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  1. Article ; Online: Combined toxicity and adverse outcome pathways of common pesticides on

    Zhang, Jing / Zhang, Jin / Huang, Xianhuai / Xie, Fazhi / Dai, Biya / Ma, Tianyi / Zeng, Jianping

    Environmental science. Processes & impacts

    2024  Volume 26, Issue 3, Page(s) 611–621

    Abstract: Pesticides due to their extensive use have entered the soil and water environment through various pathways, causing great harm to the environment. Herbicides and insecticides are common pesticides with long-term biological toxicity and bioaccumulation, ... ...

    Abstract Pesticides due to their extensive use have entered the soil and water environment through various pathways, causing great harm to the environment. Herbicides and insecticides are common pesticides with long-term biological toxicity and bioaccumulation, which can harm the human body. The concept of the adverse outcome pathway (AOP) involves systematically analyzing the response levels of chemical mixtures to health-related indicators at the molecular and cellular levels. The AOP correlates the structures of chemical pollutants, toxic molecular initiation events and adverse outcomes of biological toxicity, providing a new model for toxicity testing, prediction, and evaluation of pollutants. Therefore, typical pesticides including diquat (DIQ), cyanazine (CYA), dipterex (DIP), propoxur (PRO), and oxamyl (OXA) were selected as research objects to explore the combined toxicity of typical pesticides on
    MeSH term(s) Humans ; Pesticides/toxicity ; Chlorella ; Adverse Outcome Pathways ; Insecticides ; Propoxur/pharmacology ; Environmental Pollutants ; Water Pollutants, Chemical/pharmacology
    Chemical Substances Pesticides ; Insecticides ; Propoxur (BFH029TL73) ; Environmental Pollutants ; Water Pollutants, Chemical
    Language English
    Publishing date 2024-03-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2703814-2
    ISSN 2050-7895 ; 2050-7887
    ISSN (online) 2050-7895
    ISSN 2050-7887
    DOI 10.1039/d3em00525a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Changes of bile acids and resting energy expenditure after laparoscopic cholecystectomy in type 2 diabetes patients: a prospective study.

    Yin, Haixin / Chen, Weijie / He, Xiaodong / Zeng, Jianping

    Diabetology & metabolic syndrome

    2022  Volume 14, Issue 1, Page(s) 108

    Abstract: Background: We aimed to investigate changes of bile acids and resting energy expenditure (REE) in patients with type 2 diabetes mellitus (T2DM) after laparoscopic cholecystectomy (LC) and the role in metabolic homeostasis.: Methods: From December ... ...

    Abstract Background: We aimed to investigate changes of bile acids and resting energy expenditure (REE) in patients with type 2 diabetes mellitus (T2DM) after laparoscopic cholecystectomy (LC) and the role in metabolic homeostasis.
    Methods: From December 2019 to December 2021, a total of 77 T2DM patients with gallbladder polyps were included in our study. Among them, 40 patients who underwent LC were enrolled into the cholecystectomy group, and 37 patients who did not undergo LC were enrolled into the control group. Preoperative and 6-months postoperative demographic data, body weight, food intake, effects on diabetes control, and biomedical variables were recorded and compared.
    Results: The mean level of total bile acids (TBA) was higher than that in the control group (P = 0.033) and increased significantly after LC compared to baseline (P = 0.029). The REE level in the cholecystectomy group was higher than that in the control group (P = 0.032) and increased compared to the baseline (P = 0.011). The utilization of carbohydrates increased significantly after LC (P < 0.001) while the utilization of fat decreased (P < 0.001). The mean level of fasting plasma glucose (P = 0.004), hemoglobin A1C (P < 0.001), and homeostasis model assessment-insulin resistance (P = 0.045) decreased after LC. The mean level of total cholesterol (P = 0.003) and low-density lipoprotein cholesterol significantly decreased (P = 0.021), whereas the level of high-density lipoprotein cholesterol increased (P < 0.001).
    Conclusions: The level of REE and TBA increased after LC in patients with T2DM, and the glucose and lipid metabolism improved. Trial registration This study was registered in the Chinese Clinical Trial Registry on November 30, 2018, registered number: ChiCTR1900027823.
    Language English
    Publishing date 2022-07-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2518786-7
    ISSN 1758-5996
    ISSN 1758-5996
    DOI 10.1186/s13098-022-00880-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Observer-based control for nonlinear parameter-varying systems: A sum-of-squares approach.

