Article ; Online: Effect and longevity of botulinum toxin in the treatment of gummy smile: a meta-analysis and meta-regression.
2021 Volume 26, Issue 1, Page(s) 109–117
Abstract: Objective: The aim of this systematic review is to synthesize the evidence on the effectiveness and longevity of the botulinum toxin in the treatment of individuals with excessive gingival exposure.: Methods: The search was adapted to six electronic ... ...
| Abstract | Objective: The aim of this systematic review is to synthesize the evidence on the effectiveness and longevity of the botulinum toxin in the treatment of individuals with excessive gingival exposure. Methods: The search was adapted to six electronic databases and gray literature. The risk of bias was assessed using the Cochrane Risk of Bias Assessment Tool for Non-Randomized and Randomized Studies of Interventions. Meta-analyses and meta-regression were performed using random effects models. Results: A total of 5247 articles were collected during the final search in the database, resulting in 17 articles included. There was a mean decrease of 3.42 mm [95% CI = -4.50 to -2.34; I Conclusion: Botulinum toxin is an alternative technique considered effective for reducing gummy smile, especially for gummy smiles up to 4 mm, with a longevity of at least 12 weeks, returning close to initial values within 24 weeks after application. Clinical relevance: The knowledge about the longevity and effectiveness of botulinum toxin in the treatment of gummy smile allows for a more adequate clinical planning for these cases, as well as for clinical decisions, as for prognostic factors. |
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| MeSH term(s) | Botulinum Toxins, Type A ; Esthetics, Dental ; Gingiva ; Humans ; Smiling | |||||
| Chemical Substances | Botulinum Toxins, Type A (EC 3.4.24.69) | |||||
| Language | English | |||||
| Publishing date | 2021-10-15 | |||||
| Publishing country | Germany | |||||
| Document type | Journal Article ; Meta-Analysis ; Review ; Systematic Review | |||||
| ZDB-ID | 1364490-7 | |||||
| ISSN | 1436-3771 ; 1432-6981 | |||||
| ISSN (online) | 1436-3771 | |||||
| ISSN | 1432-6981 | |||||
| DOI | 10.1007/s00784-021-04223-w | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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