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  1. Article: A Rare Case of Septic Ovarian Thrombophlebitis Caused by Tissierella praeacuta.

    Chandok, Taruna / Kasule, Sabirah N / Kelly, Paul J / Gonzalez, Efrain / Chilimuri, Sridhar S / Zeana, Cosmina B

    Cureus

    2023  Volume 15, Issue 7, Page(s) e42385

    Abstract: We report a case ... ...

    Abstract We report a case of
    Language English
    Publishing date 2023-07-24
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.42385
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The use of Vaccinia Immune Globulin in the Treatment of Severe Mpox. Virus Infection in Human Immunodeficiency Virus/AIDS.

    Thet, Andrea K / Kelly, Paul J / Kasule, Sabirah N / Shah, Anish K / Chawala, Arpan / Latif, Amber / Chilimuri, Sridhar S / Zeana, Cosmina B

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2022  Volume 76, Issue 9, Page(s) 1671–1673

    Abstract: We report a case of progressive, severe mpox virus (MPXV) infection in a patient with AIDS despite a standard course of tecovirimat. He significantly improved after administration of vaccinia immune globulin intravenous (VIGIV) highlighting its use as an ...

    Abstract We report a case of progressive, severe mpox virus (MPXV) infection in a patient with AIDS despite a standard course of tecovirimat. He significantly improved after administration of vaccinia immune globulin intravenous (VIGIV) highlighting its use as an adjunct for severe disease in immunocompromised hosts.
    MeSH term(s) Male ; Humans ; Vaccinia/therapy ; Acquired Immunodeficiency Syndrome ; HIV ; Mpox (monkeypox) ; Immunoglobulins ; Immunologic Factors
    Chemical Substances Immunoglobulins ; Immunologic Factors
    Language English
    Publishing date 2022-12-27
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciac971
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Cluster of bloodstream infections caused by KPC-2 carbapenemase-producing Klebsiella pneumoniae in Manhattan.

    Nadkarni, Abhijeet S / Schliep, Tjark / Khan, Lamia / Zeana, Cosmina B

    American journal of infection control

    2009  Volume 37, Issue 2, Page(s) 121–126

    Abstract: Background: Carbapenems are considered the agents of choice for treatment of serious infections caused by resistant gram-negative organisms. A new group of class A beta-lactamases, known as KPC-type carbapenemases, has recently been described and poses ... ...

    Abstract Background: Carbapenems are considered the agents of choice for treatment of serious infections caused by resistant gram-negative organisms. A new group of class A beta-lactamases, known as KPC-type carbapenemases, has recently been described and poses a serious clinical challenge.
    Methods: Seven patients with bloodstream infections caused by Klebsiella pneumoniae isolates with decreased susceptibility to carbapenems were identified between January and April 2005 in the intensive care units of a hospital in Manhattan. Isolate identification and susceptibility testing were performed according to National Committee for Clinical Laboratory Standards methodology. All isolates were ribotyped and screened for (bla)KPC by polymerase chain reaction. The polymerase chain reaction product underwent nucleotide sequencing for one of the isolates. Medical records were reviewed retrospectively.
    Results: Six isolates were carbapenem-resistant with minimum inhibitory concentrations for imipenem of >8microg/mL. Ribotyping showed that all isolates belonged to a single clone. All isolates possessed (bla)KPC and nucleotide sequencing identified the allelic type KPC-2. Patients' median age was 68 years. The median duration of hospitalization was 25.5 days before the first positive blood culture. Five of 6 patients received previous broad-spectrum beta-lactam antibiotics but none received prior carbapenems. Five of 6 isolates were susceptible to polymyxin B. Three of the 5 patients were treated with polymyxin B and 1 survived. Overall, only 2 of the 6 patients survived.
    Conclusion: This report describes the first outbreak of KPC-2 carbapenemase-producing K pneumoniae bloodstream infections in a hospital in Manhattan.
    MeSH term(s) Aged ; Aged, 80 and over ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Bacteremia/epidemiology ; Bacteremia/microbiology ; Bacterial Typing Techniques ; Carbapenems/pharmacology ; Cluster Analysis ; Cross Infection/epidemiology ; Cross Infection/microbiology ; DNA Fingerprinting ; DNA, Bacterial/genetics ; Female ; Genotype ; Hospitals ; Humans ; Intensive Care Units ; Klebsiella Infections/epidemiology ; Klebsiella Infections/microbiology ; Klebsiella pneumoniae/classification ; Klebsiella pneumoniae/enzymology ; Klebsiella pneumoniae/genetics ; Klebsiella pneumoniae/isolation & purification ; Male ; Microbial Sensitivity Tests ; Middle Aged ; New York City/epidemiology ; Polymyxin B/therapeutic use ; Ribotyping ; Sequence Analysis, DNA ; beta-Lactam Resistance ; beta-Lactamases/biosynthesis
    Chemical Substances Anti-Bacterial Agents ; Carbapenems ; DNA, Bacterial ; Polymyxin B (1404-26-8) ; beta-lactamase KPC-2 (EC 3.5.2.-) ; beta-Lactamases (EC 3.5.2.6)
    Language English
    Publishing date 2009-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2007.10.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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