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  1. Article ; Online: Deep venous thrombosis post mechanical thrombectomy in acute ischaemic stroke.

    Nevajda, Branimir / Amin, Jigisha / Zaman, Ali / Bhogal, Paul

    BMJ case reports

    2023  Volume 16, Issue 8

    Abstract: A woman in her 20s presented with neck pain, slurred speech and left-sided weakness. She successfully underwent mechanical thrombectomy (MT) for total occlusion of the basilar artery and made full neurological recovery. Initial ultrasound Doppler of legs ...

    Abstract A woman in her 20s presented with neck pain, slurred speech and left-sided weakness. She successfully underwent mechanical thrombectomy (MT) for total occlusion of the basilar artery and made full neurological recovery. Initial ultrasound Doppler of legs (USDL) did not show any deep vein thrombosis (DVT). However, 2 days later, a repeat USDL revealed an extensive proximal DVT in the right common femoral vein. CT scan confirmed a haematoma arising from the femoral access site causing compression of the adjacent common femoral vein. This may have initiated DVT formation or exacerbated extension of a previously undetected DVT. Echocardiogram revealed a patent foramen ovale. As the patient was asymptomatic, delayed or missed diagnosis of DVT would have put her at risk of life-threatening pulmonary embolism or further strokes. Clinicians should maintain a high index of suspicion of DVT as a direct procedural complication from MT so treatment can be initiated promptly.
    MeSH term(s) Female ; Humans ; Stroke/etiology ; Brain Ischemia/diagnostic imaging ; Brain Ischemia/etiology ; Ischemic Stroke ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/etiology ; Thrombectomy
    Language English
    Publishing date 2023-08-21
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-255391
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  2. Article ; Online: Biomass-Derived Adsorbents for Dye and Heavy Metal Removal from Wastewater

    Kashir Ali / Muhammad Ussama Javaid / Zaman Ali / Muhammad Junaid Zaghum

    Adsorption Science & Technology, Vol

    2021  Volume 2021

    Abstract: Wastewater has a high concentration of dyes and heavy metals, which are the two most significant contaminants. Due to their high toxicity and vulnerability, they possess a potential threat to human health as well as the ecosystem. There are many ways to ... ...

    Abstract Wastewater has a high concentration of dyes and heavy metals, which are the two most significant contaminants. Due to their high toxicity and vulnerability, they possess a potential threat to human health as well as the ecosystem. There are many ways to eliminate these pollutants from water but adsorption has attained much interest because of its low cost, easy application, and no secondary pollutants. Biomass is considered an ecological burden and a reason for the reduction in the earth’s carrying capacity. These materials may be used as cost-effective adsorbents to remove dyes and heavy metals from wastewater. This paper highlights recent advances made in dye and heavy metal adsorption in the last 10 years. The prime focus of this review paper is on the direct application of these biomasses without any chemical or physical alteration. The removal efficiencies and adsorption capabilities of different biomass-derived adsorbents for the removal of dyes and heavy metals from wastewater are summarised in this study. Additionally, the adsorption mechanisms underlying the removal of dyes and heavy metals using biomass-derived adsorbents have been discussed, with a focus on two kinetic models: pseudofirst-order and pseudosecond-order. Furthermore, the Langmuir and Freundlich isotherms were utilised to verify the experimental findings and to quantify the amount and degree of adsorption favorability. Based on what has been covered in the literature, the conclusion has been drawn. The future research needs are proposed in the area of biomass-derived adsorbent development, their modification for improved efficiencies, and application on large-scale wastewater treatment plants.
    Keywords Physical and theoretical chemistry ; QD450-801
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Hindawi - SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Radon concentration in spring water as an indicator of seismic activity: a case study of the Muzaffarabad Fault in Pakistan.

    Abbas, Sayed Qamar / Khan, Jahanzeb / Riaz, Muhammad Tayyib / Rafique, Muhammad / Zaman, Ali / Khan, Sajjad

    Environmental monitoring and assessment

    2023  Volume 196, Issue 1, Page(s) 41

    Abstract: Radon and its progenies found in water indicate the existence of seismically active faults in the region. However, exposure to high levels of radon can also result in radiation-related health risks. This study focuses on radon-based active tectonic ... ...

