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  1. Book ; Online: Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft

    Fehse, Boris / Schickl, Hannah / Bartfeld, Sina / Zenke, Martin

    AG Gentechnologiebericht mit freundlicher Unterstützung der DG-GT und des GSCN

    2023  

    Author's details herausgegeben von Boris Fehse, Hannah Schickl, Sina Bartfeld, Martin Zenke
    Keywords Biology/Technique ; Genetics
    Language German
    Size 1 Online-Ressource (XXIX, 337 S)
    Edition 1st ed. 2024
    Publisher Springer Berlin Heidelberg ; Imprint: Springer
    Publishing place Berlin, Heidelberg
    Document type Book ; Online
    HBZ-ID HT030624140
    ISBN 978-3-662-67908-1 ; 9783662679074 ; 3-662-67908-6 ; 3662679078
    DOI 10.1007/978-3-662-67908-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Stammzellforschung

    Marx-Stölting, Lilian / Zenke, Martin / Schickl, Hannah

    2018  

    Abstract: Patients have high expectations of stem cells in the treatment of severe and devastating diseases that have no effective therapy at the moment. But what are stem cells? How far has stem cell research progressed internationally and, in particular, in ... ...

    Abstract Patients have high expectations of stem cells in the treatment of severe and devastating diseases that have no effective therapy at the moment. But what are stem cells? How far has stem cell research progressed internationally and, in particular, in Germany? And what is allowed or prohibited according to German law compared to other countries?This book by the interdisciplinary research group called "Gene Technology Report" at the Berlin-Brandenburg Academy of Sciences and Humanities presents the current state of stem cell research and discusses ethical, legal and economic issues as well as how to apply research findings in medicine. Additionally, it uses so-called indicators to quantify and describe new developments in the stem cell field.With contributions byMartin Zenke, Lilian Marx-Stölting, Hannah Schickl, Sabine Könninger, Moritz Mall, Marius Wernig, Johannes Jungverdorben, Andreas Till, Oliver Brüstle, Guangming Wu, Lei Lei, Hans R. Schöler, Silvia Basilico, Berthold Göttgens, Sina Bartfeld, Hans Clevers, Boris Fehse, Peter Löser, Anke Guhr, Sabine Kobold, Andrea Seiler Wulczyn, Daniel Besser, Ira Herrmann, Martin Heyer, Vasilija Rolfes, Uta Bittner, Heiner Fangerau, Christine Hauskeller, Clara Hick, Sara Gerke, Jochen Taupitz, Joseph Straus, Kathrin Hunze
    Keywords Sociology (General)
    Size 1 electronic resource ( p.)
    Publisher Nomos Verlagsgesellschaft mbH & Co. KG
    Document type Book ; Online
    Note de ; Open Access
    HBZ-ID HT020102622
    ISBN 9783845287720 ; 3845287721
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: Stammzellforschung

    Zenke, Martin / Marx-Stölting, Lilian / Schickl, Hannah

    Aktuelle wissenschaftliche und gesellschaftliche Entwicklungen

    2018  

    Abstract: Patienten und Patientinnen setzen große Hoffnungen in Stammzellen zur Behandlung von schwersten und bisher nicht oder nur ungenügend therapierbaren Erkrankungen. -- Was aber sind Stammzellen? Wo steht die Stammzellforschung international und mit Blick ... ...

    Abstract Patienten und Patientinnen setzen große Hoffnungen in Stammzellen zur Behandlung von schwersten und bisher nicht oder nur ungenügend therapierbaren Erkrankungen. -- Was aber sind Stammzellen? Wo steht die Stammzellforschung international und mit Blick auf Deutschland heute? Was ist in Deutschland im internationalen Vergleich erlaubt? -- Der Sammelband der Interdisziplinären Arbeitsgruppe Gentechnologiebericht der Berlin-Brandenburgischen Akademie der Wissenschaften stellt den aktuellen Sachs...
    Keywords Sammelwerk ; HPHP025 ; NBIA023 ; HPHP020 ; MHMA015 ; LLWOG40 ; HPHP030 ; MHMA035 ; Lebendswissenschaft ; Zellbiologie ; Medizinethik ; BBAW ; DNA ; Bioethik ; Stammzellen ; Stammzellforschung ; embryonale Stammzellen ; ES-Zellen
    Language German
    Size 329 p.
    Edition 1
    Publisher Nomos
    Document type Book
    Note Ernährungs-, Umwelt- und Agrarwissenschaften 250418
    Format 153 x 227
    ISBN 9783848746064 ; 3848746069
    Database PDA

