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  1. Article ; Online: [2,2'-Imino-diethano-lato(2-)-κO,N,O'][4-(meth-oxy-carbonyl-meth-yl)phen-yl]boron.

    Zein, Ahmed L / Dawe, Louise N / Georghiou, Paris E

    Acta crystallographica. Section E, Structure reports online

    2010  Volume 66, Issue Pt 10, Page(s) o2646

    Abstract: The title compound, C(13)H(18)BNO(4), was readily obtained from the reaction of methyl 4-boronobenzene acetate with ethano-lamine. A combination of inter-molecular N-H⋯O hydrogen bonds and C-H⋯π inter-actions leads to the pairwise association of mol- ... ...

    Abstract The title compound, C(13)H(18)BNO(4), was readily obtained from the reaction of methyl 4-boronobenzene acetate with ethano-lamine. A combination of inter-molecular N-H⋯O hydrogen bonds and C-H⋯π inter-actions leads to the pairwise association of mol-ecules.
    Language English
    Publishing date 2010-09-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2041947-8
    ISSN 1600-5368 ; 1600-5368
    ISSN (online) 1600-5368
    ISSN 1600-5368
    DOI 10.1107/S1600536810037864
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Enantioselective total synthesis and X-ray structures of the tetrahydroprotoberberine alkaloids (-)-(S)-tetrahydropalmatrubine and (-)-(S)-corytenchine.

    Zein, Ahmed L / Dawe, Louise N / Georghiou, Paris E

    Journal of natural products

    2010  Volume 73, Issue 8, Page(s) 1427–1430

    Abstract: Enantioselective total syntheses and X-ray structures of both (S)-tetrahydropalmatrubine (2) and (S)-corytenchine (3) are reported for the first time. They were both derived from (S)-N-norlaudanidine, a benzyltetrahydroisoquinoline that was synthesized ... ...

    Abstract Enantioselective total syntheses and X-ray structures of both (S)-tetrahydropalmatrubine (2) and (S)-corytenchine (3) are reported for the first time. They were both derived from (S)-N-norlaudanidine, a benzyltetrahydroisoquinoline that was synthesized with high (>95% ee) enantioselectivity using a chiral auxiliary-assisted Bischler-Napieralski cyclization/reduction approach.
    MeSH term(s) Berberine Alkaloids/chemical synthesis ; Berberine Alkaloids/chemistry ; Crystallography, X-Ray ; Molecular Conformation ; Molecular Structure ; Stereoisomerism
    Chemical Substances (S)-tetrahydropalmatrubine ; Berberine Alkaloids ; corytenchine
    Language English
    Publishing date 2010-08-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/np1001169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1144: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article: Synthesis and antimicrobial activity of novel 5-amino-4-cyano-1H-pyrazole and quinazolin-4(3H)-one derivatives.

    Abdel-Aal, Mohamed T / Abdel-Aleem, Abdel-Aleem H / Ibahim, Laila I / Zein, Ahmed L

    Archives of pharmacal research

    2010  Volume 33, Issue 12, Page(s) 1891–1900

    Abstract: New substituted aroylhydrazones (4a-f) were synthesized from the acid hydrazide (3) and the corresponding aldehyde or aldose. 5-Amino-4-cyano-1H-pyrazole derivatives (6a-f) were prepared by the reaction of the aroylhydrazones (4a-f) with malononitrile. ... ...

    Abstract New substituted aroylhydrazones (4a-f) were synthesized from the acid hydrazide (3) and the corresponding aldehyde or aldose. 5-Amino-4-cyano-1H-pyrazole derivatives (6a-f) were prepared by the reaction of the aroylhydrazones (4a-f) with malononitrile. The synthesized compounds were tested for antimicrobial activity against various bacteria and fungi and showed moderate to high inhibition activities. Compounds incorporating a sugar moiety as well as a pyrazolyl ring in their structure displayed the highest antimicrobial activity.
    MeSH term(s) Anti-Infective Agents/chemical synthesis ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/pharmacology ; Aspergillus/drug effects ; Candida albicans/drug effects ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Hydrazones/chemical synthesis ; Hydrazones/chemistry ; Hydrazones/pharmacology ; Microbial Sensitivity Tests ; Molecular Structure ; Pyrazoles/chemical synthesis ; Pyrazoles/chemistry ; Pyrazoles/pharmacology ; Quinazolinones/chemical synthesis ; Quinazolinones/chemistry ; Quinazolinones/pharmacology
    Chemical Substances 5-amino-4-cyano-1H-pyrazole ; Anti-Infective Agents ; Hydrazones ; Pyrazoles ; Quinazolinones
    Language English
    Publishing date 2010-12
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 447623-2
    ISSN 1976-3786 ; 0253-6269
    ISSN (online) 1976-3786
    ISSN 0253-6269
    DOI 10.1007/s12272-010-1202-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 3229: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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