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  1. Article: How to control air pollution with economic means? Exploration of China's green finance policy

    Zhang, Ailian / Wang, Shuyao / Liu, Bai

    Journal of cleaner production. 2022 June 15, v. 353

    2022  

    Abstract: Air pollution is not only an environmental problem, but also an economic problem. Faced with the deteriorating air pollution, the role of financial institutions is increasingly valued. Because different air pollutants come from diverse sources, the same ... ...

    Abstract Air pollution is not only an environmental problem, but also an economic problem. Faced with the deteriorating air pollution, the role of financial institutions is increasingly valued. Because different air pollutants come from diverse sources, the same economic means have different impacts. To investigate this question, this paper adopts difference-in-differences to test China's green finance policy issued in 2017. The results indicate that green finance policy is capable of controlling overall situation of air pollution. As for the specific six pollutants, it shows superiority in reducing SO₂, NO₂ and PM₂.₅, but inferiority in reducing CO, O₃ and PM₁₀. Besides, the control effects of green finance policy are through local companies' economic behaviors. Compared with the economically developed regions, the emission reduction effects of green finance policy in the economically underdeveloped regions are better. These findings offer references for how to control air pollution with economic means from the perspective of micro practice.
    Keywords air ; air pollution ; economic policy ; China
    Language English
    Dates of publication 2022-0615
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 0959-6526
    DOI 10.1016/j.jclepro.2022.131664
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: "Smart Process" of Medical Innovation: The Synergism Based on Network and Physical Space.

    Zhang, Ailian / Pan, Mengmeng

    International journal of environmental research and public health

    2020  Volume 17, Issue 11

    Abstract: Medical innovation has a profound impact on public health, and it is always of social concern to encourage innovation and enhance the value in health care delivery. Based on a sample of China's listed firms in the medical industry from 2007 to 2018, this ...

    Abstract Medical innovation has a profound impact on public health, and it is always of social concern to encourage innovation and enhance the value in health care delivery. Based on a sample of China's listed firms in the medical industry from 2007 to 2018, this paper highlights the independent and mixed roles of informatization and high-speed rail in public medical innovation. The results show that informatization at network space and high-speed rail at physical space effectively promote the innovation of medical enterprises. In addition, "online" information technology and "offline" high-speed rail technology have a synergistic effect on medical innovation, especially in areas with a low level of innovation. The conclusion supports the positive significance of technology in the application of public health and proposes that the construction of smart society is very important to public health.
    MeSH term(s) Biomedical Technology/trends ; China ; Health Care Sector ; Inventions ; Public Health ; Railroads/classification ; Technology
    Language English
    Publishing date 2020-05-27
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph17113798
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Near-infrared spectroscopy combined with machine learning for rapid identification of Atractylodis rhizoma decoction pieces

    Jiang, Zhiwei / Jin, Ke / Zhong, Lingjiao / Zheng, Ying / Shao, Qingsong / Zhang, Ailian

    Industrial Crops & Products. 2023 July, v. 197 p.116579-

    2023  

    Abstract: As a naturally occurring plant source of essential oil, Atractylodis rhizoma (AR) is of significant economic and therapeutic importance. In modern medical use, it is preferable to process the material into flakes of dried AR. Fake products often pass off ...