    Abstract Radon and its progenies found in water indicate the existence of seismically active faults in the region. However, exposure to high levels of radon can also result in radiation-related health risks. This study focuses on radon-based active tectonic studies along the Muzaffarabad Fault in the core of the Hazara-Kashmir Syntaxis (HKS), NW Himalayas, Pakistan. In this study, spring water samples were collected along roadside of Jhelum Valley and in close proximity to the Muzaffarabad Fault in Pakistan using Radon Thoron Monitor (RTM1688-2). The results of the study showed that the radon concentrations in the water samples ranged from 1.895 to 17.097 Bq/l. The study found that the highest radon concentration was observed in the samples collected closest to the fault, while the lowest concentration was observed in the samples collected further away. The statistical analysis between the radon concentration and the distance from the fault showed a strong inverse relationship (R
    MeSH term(s) Radon/analysis ; Water/analysis ; Pakistan ; Radiation Monitoring ; Earthquakes ; Water Pollutants, Radioactive/analysis
    Chemical Substances Radon (Q74S4N8N1G) ; Water (059QF0KO0R) ; Water Pollutants, Radioactive
    Language English
    Publishing date 2023-12-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 782621-7
    ISSN 1573-2959 ; 0167-6369
    ISSN (online) 1573-2959
    ISSN 0167-6369
    DOI 10.1007/s10661-023-12235-0
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  4. Article: In vitro evaluation of herbal based Lesh Nat B cream against

    Gul, Sahiba / Khan, Momin / Amin, Adnan / Zaman, Ali / Said, Arsalan / Iqbal, Aamir / Muhammad, Sher / Khan, Rahat Ullah

    Journal of parasitic diseases : official organ of the Indian Society for Parasitology

    2023  Volume 47, Issue 3, Page(s) 664–670

    Abstract: Pentavalent antimonials continue to be the standard treatment for cutaneous leishmaniasis. But their use is retarded owing to highly-priced, prolonged hospitalization, noxious and poor solubility. Therefore, there is a dire need to characterize new ... ...

    Abstract Pentavalent antimonials continue to be the standard treatment for cutaneous leishmaniasis. But their use is retarded owing to highly-priced, prolonged hospitalization, noxious and poor solubility. Therefore, there is a dire need to characterize new potential compounds possessing anti-leishmanial activity. Topical therapies that are more successful are an essential alternative therapeutic option for the localized self-limiting form of this disease. We tested the herbal-based topical cream Lesh Nat B against
    Language English
    Publishing date 2023-06-25
    Publishing country India
    Document type Journal Article
    ZDB-ID 2548456-4
    ISSN 0975-0703 ; 0971-7196
    ISSN (online) 0975-0703
    ISSN 0971-7196
    DOI 10.1007/s12639-023-01611-9
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  5. Article: Novel Schiff bases of Vanillin: potent inhibitors of macrophage harbored

    Ur Rahman, Mujeeb / Khan, Momin / Khan, Sher Wali / Khan, Rahat Ullah / Sohail, Aamir / Zaman, Ali / Alam, Naveed

    Journal of parasitic diseases : official organ of the Indian Society for Parasitology

    2023  Volume 47, Issue 3, Page(s) 619–629

    Abstract: Due to limited chemotherapeutic options for leishmaniasis, novel synthetic compounds are gaining attention for evaluation against leishmaniasis. This study aimed to synthesize the compound's Schiff bases of Vanillin to investigate and evaluate their anti- ...

