. The imaging mechanism was studied in detail, which provides a preliminary reference for exploring efficient and environment-friendly carbon dots for bacterial imaging.
Keywords	carbon dots ; bacteria ; imaging ; Chemistry ; QD1-999
Subject code	530
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Three-Dimensional-Bioprinted Bioactive Glass/Cellulose Composite Scaffolds with Porous Structure towards Bone Tissue Engineering

Lei Li / Pengfei Lu / Yuting Liu / Junhe Yang / Shengjuan Li

Polymers, Vol 15, Iss 2226, p

2023 Volume 2226

Abstract: In this study, three-dimensional (3D) bioactive glass/lignocellulose (BG/cellulose) composite scaffolds were successfully fabricated by the 3D-bioprinting technique with N -methylmorpholine- N -oxide (NMMO) as the ink solvent. The physical structure, ... ...

Abstract	In this study, three-dimensional (3D) bioactive glass/lignocellulose (BG/cellulose) composite scaffolds were successfully fabricated by the 3D-bioprinting technique with N -methylmorpholine- N -oxide (NMMO) as the ink solvent. The physical structure, morphology, mechanical properties, hydroxyapatite growth and cell response to the prepared BG/cellulose scaffolds were investigated. Scanning electron microscopy (SEM) images showed that the BG/cellulose scaffolds had uniform macropores of less than 400 μm with very rough surfaces. Such BG/cellulose scaffolds have excellent mechanical performance to resist compressive force in comparison with pure cellulose scaffolds and satisfy the strength requirement of human trabecular bone (2–12 MPa). Furthermore, BG significantly increased the excellent hydroxyapatite-forming capability of the cellulose scaffolds as indicated by the mineralization of the scaffolds in simulated body fluid (SBF). The BG/cellulose scaffolds showed low cytotoxicity to human bone marrow mesenchymal stem cells (hBMSCs) in the CCK8 assay. The cell viability reached maximum (percent of the control group) when the weight ratio of cellulose to BG was 2 in the scaffold. Therefore, the 3D-printed BG/cellulose scaffolds show a potential application in the field of bone tissue engineering.
Keywords	3D printing ; biomaterials ; lignocellulose ; bioactive glass ; biocompatibility ; bone tissue engineering scaffold ; Organic chemistry ; QD241-441
Subject code	541
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Exosome-Transmitted miR-128 Targets CCL18 to Inhibit the Proliferation and Metastasis of Urothelial Carcinoma

Donghao Shang / Yuting Liu / Zhenghao Chen

Frontiers in Molecular Biosciences, Vol

2022 Volume 8

Abstract: Objective: To investigate the regulatory function of exosome-transmitted miR-128 and chemokine (C-C motif) ligand 18 (CCL18) on urothelial carcinomas (UCs).Methods: Tumor tissues, paracancerous tissues, and serum were collected from 20 patients with UCs ( ...

Abstract	Objective: To investigate the regulatory function of exosome-transmitted miR-128 and chemokine (C-C motif) ligand 18 (CCL18) on urothelial carcinomas (UCs).Methods: Tumor tissues, paracancerous tissues, and serum were collected from 20 patients with UCs (diagnosed at Beijing Friendship Hospital, Capital Medical University). CCL18 was detected by immunohistochemistry and ELISA. PCR was used to measure the expression levels of CCL18 and mir-183, miR-128, mir-33a in UCs. We acquired exosomes from mesenchymal stem cells and synthesized exosomes overexpressing miR-128 (HMSC-128-EV). The effects of miR-128 on the migration and invasion abilities, apoptosis and epithelial-mesenchymal transition of BUC T24 cells were investigated by co-culturing HMSC-128-EV. The therapeutic potential of miR-128 on disease models was explored by injecting HMSC-128-EV into nude mice.Results: The expression of CCL18 in UCs was significantly higher than that in normal tissues (p < 0.05), and the serum level of CCL18 in patients with UC was significantly increased compared with those in healthy controls (p < 0.05). CCL18 overexpression or downregulation enhanced or suppressed the proliferation, migration and invasion of BUC T24 cells, resectively (p < 0.05). The exosome-transmitted miR-128 can inhibit cell proliferation (p < 0.05), invasion (p < 0.05), and migration (p < 0.05) in UCs, and these effects can be reversed by CCL18. In terms of apoptosis, miR-128 was able to promote the occurrence of BUC T24 apoptosis (p < 0.05), which can also be reversed by CCL18. In addition, miR-128 can inhibit the proliferation (p < 0.05) and metastasis (p < 0.05) of UCs in nude mice.Conclusion: The miR-128 inhibits the proliferation, invasion, migration of UCs, and promotes its apoptosis by regulating CCL18 secretion.
Keywords	exosome ; urothelial carcinoma ; miR-128 ; chemokine (C-C motif) ligand 18 ; proliferation ; metastasis ; Biology (General) ; QH301-705.5
Subject code	500
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Detail Injection-Based Convolutional Auto-Encoder for Pansharpening

Ming Li / Jingzhi Li / Yuting Liu / Fan Liu

Journal of Remote Sensing, Vol

2022 Volume 2022

Abstract: The purpose of pansharpening is to generate high-resolution multispectral (MS) images using both low-resolution MS images and high-resolution panchromatic images. Traditional remote sensing image fusion algorithms can be simplified to a unified detail ... ...