    Abstract As a naturally occurring plant source of essential oil, Atractylodis rhizoma (AR) is of significant economic and therapeutic importance. In modern medical use, it is preferable to process the material into flakes of dried AR. Fake products often pass off as authentic AR, and products from non-primary production areas pass off as primary production areas to pursue high profits. In this study, near-infrared spectroscopy (NIRS) was developed to better identify the authenticity, botanical sources, and geographical origins of AR. The impacts of pretreatment, selection of characteristic wavenumbers, and parameter optimization on model performance were compared and analyzed. Five different types of machine learning methods were used. The results showed that the extreme learning machine (ELM) had the best effect in identifying the authenticity of AR, while the back propagation neural network (BPNN) had advantages in determining the sources of plants. The support vector classification (SVC) had great potential to pinpoint the geographical origins of Atractylodes lancea (Thunb.) DC. and Atractylodes chinensis (DC.) Koidz. The feasibility of direct spectral acquisition without crushing the sample was also demonstrated. Therefore, NIRS combined with machine learning is a fast, effective, and feasible method to identify the authenticity, botanical sources, and geographical origins of AR.
    Keywords Atractylodes lancea ; essential oils ; model validation ; near-infrared spectroscopy ; primary productivity ; rhizomes ; therapeutics ; Atractylodis rhizoma ; Identification ; Qualitative models ; Machine learning
    Language English
    Dates of publication 2023-07
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 1132158-1
    ISSN 1872-633X ; 0926-6690
    ISSN (online) 1872-633X
    ISSN 0926-6690
    DOI 10.1016/j.indcrop.2023.116579
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Corrigendum to "Improving adjuvanticity of crude polysaccharides from cultivated Artemisia rupestris L. for influenza vaccine by promoting long-term immunity and TH1/TH2 response with dose-sparing effect" [J. Ethnopharmacol. 294 (2022) 115350].

    Li, Quanxiao / Weng, Xiang / Xiao, Peng / Yang, Yu / Zhang, Ailian

    Journal of ethnopharmacology

    2022  Volume 298, Page(s) 115666

    Language English
    Publishing date 2022-08-27
    Publishing country Ireland
    Document type Published Erratum
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2022.115666
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Chemical composition and adjuvant properties of the macromolecules from cultivated Cistanche deserticola Y. C. Ma as an immunopotentiator.

    Weng, Xiang / Zhao, Bing / Feng, Shuangshuang / Yang, Yu / Zhang, Ailian

    International journal of biological macromolecules

    2022  Volume 220, Page(s) 638–658

    Abstract: The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola). Two macromolecules designated as CCDP-1 (26.5 kDa) and CCDP-2 (32.3 kDa) from ... ...

    Abstract The study aims to investigate the constituents, adjuvant effects, and underlying mechanisms of purified polysaccharides from cultivated Cistanche deserticola (C. deserticola). Two macromolecules designated as CCDP-1 (26.5 kDa) and CCDP-2 (32.3 kDa) from C. deserticola were respectively identified as carbohydrate-lignin complexes with 44.1 % and 43.8 % lignin. CCDP-1 and CCDP-2 were composed of glucose, rhamnose, galactose, arabinose, and mannose respectively in the molar ratios of 7.22: 5.98:2.51:1.81:1.00 and 6.57:8.48:4.20:2.72:1.00. An in vitro experiment revealed that endotoxin-free CCDP-1 and CCDP-2 promoted splenocyte proliferation without cytotoxicity, but CCDP-2 induced dendritic cell (DC) maturation more efficiently than CCDP-1. An in vivo experiment suggested that CCDP-2 enhanced OVA-specific antibody production, antigen-specific T-cell activation, IFN-γ production, IL-4 production, and DC activation. Notably, CCDP-2 elicited a Th1-biased response. Mechanically, CCDP-2 upregulated CD40, CD80, CD86, and MHC II, facilitated allogeneic T-cell proliferation and Th1/Th2 cytokines, improved IFN-γ, IL-12, IL-6, and TNF-α production, and decreased endocytosis from DCs in vitro. Blocking assays indicated that TLR2 and TLR4 were the membrane receptor candidates of DCs. Western blot implied that CCDP-2 with the immune-enhancing activities were involved in the activation of MAPKs and NF-κB pathways in a dose-/time-related manner and could be employed as a more balanced Th1/Th2 adjuvant for vaccine exploitation.
    MeSH term(s) Adjuvants, Immunologic/metabolism ; Adjuvants, Immunologic/pharmacology ; Arabinose/pharmacology ; Cistanche/chemistry ; Cytokines/metabolism ; Dendritic Cells ; Galactose/metabolism ; Glucose/metabolism ; Interleukin-12/metabolism ; Interleukin-4/metabolism ; Interleukin-6/metabolism ; Lignin/metabolism ; Mannose/metabolism ; NF-kappa B/metabolism ; Polysaccharides/chemistry ; Rhamnose/metabolism ; Toll-Like Receptor 2/metabolism ; Toll-Like Receptor 4/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Vaccines/pharmacology
    Chemical Substances Adjuvants, Immunologic ; Cytokines ; Interleukin-6 ; NF-kappa B ; Polysaccharides ; Toll-Like Receptor 2 ; Toll-Like Receptor 4 ; Tumor Necrosis Factor-alpha ; Vaccines ; Interleukin-12 (187348-17-0) ; Interleukin-4 (207137-56-2) ; Lignin (9005-53-2) ; Arabinose (B40ROO395Z) ; Glucose (IY9XDZ35W2) ; Mannose (PHA4727WTP) ; Rhamnose (QN34XC755A) ; Galactose (X2RN3Q8DNE)
    Language English
    Publishing date 2022-08-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2022.08.072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cultivated Artemisia rupestris L. polysaccharide CARP2 as an adjuvant for influenza vaccines to prolong immune responses.