    Abstract Due to limited chemotherapeutic options for leishmaniasis, novel synthetic compounds are gaining attention for evaluation against leishmaniasis. This study aimed to synthesize the compound's Schiff bases of Vanillin to investigate and evaluate their anti-leishmanial potentials against intracellular protozoan parasites
    Language English
    Publishing date 2023-06-13
    Publishing country India
    Document type Journal Article
    ZDB-ID 2548456-4
    ISSN 0975-0703 ; 0971-7196
    ISSN (online) 0975-0703
    ISSN 0971-7196
    DOI 10.1007/s12639-023-01594-7
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  6. Article ; Conference proceedings: Early Feeding after Radiologically Inserted Gastrostomy (RIG) Insertion: A 5-Year Audit

    Zaman, Ali Ashrafuz / Hasani, Hannah / Chow, Katarina / Moghal, Sakib / Ahmed, Rumman

    The Arab Journal of Interventional Radiology

    2023  Volume 07, Issue S 01

    Event/congress PAIRS 2023 Annual Congress, Grand Hyatt Hotel, Dubai, UAE, 2023-02-11
    Language English
    Publishing date 2023-02-01
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ISSN 2542-7083 ; 2542-7075
    ISSN (online) 2542-7083
    ISSN 2542-7075
    DOI 10.1055/s-0043-1763422
    Database Thieme publisher's database

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  7. Thesis ; Online: Hvilke faktorer bidrar til SARS-CoV-2 sin spredningsevne?

    Hauger, Christian Farbrot / Ruud, Herman Sundet / Zaman, Ali

    2020  

    Abstract: I denne oppgaven har det blitt forsøkt å samle informasjon om faktorer som bidrar til SARS-CoV-2 sin spredningsevne. Som metodevalg er litteratursøk med bruk av over 20 vitenskapelige artikler benyttet. SARS-CoV-2 tilhører gruppen IV i Baltimore- ... ...

    Abstract I denne oppgaven har det blitt forsøkt å samle informasjon om faktorer som bidrar til SARS-CoV-2 sin spredningsevne. Som metodevalg er litteratursøk med bruk av over 20 vitenskapelige artikler benyttet. SARS-CoV-2 tilhører gruppen IV i Baltimore-klassifikasjonen over virus. Det antydes at viruset stammer originalt fra kinesisk flaggermus, men det er sannsynligvis intermediære smittekilder som førte smitten til mennesker. Såpe ser ut til å være en svært effektiv måte å inaktivere SARS-CoV-2 på hudoverflater. Det samme er desinfeksjonsmiddel, men det har ulemper som at man trenger større mengde desinfeksjonsmiddel enn såpe for å dekke de samme områdene. Inkubasjonstiden til SARS-Cov-2 for å bli symptomatisk sykdom er mellom 2 - 14 dager, med gjennomsnittet mellom 5 - 6 dager. Dette stemmer godt overens med beskjeder fra offentlige helsetjenester som FHI og WHO. SARS-CoV-2 forårsaker sykdommen COVID-19. I noen sykdomsforløp vil personer være asymptomatiske, men fortsatt kunne spre viruset til andre. Det kan spres ved direkte- og indirekte kontakt eller via aerosoler. SARS-CoV-2 ser ut til å binde seg til ACE2-reseptorer. I tillegg er det sannsynlig at viruset er avhengig av TMPRSS2 for bearbeiding av S-protein for å infisere mennesker. Det ser ut til at blodtrykksmedisin ikke fører til lettere infeksjon med SARS-CoV-2 hos eldre, da det ikke er forskning som tilsier dette. Virusets spredning er sannsynligvis fremmet pga. høy menneskelig mobilitet i sammenheng med vårfestivalen i Kina, mangel på effektiv håndvask, potensielt svært høy affinitet til ACE2-reseptorer, og uvitende, udokumenterte smittede som sprer viruset.