    Zhu, Pingfang / Zeng, Jianping

    ISA transactions

    2020  Volume 111, Page(s) 121–131

    Abstract: This paper investigates the design problem of nonlinear and time-varying observer-based controllers for nonlinear parameter-varying systems without/with input constraints. With the aid of Lyapunov stability theory, the state-and-parameter-dependent ... ...

    Abstract This paper investigates the design problem of nonlinear and time-varying observer-based controllers for nonlinear parameter-varying systems without/with input constraints. With the aid of Lyapunov stability theory, the state-and-parameter-dependent linear matrix inequality conditions are obtained. These conditions are developed as convex programming problems. And a feasible solution can be obtained via sum-of-squares techniques. Thus, the commonly used backstepping/iterative methods are avoided. In addition, the effect of the bilinear product forms for the controller gain matrix and the Lyapunov functional are eliminated. A remarkable advantage of this proposed approach is that the state-and-parameter-dependent observer and the state-feedback controller can be designed independently, which significantly reduces the computational complexity. Finally, the feasibility and validity of the proposed method can be illustrated by simulation results.
    Language English
    Publishing date 2020-11-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012746-7
    ISSN 1879-2022 ; 0019-0578
    ISSN (online) 1879-2022
    ISSN 0019-0578
    DOI 10.1016/j.isatra.2020.11.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Sex-specific impact of mild obesity on the prognosis of ST-segment elevation myocardial infarction.

    Zhang, Lingling / Liu, Zhican / Zhu, Yunlong / Zeng, Jianping / Huang, Haobo / Yang, Wenbin / Peng, Ke / Wu, Mingxin

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 2228

    Abstract: This study aimed to clarify the existence of the mild obesity paradox in patients with ST-segment elevation myocardial infarction (STEMI) and assess the impact of mild obesity on the prognosis of STEMI. A retrospective cohort study was conducted on STEMI ...

    Abstract This study aimed to clarify the existence of the mild obesity paradox in patients with ST-segment elevation myocardial infarction (STEMI) and assess the impact of mild obesity on the prognosis of STEMI. A retrospective cohort study was conducted on STEMI patients who underwent percutaneous coronary intervention at Xiangtan Central Hospital from January 1, 2020 to July 31, 2022. After excluding individuals with a body mass index (BMI) of no less than 35 kg/m
    MeSH term(s) Humans ; Male ; Female ; ST Elevation Myocardial Infarction/complications ; Retrospective Studies ; Prognosis ; Obesity/complications ; Body Mass Index ; Percutaneous Coronary Intervention/adverse effects ; Treatment Outcome ; Risk Factors
    Language English
    Publishing date 2024-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-52515-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Clinical value of pulmonary congestion detection by lung ultrasound in patients with chronic heart failure.

    Li, Na / Zhu, Yunlong / Zeng, Jianping

    Clinical cardiology

    2021  Volume 44, Issue 11, Page(s) 1488–1496

    Abstract: Chronic heart failure is one of the common causes of hospitalization and death. Pulmonary congestion is the common disease feature of patients with chronic heart failure, which could be correctly diagnosed by lung ultrasound. Efficacy of lung ultrasound- ... ...

    Abstract Chronic heart failure is one of the common causes of hospitalization and death. Pulmonary congestion is the common disease feature of patients with chronic heart failure, which could be correctly diagnosed by lung ultrasound. Efficacy of lung ultrasound-guided pulmonary congestion management for patients with acute heart failure is well documented, however, more evidence is needed to establish the clinical value of pulmonary congestion detection by lung ultrasound examination in patients with chronic heart failure. This review summarized current evidence related to the use and clinical value of pulmonary congestion assessment by lung ultrasound in patients with chronic heart failure, aiming to provide new suggestions on promoting the widespread use of lung ultrasound in patients with chronic heart failure to improve the quality of life and outcome of patients with chronic heart failure.
    MeSH term(s) Heart Failure/diagnostic imaging ; Humans ; Lung/diagnostic imaging ; Prognosis ; Pulmonary Edema/diagnostic imaging ; Pulmonary Edema/etiology ; Quality of Life ; Ultrasonography
    Language English
    Publishing date 2021-10-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 391935-3
    ISSN 1932-8737 ; 0160-9289
    ISSN (online) 1932-8737
    ISSN 0160-9289
    DOI 10.1002/clc.23738
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  6. Article: Impact of chest pain center quality control indicators on mortality risk in ST-segment elevation myocardial infarction patients: a study based on Killip classification.

