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  1. Article: Carcinosarcoma of the Mediastinum: A Rare Cause of Vocal Cord Palsy and Progressive Dysphagia.

    Kanesan, Nithya / Mohamad, Irfan / Mohamad Umbaik, Norsyamira Aida / Zawawi, Norzaliana

    Medeniyet medical journal

    2020  Volume 35, Issue 2, Page(s) 166–169

    Abstract: Carcinosarcoma is a rare type of malignant tumour that possess both the elements of carcinoma and sarcoma. They may occur in various locations such as the uterus, breast, thyroid, lung and gastrointestinal system. However, very few primary mediastinal ... ...

    Abstract Carcinosarcoma is a rare type of malignant tumour that possess both the elements of carcinoma and sarcoma. They may occur in various locations such as the uterus, breast, thyroid, lung and gastrointestinal system. However, very few primary mediastinal carcinosarcomas have been reported. We are presenting a case of a 75-year-old male who presented with progressive dysphagia and hoarseness for 3 weeks. Contrast-enhanced computed tomography of the neck showed features of enlarged mediastinal necrotic nodes and the biopsy of this mass showed morphology and immunohistochemical profile that are consistent with carcinosarcoma. However, the patient succumbed to his illness soon after diagnosis.
    Language English
    Publishing date 2020-06-30
    Publishing country Turkey
    Document type Case Reports
    ZDB-ID 3035195-9
    ISSN 2149-4606 ; 2149-2042
    ISSN (online) 2149-4606
    ISSN 2149-2042
    DOI 10.5222/MMJ.2020.82956
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Giant solitary juvenile polyp: from obstructed defecation syndrome to incontinence.

    Teoh, Zhan Huai / Soh, Jien Yen / Mohamad, Nasibah / Zawawi, Norzaliana / Zakaria, Andee Dzulkarnaen / Zakaria, Zaidi / Wong, Michael Pak-Kai

    Annals of coloproctology

    2022  

    Abstract: Juvenile polyps (JPs) are the most common polyps in pediatric patients. We present the case of an 18-year-old male patient with a giant solitary JP resembling solitary rectal ulcer syndrome (SRUS). The presenting history was rectal bleeding and symptoms ... ...

    Abstract Juvenile polyps (JPs) are the most common polyps in pediatric patients. We present the case of an 18-year-old male patient with a giant solitary JP resembling solitary rectal ulcer syndrome (SRUS). The presenting history was rectal bleeding and symptoms of obstructed defecation syndrome. Colonoscopy revealed a polypoidal mass at the anorectal junction, with biopsy-confirmed SRUS. The symptoms worsened, and a protruding mass from the anus caused fecal incontinence. Pelvic magnetic resonance imaging showed a huge pedunculated mass occupying the low rectum with local compression of the urinary bladder. Transanal excision of the anal tumor was performed due to bleeding. A histopathological examination showed a JP with high-grade dysplasia. A histological examination to differentiate JPs and SRUS could be challenging based on a superficial forceps biopsy. Therefore, an excision biopsy is usually warranted with the understanding that adenomatous or malignant transformation is found in 5.6% to 12% of all JPs.
    Language English
    Publishing date 2022-11-25
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2711906-3
    ISSN 2287-9722 ; 2287-9714
    ISSN (online) 2287-9722
    ISSN 2287-9714
    DOI 10.3393/ac.2022.00549.0078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A Rare Manifestation of Cervical Yolk Sac Tumor in an Unfortunate Infant.

    Saniasiaya, Jeyasakthy / Hamid, Suzina Sheikh Ab / Mohamad, Hazama / Wahab, Wan Nur Najmiyah Wan Abdul / Zawawi, Norzaliana

    Turkish archives of otorhinolaryngology

    2019  Volume 57, Issue 3, Page(s) 157–160

    Abstract: Paediatric germ cell tumor is composed of various neoplasms which exhibit capricious clinical presentation and histological features depending on the age and the area of presentation. Yolk sac tumor is an extremely rare malignant tumor of embryonic ... ...

    Abstract Paediatric germ cell tumor is composed of various neoplasms which exhibit capricious clinical presentation and histological features depending on the age and the area of presentation. Yolk sac tumor is an extremely rare malignant tumor of embryonic origin which usually arises from the gonads. Its manifestation in the head and neck region is extremely rare. Here, we report a rare case of the malignant transformation of mature teratoma into yolk sac tumor of the neck in an infant. Diagnosis was confirmed following histopathological examination of the neck mass along with marked increase of the serum alpha-fetoprotein. The child unfortunately succumbed prior to chemotherapy. We highlight the challenge we faced in diagnosing and managing this rare entity. We would also like to recommend serial monitoring of serum alpha-fetoprotein in all patients with mature teratoma to detect malignant transformation early.
    Language English
    Publishing date 2019-09-01
    Publishing country Turkey
    Document type Case Reports
    ISSN 2667-7474
    ISSN (online) 2667-7474
    DOI 10.5152/tao.2019.3900
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Melanocytic variant of medullary thyroid carcinoma in a previously treated papillary carcinoma patient.

    Mohamad, Irfan / Zainuddin, Nazli / Zawawi, Norzaliana / Naik, Venkatesh R

    Annals of the Academy of Medicine, Singapore

    2011  Volume 40, Issue 6, Page(s) 300–301

    MeSH term(s) Calcitonin ; Carcinoma, Papillary/drug therapy ; Carcinoma, Papillary/pathology ; Carcinoma, Papillary/surgery ; Female ; Humans ; Melanins ; Melanocytes/cytology ; Melanocytes/pathology ; Middle Aged ; Prognosis ; S100 Proteins ; Thyroid Neoplasms/drug therapy ; Thyroid Neoplasms/pathology
    Chemical Substances Melanins ; S100 Proteins ; Calcitonin (9007-12-9)
    Language English
    Publishing date 2011-07-19
    Publishing country Singapore
    Document type Case Reports ; Letter
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    Database MEDical Literature Analysis and Retrieval System OnLINE

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