    In this thesis there has been an attempt to gather information about contributing factors to the spread of SARS-CoV-2. As method selection, literature search with over 20 scientific articles was used to find the required information. SARS-CoV-2 belongs to the group IV in the Baltimore classification of viruses. It appears that the virus originated from Chinese bats, however it is likely that intermediate sources were the reason it led to transmission to humans. Soap appears to be a very efficient way to inactivate SARS-CoV-2 on the surface of the skin. Disinfectant has the same effect; however, it has some flaws, such as the need of a bigger quantity of disinfectant to cover the same areas as soap. The incubation period of SARS-CoV-2 to become a symptomatic disease is between 2 - 14 days, with the median being between 5 - 6 days. This is in consensus with messages from public health services such as FHI and WHO. SARS-CoV-2 causes the disease COVID-19. In some infection cases humans will be asymptomatic, but will still have the ability to infect others. It can be spread by direct- and indirect contact or by aerosols. SARS-CoV-2 appears to connect to ACE2-receptors. In addition, it is likely that the virus depends on TMPRSS2 for priming of the S-protein to infect humans. It seems that medication for treatment of high blood pressure does not correlate to a higher chance of getting infected with SARS-CoV-2. The spread of the virus is likely promoted by factors like high human mobility, in relation to the spring festival in China, the lack of effective hand washing, potentially very high affinity to ACE2-receptors, and ignorant, undocumented infected people that spread the virus.
    Keywords covid19
    Subject code 306
    Publisher NTNU
    Publishing country no
    Document type Thesis ; Online
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  8. Article ; Online: Acute Arterial Occlusion Following ChAdOx1 nCov-19 (Oxford-AstraZeneca) Vaccination.

    Ali, Azhar / Rabouhans, Jeremy / Salar, Tooba / Moghul, Sakib / Makkuni, Sudhakaran / Browne, Tom / Ahmed, Rumman / Syed, Imran / Zaman, Ali

    Cardiovascular and interventional radiology

    2022  Volume 45, Issue 3, Page(s) 398–401

    MeSH term(s) Acute Disease ; COVID-19/prevention & control ; ChAdOx1 nCoV-19 ; Humans ; Vaccination
    Chemical Substances ChAdOx1 nCoV-19 (B5S3K2V0G8)
    Language English
    Publishing date 2022-01-18
    Publishing country United States
    Document type Letter
    ZDB-ID 603082-8
    ISSN 1432-086X ; 0342-7196 ; 0174-1551
    ISSN (online) 1432-086X
    ISSN 0342-7196 ; 0174-1551
    DOI 10.1007/s00270-021-03053-3
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1378: Show issues Location:
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  9. Article ; Online: Studies on effects of umbelliferon derivatives against periodontal bacteria; antibiofilm, inhibition of quorum sensing and molecular docking analysis.

    Amin, Adnan / Hanif, Muhammad / Abbas, Khizar / Ramzan, Muhammad / Rasheed, Abdur / Zaman, Ali / Pieters, Luc

    Microbial pathogenesis

    2020  Volume 144, Page(s) 104184

    Abstract: Objective: Umbelliferon derivatives are exclusively found in plants of Ferula spp. that are commonly used in curing various health concerns related to oral cavity. Diabetic patient are especially effected with periodontitis and allied complications.: ... ...

    Abstract Objective: Umbelliferon derivatives are exclusively found in plants of Ferula spp. that are commonly used in curing various health concerns related to oral cavity. Diabetic patient are especially effected with periodontitis and allied complications.
    Method: We investigated various compounds isolated from Ferula narthex exudate against clinical strains obtained from diabetic patients with periodontitis. Further antibiofilm, antiquorum sensing and molecular docking studies and ADMET analysis were performed.
    Results: The docking target included 2Q0J, 2UV0, 3QP5 and 3QP1. HYDE affinity assessment was performed for the first 30 top ranking docked conformations within these active sites. The binding free energy ΔG, FlexX docking score and the most favorable poses for all the compounds were determined. During in vitro analysis, feselol presented high inhibition of Pseudomonas aeruginosa (MIC 0.01 mg/mL, MBC 0.02 mg/mL). Similarly, Feselol presented significant inhibition against clinical strain S. epidermidis (MIC 0.087 mg/mL, MBC 0.174 mg/mL) and S. aureus (MIC 0.087 mg/mL, MBC 0.087 mg/mL) preceded by 10'-R-acetyl-karatavacinol against S. epidermidis (MIC 0.56 mg/mL, MBC 0.56 mg/mL) and S. aureus (MIC 0.28 mg/mL, MBC 0.28 mg/mL). During antibiofilm inhibition assay, 10' R-acetyl-karatavacinol showed significant inhibition (54% at a final concentration 0.45 mg/mL), whereas slight antiquorum sensing activity was recorded.
    Conclusions: The umbelliferon derivatives have significant inhibition of clinical isolates and moderate antibiofilm potential.
    MeSH term(s) Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Bacteria/drug effects ; Biofilms/drug effects ; Ferula/chemistry ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Pseudomonas aeruginosa/drug effects ; Quorum Sensing/drug effects ; Staphylococcus aureus/drug effects ; Umbelliferones/chemistry ; Umbelliferones/pharmacology
    Chemical Substances Anti-Bacterial Agents ; Plant Extracts ; Umbelliferones ; 7-hydroxycoumarin (60Z60NTL4G)
    Language English
    Publishing date 2020-04-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 632772-2
    ISSN 1096-1208 ; 0882-4010
    ISSN (online) 1096-1208
    ISSN 0882-4010
    DOI 10.1016/j.micpath.2020.104184
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2136: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article ; Online: Inhibitive efficacy of Nymphoides indica rhizome extract on α-glucosidase, and cross-link formation of advanced glycation end product.

