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  1. Article ; Online: An eco-friendly chitosan/cellulose acetate hybrid nanostructure containing Ziziphora clinopodioides essential oils for active food packaging applications

    Nazari, Maryam / Majdi, Hasan / Gholizadeh, Pourya / Kafil, Hossein Samadi / Hamishehkar, Hamed / Zarchi, Ali Akbar Karimi / Khoddami, Ali

    International Journal of Biological Macromolecules. 2023 Apr., v. 235 p.123885-

    2023  

    Abstract: This work presents the fabrication and characterization of a hybrid nanostructure, Ziziphora clinopodioides essential oils (ZEO)-loaded chitosan nanoparticles (CSNPs-ZEO) embedded into cellulose acetate (CA) nanofibers (CA-CSNPs-ZEO). The CSNPs-ZEO were ... ...

    Abstract This work presents the fabrication and characterization of a hybrid nanostructure, Ziziphora clinopodioides essential oils (ZEO)-loaded chitosan nanoparticles (CSNPs-ZEO) embedded into cellulose acetate (CA) nanofibers (CA-CSNPs-ZEO). The CSNPs-ZEO were first synthesized through the ionic gelation method. Then, through simultaneous electrospraying and electrospinning processes, the nanoparticles were embedded in the CA nanofibers. The morphological and physicochemical characteristics of the prepared nanostructures were evaluated using different methods, including scanning electron microscopy (SEM), water vapor permeability (WVP), moisture content (MC), mechanical testing, differential scanning calorimetry (DSC), and release profile studies. The antibacterial activity of the nanostructures was explored on raw beef as a food model during 12 days of storage at 4 °C. The obtained results indicated the successful synthesis of CSNPs-ZEO nanoparticles with an average size of 267 ± 6 nm and their incorporation into the nanofibers matrix. Moreover, the CA-CSNPs-ZEO nanostructure showed a lower water vapor barrier and higher tensile strength compared with ZEO-loaded CA (CA-ZEO) nanofiber. The CA-CSNPs-ZEO nanostructure also exhibited strong antibacterial activity, which effectively extended the shelf-life of raw beef. The results demonstrated a strong potential for innovative hybrid nanostructures in active packaging to maintain the quality of perishable food products.
    Keywords Ziziphora clinopodioides ; antibacterial properties ; beef ; calorimetry ; cellulose acetate ; chitosan ; electron microscopy ; electrospraying ; gelation ; model food systems ; nanofibers ; nanoparticles ; perishable foods ; permeability ; shelf life ; tensile strength ; water content ; water vapor ; Electrospinning ; Cellulose acetate nanofiber ; Chitosan nanoparticles ; Essential oils
    Language English
    Dates of publication 2023-04
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.123885
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: An eco-friendly chitosan/cellulose acetate hybrid nanostructure containing Ziziphora clinopodioides essential oils for active food packaging applications.

    Nazari, Maryam / Majdi, Hasan / Gholizadeh, Pourya / Kafil, Hossein Samadi / Hamishehkar, Hamed / Zarchi, Ali Akbar Karimi / Khoddami, Ali

    International journal of biological macromolecules

    2023  Volume 235, Page(s) 123885

    Abstract: This work presents the fabrication and characterization of a hybrid nanostructure, Ziziphora clinopodioides essential oils (ZEO)-loaded chitosan nanoparticles (CSNPs-ZEO) embedded into cellulose acetate (CA) nanofibers (CA-CSNPs-ZEO). The CSNPs-ZEO were ... ...

    Abstract This work presents the fabrication and characterization of a hybrid nanostructure, Ziziphora clinopodioides essential oils (ZEO)-loaded chitosan nanoparticles (CSNPs-ZEO) embedded into cellulose acetate (CA) nanofibers (CA-CSNPs-ZEO). The CSNPs-ZEO were first synthesized through the ionic gelation method. Then, through simultaneous electrospraying and electrospinning processes, the nanoparticles were embedded in the CA nanofibers. The morphological and physicochemical characteristics of the prepared nanostructures were evaluated using different methods, including scanning electron microscopy (SEM), water vapor permeability (WVP), moisture content (MC), mechanical testing, differential scanning calorimetry (DSC), and release profile studies. The antibacterial activity of the nanostructures was explored on raw beef as a food model during 12 days of storage at 4 °C. The obtained results indicated the successful synthesis of CSNPs-ZEO nanoparticles with an average size of 267 ± 6 nm and their incorporation into the nanofibers matrix. Moreover, the CA-CSNPs-ZEO nanostructure showed a lower water vapor barrier and higher tensile strength compared with ZEO-loaded CA (CA-ZEO) nanofiber. The CA-CSNPs-ZEO nanostructure also exhibited strong antibacterial activity, which effectively extended the shelf-life of raw beef. The results demonstrated a strong potential for innovative hybrid nanostructures in active packaging to maintain the quality of perishable food products.
    MeSH term(s) Animals ; Cattle ; Food Packaging/methods ; Chitosan/chemistry ; Oils, Volatile/chemistry ; Steam ; Lamiaceae/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Nanoparticles/chemistry ; Nanofibers
    Chemical Substances acetylcellulose (3J2P07GVB6) ; Chitosan (9012-76-4) ; Oils, Volatile ; Steam ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-03-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.123885
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Osteogenic differentiation of hMSCs on semi-interpenetrating polymer networks of polyurethane/poly(2‑hydroxyethyl methacrylate)/cellulose nanowhisker scaffolds.

