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  1. Article ; Online: Self-Sampling for Human Papillomavirus Testing: Acceptability in a U.S. Safety Net Health System.

    Parker, Susan L / Amboree, Trisha L / Bulsara, Shaun / Daheri, Maria / Anderson, Matthew L / Hilsenbeck, Susan G / Jibaja-Weiss, Maria L / Zare, Mohammed / Schmeler, Kathleen M / Deshmukh, Ashish A / Chiao, Elizabeth Y / Scheurer, Michael E / Montealegre, Jane R

    American journal of preventive medicine

    2023  Volume 66, Issue 3, Page(s) 540–547

    Abstract: Introduction: Self-sampling for human papillomavirus testing is increasingly recognized as a strategy to expand cervical cancer screening access and utilization. Acceptability is a key determinant of uptake. This study assesses the acceptability of and ... ...

    Abstract Introduction: Self-sampling for human papillomavirus testing is increasingly recognized as a strategy to expand cervical cancer screening access and utilization. Acceptability is a key determinant of uptake. This study assesses the acceptability of and experiences with mailed self-sampling kits for human papillomavirus testing among underscreened patients in a safety net health system.
    Methods: A nested telephone survey was administered between 2021 and 2023 to a sample (n=272) of the 2,268 participants enrolled in the Prospective Evaluation of Self-Testing to Increase Screening trial. Trial participants include patients of a safety net health system aged 30-65 years who were not up to date on screening. Participants were asked about barriers to provider-performed screening. Kit users and nonusers were asked about their experiences.
    Results: Prevalent barriers to provider-performed screening included perceived discomfort of pelvic examination (69.4%), being uncomfortable with male providers (65.4%), and embarrassment (57.0%). Among participants who reported using the mailed kit (n=164), most reported good experiences (84.8%). Most reported self-sampling as more/equally convenient (89.0%), less/equally embarrassing (99.4%), and less/equally stressful (95.7%) than provider-performed screening. Among kit nonusers (n=43), reasons for not using the kit included forgetting about it (76.7%), preferring provider-performed screening (76.7%), and fearing cancer (67.4%).
    Conclusions: Prospective Evaluation of Self-Testing to Increase Screening trial participants generally had a positive experience with self-sampling for human papillomavirus testing. Increased comfort and reduced embarrassment/anxiety with self-sampling are relevant attributes because these were the most prevalent reported barriers to provider-performed screening. High acceptability suggests potentially high uptake when self-sampling for human papillomavirus testing receives regulatory approval and is available in safety net health systems.
    MeSH term(s) Female ; Humans ; Male ; Human Papillomavirus Viruses ; Uterine Cervical Neoplasms/prevention & control ; Self Care ; Early Detection of Cancer ; Papillomavirus Infections/diagnosis ; Papillomaviridae ; Mass Screening ; Patient Acceptance of Health Care ; Vaginal Smears
    Language English
    Publishing date 2023-11-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 632646-8
    ISSN 1873-2607 ; 0749-3797
    ISSN (online) 1873-2607
    ISSN 0749-3797
    DOI 10.1016/j.amepre.2023.10.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Mailed self-sample HPV testing kits to improve cervical cancer screening in a safety net health system: protocol for a hybrid effectiveness-implementation randomized controlled trial.

    Montealegre, Jane R / Anderson, Matthew L / Hilsenbeck, Susan G / Chiao, Elizabeth Y / Cantor, Scott B / Parker, Susan L / Daheri, Maria / Bulsara, Shaun / Escobar, Betsy / Deshmukh, Ashish A / Jibaja-Weiss, Maria L / Zare, Mohammed / Scheurer, Michael E

    Trials

    2020  Volume 21, Issue 1, Page(s) 872

    Abstract: Background: Almost 20% of U.S. women remain at risk for cervical cancer due to their inability or unwillingness to participate in periodic clinic-based screening. Self-sampling has been shown to be an effective strategy for screening women for high-risk ...

    Abstract Background: Almost 20% of U.S. women remain at risk for cervical cancer due to their inability or unwillingness to participate in periodic clinic-based screening. Self-sampling has been shown to be an effective strategy for screening women for high-risk human papillomavirus (HR-HPV) infection in specific contexts. However, its effectiveness among medically underserved women in safety net health systems has not been evaluated. Furthermore, it is also unclear whether implementation strategies such as patient navigation can be used to improve the success of self-sample screening programs by addressing patient-level barriers to participation.
    Methods/design: The Prospective Evaluation of Self-Testing to Increase Screening (PRESTIS) trial is a hybrid type 2 effectiveness-implementation pragmatic randomized controlled trial of mailed self-sample HPV testing. The aim is to assess the effectiveness of mailed self-sample HPV testing kits to improve cervical cancer screening participation among patients in a safety net health system who are overdue for clinic-based screening, while simultaneously assessing patient navigation as an implementation strategy. Its setting is a large, urban safety net health system that serves a predominantly racial/ethnic minority patient population. The trial targets recruitment of 2268 participants randomized to telephone recall (enhanced usual care, n = 756), telephone recall with mailed self-sample HPV testing kit (intervention, n = 756), or telephone recall with mailed self-sample HPV testing kit and patient navigation (intervention + implementation strategy, n = 756). The primary effectiveness outcome is completion of primary screening, defined as completion and return of mailed self-sample kit or completion of a clinic-based Pap test. Secondary effectiveness outcomes are predictors of screening and attendance for clinical follow-up among women with a positive screening test. Implementation outcomes are reach, acceptability, fidelity, adaptations, and cost-effectiveness.
    Discussion: Hybrid designs are needed to evaluate the clinical effectiveness of self-sample HPV testing in specific populations and settings, while incorporating and evaluating methods to optimize its real-world implementation. The current manuscript describes the rationale and design of a hybrid type 2 trial of self-sample HPV testing in a safety net health system. Trial findings are expected to provide meaningful data to inform screening strategies to ultimately realize the global goal of eliminating cervical cancer.
    Trial registration: ClinicalTrials.gov NCT03898167 . Registered on 01 April 2019.
    Trial status: Study start data: February 13, 2020. Recruitment status: Enrolling by invitation. Estimated primary completion date: February 15, 2023. Estimated study completion date: May 31, 2024. Protocol version 1.6 (February 25, 2020).
    MeSH term(s) Early Detection of Cancer ; Ethnicity ; Female ; Humans ; Mass Screening ; Minority Groups ; Papillomaviridae ; Papillomavirus Infections/diagnosis ; Prospective Studies ; Randomized Controlled Trials as Topic ; Uterine Cervical Neoplasms/diagnosis
    Language English
    Publishing date 2020-10-21
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-020-04790-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Laser Doppler measurements in two-phase flows

    Durst, Franz / Zaré, Mohammed

    (SFB 80 : TM ; 63)

    1975  

    Author's details by F. Durst and M. Zaré
    Series title SFB 80 : TM ; 63
    Language English
    Size III, 28, [20] S, 21 Ill. u. graph. Darst, 21 cm
    Publisher Sonderforschungsbereich 80, Ausbreitungs- u. Transportvorgänge in Strömungen, Univ. Karlsruhe
    Publishing place Karlsruhe
    Document type Book
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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