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  1. AU="Zarrintan, Armin"
  2. AU="Anne Schedel"
  3. AU="Youngmin Bu"
  4. AU="Edriss, Fatima"
  5. AU="Liu, Changxue"
  6. AU="Spruit, Martijn A"
  7. AU="Zhang, Dai-Gui"
  8. AU="Appelen, Diebrecht"
  9. AU="Moreira, Jânio Cordeiro"

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  1. Artikel ; Online: Outcomes of mechanical thrombectomy in octogenarians and nonagenarians patients with Acute Ischemic Stroke: A Systematic Review and Network Meta-Analysis.

    Zarrintan, Armin / Musmar, Basel / Ghozy, Sherief / Mansour, Mohamed / Kadirvel, Ramanathan / Kallmes, David F

    European journal of radiology

    2024  Band 176, Seite(n) 111506

    Abstract: Purpose: Acute ischemic stroke (AIS) imposes a major healthcare burden, with the elderly population often underrepresented in clinical trials. This systematic review and network meta-analysis aims to evaluate the safety and efficacy of mechanical ... ...

    Abstract Purpose: Acute ischemic stroke (AIS) imposes a major healthcare burden, with the elderly population often underrepresented in clinical trials. This systematic review and network meta-analysis aims to evaluate the safety and efficacy of mechanical thrombectomy (MT) among octogenarians and nonagenarians with AIS due to large vessel occlusion (LVO).
    Methods: A systematic search was conducted using PubMed, Web of Science, and Scopus databases. Outcomes of interest were modified Rankin Scale (mRS) score of 0-2, thrombolysis in cerebral infarction (TICI) score of 2b-3, 90-day mortality, and symptomatic intracerebral hemorrhage (sICH). The study followed Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines.
    Results: The analysis included 47 studies. Significantly lower rates of mRS score 0-2 were observed in nonagenarians (17.4 %) and octogenarians (21.3 %) compared to younger (40.2 %) patients (Odds Ratio (OR) = 3.30, 95 % Confidence Interval (CI):2.35-4.65 and OR = 2.47, 95 % CI: 2.07-2.94). 90-day mortality was significantly higher in nonagenarians (38.9 %) compared to octogenarians (25.4 %) and younger (14.0 %) patients (OR = 0.58, 95 % CI: 0.41-0.83 and OR = 0.31, 95 % CI: 0.21-0.44), and in octogenarians compared to younger patients (OR = 0.52, 95 % CI: 0.41-0.66). No significant differences were observed in TICI 2b-3 and sICH rates across groups.
    Conclusions: Our findings indicate that MT is a viable treatment option for AIS due to LVO among octogenarians and nonagenarians, albeit with nuanced differences. Specifically, octogenarians had lower 90-day mortality rates compared to nonagenarians. These insights support the need for individualized treatment plans for elderly patients with AIS due to LVO and highlight the importance of including this demographic in future clinical trials.
    Sprache Englisch
    Erscheinungsdatum 2024-05-13
    Erscheinungsland Ireland
    Dokumenttyp Journal Article
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2024.111506
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  2. Artikel: Prevalence of positive findings of brain computed tomography scans in pediatric population.

    Jahanshahi, Amirreza / Sadeghvand, Shahram / Khalafi, Mohammad / Jafarzadeh, Alireza / Zarrintan, Armin

    Iranian journal of child neurology

    2023  Band 17, Heft 2, Seite(n) 111–117

    Abstract: Objectives: Computed tomography (CT) scans are used more frequently in medical centers, increasing unnecessary requests for it as a first-line evaluation. This study aimed to investigate the rate and prevalence of abnormal findings in a brain CT scan in ...