    Hanif, Muhammad / Khan, Muzammil-Ahmad / Rafey, Muhammad-Ramzan-Abdul / Zaman, Ali / Aziz, Imran / Amanullah / Amin, Adnan

    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

    2021  Volume 41, Issue 3, Page(s) 376–380

    Abstract: Objective: To investigate the inhibitive efficacy of Nymphoides Indica (L.) Kuntze rhizome extract on α-glucosidase and on cross-link formation of advanced glycation end products (AGEs).: Methods: The plant extracts were prepared by cold maceration ... ...

    Abstract Objective: To investigate the inhibitive efficacy of Nymphoides Indica (L.) Kuntze rhizome extract on α-glucosidase and on cross-link formation of advanced glycation end products (AGEs).
    Methods: The plant extracts were prepared by cold maceration and fractionated in solvents of diverse polarity. The in vitro α-glucosidase inhibition assay, fluorescence spectrometry and SDS-PAGE analysis was performed for antiglycation assays.
    Results: During α-glucosidase inhibition assay significant inhibition by chloroform (0.43 mg/mL) and methanol fractions (0.66 mg/mL) was noticed. During the AGEs inhibition assay, both oxidative (BSA-MGO) and non-oxidative (BSA-glucose) modes were employed. The inhibition of AGEs by total extract was considered moderate (IC50 0.10 mg/mL) as a result of non-oxidative mode, whereas in case of oxidative mode (BASA-MGO) no activity was recorded. Among fractions the methanolic fraction presented significant results both in oxidative (IC50 0.01 mg/mL) and non-oxidative modes (IC50 0.3 mg/mL). Likewise the ethyl acetate fraction was more active in non-oxidative mode (IC50 0.04 mg/mL) compared to oxidative mode (IC50 0.32 mg/mL). During assay for inhibition of cross-link formation, the chloroform fraction significantly inhibited cross-link formation in a dose dependent mode.
    Conclusion: It was finally concluded that N. Indica rhizome extract possesses significant properties that inhibit α-glucosidase, and AGEs cross-link formation.
    MeSH term(s) Antioxidants ; Glycation End Products, Advanced ; Glycoside Hydrolase Inhibitors/pharmacology ; Humans ; Magnoliopsida/chemistry ; Plant Extracts/pharmacology ; Rhizome/chemistry ; alpha-Glucosidases
    Chemical Substances Antioxidants ; Glycation End Products, Advanced ; Glycoside Hydrolase Inhibitors ; Plant Extracts ; alpha-Glucosidases (EC 3.2.1.20)
    Language English
    Publishing date 2021-06-11
    Publishing country China
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603186-9
    ISSN 2589-451X ; 0254-6272 ; 0255-2922
    ISSN (online) 2589-451X ; 0254-6272
    ISSN 0255-2922
    DOI 10.19852/j.cnki.jtcm.2021.03.005
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