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  1. Book ; Online ; E-Book: Computational Intelligence in Protein-Ligand Interaction Analysis

    Wang, Bing / Chen, Peng / Zhang, Jun

    2024  

    Subject code 572.6
    Language English
    Size 1 online resource (280 pages)
    Edition 1st ed.
    Publisher Elsevier Science & Technology
    Publishing place San Diego
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 9780128244357 ; 0128244356
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Chapter Design and reconstruction of the new interest youth community in china in the post-epidemic era

    Dong, Haoyu / Zhang, Jun

    2023  

    Keywords Interior design, decor & style guides ; design
    Language English
    Size 1 electronic resource (1 pages)
    Publisher Academia Press
    Publishing place Ghent
    Document type Book ; Online
    Note English
    HBZ-ID HT030647535
    ISBN 9789401496476 ; 9401496471
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online ; E-Book: Advances in PET

    Zhang, Jun / Knopp, Michael V.

    The Latest in Instrumentation, Technology, and Clinical Practice

    2020  

    Abstract: This book is a guide to new and emerging PET technology, instrumentation, and its place in clinical practice. PET technology is currently moving from the conventional photomultiplier tube (PMT) detector based PET to the new generation, solid state light ... ...

    Author's details edited by Jun Zhang, Michael V. Knopp
    Abstract This book is a guide to new and emerging PET technology, instrumentation, and its place in clinical practice. PET technology is currently moving from the conventional photomultiplier tube (PMT) detector based PET to the new generation, solid state light sensor detector. This is a technological leap and holds significant implications for the use of PET imaging. This book introduces and describes the emerging and new generation of PET instrumentations and technologies across manufactures, focusing on solid-state PET detector designs, system characteristics, and clinical practices as well as future advanced Time-of-Flight (TOF) PET technologies. Organized into three sections, the basics of PET imaging; solid state digital PET instrumentation, technology, and clinical practice; and a look to the future of PET imaging, chapters present a full picture of PET imaging, where we are and where we will be. Nuclear medicine physicians, physicists, and technologists can use this book to better understand future PET systems, novel PET technologies, and potential game changes of clinical PET practice.
    Keywords Nuclear medicine ; Radiology ; Nuclear Medicine ; Diagnostic Radiology
    Subject code 616.07575
    Language English
    Size 1 online resource (110 pages)
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-43040-5 ; 3-030-43039-1 ; 978-3-030-43040-5 ; 978-3-030-43039-9
    DOI 10.1007/978-3-030-43040-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Assessing the effect of the improvement of environmental damage compensation legal system and green finance project on the re-establishment of the ecological environment.

    Zhang, Jun

    Environmental science and pollution research international

    2023  Volume 30, Issue 25, Page(s) 67662–67675

    Abstract: What are the relationships among environmental regulations, green finance, and environmental damages in countries? Existing literature supports the impact of green finance or green innovation on environmental quality, but rare studies query the ... ...

    Abstract What are the relationships among environmental regulations, green finance, and environmental damages in countries? Existing literature supports the impact of green finance or green innovation on environmental quality, but rare studies query the cointegration among other core variables. We thus utilize the yearly data of 25 Chinese provinces from 2003 to 2021 to empirically examine the relationships among access to clean energy and technology, environmental regulation, renewable green investment, subsidy on green energy, and green finance index in environmental damage compensation via an augmented mean group (AMG) and other estimators. However, the current empirical research also investigates the individual linkage of green finance components with explained variables. Overall, this study confirms the existence of cointegration relationships among these variables. Moreover, the results of AMG suggest that access to clean fuels and technology, environmental regulations, and green finance can inversely affect the explained variable in the long term. Furthermore, environmental regulations and renewable green investment positively affect environmental damages, while a separate proxy of green finance also negatively affects explained variables in the selected provinces with better environmental performance. Our empirical findings offer important policy implications for overall emerging economies to promote subsidies, environmental regulations, and green finance to improve environmental damages compensation.
    MeSH term(s) China ; Economic Development ; Empirical Research ; Environment ; Investments ; Policy ; Renewable Energy
    Language English
    Publishing date 2023-04-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-26877-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The effect of carbon tax incidence on household energy demand and welfare in the U.S.

    Zhang, Jun

    Environmental science and pollution research international

    2022  Volume 30, Issue 5, Page(s) 13210–13223

    Abstract: This study develops a model based on a general equilibrium framework to assess the excess burden of carbon taxes imposed on energy commodities (electricity and natural gas) among residential sector. The model takes into account labor market distortions ... ...

