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  1. Article ; Online: Transcatheter arterial embolization in abdominal blunt trauma with active mesenteric bleeding: case series and review of literature.

    Bertelli, Riccardo / Fugazzola, Paola / Zaghi, Claudia / Taioli, Andrea / Giampalma, Emanuela / Agnoletti, Vanni / Ansaloni, Luca

    Emergency radiology

    2020  Volume 28, Issue 1, Page(s) 55–63

    Abstract: Purpose: To evaluate the safety and effectiveness of transcatheter arterial embolization (TAE) in treating traumatic mesenteric injuries with active bleeding, to report the outcome in a case series, and to compare the results with the existing data.: ... ...

    Abstract Purpose: To evaluate the safety and effectiveness of transcatheter arterial embolization (TAE) in treating traumatic mesenteric injuries with active bleeding, to report the outcome in a case series, and to compare the results with the existing data.
    Methods: All consecutive patients with active mesenteric bleeding due to blunt abdominal trauma referred to a level-one Trauma Center and treated by TAE were included; the related demographic and medical data were retrospectively reported. A literature review was conducted; all reported cases were collected and analysed together with our case series. A univariate analysis of risk factors for TAE failure, bowel necrosis, complication and length of stay was performed.
    Results: Four consecutive patients were included. Technical success was 100%. One patient developed colon ischemia after the procedure and underwent surgical treatment; another presented transient mild renal failure and late respiratory failure. No 30-day mortality was reported. These results are consistent with those reported in literature. The analysis of our cases together with case collected from literature resulted in a case series of 25 patients. Univariate analysis showed colon as site of bleeding as a significant risk factor for bowel necrosis and older age as a significant risk factor for longer length of stay. TAE failure was not significantly associated neither with a higher complication rate nor with a higher length of stay.
    Conclusion: TAE is a safe and effective procedure to control mesenteric bleeding, thus should be considered, in selected cases and in appropriate setting, as an alternative to emergency surgery.
    MeSH term(s) Abdominal Injuries/diagnostic imaging ; Abdominal Injuries/therapy ; Adult ; Aged ; Aged, 80 and over ; Computed Tomography Angiography ; Contrast Media ; Embolization, Therapeutic/methods ; Female ; Hemorrhage/therapy ; Humans ; Injury Severity Score ; Iohexol/analogs & derivatives ; Male ; Mesenteric Arteries/injuries ; Middle Aged ; Retrospective Studies ; Risk Factors ; Trauma Centers ; Treatment Failure ; Wounds, Nonpenetrating/diagnostic imaging ; Wounds, Nonpenetrating/therapy
    Chemical Substances Contrast Media ; iobitridol (182ECH14UH) ; Iohexol (4419T9MX03)
    Language English
    Publishing date 2020-07-28
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 1425144-9
    ISSN 1438-1435 ; 1070-3004
    ISSN (online) 1438-1435
    ISSN 1070-3004
    DOI 10.1007/s10140-020-01831-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Intestinal permeability, systemic endotoxemia, and bacterial translocation after open or laparoscopic resection: the critical role of bowel preparation.

    Zuccaro, Massimiliano / Zaghi, Claudia / Bollino, Ruggero

    International journal of colorectal disease

    2014  Volume 29, Issue 6, Page(s) 773–774

    MeSH term(s) Bacterial Translocation ; Colonic Neoplasms/microbiology ; Colonic Neoplasms/surgery ; Endotoxemia/etiology ; Female ; Humans ; Intestines/microbiology ; Intestines/pathology ; Laparoscopy/adverse effects ; Male
    Language English
    Publishing date 2014-04-22
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 84975-3
    ISSN 1432-1262 ; 0179-1958
    ISSN (online) 1432-1262
    ISSN 0179-1958
    DOI 10.1007/s00384-014-1867-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Subcapsular Hepatic Hematoma After Endoscopic Retrograde Cholangiopancreatography: A Case Report and Review of Literature.

