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  1. Article ; Online: ASO Author Reflections: Low Case-Load and Lack of Centralization have Negative Impact on Uterine Sarcoma Outcomes.

    Gorostidi, Mikel / Zapardiel, Ignacio

    Annals of surgical oncology

    2023  Volume 30, Issue 12, Page(s) 7663–7664

    MeSH term(s) Humans ; Pelvic Neoplasms ; Sarcoma/therapy ; Soft Tissue Neoplasms
    Language English
    Publishing date 2023-07-15
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-13871-z
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    Zs.A 4042: Show issues Location:
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  2. Article ; Online: Current limits of conservative treatment in ovarian cancer.

    Gracia, Myriam / Alonso-Espías, María / Zapardiel, Ignacio

    Current opinion in oncology

    2023  Volume 35, Issue 5, Page(s) 389–393

    Abstract: Purpose of review: Fertility-sparing surgery in ovarian cancer is an increasing need in gynecology-oncology clinical practice because of the frequent childbearing delay in developed countries. As the evidence in literature is based on observational ... ...

    Abstract Purpose of review: Fertility-sparing surgery in ovarian cancer is an increasing need in gynecology-oncology clinical practice because of the frequent childbearing delay in developed countries. As the evidence in literature is based on observational studies, this review focuses on summarizing the most recent and relevant evidence for the conservative management of young patients with ovarian cancer.
    Recent findings: Staging surgery is mandatory in epithelial ovarian tumors. In sex cord-stromal tumors, fertility-sparing surgery is only recommended in FIGO stage IA. Due to its good prognosis, conservative treatment is possible in some cases of advanced disease of germ cell tumors and borderline tumors. Cystectomy is a reasonable option in serous borderline tumors but is not recommended in other tumor subtypes. Successful conception rates after fertility-sparing surgery ranges from 30 to 60%.
    Summary: Fertility-sparing surgery is a well tolerated option in young women with early-stage ovarian cancer with acceptable reproductive outcomes.
    MeSH term(s) Humans ; Female ; Conservative Treatment ; Ovariectomy ; Ovarian Neoplasms/surgery ; Fertility ; Fertility Preservation ; Neoplasm Staging ; Neoplasm Recurrence, Local/pathology
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1049384-0
    ISSN 1531-703X ; 1040-8746
    ISSN (online) 1531-703X
    ISSN 1040-8746
    DOI 10.1097/CCO.0000000000000970
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    Zs.A 3046: Show issues Location:
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  3. Article ; Online: Role of fluorescence imaging for intraoperative intestinal assessment in gynecological surgery: a systematic review.

    Spagnolo, Emanuela / Zapardiel, Ignacio / Gorostidi, Mikel

    Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy

    2022  Volume 31, Issue 7, Page(s) 992–999

    Abstract: Background: Our aim was to review the current knowledge of the role of fluorescence imaging for intraoperative intestinal assessment in gynecological surgery.: Material and methods: A computer-based systematic review was performed from 2000 to 2020. ... ...

