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  1. Article ; Online: Interleukin-10 may have diagnostic value in identifying mild traumatic brain injury.

    Zakariaei, Zakaria

    Brain injury

    2020  Volume 34, Issue 4, Page(s) 591–592

    MeSH term(s) Brain Concussion ; Brain Injuries/diagnosis ; Humans ; Interleukin-10
    Chemical Substances Interleukin-10 (130068-27-8)
    Language English
    Publishing date 2020-02-12
    Publishing country England
    Document type Letter
    ZDB-ID 639115-1
    ISSN 1362-301X ; 0269-9052
    ISSN (online) 1362-301X
    ISSN 0269-9052
    DOI 10.1080/02699052.2020.1725128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2242: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Silymarin as a Promising Potential Therapeutic Agent for Treatment of Patients with Paraquat Poisoning: An Issue that Merits Further Research.

    Zakariaei, Zakaria

    Advanced journal of emergency medicine

    2019  Volume 4, Issue 2, Page(s) e16

    Language English
    Publishing date 2019-09-29
    Publishing country Iran
    Document type Journal Article
    ISSN 2588-400X
    ISSN (online) 2588-400X
    DOI 10.22114/ajem.v0i0.266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Management of organophosphorus poisoning and the role of magnesium sulfate: A scoping review of literature.

    Nekoukar, Zahra / Talabaki, Homa / Zakariaei, Zakaria / Mesri, Mahdi / Azadeh, Hossein

    Clinical and experimental emergency medicine

    2024  

    Abstract: Organophosphorus agents are easily absorbed via respiratory, gastrointestinal, and dermal routes, and inhibit the acetylcholine transferase enzyme (AChE), which is responsible for the majority of toxicity caused by organophosphates in the body. A ... ...

    Abstract Organophosphorus agents are easily absorbed via respiratory, gastrointestinal, and dermal routes, and inhibit the acetylcholine transferase enzyme (AChE), which is responsible for the majority of toxicity caused by organophosphates in the body. A comprehensive search was conducted across three prominent databases, namely Google Scholar, PubMed, and Science Direct, to identify relevant articles published. The search focused on the keywords "MgSO4" or "magnesium sulfate" in conjunction with "organophosphate" or "organophosphate poisoning." Inhibition of AChE results in the accumulation of acetylcholine (ACh) in synapses and stimulation of cholinergic receptors. Considering that several studies have shown the use of magnesium sulfate (MgSO4) in inhibiting the release of ACh in the central and peripheral sympathetic and parasympathetic synapses, this study was conducted to review the role of MgSO4 in the treatment of OP. The intravenous administration of MgSO4 exhibits favorable tolerability and clinical efficacy in alleviating cardiac toxicity associated with OP exposure.
    Language English
    Publishing date 2024-04-05
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2383-4625
    ISSN 2383-4625
    DOI 10.15441/ceem.23.179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Massive intracerebral hemorrhage following methamphetamine poisoning in a man: A case report.

    Banimostafavi, Elham Sadat / Taheri, Amirmasoud / Malakian, Abdollah / Zakariaei, Zakaria

    International journal of surgery case reports

    2024  Volume 117, Page(s) 109489

    Abstract: Introduction and importance: Methamphetamine (MAP) is a highly addictive stimulant known to have detrimental effects on the brain and various physiological systems, including an elevation in heart rate and blood pressure. Additionally, MAP use has been ... ...

    Abstract Introduction and importance: Methamphetamine (MAP) is a highly addictive stimulant known to have detrimental effects on the brain and various physiological systems, including an elevation in heart rate and blood pressure. Additionally, MAP use has been linked to the development of intracerebral hemorrhage (ICH), a serious and potentially fatal condition that is notably prevalent among young individuals.
    Case presentation: We present the case of a 42-year-old man who suffered a massive ICH due to hypertension resulting from MAP poisoning. The patient presented with symptoms of nausea, vomiting, and blurred vision for around two hours following the accidental inhalation of MAP. However, his condition was significantly improved through the implementation of neurosurgical intervention.
    Clinical discussion: In recent years, the misuse of MAP among young adults has raised concerns about its association with ICH. ICH is a type of stroke where a blood vessel in the brain ruptures due to high blood pressure, causing bleeding. This medical emergency can lead to various symptoms, such as severe headaches, loss of consciousness, and paralysis. ICH is indeed a serious and life-threatening condition that necessitates prompt medical attention. It can also lead to long-term adverse effects for the individual affected.
    Conclusions: The association with ICH and MAP abuse among young adults is a substantial public health issue. To gain a comprehensive understanding of the mechanisms underlying MAP abuse-induced elevation of ICH risk, further exploration is necessary.
    Language English
    Publishing date 2024-03-14
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2024.109489
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Tramadol poisoning and its management and complications: a scoping review.