Abstract	The purpose of pansharpening is to generate high-resolution multispectral (MS) images using both low-resolution MS images and high-resolution panchromatic images. Traditional remote sensing image fusion algorithms can be simplified to a unified detail injection (Di) context that treats the injected MS details as panchromatic-detail and integration with injection gain. The injected details are developed from traditional fusion strategies with clear physical interpretation and facilitate fast convergence of deep learning models for high-quality image fusion. The excellent ability of convolutional autoencoder (CAE) networks to retain image information enables its application to remote sensing image fusion. In this paper, a fusion method Di-based CAE (DiCAE) based on Di and CAE is proposed. DiCAE method is based on Di as the theoretical foundation and CAE network as the core of the algorithm. In addition, our method is evaluated through experiments on different satellite datasets, and the fusion results obtained by DiCAE have better objective evaluation metrics and better visual results compared to other state-of-the-art methods.
Keywords	Environmental sciences ; GE1-350 ; Physical geography ; GB3-5030
Subject code	006
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	American Association for the Advancement of Science (AAAS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Reconstructed Cu/Cu2O(I) catalyst for selective electroreduction of CO2 to C2+ products

Yuting Liu / Hua Liu / Cheng Wang / Yali Wang / Jiaxing Lu / Huan Wang

Electrochemistry Communications, Vol 150, Iss , Pp 107474- (2023)

2023

Abstract: It is particularly desirable for the development of carbon utilization technologies to synthesize multicarbon products (C2+) from the electrochemical CO2 reduction reaction (CO2RR). In this work, Cu/Cu2O(X) catalysts (where X = I, Br, Cl) for selective ... ...

Abstract	It is particularly desirable for the development of carbon utilization technologies to synthesize multicarbon products (C2+) from the electrochemical CO2 reduction reaction (CO2RR). In this work, Cu/Cu2O(X) catalysts (where X = I, Br, Cl) for selective electroreduction of CO2 to C2+ were reconstructed via cyclic voltammetry on carbon paper. The Faradaic efficiency (FE) for C2+ (C2H4, C2H5OH, C3H8OH) production over Cu/Cu2O(Cl), Cu/Cu2O(Br) and Cu/Cu2O(I) reached 31%, 34% and 58%, respectively, at a potential of −0.76 V vs. the reversible hydrogen electrode (RHE). The Cu+ and Cu0 species obtained from the reconstruction of Cu/CuX are primarily responsible for the high C2+ producing activity.
Keywords	CO2RR ; Cu/Cu2O(X) ; C2+ products ; Reconstruction ; Industrial electrochemistry ; TP250-261 ; Chemistry ; QD1-999
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Multi-factors influence of anchorage force on surrounding rock under coupling effect of creep rock mass and bolt/cable

Yuting Liu / Pengqiang Zheng / Pu Wang

Geomatics, Natural Hazards & Risk, Vol 12, Iss 1, Pp 328-

2021 Volume 346

Abstract: Assuming that relative sliding does not occur to the coordinated deformation of bolt/cable and surrounding rock, a constitutive model of coupling effect between bolt/cable and creep surrounding rock is established to study the variation law of anchorage ... ...

Abstract	Assuming that relative sliding does not occur to the coordinated deformation of bolt/cable and surrounding rock, a constitutive model of coupling effect between bolt/cable and creep surrounding rock is established to study the variation law of anchorage force on surrounding rock with time increasing, the parameters of physical-mechanics of bolt/cable and the mechanical parameters of surrounding rocks analyzed, and the sensitivity of the above parameters to anchorage force compared using sensitivity analysis method. Results show that the validity and effectiveness of the proposed constitutive model is verified by numerical simulation. And the main factors affecting the anchorage force for creep rock are diameter (D), elastic modulus (Ec), and initial pre-stress force (F) of bolt/cable, viscoelastic modulus (ER), viscoelastic coefficient (ηR) and initial in situ stress (σ0) of surrounding rocks, respectively. For bolt or cable, increasing the parameter values of D, Ec and F can strengthen the anchorage force; while for surrounding rocks, large value of σ0 and small value of ηR are beneficial to the exertion of anchorage force. The sensitivities of these factors from high to low are D, ER, σ0, Ec, F, ηR, respectively. The result can provide some guidance for the formulation of on-site support scheme and parameters selection.
Keywords	multi-factors ; anchorage force ; coupling effect ; creep rock mass ; bolt/cable ; Environmental technology. Sanitary engineering ; TD1-1066 ; Environmental sciences ; GE1-350 ; Risk in industry. Risk management ; HD61
Subject code	621
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Taylor & Francis Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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