    Abstract Background: Our aim was to review the current knowledge of the role of fluorescence imaging for intraoperative intestinal assessment in gynecological surgery.
    Material and methods: A computer-based systematic review was performed from 2000 to 2020. All articles describing the use of indocyanine green (ICG) applied to bowel assessments in gynecology or endometriosis surgery were considered for review.
    Results: ICG is an effective tool for assessing bowel vascularization, potentially preventing anastomotic leakage and recto-vaginal fistula and can therefore be useful for endometriosis surgery or bowel assessment in gynecological oncology procedures. Real-time characterization of the hypovascular pattern of endometriotic nodules has been associated with a larger nodule size and lower microvessel density, helping surgeons choose the best transecting line and the most appropriate technique. ICG angiography allows for a laparoscopic and intrarectal bowel assessment, which can act as a double check of bowel perfusion, enabling the assessment of mucosa vascularization. ICG fluorescence can guide intraoperative decision-making after intestinal anastomosis, discoid resection, and rectal shaving, preventing anastomotic leakage and postoperative recto-vaginal fistula in low anterior resections.
    Conclusions: ICG angiography provides a better intestinal assessment. Larger, prospective, randomized controlled studies are needed to validate the technique and confirm these encouraging results.
    MeSH term(s) Anastomosis, Surgical/methods ; Anastomotic Leak/prevention & control ; Anastomotic Leak/surgery ; Endometriosis/surgery ; Female ; Gynecologic Surgical Procedures ; Humans ; Indocyanine Green ; Laparoscopy/methods ; Optical Imaging/methods ; Prospective Studies ; Vaginal Fistula/surgery
    Chemical Substances Indocyanine Green (IX6J1063HV)
    Language English
    Publishing date 2022-04-20
    Publishing country England
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 1317160-4
    ISSN 1365-2931 ; 1364-5706
    ISSN (online) 1365-2931
    ISSN 1364-5706
    DOI 10.1080/13645706.2022.2064715
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    Zs.A 3467: Show issues Location:
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  4. Article ; Online: Author's response to letter to editor on VULCAN study.

    Zapardiel, Ignacio / Coronado, Pluvio J

    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

    2020  Volume 31, Issue 1, Page(s) 158

    Language English
    Publishing date 2020-11-13
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1070385-8
    ISSN 1525-1438 ; 1048-891X
    ISSN (online) 1525-1438
    ISSN 1048-891X
    DOI 10.1136/ijgc-2020-002190
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    Zs.A 3198: Show issues Location:
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  5. Article ; Online: ASO Author Reflections: Fluorescence-Guided Surgery in Gynecology Becomes a Standard.

    Gorostidi, Mikel / Zapardiel, Ignacio

    Annals of surgical oncology

    2020  Volume 28, Issue 6, Page(s) 3279–3280

    MeSH term(s) Fluorescence ; Gynecology ; Humans
    Language English
    Publishing date 2020-10-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-020-09231-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4042: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  6. Article ; Online: Avascular spaces in radical hysterectomy.

    Zapardiel, Ignacio / Ceccaroni, Marcello / Minig, Lucas / Halaska, Michael J / Fujii, Shingo

    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

    2023  Volume 33, Issue 2, Page(s) 285–292

    Abstract: The most common cancer in women worldwide is cervical cancer. For early-stage disease the standard treatment is radical hysterectomy. One of the main issues faced by surgeons performing a radical hysterectomy is the wide variation in the terminology used ...

    Abstract The most common cancer in women worldwide is cervical cancer. For early-stage disease the standard treatment is radical hysterectomy. One of the main issues faced by surgeons performing a radical hysterectomy is the wide variation in the terminology used to define the procedure and the nomenclature used to describe the anatomical spaces critical to the success of the surgery. The aim of this review was to synthesize currently used anatomical landmarks with relation to surgical avascular spaces for the performance of radical hysterectomy.A computer-based comprehensive review of the MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, Embase, and SciSearch databases, as well as National Comprehensive Cancer Network and European Society of Gynaecological Oncology guidelines, was performed. With all relevant data collected, and previous anatomical studies during surgeries and on cadavers performed by authors, a manuscript of the definition of avascular spaces, methods of dissection, and anatomical limits was prepared.Avascular pelvic spaces developed during radical hysterectomy, such as the paravesical, pararectal, ureter tunnel, and paravaginal, were considered and included in the manuscript. A clear definition of avascular spaces may aid a better understanding of the anatomical aspects of the radical hysterectomy. It could improve surgeon knowledge of the structures that need to be preserved and those that need to be resected during a radical hysterectomy. Additionally, the detailed exposure of anatomical boundaries will facilitate the appropriate tailored radicality depending on the risk factors of the disease. Moreover, knowledge of these spaces could make pelvic surgery safer and easier for other types of gynecological and non-gynecological procedures.
    MeSH term(s) Female ; Humans ; Neoplasm Staging ; Hysterectomy/methods ; Uterine Cervical Neoplasms/pathology ; Pelvis/pathology ; Dissection
    Language English
    Publishing date 2023-02-06
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1070385-8
    ISSN 1525-1438 ; 1048-891X
    ISSN (online) 1525-1438
    ISSN 1048-891X
    DOI 10.1136/ijgc-2022-004071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3198: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article: ESGO/ESHRE/ESGE Guidelines for the fertility-sparing treatment of patients with endometrial carcinoma.