    Abstract Objectives: Computed tomography (CT) scans are used more frequently in medical centers, increasing unnecessary requests for it as a first-line evaluation. This study aimed to investigate the rate and prevalence of abnormal findings in a brain CT scan in children at the Children's Hospital of Tabriz, Iran.
    Materials &methods: This study was a cross-sectional descriptive-analytical study that included all children under 15 years old undergoing a brain CT scan at the Children's Hospital of Tabriz, Iran. All patients who fulfilled the inclusion criteria and were referred to the Children's Hospital of Tabriz during the spring of 2018 entered the study. Age, gender, patient history, and clinical findings were examined. In the next step, the results of each patient's CT scan were evaluated.
    Results: In this study, 108 patients were studied with a median age of 18.0 months. CT scan results were normal in seventy-four cases (68.5%), hydrocephalus was seen in 15 (13.9%), and benign infantile hydrocephalus was seen in eight (7.4%). The study revealed a statistically significant relationship between patient history and CT scan results (p=0.017). A statistically significant relationship was observed between the clinical findings and CT scan results (p=0.042).
    Conclusion: Brain CT scans have more abnormal findings in patients with positive clinical findings. Although a CT scan is a highly sensitive and specificmodality in diagnosing central nervous system (CNS) abnormalities, its value depends on the underlying medical history and physical exam.
    Sprache Englisch
    Erscheinungsdatum 2023-03-15
    Erscheinungsland Iran
    Dokumenttyp Journal Article
    ZDB-ID 2542305-8
    ISSN 2008-0700 ; 1735-4668
    ISSN (online) 2008-0700
    ISSN 1735-4668
    DOI 10.22037/ijcn.v17i1.36227
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  3. Artikel ; Online: Region-specific interobserver agreement of the Alberta Stroke Program Early Computed Tomography Score: A meta-analysis.

    Zarrintan, Armin / Ibrahim, Mohamed K / Hamouda, Noha / Jabal, Mohamed Sobhi / Beizavi, Zahra / Ghozy, Sherief / Kallmes, David F

    Journal of neuroimaging : official journal of the American Society of Neuroimaging

    2024  Band 34, Heft 2, Seite(n) 195–204

    Abstract: Background and purpose: The Alberta Stroke Program Early CT Score (ASPECTS) is a widely used scoring system for evaluating ischemic stroke to determine therapeutic strategy. However, there is variation in the interobserver agreement of ASPECTS. This ... ...

    Abstract Background and purpose: The Alberta Stroke Program Early CT Score (ASPECTS) is a widely used scoring system for evaluating ischemic stroke to determine therapeutic strategy. However, there is variation in the interobserver agreement of ASPECTS. This systematic review and meta-analysis aimed to investigate the interobserver agreement of total and regional ASPECTS.
    Methods: A comprehensive search was conducted in the Web of Sciences, PubMed, and Scopus databases to identify relevant studies. Inclusion criteria were studies of noncontrast CT performed within 24 hours of ischemic stroke in the middle cerebral artery territory.
    Results: A total of 20 studies, with 3482 patients, reporting interobserver agreement of total and regional ASPECTS were included in the meta-analysis. The interobserver agreement for total ASPECTS in studies using Kappa coefficient (κ) analysis was substantial (κ = .67, 95% confidence interval [CI]: .57-.78). In studies using intraclass correlation coefficient (ICC) analysis, agreement was excellent (ICC = .84, 95% CI: .77-.90). Interobserver agreement was higher in studies in which the observer was unblinded to clinical scenario in both groups (κ = .74, 95% CI: .59-.89, and ICC = .82, 95% CI: .79-.85). Per-region analysis showed that the caudate nucleus had the highest agreement (κ = .68, 95% CI: .60-.76, and ICC = .84, 95% CI: .74-.93), while M2 and internal capsule in Kappa studies (κ = .45, 95% CI: .34-.55 and κ = .47, 95% CI: .28-.66), and M4 and internal capsule in ICC studies (ICC = .54, 95% CI: .43-.64 and ICC = .55, 95% CI: .18-.91) had the lowest agreement.
    Conclusion: This meta-analysis demonstrates substantial to excellent interobserver agreement for total ASPECTS, which supports using this method for stroke treatment. However, findings emphasize the need to consider interobserver agreement in specific regions of ASPECTS for treatment decisions.
    Mesh-Begriff(e) Humans ; Alberta ; Observer Variation ; Stroke/diagnostic imaging ; Tomography, X-Ray Computed/methods ; Ischemic Stroke ; Reproducibility of Results ; Retrospective Studies
    Sprache Englisch
    Erscheinungsdatum 2024-01-07
    Erscheinungsland United States
    Dokumenttyp Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 1071724-9
    ISSN 1552-6569 ; 1051-2284
    ISSN (online) 1552-6569
    ISSN 1051-2284
    DOI 10.1111/jon.13184
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Changes in brain MRI under different lunar cycles: a cross-sectional study

    Malek, Ayyoub / Daghighi, Mohammad Hossein / Pourisa, Masoud / Pourmohammadi, Tohid / Dastgiri, Saeed / Nezami, Nariman / Mirza-Aghazadeh-Attari, Mohammad / Arasteh, Amin / Zarrintan, Armin

    Biological rhythm research. 2022 May 04, v. 53, no. 5

    2022  

    Abstract: Physiologic changes in mammals, including humans, are known to vary as a function of different lunar cycle phases. Importantly, the structure of the central nervous system (CNS) affects its functional status. A total of 15 healthy volunteers underwent ... ...

