Article ; Online: Combined toxicity and adverse outcome pathways of common pesticides on
Environmental science. Processes & impacts
2024 Volume 26, Issue 3, Page(s) 611–621
Abstract: Pesticides due to their extensive use have entered the soil and water environment through various pathways, causing great harm to the environment. Herbicides and insecticides are common pesticides with long-term biological toxicity and bioaccumulation, ... ...
Abstract | Pesticides due to their extensive use have entered the soil and water environment through various pathways, causing great harm to the environment. Herbicides and insecticides are common pesticides with long-term biological toxicity and bioaccumulation, which can harm the human body. The concept of the adverse outcome pathway (AOP) involves systematically analyzing the response levels of chemical mixtures to health-related indicators at the molecular and cellular levels. The AOP correlates the structures of chemical pollutants, toxic molecular initiation events and adverse outcomes of biological toxicity, providing a new model for toxicity testing, prediction, and evaluation of pollutants. Therefore, typical pesticides including diquat (DIQ), cyanazine (CYA), dipterex (DIP), propoxur (PRO), and oxamyl (OXA) were selected as research objects to explore the combined toxicity of typical pesticides on |
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MeSH term(s) | Humans ; Pesticides/toxicity ; Chlorella ; Adverse Outcome Pathways ; Insecticides ; Propoxur/pharmacology ; Environmental Pollutants ; Water Pollutants, Chemical/pharmacology |
Chemical Substances | Pesticides ; Insecticides ; Propoxur (BFH029TL73) ; Environmental Pollutants ; Water Pollutants, Chemical |
Language | English |
Publishing date | 2024-03-20 |
Publishing country | England |
Document type | Journal Article |
ZDB-ID | 2703814-2 |
ISSN | 2050-7895 ; 2050-7887 |
ISSN (online) | 2050-7895 |
ISSN | 2050-7887 |
DOI | 10.1039/d3em00525a |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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