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  4. Book: Stammzellforschung

    Zenke, Martin / Marx-Stölting, Lilian / Schickl, Hannah

    aktuelle wissenschaftliche und gesellschaftliche Entwicklungen

    (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften ; Band 39)

    2018  

    Author's details herausgegeben von Martin Zenke, Lilian Marx-Stölting, Hannah Schickl
    Series title Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften ; Band 39
    Interdisziplinäre Arbeitsgruppen, Forschungsberichte / Berlin-Brandenburgische Akademie der Wissenschaften
    Collection Interdisziplinäre Arbeitsgruppen, Forschungsberichte / Berlin-Brandenburgische Akademie der Wissenschaften
    Keywords Stammzelle ; Forschung
    Subject Wissenschaftliche Forschung ; Forschungen ; Stem cell
    Language German
    Size 329 Seiten, Diagramme, Karten
    Edition 1. Auflage
    Publisher Nomos
    Publishing place Baden-Baden
    Publishing country Germany
    Document type Book
    HBZ-ID HT019642502
    ISBN 978-3-8487-4606-4 ; 9783845287720 ; 3-8487-4606-9 ; 3845287721
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2018 A 1381 available for loan (reading room) Lesesaal EG

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  5. Book ; Online: Stammzellforschung

    Zenke, Martin / Marx-Stölting, Lilian / Schickl, Hannah

    aktuelle wissenschaftliche und gesellschaftliche Entwicklungen

    (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften ; Band 39)

    2018  

    Author's details herausgegeben von Martin Zenke, Lilian Marx-Stölting, Hannah Schickl
    Series title Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften ; Band 39
    Interdisziplinäre Arbeitsgruppen, Forschungsberichte / Berlin-Brandenburgische Akademie der Wissenschaften
    Collection Interdisziplinäre Arbeitsgruppen, Forschungsberichte / Berlin-Brandenburgische Akademie der Wissenschaften
    Keywords Lebendswissenschaft ; Zellbiologie ; Medizinethik ; BBAW ; DNA ; Bioethik ; Stammzellen ; Stammzellforschung ; embryonale Stammzellen ; ES-Zellen ; Stammzelle ; Forschung
    Subject Wissenschaftliche Forschung ; Forschungen ; Stem cell
    Language German
    Size 1 Online-Ressource (336 Seiten), Illustrationen
    Edition 1. Auflage
    Publisher Nomos
    Publishing place Baden-Baden
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT019613801
    ISBN 978-3-8452-8772-0 ; 9783848746064 ; 3-8452-8772-1 ; 3848746069
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  6. Book ; Thesis: Assessing the dendritic cell differentiation potential of amplified mouse and human hematopoietic stem cells after transplantation into the NOD-(scid)-IL2Rγ-/- mouse model

    Esser, Mathias / Zenke, Martin / Rübben, Albert

    2015  

    Author's details vorgelegt von Mathias Esser aus Duisburg ; Berichter: Herr Universitätsprofessor Dr. rer. nat. Martin Zenke, Herr Professor Dr. med. Albert Rübben
    Language English
    Size VII, 125 Seiten, Illustrationen, Diagramme
    Publishing place Aachen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, RWTH Aachen, 2015
    Note Zusammenfassung in deutscher und englischer Sprache
    HBZ-ID HT018873775
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2016 D 780 order for loan Magazin

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  7. Book ; Online: Stammzellforschung

    Marx-Stölting, Lilian / Schickl, Hannah / Zenke, Martin

    aktuelle wissenschaftliche und gesellschaftliche Entwicklungen : Kurzfassung = Stem cell research : current scientific and societal developments : summary

    2017  

    Title variant Stem cell research
    Institution Berlin-Brandenburgische Akademie der Wissenschaften / Interdisziplinäre Arbeitsgruppe Gentechnologiebericht
    Author's details Berlin-Brandenburgische Akademie der Wissenschaften, Interdisziplinäre Arbeitsgruppe Gentechnologiebericht (Hrsg.) ; Konzeption Concept: Lilian Marx-Stölting, Hannah Schickl, Martin Zenke
    Keywords Stammzellforschung ; Stem Cell Research ; Gene Technology ; iPS-Zellen
    Subject code 610
    Language German ; English
    Size 1 Online-Ressource (64 Seiten), Diagramme
    Publisher Berlin-Brandenburgische Akademie der Wissenschaften
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT021307869
    ISBN 9783939818762 ; 3939818763
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  8. Article ; Online: Human ES cell-derived dendritic cells: Meeting the challenge of immune rejection in allogeneic cell therapy.