    Zizzo, Maurizio / Lanaia, Andrea / Barbieri, Italo / Zaghi, Claudia / Bonilauri, Stefano

    Medicine

    2015  Volume 94, Issue 26, Page(s) e1041

    Abstract: Endoscopic retrograde cholangiopancreatography (ERCP) is one of the most frequently performed procedures for the diagnosis and treatment of biliary-pancreatic diseases. ERCP-related complications total around 2.5% to 8%, with a mortality rate ranging ... ...

    Abstract Endoscopic retrograde cholangiopancreatography (ERCP) is one of the most frequently performed procedures for the diagnosis and treatment of biliary-pancreatic diseases. ERCP-related complications total around 2.5% to 8%, with a mortality rate ranging from 0.5% to 1%. An exceptional ERCP complication is subcapsular hepatic hematoma, and few cases are reported worldwide.We present the case of a 52-year-old woman with a history of recurring upper abdominal pain and a clinical and ultrasonographic diagnosis of obstructive jaundice due to common bile duct stones. After 2 difficult endoscopic biliary procedures, common bile duct stones clearance was obtained. Post-ERCP course was symptomatic with upper abdominal pain and anemization with hemodynamic instability.CT scan demonstrated a 15 cm × 11 cm subcapsular hepatic hematoma filled with air and liquid on the surface of the right hepatic lobe. The patient was successfully treated with the embolization of a small branch of right hepatic artery angiographically identified as the cause of bleeding.Subcapsular hepatic hematoma after ERCP is a rare complication that must be taken into account in the differential diagnosis of symptomatic cases after ERCP. Its diagnosis is based on clinical and laboratory data and especially on imaging (ultrasound, CT, or MRI). Treatment is often conservative but, in some cases, embolization or percutaneous drainage or surgery may be necessary.
    MeSH term(s) Cholangiopancreatography, Endoscopic Retrograde/adverse effects ; Female ; Hematoma/etiology ; Humans ; Liver Diseases/etiology ; Middle Aged
    Language English
    Publishing date 2015-06-04
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000001041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Abdominal wall abscess secondary to spontaneous rupture of pyogenic liver abscess.

    Zizzo, Maurizio / Zaghi, Claudia / Manenti, Antonio / Luppi, Davide / Ugoletti, Lara / Bonilauri, Stefano

    International journal of surgery case reports

    2016  Volume 25, Page(s) 110–113

    Abstract: Introduction: Pyogenic liver abscess is a rare cause of hospitalization, related to a mortality rate ranging between 15% and 19%. Treatment of choice is represented by image-guided percutaneous drainage in combination with antibiotic therapy but, in ... ...

    Abstract Introduction: Pyogenic liver abscess is a rare cause of hospitalization, related to a mortality rate ranging between 15% and 19%. Treatment of choice is represented by image-guided percutaneous drainage in combination with antibiotic therapy but, in some selected cases, surgical treatment is necessary. In extremely rare cases, spontaneous rupture of liver abscess may occur, free in the peritoneal cavity or in neighboring organs, an event which is generally considered a surgical emergency.
    Presentation of case: A 95-years-old woman was hospitalized with fever, upper abdominal pain, mild dyspepsia and massive swelling of the anterior abdominal wall. Computed tomography revealed an oval mass located in the abdominal wall of 12cm×14cm×7cm, in continuity with an abscess of the left hepatic lobe. Because Proteus mirabilis was detected in both the liver abscess and the abdominal wall abscess, the patient was diagnosed with a ruptured pyogenic liver abscess. After spontaneous drainage to the exterior of the hepato-parietal abscess, she was successfully treated with antibiotics alone.
    Conclusion: Pyogenic liver abscess is a serious and life-threatening illness. Abscess rupture might occur. Many authors consider this complication a surgical emergency, but the site of abscess rupture changes the clinical history of the disease: in case of free rupture into the peritoneum, emergency surgery is mandatory, while a rupture localized in neighboring tissues or organs can be successfully treated by a combination of systemic antibiotics and fine needle aspiration and/or percutaneous drainage of the abscess.
    Language English
    Publishing date 2016-06-21
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2016.06.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Acute cholecystitis management in high-risk, critically ill, and unfit-for-surgery patients: the Italian Society of Emergency Surgery and Trauma (SICUT) guidelines.