    Rodolakis, A / Scambia, G / Planchamp, F / Acien, M / Di Spiezio Sardo, A / Farrugia, M / Grynberg, M / Pakiž, M / Pavlakis, K / Vermeulen, N / Zannoni, G / Zapardiel, I / Tryde Macklon, K L

    Facts, views & vision in ObGyn

    2023  Volume 15, Issue 1, Page(s) 3–23

    Abstract: Background: The standard surgical treatment of endometrial carcinoma (EC) consisting of total hysterectomy with bilateral salpingo-oophorectomy drastically affects the quality of life of patients and creates a challenge for clinicians. Recent evidence- ... ...

    Abstract Background: The standard surgical treatment of endometrial carcinoma (EC) consisting of total hysterectomy with bilateral salpingo-oophorectomy drastically affects the quality of life of patients and creates a challenge for clinicians. Recent evidence-based guidelines of the European Society of Gynaecological Oncology (ESGO), the European SocieTy for Radiotherapy & Oncology (ESTRO) and the European Society of Pathology (ESP) provide comprehensive guidelines on all relevant issues of diagnosis and treatment in EC in a multidisciplinary setting. While also addressing work-up for fertility preservation treatments and the management and follow-up for fertility preservation, it was considered relevant to further extend the guidance on fertility sparing treatment.
    Objectives: To define recommendations for fertility-sparing treatment of patients with endometrial carcinoma.
    Materials and methods: ESGO/ESHRE/ESGE nominated an international multidisciplinary development group consisting of practicing clinicians and researchers who have demonstrated leadership and expertise in the care and research of EC (11 experts across Europe). To ensure that the guidelines are evidence-based, the literature published since 2016, identified from a systematic search was reviewed and critically appraised. In the absence of any clear scientific evidence, judgment was based on the professional experience and consensus of the development group. The guidelines are thus based on the best available evidence and expert agreement. Prior to publication, the guidelines were reviewed by 95 independent international practitioners in cancer care delivery and patient representatives.
    Results: The multidisciplinary development group formulated 48 recommendations for fertility-sparing treatment of patients with endometrial carcinoma in four sections: patient selection, tumour clinicopathological characteristics, treatment and special issues.
    Conclusions: These recommendations provide guidance to professionals caring for women with endometrial carcinoma, including but not limited to professionals in the field of gynaecological oncology, onco-fertility, reproductive surgery, endoscopy, conservative surgery, and histopathology, and will help towards a holistic and multidisciplinary approach for this challenging clinical scenario.
    What is new?: A collaboration was set up between the ESGO, ESHRE and ESGE, aiming to develop clinically relevant and evidence-based guidelines focusing on key aspects of fertility-sparing treatment in order to improve the quality of care for women with endometrial carcinoma across Europe and worldwide.
    Language English
    Publishing date 2023-04-03
    Publishing country Belgium
    Document type Journal Article
    ZDB-ID 2701574-9
    ISSN 2032-0418 ; 2684-4230
    ISSN 2032-0418 ; 2684-4230
    DOI 10.52054/FVVO.15.1.065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: ESGO/ESHRE/ESGE Guidelines for the fertility-sparing treatment of patients with endometrial carcinoma.

    Rodolakis, A / Scambia, G / Planchamp, F / Acien, M / Di Spiezio Sardo, A / Farrugia, M / Grynberg, M / Pakiž, M / Pavlakis, K / Vermeulen, N / Zannoni, G / Zapardiel, I / Tryde Macklon, K L

    Facts, views & vision in ObGyn

    2023  Volume 15, Issue 1

    Abstract: Background: The standard surgical treatment of endometrial carcinoma (EC) consisting of total hysterectomy with bilateral salpingo-oophorectomy drastically affects the quality of life of patients and creates a challenge for clinicians. Recent evidence- ... ...

