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  1. Book ; Thesis: Untersuchungen zur Sauerstoffverwertungsstörung in der Sepsis

    Zell, Robert

    1. Einfluß von Zytokinen auf die Pyruvatdehydrogenase-Aktivität und den mitochondrialen Oxidations- und Energiestoffwechsel in Kardiomyozyten ; 2. Abschätzung des Sauerstoffverbrauchs im Skelettmuskel von Patienten mit Sepsis

    (Medizin ; [19])

    2001  

    Author's details Robert Zell
    Series title Medizin ; [19]
    Collection
    Keywords Sepsis ; Sauerstoffversorgung
    Subject Sauerstoff ; Blutvergiftung ; Septikämie
    Language German
    Size 135 S. : Ill., graph. Darst., 21 cm
    Publisher Utz, Wiss
    Publishing place München
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis München, Univ., Diss., 2001
    HBZ-ID HT013513040
    ISBN 3-89675-897-7 ; 978-3-89675-897-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2002 A 5942 order for loan Magazin

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  2. Book ; Thesis: Signalstrukturen der enteroviralen Replikation und Translation

    Zell, Roland

    2001  

    Author's details von Roland Zell
    Language German
    Size IV, 159 Bl., Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Jena, Univ., Habil.-Schr., 2001
    HBZ-ID HT013703118
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2003 E 1990 order to use in reading room Magazin

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  3. Article ; Online: Picornaviridae-the ever-growing virus family.

    Zell, Roland

    Archives of virology

    2017  

    Abstract: Picornaviruses are small, nonenveloped, icosahedral RNA viruses with positive-strand polarity. Although the vast majority of picornavirus infections remain asymptomatic, many picornaviruses are important human and animal pathogens and cause diseases that ...

    Abstract Picornaviruses are small, nonenveloped, icosahedral RNA viruses with positive-strand polarity. Although the vast majority of picornavirus infections remain asymptomatic, many picornaviruses are important human and animal pathogens and cause diseases that affect the central nervous system, the respiratory and gastrointestinal tracts, heart, liver, pancreas, skin and eye. A stunning increase in the number of newly identified picornaviruses in the past decade has shown that picornaviruses are globally distributed and infect vertebrates of all classes. Moreover, picornaviruses exhibit a surprising diversity of both genome sequences and genome layouts, sometimes challenging the definition of taxonomic relevant criteria. At present, 35 genera comprising 80 species and more than 500 types are acknowledged. Fifteen species within five new and three existing genera have been proposed in 2017, but more than 50 picornaviruses still remain unassigned.
    Language English
    Publishing date 2017-10-20
    Publishing country Austria
    Document type Journal Article ; Review
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-017-3614-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

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  4. Article: Exploring the Diversity of Plant-Associated Viruses and Related Viruses in Riverine Freshwater Samples Collected in Berlin, Germany.

    Zell, Roland / Groth, Marco / Selinka, Lukas / Selinka, Hans-Christoph

    Pathogens (Basel, Switzerland)

    2023  Volume 12, Issue 12

    Abstract: Plant-infecting RNA viruses from 30 families and floating genera, as well as a great number of uncultured as yet-unclassified plant-associated viruses have been described. Even so, the plant RNA virosphere is still underexplored. RNA extracted from ... ...

    Abstract Plant-infecting RNA viruses from 30 families and floating genera, as well as a great number of uncultured as yet-unclassified plant-associated viruses have been described. Even so, the plant RNA virosphere is still underexplored. RNA extracted from enriched virus particles of 50 L water samples from the Teltow Canal and the Havel River in Berlin, Germany, was sequenced using Illumina next-generation sequencing. Sequences were searched for plant viruses with BLAST and DIAMOND. Phylogenetic analyses were conducted with IQ-TREE 2. Altogether, 647 virus sequences greater than 1 kb were detected and further analyzed. These data revealed the presence of accepted and novel viruses related to
    Language English
    Publishing date 2023-12-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12121458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Picornaviridae—the ever-growing virus family

    Zell, Roland

    Archives of virology. 2018 Feb., v. 163, no. 2

    2018  

    Abstract: Picornaviruses are small, nonenveloped, icosahedral RNA viruses with positive-strand polarity. Although the vast majority of picornavirus infections remain asymptomatic, many picornaviruses are important human and animal pathogens and cause diseases that ...