    Manouchehri, Aliasghar / Nekoukar, Zahra / Malakian, Abdollah / Zakariaei, Zakaria

    Annals of medicine and surgery (2012)

    2023  Volume 85, Issue 8, Page(s) 3982–3989

    Abstract: Tramadol (TR) is an opioid agonist (μ-opioid receptors) that also affects the noradrenergic and serotonergic systems. TR is a synthetic analgesic substance with opioid agonist properties that has been approved for pain management by affecting the central ...

    Abstract Tramadol (TR) is an opioid agonist (μ-opioid receptors) that also affects the noradrenergic and serotonergic systems. TR is a synthetic analgesic substance with opioid agonist properties that has been approved for pain management by affecting the central nervous system.
    Objective: The primary objective of this scoping review was to determine the poisoning consequences of TR and its associated symptom management techniques, as well as its effect on opioid and non-opioid receptors, metabolism, and complications on various organ systems.
    Discussion: Typically, acute overdose of TR is not considered life threatening, and most fatalities are attributed to polysubstance overdose. TR can cause drowsiness, headaches, seizures, respiratory depression, low heart rate, coma, and even death. Additionally, the prolonged use of TR can lead to addiction, with withdrawal resulting in both common and atypical symptoms.
    Conclusions: Therefore, it is recommended that patients with TR poisoning receive close monitoring of their cardiovascular system, along with a comprehensive management plan for their levels of consciousness and respiratory function.
    Language English
    Publishing date 2023-07-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1097/MS9.0000000000001075
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  6. Article: Severe metabolic acidosis due to massive metformin overdose in a man: a case report.

    Manouchehri, Aliasghar / Rashidian, Hale / Zakariaei, Zakaria

    Oxford medical case reports

    2023  Volume 2023, Issue 5, Page(s) omad049

    Abstract: Metformin-associated lactic acidosis is an extremely unusual but potentially life-threatening condition. This condition is typically observed in individuals who are suicidal or have type II diabetes mellitus (DM) and have taken an overdose of metformin. ... ...

    Abstract Metformin-associated lactic acidosis is an extremely unusual but potentially life-threatening condition. This condition is typically observed in individuals who are suicidal or have type II diabetes mellitus (DM) and have taken an overdose of metformin. In this case, we present the instance of a 43-year-old man who had type II DM and was addicted to oral opium. Following a suicide attempt with an overdose of metformin, he experienced symptoms such as nausea, vomiting, weakness and lactic acidosis. However, prompt and effective treatment was administered, including hemodialysis and adequate hemodynamic resuscitation, leading to a successful outcome.
    Language English
    Publishing date 2023-05-30
    Publishing country England
    Document type Case Reports
    ZDB-ID 2766251-2
    ISSN 2053-8855
    ISSN 2053-8855
    DOI 10.1093/omcr/omad049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Fatal outcome due to aluminum phosphide poisoning in an old man with a psychiatric disorder as a latent post-COVID-19 challenge: A case report.

    Sadeghi, Mahdieh / Zakariaei, Zakaria / Rashidian, Hale / Soleymani, Mostafa

    SAGE open medical case reports

    2023  Volume 11, Page(s) 2050313X231177759

    Abstract: Aluminum phosphide is a metal phosphide widely implemented as a pesticide. In the country of Iran, it is recognized by the colloquial name of rice pill. Any trace of accidental or intentional ingestion of aluminum phosphidecan result in severe ... ...

    Abstract Aluminum phosphide is a metal phosphide widely implemented as a pesticide. In the country of Iran, it is recognized by the colloquial name of rice pill. Any trace of accidental or intentional ingestion of aluminum phosphidecan result in severe hemodynamic disorders and metabolic acidosis, ultimately leading to the patient's mortality. In this report, we document the unfortunate demise of an 85-year-old man who lived in isolation, having lost his wife to COVID-19. The patient consumed aluminum phosphide tablets and, despite resuscitation efforts, inevitably succumbed to the toxic effects.
    Language English
    Publishing date 2023-06-06
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X231177759
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Accidental vitamin D3 overdose in a young man.

    Nekoukar, Zahra / Manouchehri, Aliasghar / Zakariaei, Zakaria

    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition

    2023  Volume 94, Issue 2, Page(s) 82–85

    Abstract: Vitamin D3 (VD3) is a fat-soluble vitamin that can accumulate in the body and lead to toxicity by increasing 25(OH) D levels when consumed in large amounts. Maintaining 25(OH) D levels greater than 30 ng/mL is crucial for overall health due to the ... ...

