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  1. Article ; Online: Schrödinger's mousetrap. Part 5.

    Zegers, Remco

    Nature

    2005  Volume 433, Issue 7027, Page(s) 689

    Language English
    Publishing date 2005-02-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/433689a
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  2. Book ; Online: Constraining the Astrophysical p Process

    Palmisano-Kyle, Alicia / Spyrou, Artemis / DeYoung, Paul / Gastis, Panagiotis / Olivas-Gomez, Orlando / Harris, Caley / Liddick, Sean / Lyons, Stephanie / Pereira, Jorge / Richard, Andrea / Simon, Anna / Smith, Mallory / Tsantiri, Artemis / Zegers, Remco

    Cross Section Measurement of the 84Kr(p,g)85Rb Reaction in Inverse Kinematics

    2023  

    Abstract: One of the biggest questions in nuclear astrophysics is understanding where the elements come from and how they are made. This work focuses on the p process, a nucleosynthesis process that consists of a series of photodisintegration reactions responsible ...

    Abstract One of the biggest questions in nuclear astrophysics is understanding where the elements come from and how they are made. This work focuses on the p process, a nucleosynthesis process that consists of a series of photodisintegration reactions responsible for producing stable isotopes on the proton-rich side of stability. These nuclei, known as the p nuclei, cannot be made through the well-known neutron-capture processes. Currently p-process models rely heavily on theory to provide the relevant reaction rates to predict the final p-nuclei abundances and more experimental data is needed. The present work reports on an experiment performed with the SuN detector at the National Superconducting Cyclotron Laboratory, NSCL, at Michigan State University using the ReA facility to measure the $^{84}$Kr(p,$\gamma$)$^{85}$Rb reaction cross section in inverse kinematics. The reverse $^{85}$Rb($\gamma$,p)$^{84}$Kr reaction is a branching point in the p-process reaction network that was highlighted as an important reaction in sensitivity studies in the production of the $^{78}$Kr p nucleus. A new hydrogen gas target was designed and fabricated and a new analysis technique for background subtraction and efficiency calculations of the detector were developed. The experimental cross section is compared to standard statistical model calculations using the NON-SMOKER and TALYS codes.
    Keywords Nuclear Experiment
    Subject code 660
    Publishing date 2023-03-13
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Electron Capture and Beta-Decay Rates for the Collapse of O+Ne+Mg Cores

    Hua Lam Yi / Martínez-Pinedo Gabriel / Langanke Karlheinz / Jones Samuel / Hirschi Raphael / Zegers Remco G. T. / Alex Brown B.

    EPJ Web of Conferences, Vol 66, p

    2014  Volume 07011

    Abstract: We present a new set of electron (e−) capture and β-decay rates that improves previous calculations by Takahara et al. and Oda et al. by: (a) incorporation of recent charge-exchange and β-decay data, (b) contributions of forbidden transitions, and (c) ... ...

    Abstract We present a new set of electron (e−) capture and β-decay rates that improves previous calculations by Takahara et al. and Oda et al. by: (a) incorporation of recent charge-exchange and β-decay data, (b) contributions of forbidden transitions, and (c) inclusion of e− screening corrections. The experimental nuclear input is supplemented by theoretical data based on large-scale shell model calculations in the full sd-shell space using the USDB interaction. The impact of these new rates on the late-stage stellar evolution of 8.8M⊙ star is demonstrated.
    Keywords Physics ; QC1-999 ; Science ; Q
    Language English
    Publishing date 2014-03-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Thesis: Search for isovector giant monopole resonances

    Zegers, Remco Godfried Theo

    1999  

    Author's details Remco Godfried Theo Zegers
    Language English
    Size 158 S, Ill., graph. Darst
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Groningen, 1999
    Accompanying material Stellingen
    Database Former special subject collection: coastal and deep sea fishing

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  5. Article: Kwashiorkor and marasmus are both associated with impaired glucose clearance related to pancreatic β-cell dysfunction

    Spoelstra, Martijn N / Mari, Andrea / Mendel, Marijke / Senga, Edward / van Rheenen, Patrick / van Dijk, Theo H / Reijngoud, Dirk-Jan / Zegers, Remco G.T / Heikens, Geert Tom / Bandsma, Robert H.J

    Metabolism, clinical and experimental. 2012 Sept., v. 61, no. 9

    2012  

    Abstract: Severe malnutrition is a major health problem in developing countries and can present as kwashiorkor or marasmus. Kwashiorkor is associated with septicaemia, profound metabolic changes including hepatic steatosis, altered protein metabolism and increased ...