    Abstract Physiologic changes in mammals, including humans, are known to vary as a function of different lunar cycle phases. Importantly, the structure of the central nervous system (CNS) affects its functional status. A total of 15 healthy volunteers underwent magnetic resonance imaging (MRI) in each of the lunar cycles, with each subject undergoing a total of four imaging sessions. Size and volume of structures such as the hippocampus, subarachnoid space, lentiform nucleus, thalamus, and trigon, were measured by expert radiologists. Inter-phase differences in size and volume were determined. There was a significant difference between ventricular volume, whole-brain volume, hippocampal volume, lentiform nuclei volume, and thalamus diameter between the four lunar phases. The new moon had the lowest values than any other lunar phase in any reported structures. Importantly, the difference between the new moon and the third quarter lunar phase was always significant. There was no significant difference in subarachnoid space volume and trigone diameter of the ventricles in different lunar phases. The trigone was the smallest in the third quarter lunar phase. Our results suggest that lunar phases affect brain structures.
    Schlagwörter biological rhythms ; cross-sectional studies ; functional status ; hippocampus ; magnetism ; research ; thalamus
    Sprache Englisch
    Erscheinungsverlauf 2022-0504
    Umfang p. 823-829.
    Erscheinungsort Taylor & Francis
    Dokumenttyp Artikel
    ZDB-ID 1185065-6
    ISSN 1744-4179 ; 0929-1016
    ISSN (online) 1744-4179
    ISSN 0929-1016
    DOI 10.1080/09291016.2020.1871546
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  5. Artikel: Primary pleural lymphoma of T cell origin in a paediatric patient with a focus on radiological findings - a case report and review of literature.

    Jahanshahi, Amirreza / Hiradfar, Amirataollah / Zarrintan, Armin / Mirza-Aghazadeh-Attari, Mohammad

    Polish journal of radiology

    2019  Band 84, Seite(n) e353–e359

    Abstract: Purpose: Pleural lymphoma is a medical condition characterised by shortness of breath and obscure chest pain, which may be a diagnostic challenge, especially when it occurs in children. Plain chest X-rays and computed tomography (CT) scan are the main ... ...

    Abstract Purpose: Pleural lymphoma is a medical condition characterised by shortness of breath and obscure chest pain, which may be a diagnostic challenge, especially when it occurs in children. Plain chest X-rays and computed tomography (CT) scan are the main imaging techniques and are the initial diagnostic methods utilised.
    Case report: A four-year-old boy was admitted to the emergency ward with pain in the right thoracoabdominal region, which had persisted for two months. Physical examination revealed reduced respiratory sounds in the right chest, but with no other significant findings. The patient underwent chest X-ray and CT scan, which showed right sided pleural thickening coupled with a massive pleural effusion. The patient underwent pleural biopsy, and a diagnosis of T-cell primary pleural lymphoma was made. The patient underwent treatment with BFM-NHL and was followed for three years, during which the patient remained disease free.
    Conclusions: Pleural lymphoma is a rare diagnosis especially in children and could have overlapping clinical manifestations with more common conditions. Imaging techniques are the main route of clinical work-up towards final diagnosis. Here, we present a rare paediatric patient with no significant past medical history, who underwent imaging and was diagnosed with T-cell primary pleural lymphoma, a very rare subtype of primary pleural lymphoma.
    Sprache Englisch
    Erscheinungsdatum 2019-09-16
    Erscheinungsland Poland
    Dokumenttyp Case Reports
    ZDB-ID 2675143-4
    ISSN 1899-0967 ; 1733-134X
    ISSN (online) 1899-0967
    ISSN 1733-134X
    DOI 10.5114/pjr.2019.88773
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Breast artery calcification as a predictor of coronary artery calcification: a cross-sectional study.

    Seifi, Batool / Javadrashid, Reza / Seifi, Fatemeh / Khamanian, Jhila / Zarrintan, Armin / Mirza-Aghazadeh-Attari, Mohammad

    Polish journal of radiology

    2020  Band 85, Seite(n) e369–e374

    Abstract: Introduction: Coronary artery disease is the main cause of burden of disease in the world. Coronary calcification is seen as an aetiopathological event in the pathogenesis of cardiovascular diseases. Studies have shown that breast artery calcification, ... ...