    Abstract Background: The standard surgical treatment of endometrial carcinoma (EC) consisting of total hysterectomy with bilateral salpingo-oophorectomy drastically affects the quality of life of patients and creates a challenge for clinicians. Recent evidence-based guidelines of the European Society of Gynaecological Oncology (ESGO), the European SocieTy for Radiotherapy & Oncology (ESTRO) and the European Society of Pathology (ESP) provide comprehensive guidelines on all relevant issues of diagnosis and treatment in EC in a multidisciplinary setting. While also addressing work-up for fertility preservation treatments and the management and follow-up for fertility preservation, it was considered relevant to further extend the guidance on fertility sparing treatment.
    Objectives: To define recommendations for fertility-sparing treatment of patients with endometrial carcinoma.
    Materials and methods: ESGO/ESHRE/ESGE nominated an international multidisciplinary development group consisting of practicing clinicians and researchers who have demonstrated leadership and expertise in the care and research of EC (11 experts across Europe). To ensure that the guidelines are evidence-based, the literature published since 2016, identified from a systematic search was reviewed and critically appraised. In the absence of any clear scientific evidence, judgment was based on the professional experience and consensus of the development group. The guidelines are thus based on the best available evidence and expert agreement. Prior to publication, the guidelines were reviewed by 95 independent international practitioners in cancer care delivery and patient representatives.
    Results: The multidisciplinary development group formulated 48 recommendations for fertility-sparing treatment of patients with endometrial carcinoma in four sections: patient selection, tumour clinicopathological characteristics, treatment and special issues.
    Conclusions: These recommendations provide guidance to professionals caring for women with endometrial carcinoma, including but not limited to professionals in the field of gynaecological oncology, onco-fertility, reproductive surgery, endoscopy, conservative surgery, and histopathology, and will help towards a holistic and multidisciplinary approach for this challenging clinical scenario. What is new? A collaboration was set up between the ESGO, ESHRE and ESGE, aiming to develop clinically relevant and evidence-based guidelines focusing on key aspects of fertility-sparing treatment in order to improve the quality of care for women with endometrial carcinoma across Europe and worldwide.
    Language English
    Publishing date 2023-02-06
    Publishing country Belgium
    Document type Journal Article
    ZDB-ID 2701574-9
    ISSN 2032-0418 ; 2684-4230
    ISSN 2032-0418 ; 2684-4230
    DOI 10.52054/FVVO.14.4.054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Bowel and ureteral assessment by indocyanine green real-time visualization during deep infiltrating endometriosis surgery - a video vignette.

    Spagnolo, E / Hernández, A / Pascual, I / Cabanes, M / López, A / Zapardiel, I

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2020  Volume 22, Issue 10, Page(s) 1464–1465

    MeSH term(s) Endometriosis/diagnostic imaging ; Endometriosis/surgery ; Female ; Humans ; Indocyanine Green ; Laparoscopy ; Rectal Diseases/surgery ; Ureter
    Chemical Substances Indocyanine Green (IX6J1063HV)
    Keywords covid19
    Language English
    Publishing date 2020-05-25
    Publishing country England
    Document type Letter ; Video-Audio Media
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15093
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    Zs.A 5799: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  10. Article ; Online: Adapting Radicality in Early Cervical Cancer When Quality of Life Becomes a Prominent Issue.

    Zapardiel, Ignacio / Gracia, Myriam / Rychlik, Agnieszka / Querleu, Denis

    Annals of surgical oncology

    2020  Volume 28, Issue 6, Page(s) 3429–3430

    MeSH term(s) Female ; Humans ; Hysterectomy ; Quality of Life ; Uterine Cervical Neoplasms/surgery
    Language English
    Publishing date 2020-10-14
    Publishing country United States
    Document type Letter
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-020-09193-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4042: Show issues Location:
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