    Zhang, Lingling / Zeng, Jianping / Huang, Haobo / Zhu, Yunlong / Peng, Ke / Liu, Cai / Luo, Fei / Yang, Wenbin / Wu, Mingxin

    Frontiers in cardiovascular medicine

    2024  Volume 10, Page(s) 1243436

    Abstract: Background: Despite the crucial role of Chest pain centers (CPCs) in acute myocardial infarction (AMI) management, China's mortality rate for ST-segment elevation myocardial infarction (STEMI) has remained stagnant. This study evaluates the influence of ...

    Abstract Background: Despite the crucial role of Chest pain centers (CPCs) in acute myocardial infarction (AMI) management, China's mortality rate for ST-segment elevation myocardial infarction (STEMI) has remained stagnant. This study evaluates the influence of CPC quality control indicators on mortality risk in STEMI patients receiving primary percutaneous coronary intervention (PPCI) during the COVID-19 pandemic.
    Methods: A cohort of 664 consecutive STEMI patients undergoing PPCI from 2020 to 2022 was analyzed using Cox proportional hazards regression models. The cohort was stratified by Killip classification at admission (Class 1:
    Results: At a median follow-up of 17 months, 35 deaths were recorded. In Class ≥2, longer door-to-balloon (D-to-B) time, PCI informed consent time, catheterization laboratory activation time, and diagnosis-to-loading dose dual antiplatelet therapy (DAPT) time were associated with increased mortality risk. In Class 1, consultation time (notice to arrival) under 10 min reduced death risk. In Class ≥2, PCI informed consent time under 20 min decreased mortality risk.
    Conclusion: CPC quality control metrics affect STEMI mortality based on Killip class. Key factors include time indicators and standardization of CPC management. The study provides guidance for quality care during COVID-19.
    Language English
    Publishing date 2024-01-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1243436
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  7. Article: Becker muscular dystrophy with dilated cardiomyopathy: A case report.

    Chen, Yongliang / Zhu, Yunlong / Zhou, Yuying / Zeng, Jianping

    Clinical case reports

    2021  Volume 9, Issue 9, Page(s) e04777

    Abstract: Becker muscular dystrophy (BMD) complicated with DCM is rare in our daily clinical practice. BMD serves an etiology for heart failure patients due to DCM. Multidisciplinary management is required in this case. ...

    Abstract Becker muscular dystrophy (BMD) complicated with DCM is rare in our daily clinical practice. BMD serves an etiology for heart failure patients due to DCM. Multidisciplinary management is required in this case.
    Language English
    Publishing date 2021-09-18
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.4777
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  8. Article ; Online: Development and validation of a prognostic model for predicting post-discharge mortality risk in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI).

    Zhang, Lingling / Liu, Zhican / Zhu, Yunlong / Wu, Mingxin / Huang, Haobo / Yang, Wenbin / Peng, Ke / Zeng, Jianping

    Journal of cardiothoracic surgery

    2024  Volume 19, Issue 1, Page(s) 163

    Abstract: Background: Accurately predicting post-discharge mortality risk in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) remains a complex and critical challenge. The primary ... ...

    Abstract Background: Accurately predicting post-discharge mortality risk in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) remains a complex and critical challenge. The primary objective of this study was to develop and validate a robust risk prediction model to assess the 12-month and 24-month mortality risk in STEMI patients after hospital discharge.
    Methods: A retrospective study was conducted on 664 STEMI patients who underwent PPCI at Xiangtan Central Hospital Chest Pain Center between 2020 and 2022. The dataset was randomly divided into a training cohort (n = 464) and a validation cohort (n = 200) using a 7:3 ratio. The primary outcome was all-cause mortality following hospital discharge. The least absolute shrinkage and selection operator (LASSO) regression model was employed to identify the optimal predictive variables. Based on these variables, a regression model was constructed to determine the significant predictors of mortality. The performance of the model was evaluated using receiver operating characteristic (ROC) curve analysis and decision curve analysis (DCA).
    Results: The prognostic model was developed based on the LASSO regression results and further validated using the independent validation cohort. LASSO regression identified five important predictors: age, Killip classification, B-type natriuretic peptide precursor (NTpro-BNP), left ventricular ejection fraction (LVEF), and the usage of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers/angiotensin receptor-neprilysin inhibitors (ACEI/ARB/ARNI). The Harrell's concordance index (C-index) for the training and validation cohorts were 0.863 (95% CI: 0.792-0.934) and 0.888 (95% CI: 0.821-0.955), respectively. The area under the curve (AUC) for the training cohort at 12 months and 24 months was 0.785 (95% CI: 0.771-0.948) and 0.812 (95% CI: 0.772-0.940), respectively, while the corresponding values for the validation cohort were 0.864 (95% CI: 0.604-0.965) and 0.845 (95% CI: 0.705-0.951). These results confirm the stability and predictive accuracy of our model, demonstrating its reliable discriminative ability for post-discharge all-cause mortality risk. DCA analysis exhibited favorable net benefit of the nomogram.
    Conclusion: The developed nomogram shows potential as a tool for predicting post-discharge mortality in STEMI patients undergoing PPCI. However, its full utility awaits confirmation through broader external and temporal validation.
    MeSH term(s) Humans ; Prognosis ; ST Elevation Myocardial Infarction/surgery ; Patient Discharge ; Retrospective Studies ; Stroke Volume ; Angiotensin Receptor Antagonists ; Aftercare ; Ventricular Function, Left ; Angiotensin-Converting Enzyme Inhibitors ; Percutaneous Coronary Intervention/adverse effects ; Natriuretic Peptide, Brain
    Chemical Substances Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Natriuretic Peptide, Brain (114471-18-0)
    Language English
    Publishing date 2024-03-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2227224-0
    ISSN 1749-8090 ; 1749-8090
    ISSN (online) 1749-8090
    ISSN 1749-8090
    DOI 10.1186/s13019-024-02665-3
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  9. Article ; Online: Research Update on the Pathophysiological Mechanisms of Heart Failure with Preserved Ejection Fraction.