    Shahrousvand, Mohsen / Ghollasi, Marzieh / Zarchi, Ali Akbar Karimi / Salimi, Ali

    International journal of biological macromolecules

    2019  Volume 138, Page(s) 262–271

    Abstract: Poly (2‑hydroxyethyl methacrylate) (PHEMA) was crosslinked in the presence of biocompatible and biodegradable poly(caprolactone) (PCL) based polyurethanes (PUs) and cellulose nanowhiskers (CNWs). The CNWs were obtained from wastepaper. In order to ... ...

    Abstract Poly (2‑hydroxyethyl methacrylate) (PHEMA) was crosslinked in the presence of biocompatible and biodegradable poly(caprolactone) (PCL) based polyurethanes (PUs) and cellulose nanowhiskers (CNWs). The CNWs were obtained from wastepaper. In order to crosslink PHEMA (10 wt%), a novel acrylic-urethane cross-linker was produced by a condensation reaction of PHEMA and hexamethylene diisocyanate (HDI). The PU-PHEMA-CNWs scaffolds were prepared by solvent casting/particulate leaching method in different weight percentages of CNWs (i.e., 0, 0.1, 0.5, and 1 wt%). The structural, mechanical, and in vitro biological properties of bio-nanocomposites were evaluated via FTIR, SEM, tensile, and MTT assay. The tensile strength of PU-PHEMA-0, PU-PHEMA-0.1, PU-PHEMA-0.5, and PU-PHEMA-1 were 76.2, 95.8, 98.1, and 89.8 kPa, respectively. Incorporation of CNWs also resulted in improved cell proliferation on PU-PHEMA-CNWs scaffolds. The bone marrow derived human mesenchymal stem cells (hMSCs) were seeded on the prepared porous scaffolds and incubated in osteogenic medium. Based on the results including calcium content assay, alkaline phosphatase assay, and mineralization staining, PU-PHEMA-CNW scaffolds were introduced as a suitable election for imitating the behavior of cellular niche. Bone mineralization and osteogenesis differentiation of hMSCs on PU-PHEMA-CNW scaffolds were significantly more than control after 14 days.
    MeSH term(s) Adsorption ; Alkaline Phosphatase/metabolism ; Calcium/metabolism ; Cell Differentiation/drug effects ; Cellulose/chemistry ; Humans ; Hydrolysis ; Mechanical Phenomena ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/drug effects ; Minerals/metabolism ; Osteogenesis/drug effects ; Polyhydroxyethyl Methacrylate/chemistry ; Polyurethanes/chemistry ; Polyurethanes/pharmacology ; Water/chemistry ; Wettability
    Chemical Substances Minerals ; Polyurethanes ; Water (059QF0KO0R) ; Polyhydroxyethyl Methacrylate (25249-16-5) ; Cellulose (9004-34-6) ; Alkaline Phosphatase (EC 3.1.3.1) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2019-07-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2019.07.080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Osteogenic differentiation of hMSCs on semi-interpenetrating polymer networks of polyurethane/poly(2‐hydroxyethyl methacrylate)/cellulose nanowhisker scaffolds

    Shahrousvand, Mohsen / Ghollasi, Marzieh / Zarchi, Ali Akbar Karimi / Salimi, Ali

    International journal of biological macromolecules. 2019 Oct. 01, v. 138

    2019  

    Abstract: Poly (2‐hydroxyethyl methacrylate) (PHEMA) was crosslinked in the presence of biocompatible and biodegradable poly(caprolactone) (PCL) based polyurethanes (PUs) and cellulose nanowhiskers (CNWs). The CNWs were obtained from wastepaper. In order to ... ...

