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  1. Book: Ultrasound of the Diaphragm and the Respiratory Muscles

    Zambon, Massimo

    2022  

    Abstract: Ultrasound is the most reliable, easily available, fast, non-invasive technique to study diaphragm function, and is an irreplaceable tool to diagnose, monitor, and follow -up critical respiratory patients. This essential guide analyses every aspect of ... ...

    Author's details Dr Massimo Zambon is a skilled Anesthesiologist and Critical Care specialist, Head of Department of Anesthesia and Intensive Care of the Uboldo Hospital in Cernusco sul Naviglio – Milan. He holds wide expertise in intensive care medicine, mainly focusing in the application of ultrasound in critically ill patients. In the last decade, he has started to perform ultrasound of the diaphragm on critically ill patients, an innovative and non-invasive tool that allows to assess respiratory muscle function. He has published more than 20 papers in critical care indexed journals, mostly focused on ultrasound, and a number of abstracts and book chapters
    Abstract Ultrasound is the most reliable, easily available, fast, non-invasive technique to study diaphragm function, and is an irreplaceable tool to diagnose, monitor, and follow -up critical respiratory patients. This essential guide analyses every aspect of ultrasound of the diaphragm and respiratory muscles, a reliable assessment whose function is vital to delivering the most suitable treatment. Ultrasound of the Diaphragm and the Respiratory Muscles also provides insight to diagnosing diaphragmat...
    Keywords Diaphragm ultrasound ; diaphragmatic paralysis ; diaphragmatic dysfunction ; diaphragm excursion ; monitoring mechanical ventilation ; weaning
    Language English
    Size 168 p.
    Edition 1
    Publisher Taylor & Francis Ltd
    Document type Book
    Note PDA Manuell_13
    Format 156 x 234
    ISBN 9780367652777 ; 0367652773
    Database PDA

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  2. Article ; Online: The End of B/Yamagata Influenza Transmission - Transitioning from Quadrivalent Vaccines.

    Monto, Arnold S / Zambon, Maria / Weir, Jerry P

    The New England journal of medicine

    2024  Volume 390, Issue 14, Page(s) 1256–1258

    MeSH term(s) Humans ; Antibodies, Viral ; Hemagglutination Inhibition Tests ; Influenza A Virus, H3N2 Subtype ; Influenza B virus ; Influenza Vaccines/therapeutic use ; Influenza, Human/prevention & control ; Influenza, Human/transmission ; Influenza, Human/virology ; Vaccines, Combined ; Vaccines, Inactivated
    Chemical Substances Antibodies, Viral ; Influenza Vaccines ; Vaccines, Combined ; Vaccines, Inactivated
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMp2314801
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  3. Article ; Online: Zika virus, the new kid on the block.

    Zambon, Maria

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

    2016  Volume 21, Issue 23

    MeSH term(s) Disease Outbreaks/prevention & control ; Disease Outbreaks/statistics & numerical data ; Global Health ; Humans ; Mass Vaccination/trends ; Prevalence ; Risk Factors ; Zika Virus Infection/epidemiology ; Zika Virus Infection/prevention & control
    Keywords covid19
    Language English
    Publishing date 2016-06-09
    Publishing country Sweden
    Document type Editorial
    ZDB-ID 1338803-4
    ISSN 1560-7917 ; 1025-496X
    ISSN (online) 1560-7917
    ISSN 1025-496X
    DOI 10.2807/1560-7917.ES.2016.21.23.30255
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  4. Article ; Online: Integrated respiratory surveillance after the COVID-19 pandemic.

    Elson, William / Zambon, Maria / de Lusignan, Simon

    Lancet (London, England)

    2022  Volume 400, Issue 10367, Page(s) 1924–1925

    MeSH term(s) Humans ; COVID-19 ; Pandemics
    Language English
    Publishing date 2022-12-03
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(22)02325-X
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  5. Article ; Online: Developments in the treatment of severe influenza: lessons from the pandemic of 2009 and new prospects for therapy.

    Zambon, Maria

    Current opinion in infectious diseases

    2014  Volume 27, Issue 6, Page(s) 560–565

    Abstract: Purpose of review: Cases of severe influenza may occur during seasonal epidemics, following sporadic zoonotic influenza A transmission from animal reservoirs or on a massive scale with the unpredictable emergence of a new pandemic influenza strain. ... ...

