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Article: Multimodal identification of rare potent effector CD8 T cells in solid tumors.

Ray, Arja / Bassette, Molly / Hu, Kenneth H / Pass, Lomax F / Samad, Bushra / Combes, Alexis / Johri, Vrinda / Davidson, Brittany / Hernandez, Grace / Zaleta-Linares, Itzia / Krummel, Matthew F

bioRxiv : the preprint server for biology

2023  

Abstract: Antitumor immunity is driven by CD8 T cells, yet we lack signatures for the exceptional effectors in tumors, amongst the vast majority of CD8 T cells undergoing exhaustion. By leveraging the measurement of a canonical T cell activation protein (CD69) ... ...

Abstract Antitumor immunity is driven by CD8 T cells, yet we lack signatures for the exceptional effectors in tumors, amongst the vast majority of CD8 T cells undergoing exhaustion. By leveraging the measurement of a canonical T cell activation protein (CD69) together with its RNA (
Language English
Publishing date 2023-09-28
Publishing country United States
Document type Preprint
DOI 10.1101/2023.09.26.559470
Database MEDical Literature Analysis and Retrieval System OnLINE

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