    Abstract Picornaviruses are small, nonenveloped, icosahedral RNA viruses with positive-strand polarity. Although the vast majority of picornavirus infections remain asymptomatic, many picornaviruses are important human and animal pathogens and cause diseases that affect the central nervous system, the respiratory and gastrointestinal tracts, heart, liver, pancreas, skin and eye. A stunning increase in the number of newly identified picornaviruses in the past decade has shown that picornaviruses are globally distributed and infect vertebrates of all classes. Moreover, picornaviruses exhibit a surprising diversity of both genome sequences and genome layouts, sometimes challenging the definition of taxonomic relevant criteria. At present, 35 genera comprising 80 species and more than 500 types are acknowledged. Fifteen species within five new and three existing genera have been proposed in 2017, but more than 50 picornaviruses still remain unassigned.
    Keywords Picornaviridae ; animal pathogens ; central nervous system ; eyes ; gastrointestinal system ; genome ; heart ; humans ; liver ; nucleotide sequences ; pancreas ; viruses
    Language English
    Dates of publication 2018-02
    Size p. 299-317.
    Publishing place Springer Vienna
    Document type Article
    Note Review
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-017-3614-8
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 70/128: Show issues

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  6. Article ; Online: Hepeliviruses in two waterbodies in Berlin, Germany

    Zell, Roland / Groth, Marco / Selinka, Lukas / Selinka, Hans-Christoph

    Arch Virol. 2023 Jan., v. 168, no. 1 p.9-9

    2023  

    Abstract: The order Hepelivirales comprises RNA viruses of four families (Alphatetraviridae, Benyviridae, Hepeviridae, and Matonaviridae). Sequencing of virus genomes from water samples from the Havel River and the Teltow Canal (Teltowkanal) in Berlin, Germany, ... ...

    Abstract The order Hepelivirales comprises RNA viruses of four families (Alphatetraviridae, Benyviridae, Hepeviridae, and Matonaviridae). Sequencing of virus genomes from water samples from the Havel River and the Teltow Canal (Teltowkanal) in Berlin, Germany, revealed 25 almost complete and 68 partial genomes of viruses presumably belonging to the order Hepelivirales. Only one of these viruses exhibited a relationship to a known member of this order. The members of one virus clade have a polymerase with a permuted order of the conserved palm subdomain motifs resembling the polymerases of permutotetraviruses and birnaviruses. Overall, our study further demonstrates the diversity of hepeliviruses and indicates the enzootic prevalence of hepeliviruses in unknown hosts.
    Keywords Alphatetraviridae ; Benyviridae ; Birnaviridae ; Hepeviridae ; Permutotetraviridae ; RNA ; enzootic diseases ; genome ; rivers ; surface water ; viruses ; Germany
    Language English
    Dates of publication 2023-01
    Size p. 9.
    Publishing place Springer Vienna
    Document type Article ; Online
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-022-05688-0
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

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  7. Article: Picorna-Like Viruses of the Havel River, Germany.

    Zell, Roland / Groth, Marco / Selinka, Lukas / Selinka, Hans-Christoph

    Frontiers in microbiology

    2022  Volume 13, Page(s) 865287

    Abstract: To improve the understanding of the virome diversity of riverine ecosystems in metropolitan areas, a metagenome analysis was performed with water collected in June 2018 from the river Havel in Berlin, Germany. After enrichment of virus particles and RNA ... ...

    Abstract To improve the understanding of the virome diversity of riverine ecosystems in metropolitan areas, a metagenome analysis was performed with water collected in June 2018 from the river Havel in Berlin, Germany. After enrichment of virus particles and RNA extraction, paired-end Illumina sequencing was conducted and assignment to virus groups and families was performed. This paper focuses on picorna-like viruses, the most diverse and abundant group of viruses with impact on human, animal, and environmental health. Here, we describe altogether 166 viral sequences ranging in size from 1 to 11.5 kb. The 71 almost complete genomes are comprised of one candidate iflavirus, one picornavirus, two polycipiviruses, 27 marnaviruses, 27 dicistro-like viruses, and 13 untypeable viruses. Many partial picorna-like virus sequences up to 10.2 kb were also investigated. The sequences of the Havel picorna-like viruses represent genomes of seven of eight so far known
    Language English
    Publishing date 2022-04-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.865287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A proposed division of the family Picornaviridae into subfamilies based on phylogenetic relationships and functional genomic organization.

    Zell, Roland / Knowles, Nick J / Simmonds, Peter

    Archives of virology

    2021  Volume 166, Issue 10, Page(s) 2927–2935

    Abstract: The highly diverse virus family Picornaviridae presently comprises 68 approved genera with 158 species plus many unassigned viruses. In order to better match picornavirus taxonomy to the functional and genomic groupings between genera, the establishment ... ...