    Abstract Introduction: Coronary artery disease is the main cause of burden of disease in the world. Coronary calcification is seen as an aetiopathological event in the pathogenesis of cardiovascular diseases. Studies have shown that breast artery calcification, which is routinely found in mammography of elderly women, could be predictive of coronary artery calcification.
    Material and methods: In this cross-sectional study, 60 women over 40 years of age were included. All of these patients had undergone mammography after having an indication to undergo a computed tomography-angiography. Breast arterial calcification and calcium scores were determined for each patient, and the paired-
    Results: The mean age of patients was 49.52 ± 8.83 years. Of these 60 women, 50% were postmenopausal and 50% were not. In 37 (61.7%) cases, mild to severe coronary calcification was observed, and 50 (83.3%) had mild to severe breast arterial calcification. There was a significant correlation between coronary calcification and breast artery calcification (
    Conclusions: Breast artery calcification can be a suitable predictor for coronary artery calcification and is a valid method for predicting cardiovascular disease probability in the future.
    Sprache Englisch
    Erscheinungsdatum 2020-07-20
    Erscheinungsland Poland
    Dokumenttyp Journal Article
    ZDB-ID 2675143-4
    ISSN 1899-0967 ; 1733-134X
    ISSN (online) 1899-0967
    ISSN 1733-134X
    DOI 10.5114/pjr.2020.97932
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  7. Artikel: Diagnostic value of chest CT in Iranian patients with suspected COVID-19.

    Salehi-Pourmehr, Hanieh / Pourfathi, Hojjat / Tarzamni, Mohammad Kazem / Ghojazadeh, Morteza / Naghili, Behrooz / Zarrintan, Armin / Mahdipour, Reza / Hajebrahimi, Sakineh

    Caspian journal of internal medicine

    2021  Band 11, Heft Suppl 1, Seite(n) 527–530

    Abstract: Background: In the current COVID-19 pandemic, there is a rising need for a rapid and reliable diagnostic tool. We hypothesized that chest computed tomography (CT) can be a potential alternative for reverse transcription-polymerase chain reaction (RT-PCR) ...

    Abstract Background: In the current COVID-19 pandemic, there is a rising need for a rapid and reliable diagnostic tool. We hypothesized that chest computed tomography (CT) can be a potential alternative for reverse transcription-polymerase chain reaction (RT-PCR). The aim of this study was to compare the diagnostic value of chest CT and RT-PCR in Iranian patients with suspected COVID-19.
    Methods: In a retrospective, single-center case series, 568 consecutive hospitalized or outpatient patients with suspected COVID-19 underwent chest CT and/or RT-PCR testing at Imam Reza Hospital, the tertiary teaching hospital of Tabriz University of Medical Sciences in Iran, from February 21 and March 28, 2020.
    Results: The sensitivity of chest CT for signifying COVID-19 was 64% (95% CI: 56%-71%) on the basis of positive RT-PCR results as a standard method. CT imaging also had a specificity of 77% (95% CI: 73%-81%), positive predictive value of 35% (95% CI: 0.31-0.39), negative predictive value of 66% (95% CI: 0.61-0.69), positive likelihood ratio of 2.79 (95% CI: 2.26-3.46), and negative likelihood ratio of 0.47 (95% CI: 0.38-0.57).
    Conclusion: Chest CT had higher specificity in the diagnosis of COVID-19 than that of the previous studies. Therefore, it can play a crucial role in the early diagnosis. Similar to the previous studies, the typical CT features were patchy ground-glass opacities as well as peripheral aspects of the lungs consolidations.
    Sprache Englisch
    Erscheinungsdatum 2021-01-01
    Erscheinungsland Iran
    Dokumenttyp Journal Article
    ZDB-ID 2971933-1
    ISSN 2008-6172 ; 2008-6164
    ISSN (online) 2008-6172
    ISSN 2008-6164
    DOI 10.22088/cjim.11.0.527
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  8. Artikel: Clinical Experience, Pathophysiology, and Considerations in the Prophylaxis and Treatment of Hypercoagulopathy of COVID-19: A Review Study.

    Pourafkari, Leili / Mirza-Aghzadeh-Attari, Mohammad / Zarrintan, Armin / Mousavi-Aghdas, Seyed Ali

    Iranian journal of medical sciences

    2019  Band 46, Heft 1, Seite(n) 1–14

    Abstract: Since the emergence of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic, an increasing number of reports and studies have tried to warn the medical community about the thrombotic complications of coronavirus disease 2019 (COVID- ... ...