    Abstract Vitamin D3 (VD3) is a fat-soluble vitamin that can accumulate in the body and lead to toxicity by increasing 25(OH) D levels when consumed in large amounts. Maintaining 25(OH) D levels greater than 30 ng/mL is crucial for overall health due to the significant role of vitamin D in the body. The most common causes of VD3 intoxication are manufacturing errors or self-administration. Currently, there is no definitive data on the dose and duration of VD3 consumption that leads to toxicity. The maximum daily doses of VD3 that can be tolerated without causing adverse effects are not established. The maximum recommended amount for long-term supplementation is 2,000 units per day. Vitamin D3 toxicity (VDT) can present in various scenarios, ranging from asymptomatic to gastrointestinal, and in severe cases with neuropsychiatric and life-threatening symptoms. We report the case of a 29-year-old man who presented with symptoms of VDT following an accidental overdose of VD3 over 2 weeks.
    MeSH term(s) Male ; Humans ; Adult ; Cholecalciferol ; Vitamin D ; Vitamins
    Chemical Substances Cholecalciferol (1C6V77QF41) ; Vitamin D (1406-16-2) ; Vitamins
    Language English
    Publishing date 2023-11-17
    Publishing country Switzerland
    Document type Case Reports ; News
    ZDB-ID 120692-8
    ISSN 0300-9831
    ISSN 0300-9831
    DOI 10.1024/0300-9831/a000798
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.210: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Potential Association Between Latent

    Fakhar, Mahdi / Montazeri, Mahbobeh / Nakhaei, Maryam / Soleymani, Mostafa / Zakariaei, Zakaria / Abbasi, Ali / Solaymani, Eissa

    Foodborne pathogens and disease

    2024  

    Abstract: Toxoplasma ... ...

    Abstract Toxoplasma gondii
    Language English
    Publishing date 2024-04-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2148479-X
    ISSN 1556-7125 ; 1535-3141
    ISSN (online) 1556-7125
    ISSN 1535-3141
    DOI 10.1089/fpd.2023.0087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7517: Show issues

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  10. Article: Epidemiological Aspects of Opioid Poisoning in Northern Iran: A Registry-Based Clinical Study.

    Ramezanzadeh, Hamed / Khosravi, Navid / Hosseininejad, Seyed Mohammad / Mahmoodi, Mahboobe / Zakariaei, Zakaria / Sadeghi, Mahdieh

    Health services insights

    2024  Volume 17, Page(s) 11786329241232300

    Abstract: Opioids are a class of drugs that are commonly used to manage pain due to their analgesic and sedative effects. However, the high consumption of opioids in the community has led to an increase in the incidence of overdoses and poisonings caused by ... ...

    Abstract Opioids are a class of drugs that are commonly used to manage pain due to their analgesic and sedative effects. However, the high consumption of opioids in the community has led to an increase in the incidence of overdoses and poisonings caused by various types of these drugs, whether intentional or unintentional. Therefore, comprehending the epidemiological features of patients experiencing opioid poisoning is crucial. We decided to investigate various epidemiological aspects of patients with opioid poisoning in the Mazandaran province, located in northern Iran, during the period of 2020 to 2021. The present investigation was conducted as a descriptive cross-sectional study, wherein we collected data on patients registered in the Mazandaran Registry Center of Opioid Poisoning (MRCOP) who had a history of using any kind of opioid. We collected information on various parameters, including patient demographics, the type of opioid consumed, the mode of consumption, and clinical outcomes. A total of 240 patients were initially registered at the registry center. However, 17 cases were excluded with personal consent, and eventually, a total of 223 patients were included in the investigation. The majority of the patients 70.9% (n = 158) were male, and the average age was 34.4 ± 16.55 years. The most common cause of poisoning reported in our study was intentional, which was mainly due to a suicide attempt. Furthermore, the most prevalent type of opioid consumed was methadone. The most frequently observed symptoms of poisoning among the patients were drowsiness, a decreased level of consciousness, and reduced arterial oxygen saturation levels. Based on the results of our study, several factors were found to be significant in methadone poisoning, including addiction, age, gender, suicide attempt, and a history of psychiatric disorder. These findings highlight the need for public education and awareness campaigns on the risks associated with opioid use, particularly methadone.
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2803340-1
    ISSN 1178-6329
    ISSN 1178-6329
    DOI 10.1177/11786329241232300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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