    Abstract The highly diverse virus family Picornaviridae presently comprises 68 approved genera with 158 species plus many unassigned viruses. In order to better match picornavirus taxonomy to the functional and genomic groupings between genera, the establishment of five subfamilies (Caphthovirinae, Kodimesavirinae, Ensavirinae, Paavivirinae and Heptrevirinae) is proposed. The subfamilies are defined by phylogenetic analyses of 3CD (precursor of virus-encoded proteinase and polymerase) and P1 (capsid protein precursor) coding sequences and comprise between 7 and 22 currently approved virus genera. Due to the high within-subfamily and between-subfamily divergences of the picornavirus genera, p-distance estimates are unsuited for the demarcation of subfamilies. Members of the proposed subfamilies typically show some commonalities in their genome organisations, including VP1/2A cleavage mechanisms and possession of leader proteins. Other features, such as internal ribosomal entry site types, are more variable within and between members of genera. Some subfamilies are characterised by homology of proteins 1A, 2A, 2B and 3A encoded by members, which do not belong to the canon of orthologous picornavirus proteins. The proposed addition of a subfamily layer to the taxonomy of picornaviruses provides a valuable additional organisational level to the family that acknowledges the existence of higher-level evolutionary groupings of its component genera.
    MeSH term(s) 3C Viral Proteases/genetics ; Amino Acid Sequence ; Capsid Proteins/genetics ; Evolution, Molecular ; Genome, Viral/genetics ; Genomics ; Internal Ribosome Entry Sites/genetics ; Phylogeny ; Picornaviridae/classification ; Picornaviridae/genetics ; Sequence Analysis, DNA
    Chemical Substances Capsid Proteins ; Internal Ribosome Entry Sites ; 3C Viral Proteases (EC 3.4.22.28)
    Language English
    Publishing date 2021-08-04
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-021-05178-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.110: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Hepeliviruses in two waterbodies in Berlin, Germany.

    Zell, Roland / Groth, Marco / Selinka, Lukas / Selinka, Hans-Christoph

    Archives of virology

    2022  Volume 168, Issue 1, Page(s) 9

    Abstract: The order Hepelivirales comprises RNA viruses of four families (Alphatetraviridae, Benyviridae, Hepeviridae, and Matonaviridae). Sequencing of virus genomes from water samples from the Havel River and the Teltow Canal (Teltowkanal) in Berlin, Germany, ... ...

    Abstract The order Hepelivirales comprises RNA viruses of four families (Alphatetraviridae, Benyviridae, Hepeviridae, and Matonaviridae). Sequencing of virus genomes from water samples from the Havel River and the Teltow Canal (Teltowkanal) in Berlin, Germany, revealed 25 almost complete and 68 partial genomes of viruses presumably belonging to the order Hepelivirales. Only one of these viruses exhibited a relationship to a known member of this order. The members of one virus clade have a polymerase with a permuted order of the conserved palm subdomain motifs resembling the polymerases of permutotetraviruses and birnaviruses. Overall, our study further demonstrates the diversity of hepeliviruses and indicates the enzootic prevalence of hepeliviruses in unknown hosts.
    Language English
    Publishing date 2022-12-25
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-022-05688-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.110: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: A proposed division of the family Picornaviridae into subfamilies based on phylogenetic relationships and functional genomic organization

    Zell, Roland / Knowles, Nick J. / Simmonds, Peter

    Archives of virology. 2021 Oct., v. 166, no. 10

    2021  

    Abstract: The highly diverse virus family Picornaviridae presently comprises 68 approved genera with 158 species plus many unassigned viruses. In order to better match picornavirus taxonomy to the functional and genomic groupings between genera, the establishment ... ...

    Abstract The highly diverse virus family Picornaviridae presently comprises 68 approved genera with 158 species plus many unassigned viruses. In order to better match picornavirus taxonomy to the functional and genomic groupings between genera, the establishment of five subfamilies (Caphthovirinae, Kodimesavirinae, Ensavirinae, Paavivirinae and Heptrevirinae) is proposed. The subfamilies are defined by phylogenetic analyses of 3CD (precursor of virus-encoded proteinase and polymerase) and P1 (capsid protein precursor) coding sequences and comprise between 7 and 22 currently approved virus genera. Due to the high within-subfamily and between-subfamily divergences of the picornavirus genera, p-distance estimates are unsuited for the demarcation of subfamilies. Members of the proposed subfamilies typically show some commonalities in their genome organisations, including VP1/2A cleavage mechanisms and possession of leader proteins. Other features, such as internal ribosomal entry site types, are more variable within and between members of genera. Some subfamilies are characterised by homology of proteins 1A, 2A, 2B and 3A encoded by members, which do not belong to the canon of orthologous picornavirus proteins. The proposed addition of a subfamily layer to the taxonomy of picornaviruses provides a valuable additional organisational level to the family that acknowledges the existence of higher-level evolutionary groupings of its component genera.
    Keywords Picornaviridae ; coat proteins ; genome ; genomics ; internal ribosome entry sites ; phylogeny ; proteinases ; taxonomy ; virology ; viruses
    Language English
    Dates of publication 2021-10
    Size p. 2927-2935.
    Publishing place Springer Vienna
    Document type Article
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-021-05178-9
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 70/128: Show issues

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