    Abstract Since the emergence of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic, an increasing number of reports and studies have tried to warn the medical community about the thrombotic complications of coronavirus disease 2019 (COVID-19). It is suggested that the hyperinflammatory response and endothelial injury, especially in patients with severe disease, lead to a hypercoagulable state. Sudden deaths occurring in some patients also point to fulminant arrhythmias and massive pulmonary embolism (PE). Several expert panels have published recommendations regarding the prophylaxis and treatment of such complications. Nonetheless, there are limited high-quality studies for evidence-based decision-making, and most of these recommendations have arisen from descriptive studies, and optimal anticoagulant agents and dosages are yet to be designated. The coagulopathy persists after the acute phase of the illness, and some panels recommend the continuation of deep vein thrombosis prophylaxis for several days after regaining the normal daily activities by the patient. Here, we review the incidence and possible mechanisms of thrombotic complications, and present a summary of the considerations for the prophylaxis and treatment of such complications in the adult population.
    Mesh-Begriff(e) Anticoagulants/administration & dosage ; COVID-19/complications ; Humans ; Incidence ; Platelet Aggregation Inhibitors ; Risk Factors ; Thrombophilia/drug therapy ; Thrombophilia/prevention & control ; Venous Thromboembolism
    Chemische Substanzen Anticoagulants ; Platelet Aggregation Inhibitors
    Sprache Englisch
    Erscheinungsdatum 2019-07-22
    Erscheinungsland Iran
    Dokumenttyp Journal Article ; Review
    ZDB-ID 603872-4
    ISSN 1735-3688 ; 0253-0716
    ISSN (online) 1735-3688
    ISSN 0253-0716
    DOI 10.30476/ijms.2020.87233.1730
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  9. Artikel: Computed tomography imaging findings in hospitalized patients with coronavirus disease 2019 (COVID-19): a descriptive study of 81 cases.

    Zarrintan, Armin / Javadrashid, Reza / Jalili, Javad / Hajebrahimi, Sakineh / Varshochi, Mojtaba / Hajalioghli, Parisa / Seifi, Batool / Mirza-Aghazadeh-Attari, Mohammad / Tarzamni, Mohammad Kazem

    Polish journal of radiology

    2021  Band 86, Seite(n) e165–e171

    Abstract: Purpose: Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has proven to be a diagnostic challenge. Early studies have shown that computed tomography (CT) imaging may be useful in diagnosis of these patients. We aim to report CT findings in a ...

    Abstract Purpose: Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has proven to be a diagnostic challenge. Early studies have shown that computed tomography (CT) imaging may be useful in diagnosis of these patients. We aim to report CT findings in a series of hospitalized patients.
    Material and methods: A total of 81 patients were included in this study. All of the patients were hospitalized and had SARS-CoV-2 infection proven by molecular assay. All patients had a CT scan on the first day of admission. Imaging results were reviewed by two separate radiologists, and imaging findings were documented.
    Results: Seventy-eight patients had abnormal CT imaging, while 3 had normal CT imaging. The sensitivity of CT in diagnosing coronavirus disease 2019 (COVID-19) was estimated to be 96%. The most common imaging finding was ground glass opacities, followed by septal thickening. Most lesions were located at the periphery and posterior of the lungs. Most lesions were multifocal, and involved the right lower lobe more frequently. Chest X-rays were normal in 38 patients, and the sensitivity of chest X-ray in diagnosing SARS-Cov-2 was 54%.
    Conclusions: CT scans could be used in diagnosis of patients with a high sensitivity (93%). No common imaging findings may also be seen alongside ground glass opacities, based on the degree of disease progression.
    Sprache Englisch
    Erscheinungsdatum 2021-03-19
    Erscheinungsland Poland
    Dokumenttyp Journal Article
    ZDB-ID 2675143-4
    ISSN 1899-0967 ; 1733-134X
    ISSN (online) 1899-0967
    ISSN 1733-134X
    DOI 10.5114/pjr.2021.104584
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  10. Artikel ; Online: Rapidly progressive COVID-19 viral pneumonia

    Zarrintan, Armin / Javadrashid, Reza / Tarzamni, Mohammad Kazem / Zarrintan, Anita / Falahatian, Masih / Mirza-Aghazadeh-Attari, Mohammad

    Egyptian Journal of Radiology and Nuclear Medicine

    a report of two patients with a focus on imaging findings

    2020  Band 51, Heft 1

    Schlagwörter covid19
    Sprache Englisch
    Verlag Springer Science and Business Media LLC
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ZDB-ID 2583928-7
    ISSN 2090-4762 ; 0378-603X
    ISSN (online) 2090-4762
    ISSN 0378-603X
    DOI 10.1186/s43055-020-00225-y
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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