    Abstract This study develops a model based on a general equilibrium framework to assess the excess burden of carbon taxes imposed on energy commodities (electricity and natural gas) among residential sector. The model takes into account labor market distortions from the tax and cross-price effects among energy commodities. Using data from the U.S. Residential Energy Consumption Survey, the own-price and cross-price elasticities of energy commodities are estimated. A substitution effect is found between electricity and natural gas, and omitting this effect would overestimate the excess burden of the carbon tax. The results show that the carbon tax behaves differently in affecting the excess burden for low-, middle-, and high-income households. The excess burden is lower for high-income households than for low-income households at lower pre-determined labor tax rates, but the effect is reversed at higher pre-determined labor tax rates. In addition, the empirical results show that the excess burden is different across the nine U.S. regions, while minor gas price changes have no significant effect on the excess burden.
    MeSH term(s) Incidence ; Natural Gas ; Taxes ; Income ; Poverty ; Commerce
    Chemical Substances Natural Gas
    Language English
    Publishing date 2022-09-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-022-22882-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Exploring Orthographic Representation in Chinese Handwriting: A Mega-Study Based on a Pedagogical Corpus of CFL Learners.

    Zhang, Jun

    Frontiers in psychology

    2022  Volume 13, Page(s) 782345

    Abstract: Writing and reading are closely related and are thus likely to have a common orthographic representation. A fundamental question in the literature on the production of written Chinese characters concerns the structure of orthographic representations. We ... ...

    Abstract Writing and reading are closely related and are thus likely to have a common orthographic representation. A fundamental question in the literature on the production of written Chinese characters concerns the structure of orthographic representations. We report on a Chinese character handwriting pedagogical corpus involving a class of 22 persons, 232 composite character types, 1,913 tokens, and 13,057 stroke records, together with the inter-stroke interval (ISI), which reflects the parallel processing of multilevel orthographic representation during the writing execution, and 50 orthographic variables from the whole character, logographeme, and stroke. The results of regression analyses show that orthographic representation has a hierarchy and that different representational levels are active simultaneously. In the multilevel structure of orthographic representation, the representation of the logographeme is absolutely dominant. Writing and reading have both commonalities and individual differences in their orthographic representations. The online processing of the logographeme unit probably occurs at the ISI before the initial stroke of the current logographeme, which may also cascade to the first subsequent logographeme. In addition, we propose a new effective character structure unit for describing orthographic complexity.
    Language English
    Publishing date 2022-03-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.782345
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Atom typing using graph representation learning: How do models learn chemistry?

    Zhang, Jun

    The Journal of chemical physics

    2022  Volume 156, Issue 20, Page(s) 204108

    Abstract: Atom typing is the first step for simulating molecules using a force field. Automatic atom typing for an arbitrary molecule is often realized by rule-based algorithms, which have to manually encode rules for all types defined in this force field. These ... ...

    Abstract Atom typing is the first step for simulating molecules using a force field. Automatic atom typing for an arbitrary molecule is often realized by rule-based algorithms, which have to manually encode rules for all types defined in this force field. These are time-consuming and force field-specific. In this study, a method that is independent of a specific force field based on graph representation learning is established for automatic atom typing. The topology adaptive graph convolution network (TAGCN) is found to be an optimal model. The model does not need manual enumeration of rules but can learn the rules just through training using typed molecules prepared during the development of a force field. The test on the CHARMM general force field gives a typing correctness of 91%. A systematic error of typing by TAGCN is its inability of distinguishing types in rings or acyclic chains. It originates from the fundamental structure of graph neural networks and can be fixed in a trivial way. More importantly, analysis of the rationalization processes of these models using layer-wise relation propagation reveals how TAGCN encodes rules learned during training. Our model is found to be able to type using the local chemical environments, in a way highly in accordance with chemists' intuition.
    MeSH term(s) Algorithms ; Neural Networks, Computer
    Language English
    Publishing date 2022-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0095008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Biomarkers of endothelial activation and dysfunction in cardiovascular diseases.

    Zhang, Jun

    Reviews in cardiovascular medicine

    2022  Volume 23, Issue 2, Page(s) 73

    Abstract: Endothelial activation and dysfunction is an important contributor to atherosclerosis, cardiovascular diseases and cardiorenal syndrome. Endothelial dysfunction is also linked with metabolic syndrome and type II diabetes. The search for specific and ... ...