    Abstract Poly (2‐hydroxyethyl methacrylate) (PHEMA) was crosslinked in the presence of biocompatible and biodegradable poly(caprolactone) (PCL) based polyurethanes (PUs) and cellulose nanowhiskers (CNWs). The CNWs were obtained from wastepaper. In order to crosslink PHEMA (10 wt%), a novel acrylic-urethane cross-linker was produced by a condensation reaction of PHEMA and hexamethylene diisocyanate (HDI). The PU-PHEMA-CNWs scaffolds were prepared by solvent casting/particulate leaching method in different weight percentages of CNWs (i.e., 0, 0.1, 0.5, and 1 wt%). The structural, mechanical, and in vitro biological properties of bio-nanocomposites were evaluated via FTIR, SEM, tensile, and MTT assay. The tensile strength of PU-PHEMA-0, PU-PHEMA-0.1, PU-PHEMA-0.5, and PU-PHEMA-1 were 76.2, 95.8, 98.1, and 89.8 kPa, respectively. Incorporation of CNWs also resulted in improved cell proliferation on PU-PHEMA-CNWs scaffolds. The bone marrow derived human mesenchymal stem cells (hMSCs) were seeded on the prepared porous scaffolds and incubated in osteogenic medium. Based on the results including calcium content assay, alkaline phosphatase assay, and mineralization staining, PU-PHEMA-CNW scaffolds were introduced as a suitable election for imitating the behavior of cellular niche. Bone mineralization and osteogenesis differentiation of hMSCs on PU-PHEMA-CNW scaffolds were significantly more than control after 14 days.
    Keywords Fourier transform infrared spectroscopy ; alkaline phosphatase ; biodegradability ; bone marrow ; bone mineralization ; calcium ; cell proliferation ; cellulose ; condensation reactions ; crosslinking ; human cell lines ; lactones ; leaching ; mesenchymal stromal cells ; mineralization ; nanocomposites ; nanocrystals ; polyhydroxyethyl methacrylates ; polyurethanes ; scanning electron microscopy ; solvents ; staining ; tensile strength ; toxicity testing ; waste paper
    Language English
    Dates of publication 2019-1001
    Size p. 262-271.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2019.07.080
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: A survey on species and prevalence rate of bacterial agents isolated from cockroaches in three hospitals.

    Zarchi, Ali Akbar Karimi / Vatani, Hadi

    Vector borne and zoonotic diseases (Larchmont, N.Y.)

    2009  Volume 9, Issue 2, Page(s) 197–200

    Abstract: The presence of cockroaches has health implications, such as nosocomial infection, as the insects move freely from areas within and around hospitals that may harbor pathogenic organisms. The goals of the present study were to determine species of ... ...

    Abstract The presence of cockroaches has health implications, such as nosocomial infection, as the insects move freely from areas within and around hospitals that may harbor pathogenic organisms. The goals of the present study were to determine species of bacteria isolated from cockroaches found in three Tehran hospitals, and to determine distribution of potential vectors by species and sex. The study is descriptive laboratory research. A total of 305 cockroaches from three species were trapped and identified: Periplaneta americana (65.6%), Blatella germanica (12.1%), and Blatta orientalis (22.3%). From these potential vectors, 19 species of bacteria were isolated and identified. After transportation of cockroaches to the laboratory, separation of the whole-homogenized suspension of each species was carried out. Identification of the isolated bacteria was performed according to Burgey's Manual of Determinative Bacteriology, 9th Edition. The most common species of bacteria isolated from cockroaches were Escherichia coli, Streptococcus Group D, Bacillus spp., Klebsiella pneumoniae, and Proteus vulgaris. No statistical significance was found between sex and species of cockroach carrying bacteria (p > 0.05), but significance was found for sex in Citrobacter freundii, Staphylococcus aureus, and Streptococcus non-group A&B (p < 0.05).
    MeSH term(s) Animals ; Bacterial Infections/transmission ; Blattellidae/microbiology ; Cockroaches/microbiology ; Cross Infection/transmission ; Female ; Gram-Negative Facultatively Anaerobic Rods/isolation & purification ; Gram-Positive Bacteria/isolation & purification ; Hospitals ; Insect Vectors/microbiology ; Iran ; Male ; Periplaneta/microbiology ; Prevalence
    Language English
    Publishing date 2009-04
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2047199-3
    ISSN 1557-7759 ; 1530-3667
    ISSN (online) 1557-7759
    ISSN 1530-3667
    DOI 10.1089/vbz.2007.0230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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