    Abstract Purpose of review: Cases of severe influenza may occur during seasonal epidemics, following sporadic zoonotic influenza A transmission from animal reservoirs or on a massive scale with the unpredictable emergence of a new pandemic influenza strain. Clinical experience identifies unmet medical need for additional therapies for influenza, in particular to treat severely unwell adults and children. During and following the pandemic of 2009, a wealth of data from hospitalized cases of influenza from many different countries accumulated and are now starting to emerge. Observational clinical data provide information about the efficacy of existing antiviral drugs in severely ill patients. The development pipeline for new therapies contains several promising agents which are focussed on a range of viral targets, and opens the possibility of combination antiviral therapy for the first time, which may be especially useful in clinically challenging cases. Advances in immunological methods and recombinant protein engineering support the potential for use of immunomodulating therapies as adjuncts in treatment of severe influenza.
    Recent findings: The main themes are the importance of treating severe influenza early, considering multiple therapy options and the relevance of observational clinical data to treatment of severely ill and risk groups.
    Summary: Clinicians, who may have only seen the media headlines following discussion of reviews which deal with randomized controlled trials of neuraminidase inhibitor drug use in mild uncomplicated influenza in the community, may be hesitant to prescribe these drugs. Observational data arising from treatment of severely ill individuals support use of these drugs early in illness and show improvement in outcomes associated with drug use.
    MeSH term(s) Animals ; Antiviral Agents/adverse effects ; Antiviral Agents/therapeutic use ; Birds ; Enzyme Inhibitors/adverse effects ; Enzyme Inhibitors/therapeutic use ; Humans ; Immunologic Factors/therapeutic use ; Influenza in Birds/epidemiology ; Influenza in Birds/immunology ; Influenza in Birds/prevention & control ; Influenza, Human/drug therapy ; Influenza, Human/epidemiology ; Influenza, Human/immunology ; Neuraminidase/antagonists & inhibitors ; Oseltamivir/adverse effects ; Oseltamivir/therapeutic use ; Pandemics ; Population Surveillance ; Public Health ; Randomized Controlled Trials as Topic ; Zanamivir/adverse effects ; Zanamivir/therapeutic use
    Chemical Substances Antiviral Agents ; Enzyme Inhibitors ; Immunologic Factors ; Oseltamivir (20O93L6F9H) ; Neuraminidase (EC 3.2.1.18) ; Zanamivir (L6O3XI777I)
    Keywords covid19
    Language English
    Publishing date 2014-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645085-4
    ISSN 1473-6527 ; 1535-3877 ; 0951-7375 ; 1355-834X
    ISSN (online) 1473-6527 ; 1535-3877
    ISSN 0951-7375 ; 1355-834X
    DOI 10.1097/QCO.0000000000000113
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  6. Article: Blue Sclerae and Differential Diagnosis in Chest Pain: A Case Report.

    Miantti Ghellere Bonfim, Luana C / S Guerini, Isadora / G Zambon, Marjorie / A Lopes, Marcela

    Cureus

    2023  Volume 15, Issue 8, Page(s) e43542

    Abstract: Osteogenesis imperfecta (OI) constitutes a complex connective tissue disorder extending beyond its hallmark bone fragility. This case report explores the intricate diagnostic journey involving an elderly patient with acute chest pain, blue sclerae, and ... ...

    Abstract Osteogenesis imperfecta (OI) constitutes a complex connective tissue disorder extending beyond its hallmark bone fragility. This case report explores the intricate diagnostic journey involving an elderly patient with acute chest pain, blue sclerae, and multiple fractures. Despite a thorough cardiac evaluation yielding normal results, the complex medical history and phenotypic markers directed attention toward musculoskeletal factors, underlining the importance of comprehensive diagnostic approaches in hereditary conditions like OI.
    Language English
    Publishing date 2023-08-15
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.43542
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  7. Article: Investigating Blood Donors With Postdonation Respiratory Tract Symptoms During the Wild-Type, Delta, and Omicron Waves of the Coronavirus Disease 2019 Pandemic in England.

    Gates, Shannah / Ijaz, Samreen / Baklan, Hatice / Washington, Charlotte / Brailsford, Su / Zambon, Maria / Harvala, Heli

    Open forum infectious diseases

    2023  Volume 10, Issue 10, Page(s) ofad499

    Abstract: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been shown to be detectable in blood from infected individuals. Though RNAemia frequencies are typically low, the presence of potentially infectious virus potentially ...