    Abstract Severe malnutrition is a major health problem in developing countries and can present as kwashiorkor or marasmus. Kwashiorkor is associated with septicaemia, profound metabolic changes including hepatic steatosis, altered protein metabolism and increased oxidative stress. Limited data suggest that children with kwashiorkor have an impaired glucose tolerance and insulin secretion. Our objective was to determine glucose tolerance in children with kwashiorkor compared to marasmus and its relation to insulin secretion and sensitivity. Six children with kwashiorkor and 8 children with marasmus were studied. We were also able to include 3 healthy children for comparison. They received a primed (13mg/kg), constant infusion (0.15mg/kg/min) of [6,6-²H₂]glucose for 4h with serial blood sampling. In addition, an oral glucose tolerance test (OGTT) was performed with labeled 10mg/g [U-¹³C]glucose. Glucose clearance was determined using mathematical modeling. Glucose clearance rates during the OGTT were −392 (range 309) mL/kg in children with kwashiorkor, −156 (426) mL/kg in marasmus and 279 (345) mL/kg in the control group. Glucose clearance rates correlated with plasma albumin concentrations (r=0.67, P=.001). Insulin responses were strongly impaired in both kwashiorkor and marasmus. There was no indication of peripheral or hepatic insulin resistance in the malnourished groups. We show that glucose clearance rates are affected in both children with marasmus as well as kwashiorkor, which correlate with plasma albumin concentrations. The disturbed glucose clearance in malnutrition is related to an impairment in insulin availability.
    Keywords albumins ; blood sampling ; children ; developing countries ; fatty liver ; glucose ; glucose tolerance ; glucose tolerance tests ; insulin ; insulin resistance ; insulin secretion ; islets of Langerhans ; kwashiorkor ; mathematical models ; oxidative stress ; protein metabolism ; septicemia
    Language English
    Dates of publication 2012-09
    Size p. 1224-1230.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 80230-x
    ISSN 1532-8600 ; 0026-0495
    ISSN (online) 1532-8600
    ISSN 0026-0495
    DOI 10.1016/j.metabol.2012.01.019
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  6. Article ; Online: Kwashiorkor and marasmus are both associated with impaired glucose clearance related to pancreatic β-cell dysfunction.

    Spoelstra, Martijn N / Mari, Andrea / Mendel, Marijke / Senga, Edward / van Rheenen, Patrick / van Dijk, Theo H / Reijngoud, Dirk-Jan / Zegers, Remco G T / Heikens, Geert Tom / Bandsma, Robert H J

    Metabolism: clinical and experimental

    2012  Volume 61, Issue 9, Page(s) 1224–1230

    Abstract: Severe malnutrition is a major health problem in developing countries and can present as kwashiorkor or marasmus. Kwashiorkor is associated with septicaemia, profound metabolic changes including hepatic steatosis, altered protein metabolism and increased ...

    Abstract Severe malnutrition is a major health problem in developing countries and can present as kwashiorkor or marasmus. Kwashiorkor is associated with septicaemia, profound metabolic changes including hepatic steatosis, altered protein metabolism and increased oxidative stress. Limited data suggest that children with kwashiorkor have an impaired glucose tolerance and insulin secretion. Our objective was to determine glucose tolerance in children with kwashiorkor compared to marasmus and its relation to insulin secretion and sensitivity. Six children with kwashiorkor and 8 children with marasmus were studied. We were also able to include 3 healthy children for comparison. They received a primed (13 mg/kg), constant infusion (0.15 mg/kg/min) of [6,6-(2)H(2)]glucose for 4 h with serial blood sampling. In addition, an oral glucose tolerance test (OGTT) was performed with labeled 10 mg/g [U-(13)C]glucose. Glucose clearance was determined using mathematical modeling. Glucose clearance rates during the OGTT were -392 (range 309) mL/kg in children with kwashiorkor, -156 (426) mL/kg in marasmus and 279 (345) mL/kg in the control group. Glucose clearance rates correlated with plasma albumin concentrations (r=0.67, P=.001). Insulin responses were strongly impaired in both kwashiorkor and marasmus. There was no indication of peripheral or hepatic insulin resistance in the malnourished groups. We show that glucose clearance rates are affected in both children with marasmus as well as kwashiorkor, which correlate with plasma albumin concentrations. The disturbed glucose clearance in malnutrition is related to an impairment in insulin availability.
    MeSH term(s) Biomarkers/blood ; Blood Glucose/metabolism ; Female ; Glucose Tolerance Test ; Humans ; Infant ; Insulin Resistance ; Insulin-Secreting Cells/metabolism ; Kwashiorkor/blood ; Kwashiorkor/metabolism ; Male ; Protein-Energy Malnutrition/blood ; Protein-Energy Malnutrition/metabolism ; Time Factors
    Chemical Substances Biomarkers ; Blood Glucose
    Language English
    Publishing date 2012-09
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80230-x
    ISSN 1532-8600 ; 0026-0495
    ISSN (online) 1532-8600
    ISSN 0026-0495
    DOI 10.1016/j.metabol.2012.01.019
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