    Zhou, Yuying / Zhu, Yunlong / Zeng, Jianping

    Current molecular medicine

    2021  Volume 23, Issue 1, Page(s) 54–62

    Abstract: Heart failure (HF) is a serious clinical syndrome, usually occurs at the advanced stage of various cardiovascular diseases, featured by high mortality and rehospitalization rate. According to left ventricular (LV) ejection fraction (LVEF), HF has been ... ...

    Abstract Heart failure (HF) is a serious clinical syndrome, usually occurs at the advanced stage of various cardiovascular diseases, featured by high mortality and rehospitalization rate. According to left ventricular (LV) ejection fraction (LVEF), HF has been categorized as HF with reduced EF (HFrEF; LVEF<40%), HF with mid-range EF (HFmrEF; LVEF 40-49%), and HF with preserved EF (HFpEF; LVEF ≥50%). HFpEF accounts for about 50% of cases of heart failure and has become the dominant form of heart failure. The mortality of HFpEF is similar to that of HFrEF. There are no welldocumented treatment options that can reduce the morbidity and mortality of HFpEF now. Understanding the underlying pathological mechanisms is essential for the development of novel effective therapy options for HFpEF. In recent years, significant research progress has been achieved on the pathophysiological mechanism of HFpEF. This review aimed to update the research progress on the pathophysiological mechanism of HFpEF.
    MeSH term(s) Humans ; Heart Failure/therapy ; Stroke Volume
    Language English
    Publishing date 2021-11-29
    Publishing country Netherlands
    Document type Review ; Journal Article
    ZDB-ID 2064873-X
    ISSN 1875-5666 ; 1566-5240
    ISSN (online) 1875-5666
    ISSN 1566-5240
    DOI 10.2174/1566524021666211129111202
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  10. Article ; Online: Fixed-time consensus control for multi-agent systems with prescribed performance under matched and mismatched disturbances.

    Ke, Jin / Huang, Wenchao / Wang, Jingyao / Zeng, Jianping

    ISA transactions

    2021  Volume 119, Page(s) 135–151

    Abstract: The consensus problem is considered for multi-agent systems with disturbances. Three fixed-time prescribed performance methods are proposed to satisfy the transient performance and steady-state performance of multi-agent systems consensus. If the multi- ... ...

    Abstract The consensus problem is considered for multi-agent systems with disturbances. Three fixed-time prescribed performance methods are proposed to satisfy the transient performance and steady-state performance of multi-agent systems consensus. If the multi-agent systems are affected by matched disturbances, the consensus tracking errors constraints are guaranteed at first. Next, the consensus tracking errors constraints and their change rates constraints are further considered. Moreover, with the help of a fixed-time observer, the consensus tracking errors constraints result is expended to the case of multi-agent systems affected by mismatched disturbances. The proposed methods can provide the satisfactory system performances, including that consensus tracking errors always evolve within predefined bounds, converge to a small closed region containing zero in fixed time and then converge to zero asymptotically. Simulations are provided to verify the effectiveness of the proposed methods.
    Language English
    Publishing date 2021-02-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012746-7
    ISSN 1879-2022 ; 0019-0578
    ISSN (online) 1879-2022
    ISSN 0019-0578
    DOI 10.1016/j.isatra.2021.02.032
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