    Abstract Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been shown to be detectable in blood from infected individuals. Though RNAemia frequencies are typically low, the presence of potentially infectious virus potentially poses a transmission risk during blood transfusion.
    Methods: Archived plasma samples were collected from blood donors who later reported possible SARS-CoV-2 infection with the wild-type strain, Delta variant, or Omicron variant. This was based on either symptom onset or a positive test within 2 weeks from their donation. Donations were tested for SARS-CoV-2 RNA, and information on symptoms and testing results were gathered during postdonation interview.
    Results: Of 518 archived plasma samples tested, 19 (3.7%) were found to have detectable levels of SARS-CoV-2 RNA. SARS-CoV-2 RNA was detected in donors who donated during the Delta (10/141 [7.1%]) and Omicron (9/162 [5.6%]) waves. SARS-CoV-2 RNA was not detected in donors who donated during the wild-type wave (0/215). Seventeen of 19 RNAemic donors reported symptom onset or a positive test within 2 days of donating. SARS-CoV-2 RNA was detected in asymptomatic or presymptomatic blood donors.
    Conclusions: Despite RNAemia being correlated with SARS-CoV-2 disease severity, RNAemia was detected in asymptomatic or presymptomatic blood donors.
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofad499
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  8. Article: Influenza and other emerging respiratory viruses.

    Zambon, Maria

    Medicine (Abingdon, England : UK ed.)

    2013  Volume 42, Issue 1, Page(s) 45–51

    Abstract: Acute lower respiratory tract infections (LRTIs) are a major worldwide health problem, particularly in childhood. About 30-50% of acute LRTIs are viral in origin with influenza A infection a key cause of explosive community outbreaks. Many different ... ...

    Abstract Acute lower respiratory tract infections (LRTIs) are a major worldwide health problem, particularly in childhood. About 30-50% of acute LRTIs are viral in origin with influenza A infection a key cause of explosive community outbreaks. Many different influenza A viruses occur naturally in animal reservoirs and present a constant threat of zoonotic infections and global pandemics. Since 2009, when pandemic (H1N1) influenza A emerged from a swine origin, there have been a number of different zoonotic influenza A transmissions into the human population, including H1N1 and H3N2 variant viruses in North America and H7N9 viruses in China. The segmented nature of the influenza A virus genome and the circulation of these viruses in wild bird, domestic poultry and mammalian reservoirs presents a continuous opportunity for reassortment of viral genes and the emergence of a novel pandemic virus. Constant vigilance is required. The emergence of severe acute respiratory syndrome in 2003 and Middle East respiratory syndrome coronavirus in 2012, highlights the fact that other serious respiratory viral infections in humans may originate in animals. Enhanced awareness of the potential for serious human respiratory disease in association with travel, or animal exposure, should form part of clinical assessment. Rapid developments in genomic technology improve the ability to diagnose previously undetected pathogens. Preventative measures for influenza include annual vaccination and treatment with antiviral drugs such as neuraminidase inhibitors, oseltamivir and zanamivir. Subtype-dependent resistance to antivirals can develop and should be closely monitored.
    Keywords covid19
    Language English
    Publishing date 2013-12-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1238899-3
    ISSN 1357-3039
    ISSN 1357-3039
    DOI 10.1016/j.mpmed.2013.10.017
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  9. Article ; Online: Influenza imprinting in childhood and the influence on vaccine response later in life.

    Kelvin, Alyson A / Zambon, Maria

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

    2019  Volume 24, Issue 48

    MeSH term(s) Antibodies, Viral/immunology ; Child ; Female ; Humans ; Immunologic Memory ; Influenza A Virus, H1N1 Subtype/immunology ; Influenza A Virus, H3N2 Subtype/immunology ; Influenza Vaccines/administration & dosage ; Influenza Vaccines/immunology ; Influenza, Human/epidemiology ; Influenza, Human/prevention & control ; Influenza, Human/virology ; Male
    Chemical Substances Antibodies, Viral ; Influenza Vaccines
    Language English
    Publishing date 2019-12-03
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 1338803-4
    ISSN 1560-7917 ; 1025-496X
    ISSN (online) 1560-7917
    ISSN 1025-496X
    DOI 10.2807/1560-7917.ES.2019.24.48.1900720
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  10. Article ; Online: Polio eradication: next steps and future challenges.

    Zambon, Maria / Martin, Javier

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

    2018  Volume 23, Issue 47

    MeSH term(s) Disease Eradication/methods ; Humans ; Poliomyelitis/prevention & control ; Poliomyelitis/virology ; Poliovirus/immunology ; Poliovirus Vaccine, Inactivated/administration & dosage ; Poliovirus Vaccine, Inactivated/immunology ; Poliovirus Vaccine, Oral/administration & dosage ; Poliovirus Vaccine, Oral/immunology ; Public Health
    Chemical Substances Poliovirus Vaccine, Inactivated ; Poliovirus Vaccine, Oral
    Language English
    Publishing date 2018-11-28
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 1338803-4
    ISSN 1560-7917 ; 1025-496X
    ISSN (online) 1560-7917
    ISSN 1025-496X
    DOI 10.2807/1560-7917.ES.2018.23.47.1800625
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