    Abstract Endothelial activation and dysfunction is an important contributor to atherosclerosis, cardiovascular diseases and cardiorenal syndrome. Endothelial dysfunction is also linked with metabolic syndrome and type II diabetes. The search for specific and sensitive biomarkers of endothelial activation and dysfunction may have important clinical implications. This review pinpoints the differences in biomarkers between endothelial activation and endothelial dysfunction in cardiovascular diseases, and then briefly describes the most relevant biomarkers of endothelial activation. Biomarkers of endothelial activation include endothelial adhesion molecules, cytokines, C-reactive protein, CD62E+/E-selectin activated endothelial microparticles, oxidation of low density lipoproteins, asymmetric dimethylarginine and endocan. This review also presents an update on the novel biomarkers of endothelial dysfunction, such as matrix metalloproteinases (e.g., MMP-7, MMP-9), ANGPTL2, endogdlin, annexin V+ endothelial apoptotic microparticles, and serum homocysteine. Finally, this review emphasizes the limitations of biomarkers of endothelial activation and dysfunction in clinical setting.
    MeSH term(s) Angiopoietin-Like Protein 2/blood ; Angiopoietin-Like Protein 2/metabolism ; Atherosclerosis/pathology ; Atherosclerosis/physiopathology ; Biomarkers/blood ; Biomarkers/metabolism ; Cardiovascular Diseases/pathology ; Cardiovascular Diseases/physiopathology ; Cell-Derived Microparticles/metabolism ; Diabetes Mellitus, Type 2/pathology ; Diabetes Mellitus, Type 2/physiopathology ; Endothelium, Vascular/pathology ; Endothelium, Vascular/physiopathology ; Humans
    Chemical Substances ANGPTL2 protein, human ; Angiopoietin-Like Protein 2 ; Biomarkers
    Language English
    Publishing date 2022-03-01
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2108910-3
    ISSN 1530-6550
    ISSN 1530-6550
    DOI 10.31083/j.rcm2302073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Mendelian Randomization Study Implies Causal Linkage Between Telomere Length and Juvenile Idiopathic Arthritis in a European Population.

    Zhang, Jun

    Journal of inflammation research

    2022  Volume 15, Page(s) 977–986

    Abstract: Background: Telomere maintenance is increasingly being considered as fundamental to the progression of immune-mediated inflammatory diseases. However, the causality underlying the purported relationship has not been fully elucidated. In the present work, ...

    Abstract Background: Telomere maintenance is increasingly being considered as fundamental to the progression of immune-mediated inflammatory diseases. However, the causality underlying the purported relationship has not been fully elucidated. In the present work, we applied Mendelian randomization (MR) analysis to obtain estimates of the causal effect of telomere length (TL) on the risk of juvenile idiopathic arthritis (JIA) and JIA-associated iridocyclitis.
    Methods: Two-sample MR analysis was conducted using summary-level data from the largest genome-wide association studies concerning TL (78,592 individuals), JIA (6056 cases and 25,086 controls), and JIA-associated iridocyclitis (1430 cases and 9,2767 controls). All the participants were of European ancestry. The inverse variance weighted (IVW) method was applied to estimate the causal effects. Sensitivity analyses incorporating multiple complementary MR approaches were implemented to test the robustness of the association and examine potential bias from pleiotropy.
    Results: In our MR analysis, genetically predicted shorter TL was associated with an increased risk of JIA (IVW: odds ratio=1.68, 95% CI: 1.13-2.48,
    Conclusion: This work provides evidence of a negative association between TL and JIA risk, but not for the association between TL and the risk of JIA-associated iridocyclitis, in a European population. Future studies with larger sample sizes are warranted to elucidate the underlying role of TL in these diseases.
    Language English
    Publishing date 2022-02-15
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494878-0
    ISSN 1178-7031
    ISSN 1178-7031
    DOI 10.2147/JIR.S354619
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: SCVerify

    ZHANG Jun

    Jisuanji kexue yu tansuo, Vol 15, Iss 6, Pp 1074-

    Verification of Software Implementation Against Power Side-Channel Attacks

    2021  Volume 1083

    Abstract: Power side-channel attacks, have become a serious threat to embedded computing devices in cyber-physical systems because of the ability of deducing secret data using statistical analysis. A common strategy for designing countermeasures against power- ... ...

    Abstract Power side-channel attacks, have become a serious threat to embedded computing devices in cyber-physical systems because of the ability of deducing secret data using statistical analysis. A common strategy for designing countermeasures against power-analysis-based side-channel attacks uses random masking techniques to remove the statistical dependency between secret data and side-channel information. Although existing techniques can verify whether a piece of cryptographic software code is perfectly masked, they are limited in accuracy and scalability. In order to eliminate such limitations, a refinement-based method for verifying masking countermeasures is proposed. This method is more accurate than prior type-inference based approaches and more scalable than prior model-counting based approaches using satisfiability (SAT) or satisfiability modulo theories (SMT) solvers. Indeed, this method uses a set of semantic type-inference rules to reason about distribution type. These rules are kept abstract initially to allow fast deduction, and then specified when the abstract version is not able to resolve the verification problem. This method is implemented in a software tool called SCVerify and is evaluated on cryptographic benchmarks including advanced encryption standard (AES) and message authentication code Keccak (MAC-Keccak). The experimental results show that the method significantly outperforms state-of-the-art techniques in terms of accuracy and scalability.
    Keywords side channel attack ; satisfiability modulo theories (smt) ; software verification ; type inference ; formal verification ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 005
    Language Chinese
    Publishing date 2021-06-01T00:00:00Z
    Publisher Journal of Computer Engineering and Applications Beijing Co., Ltd., Science Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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