    Coccolini, Federico / Cucinotta, Eugenio / Mingoli, Andrea / Zago, Mauro / Altieri, Gaia / Biloslavo, Alan / Caronna, Roberto / Cengeli, Ismail / Cicuttin, Enrico / Cirocchi, Roberto / Cobuccio, Luigi / Costa, Gianluca / Cozza, Valerio / Cremonini, Camilla / Del Vecchio, Giovanni / Dinatale, Giuseppe / Fico, Valeria / Galatioto, Christian / Kuriara, Hayato /
    Lacavalla, Domenico / La Greca, Antonio / Larghi, Alberto / Mariani, Diego / Mirco, Paolo / Occhionorelli, Savino / Parini, Dario / Polistina, Francesco / Rimbas, Mihai / Sapienza, Paolo / Tartaglia, Dario / Tropeano, Giuseppe / Venezia, Piero / Venezia, Dario Francesco / Zaghi, Claudia / Chiarugi, Massimo

    Updates in surgery

    2023  Volume 76, Issue 2, Page(s) 331–343

    Abstract: Dealing with acute cholecystitis in high-risk, critically ill, and unfit-for-surgery patients is frequent during daily practice and requires complex management. Several procedures exist to postpone and/or prevent surgical intervention in those patients ... ...

    Abstract Dealing with acute cholecystitis in high-risk, critically ill, and unfit-for-surgery patients is frequent during daily practice and requires complex management. Several procedures exist to postpone and/or prevent surgical intervention in those patients who temporarily or definitively cannot undergo surgery. After a systematic review of the literature, an expert panel from the Italian Society of Emergency Surgery and Trauma (SICUT) discussed the different issues and statements in subsequent rounds. The final version of the statements was discussed during the annual meeting in Rome (September 2022). The present paper presents the definitive conclusions of the discussion. Fifteen statements based on the literature evidence were provided. The statements gave precise indications regarding the decisional process and the management of patients who cannot temporarily or definitively undergo cholecystectomy for acute cholecystitis. Acute cholecystitis management in high-risk, critically ill, and unfit-for-surgery patients should be multidisciplinary. The different gallbladder drainage methods must be tailored according to each patient and based on the expertise of the hospital. Percutaneous gallbladder drainage is recommended as the first choice as a bridge to surgery or in severely physiologically deranged patients. Endoscopic gallbladder drainage (cholecystoduodenostomy and cholecystogastrostomy) is suggested as a second-line alternative especially as a definitive procedure for those patients not amenable to surgical management. Trans-papillary gallbladder drainage is the last option to be reserved only to those unfit for other techniques. Delayed laparoscopic cholecystectomy in patients with percutaneous gallbladder drainage is suggested in all those patients recovering from the conditions that previously discouraged surgical intervention after at least 6 weeks from the gallbladder drainage.
    MeSH term(s) Humans ; Critical Illness/therapy ; Cholecystitis, Acute/surgery ; Drainage/methods ; Cholecystectomy, Laparoscopic ; Italy ; Treatment Outcome
    Language English
    Publishing date 2023-12-28
    Publishing country Italy
    Document type Review ; Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-023-01729-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Development and Validation of a New Risk Score for Infection from COronavirus (SARS-CoV-2) [Ri.S.I.Co], that We Learned on the Field Treating Coronavirus Disease (COVID-19) Patients

    Fugazzola, Paola / Favi, Francesco / Tomason, Matteo / Zaghi, Claudia / Casadei, Chiara / Prosperi, Enrico / Sermonesi, Giacomo / Corbella, Davide / Coccolini, Federico / Praticò, Beniamino / Agnoletti, Vanni / Ansaloni, Luca

    SSRN Electronic Journal ; ISSN 1556-5068

    2020  

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.2139/ssrn.3588555
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Postoperative pain management in non-traumatic emergency general surgery: WSES-GAIS-SIAARTI-AAST guidelines.