    Zenke, Martin

    EBioMedicine

    2020  Volume 62, Page(s) 103144

    MeSH term(s) Allografts ; Animals ; Cell- and Tissue-Based Therapy/adverse effects ; Cell- and Tissue-Based Therapy/methods ; Dendritic Cells/cytology ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Embryonic Stem Cells/cytology ; Embryonic Stem Cells/metabolism ; Graft Rejection/immunology ; Graft Rejection/prevention & control ; Humans
    Language English
    Publishing date 2020-11-27
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2851331-9
    ISSN 2352-3964
    ISSN (online) 2352-3964
    DOI 10.1016/j.ebiom.2020.103144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7090: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Dendritic cells generated from induced pluripotent stem cells and by direct reprogramming of somatic cells.

    Flosdorf, Niclas / Zenke, Martin

    European journal of immunology

    2022  Volume 52, Issue 12, Page(s) 1880–1888

    Abstract: Novel and exciting avenues allow generating dendritic cells (DC) by reprogramming of somatic cells. DC are obtained from induced pluripotent stem cells (iPS cells), referred to as ipDC, and by direct reprogramming of cells toward DC, referred to as ... ...

    Abstract Novel and exciting avenues allow generating dendritic cells (DC) by reprogramming of somatic cells. DC are obtained from induced pluripotent stem cells (iPS cells), referred to as ipDC, and by direct reprogramming of cells toward DC, referred to as induced DC (iDC). iPS cells represent pluripotent stem cells generated by reprogramming of somatic cells and can differentiate into all cell types of the body, including DC. This makes iPS cells and ipDC derived thereof useful for studying various DC subsets, acquiring high cell numbers for research and clinical use, or applying genome editing to generate DC with wanted properties. Thereby, ipDC overcome limitations in specific DC subsets, which are only found in low abundance in blood or lymphoid organs. iDC are generated by direct reprogramming of somatic cells with a specific set of transcription factors and offer an avenue to obtain DC without a pluripotent cell intermediate. ipDC and iDC retain patient and disease-specific mutations and this opens new perspectives for studying DC in disease. This review summarizes the current techniques used to generate ipDC and iDC, and the types and functionality of the DC generated.
    MeSH term(s) Humans ; Induced Pluripotent Stem Cells ; Dendritic Cells
    Language English
    Publishing date 2022-09-14
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 120108-6
    ISSN 1521-4141 ; 0014-2980
    ISSN (online) 1521-4141
    ISSN 0014-2980
    DOI 10.1002/eji.202149550
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 489: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MG 85: Show issues

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  10. Book ; Online: Fünfter Gentechnologiebericht : Sachstand und Perspektiven für Forschung und Anwendung

    Fehse, Boris / Hucho, Ferdinand / Bartfeld, Sina / Clemens, Stephan / Erb, Tobias / Fangerau, Heiner / Hampel, Jürgen / Korte, Martin / Marx-Stölting, Lilian / Mundlos, Stefan / Osterheider, Angela / Pichl, Anja / Reich, Jens / Schickl, Hannah / Schicktanz, Silke / Taupitz, Jochen / Walte, Jörn / Winkler, Eva / Zenke, Martin

    2021  

    Keywords MBP, KCQ, JFMG ; Biologie Ethik Forschung Gene Gesundheit Medizin Gentechnologie Grüne Gentechnik Synthetische Biologie Epigenetik Einzelzellanalyse Gene Drives Organoide Stammzellforschung Hirnorganoide Embryoide Datenschutz Monitoring Genbegriff Genom Gendeterminismus
    Size 1 electronic resource (592 pages)
    Publishing place Baden-Baden
    Document type Book ; Online
    Note German ; Open Access
    HBZ-ID HT021229742
    ISBN 978-3-7489-2724-2 ; 3-7489-2724-X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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