Article ; Online: Role of Ultrasound Elastography in Patient Selection for Prostatic Artery Embolization.
Journal of vascular and interventional radiology : JVIR
2021 Volume 32, Issue 10, Page(s) 1410–1416
Abstract: Purpose: To determine the effects of prostatic artery embolization (PAE) on prostate elasticity as assessed using ultrasound elastography (US-E) and to describe baseline US-E's potential role in patient selection.: Materials and methods: This was a ... ...
| Abstract | Purpose: To determine the effects of prostatic artery embolization (PAE) on prostate elasticity as assessed using ultrasound elastography (US-E) and to describe baseline US-E's potential role in patient selection. Materials and methods: This was a prospective investigation that included 20 patients undergoing PAE to treat lower urinary tract symptoms attributed to benign prostatic hyperplasia (BPH). US-E with measurement of the prostatic elastic modulus (EM) and shear wave velocity (SWV) was performed before PAE and at 1-month follow-up. Baseline, 3-month, and 1-year follow-up evaluations included prostate-specific antigen, uroflowmetry, pelvic magnetic resonance imaging, and clinical assessment using the International Prostate Symptom Score (IPSS) and quality of life (QoL) metrics. Results: Seventeen patients entered statistical analysis. US-E showed a significant reduction in mean prostatic EM (34.4 kPa vs 46.3 kPa, -24.7%, P < .0001) and SWV (3.55 m/s vs 4.46 m/s, -20.0%, P < .0001) after PAE. There were moderate positive correlations between baseline EM and 1-year IPSS (R = 0.62, P = .007) and between baseline SWV and 1-year IPSS (R = 0.68, P = .002). Baseline SWV ≥ 5.59 m/s and baseline EM ≥ 50.14 kPa were associated with suboptimal IPSS and QoL outcomes after PAE with high degrees of sensitivity (100%) and specificity (69-100%). Conclusions: PAE led to a positive effect on the BPH dynamic component related to prostatic elasticity. There was a moderate positive correlation between baseline prostatic elastographic parameters and 12-month IPSS. Measurement of baseline elastographic characteristics may become useful for the evaluation and selection of patients for PAE. |
|---|---|
| MeSH term(s) | Arteries/diagnostic imaging ; Elasticity Imaging Techniques ; Embolization, Therapeutic/adverse effects ; Humans ; Lower Urinary Tract Symptoms/therapy ; Male ; Patient Selection ; Prospective Studies ; Prostate/diagnostic imaging ; Prostatic Hyperplasia/complications ; Prostatic Hyperplasia/diagnostic imaging ; Prostatic Hyperplasia/therapy ; Quality of Life ; Treatment Outcome |
| Language | English |
| Publishing date | 2021-07-30 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 1137756-2 |
| ISSN | 1535-7732 ; 1051-0443 |
| ISSN (online) | 1535-7732 |
| ISSN | 1051-0443 |
| DOI | 10.1016/j.jvir.2021.07.018 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Zs.A 3720: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.