    Coccolini, Federico / Corradi, Francesco / Sartelli, Massimo / Coimbra, Raul / Kryvoruchko, Igor A / Leppaniemi, Ari / Doklestic, Krstina / Bignami, Elena / Biancofiore, Giandomenico / Bala, Miklosh / Marco, Ceresoli / Damaskos, Dimitris / Biffl, Walt L / Fugazzola, Paola / Santonastaso, Domenico / Agnoletti, Vanni / Sbarbaro, Catia / Nacoti, Mirco / Hardcastle, Timothy C /
    Mariani, Diego / De Simone, Belinda / Tolonen, Matti / Ball, Chad / Podda, Mauro / Di Carlo, Isidoro / Di Saverio, Salomone / Navsaria, Pradeep / Bonavina, Luigi / Abu-Zidan, Fikri / Soreide, Kjetil / Fraga, Gustavo P / Carvalho, Vanessa Henriques / Batista, Sergio Faria / Hecker, Andreas / Cucchetti, Alessandro / Ercolani, Giorgio / Tartaglia, Dario / Galante, Joseph M / Wani, Imtiaz / Kurihara, Hayato / Tan, Edward / Litvin, Andrey / Melotti, Rita Maria / Sganga, Gabriele / Zoro, Tamara / Isirdi, Alessandro / De'Angelis, Nicola / Weber, Dieter G / Hodonou, Adrien M / tenBroek, Richard / Parini, Dario / Khan, Jim / Sbrana, Giovanni / Coniglio, Carlo / Giarratano, Antonino / Gratarola, Angelo / Zaghi, Claudia / Romeo, Oreste / Kelly, Michael / Forfori, Francesco / Chiarugi, Massimo / Moore, Ernest E / Catena, Fausto / Malbrain, Manu L N G

    World journal of emergency surgery : WJES

    2022  Volume 17, Issue 1, Page(s) 50

    Abstract: Background: Non-traumatic emergency general surgery involves a heterogeneous population that may present with several underlying diseases. Timeous emergency surgical treatment should be supplemented with high-quality perioperative care, ideally ... ...

    Abstract Background: Non-traumatic emergency general surgery involves a heterogeneous population that may present with several underlying diseases. Timeous emergency surgical treatment should be supplemented with high-quality perioperative care, ideally performed by multidisciplinary teams trained to identify and handle complex postoperative courses. Uncontrolled or poorly controlled acute postoperative pain may result in significant complications. While pain management after elective surgery has been standardized in perioperative pathways, the traditional perioperative treatment of patients undergoing emergency surgery is often a haphazard practice. The present recommended pain management guidelines are for pain management after non-traumatic emergency surgical intervention. It is meant to provide clinicians a list of indications to prescribe the optimal analgesics even in the absence of a multidisciplinary pain team.
    Material and methods: An international expert panel discussed the different issues in subsequent rounds. Four international recognized scientific societies: World Society of Emergency Surgery (WSES), Global Alliance for Infection in Surgery (GAIS), Italian Society of Anesthesia, Analgesia Intensive Care (SIAARTI), and American Association for the Surgery of Trauma (AAST), endorsed the project and approved the final manuscript.
    Conclusion: Dealing with acute postoperative pain in the emergency abdominal surgery setting is complex, requires special attention, and should be multidisciplinary. Several tools are available, and their combination is mandatory whenever is possible. Analgesic approach to the various situations and conditions should be patient based and tailored according to procedure, pathology, age, response, and available expertise. A better understanding of the patho-mechanisms of postoperative pain for short- and long-term outcomes is necessary to improve prophylactic and treatment strategies.
    MeSH term(s) Abdomen ; Analgesics ; Anesthesia ; Humans ; Pain, Postoperative/drug therapy ; Perioperative Care ; United States
    Chemical Substances Analgesics
    Language English
    Publishing date 2022-09-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2233734-9
    ISSN 1749-7922 ; 1749-7922
    ISSN (online) 1749-7922
    ISSN 1749-7922
    DOI 10.1186/s13017-022-00455-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Aortic balloon occlusion (REBOA) in pelvic ring injuries: preliminary results of the ABO Trauma Registry.

    Coccolini, Federico / Ceresoli, Marco / McGreevy, David T / Sadeghi, Mitra / Pirouzram, Artai / Toivola, Asko / Skoog, Per / Idoguchi, Koji / Kon, Yuri / Ishida, Tokiya / Matsumura, Yosuke / Matsumoto, Junichi / Reva, Viktor / Maszkowski, Mariusz / Fugazzola, Paola / Tomasoni, Matteo / Cicuttin, Enrico / Ansaloni, Luca / Zaghi, Claudia /
    Sibilla, Maria Grazia / Cremonini, Camilla / Bersztel, Adam / Caragounis, Eva-Corina / Falkenberg, Mårten / Handolin, Lauri / Oosthuizen, George / Szarka, Endre / Manchev, Vassil / Wannatoop, Tongporn / Chang, Sung Wook / Kessel, Boris / Hebron, Dan / Shaked, Gad / Bala, Miklosh / Ordoñez, Carlos A / Hibert-Carius, Peter / Chiarugi, Massimo / Nilsson, Kristofer F / Larzon, Thomas / Gamberini, Emiliano / Agnoletti, Vanni / Catena, Fausto / Hörer, Tal M

    Updates in surgery

    2020  Volume 72, Issue 2, Page(s) 527–536

    Abstract: EndoVascular and Hybrid Trauma Management (EVTM) has been recently introduced in the treatment of severe pelvic ring injuries. This multimodal method of hemorrhage management counts on several strategies such as the REBOA (resuscitative endovascular ... ...

    Abstract EndoVascular and Hybrid Trauma Management (EVTM) has been recently introduced in the treatment of severe pelvic ring injuries. This multimodal method of hemorrhage management counts on several strategies such as the REBOA (resuscitative endovascular balloon occlusion of the aorta). Few data exist on the use of REBOA in patients with a severely injured pelvic ring. The ABO (aortic balloon occlusion) Trauma Registry is designed to capture data for all trauma patients in hemorrhagic shock where management includes REBOA placement. Among all patients included in the ABO registry, 72 patients presented with severe pelvic injuries and were the population under exam. 66.7% were male. Mean and median ISS were respectively 43 and 41 (SD ± 13). Isolated pelvic injuries were observed in 12 patients (16.7%). Blunt trauma occurred in 68 patients (94.4%), penetrating in 2 (2.8%) and combined in 2 (2.8%). Type of injury: fall from height in 15 patients (23.1%), traffic accident in 49 patients (75.4%), and unspecified impact in 1 patient (1.5%). Femoral access was gained pre-hospital in 1 patient, in emergency room in 43, in operating room in 12 and in angio-suite in 16. REBOA was positioned in zone 1 in 59 patients (81,9%), in zone 2 in 1 (1,4%) and in zone 3 in 12 (16,7%). Aortic occlusion was partial/periodical in 35 patients (48,6%) and total occlusion in 37 patients (51,4%). REBOA associated morbidity rate: 11.1%. Overall mortality rate was 54.2% and early mortality rate (≤ 24 h) was 44.4%. In the univariate analysis, factors related to early mortality (≤ 24 h) are lower pH values (p = 0.03), higher base deficit (p = 0.021), longer INR (p = 0.012), minor increase in systolic blood pressure after the REBOA inflation (p = 0.03) and total aortic occlusion (p = 0.008). None of these values resulted significant in the multivariate analysis. In severe hemodynamically unstable pelvic trauma management, REBOA is a viable option when utilized in experienced centers as a bridge to other treatments; its use might be, however, accompanied with severe-to-lethal complications.
    MeSH term(s) Adolescent ; Adult ; Aorta ; Arterial Occlusive Diseases/etiology ; Arterial Occlusive Diseases/therapy ; Balloon Occlusion/adverse effects ; Balloon Occlusion/methods ; Female ; Humans ; Hydrogen-Ion Concentration ; International Normalized Ratio ; Male ; Middle Aged ; Pelvis/injuries ; Registries ; Shock, Hemorrhagic/etiology ; Shock, Hemorrhagic/mortality ; Shock, Hemorrhagic/therapy ; Systole ; Trauma Severity Indices ; Young Adult
    Language English
    Publishing date 2020-03-04
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-020-00735-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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