    Weng, Xiang / Zhao, Bing / Li, Rang / Li, Quanxiao / Zhang, Ailian

    International journal of biological macromolecules

    2022  

    Abstract: In the study, the adjuvant features of the immunoregulatory polysaccharide component CARP2 isolated from cultivated Artemisia rupestris L. for influenza virus vaccine (IVV) and the mechanism responsible for its action in DCs were further explored. CARP2 ... ...

    Abstract In the study, the adjuvant features of the immunoregulatory polysaccharide component CARP2 isolated from cultivated Artemisia rupestris L. for influenza virus vaccine (IVV) and the mechanism responsible for its action in DCs were further explored. CARP2 showed a typical absorbance peak of polysaccharides in spectral analysis. At two doses of CARP2-adjuvanted IVV, IgG, hemagglutination inhibition (HI) titers, and effector/memory T cells were generated and lasted for 275 days without adverse events. CARP2 primed rapid HI and IgG, IgG2a/IgG1 ratio, splenocyte proliferation, and cytotoxic T lymphocyte (CTL), and facilitated the generation of INF-γ and IL-4 by activating DCs and regulatory T cells (Tregs). Additionally, CARP2 achieved the ten-fold dose-sparing effect. In vitro, CARP2 stimulated DCs to prime the production of Th1/Th2 cytokines and CCR7 and activated MyD88-dependent pathway by upregulating the expressions of TLR4, MyD88, TRAF-6, and p65. In contrast, MyD88, TRAF-6, and NF-κB inhibitors partially blocked the effect through reducing related cytokines and proteins. Overall, CARP2 promoted IVV efficacy, which was involved in the modulation of Th1/Th2 responses and shifted toward Th1-polarizing response via TLR4/MyD88/TRAF/NF-κB activation in DCs.
    Language English
    Publishing date 2022-10-21
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2022.10.159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Improving adjuvanticity of crude polysaccharides from cultivated Artemisia rupestris L. for influenza vaccine by promoting long-term immunity and T

    Li, Quanxiao / Weng, Xiang / Xiao, Peng / Yang, Yu / Zhang, Ailian

    Journal of ethnopharmacology

    2022  Volume 294, Page(s) 115350

    Abstract: Ethnopharmacological relevance: Influenza virus vaccines (IVV) with balanced T: Aim of study: The study aims to determine the efficacy and safety of crude polysaccharides from cultivated Artemisia rupestris L. (CPCAR) as an adjuvant for IVV.: ... ...

    Abstract Ethnopharmacological relevance: Influenza virus vaccines (IVV) with balanced T
    Aim of study: The study aims to determine the efficacy and safety of crude polysaccharides from cultivated Artemisia rupestris L. (CPCAR) as an adjuvant for IVV.
    Materials and methods: CPCAR was prepared with hot extraction and ethanol precipitation method and primary physico-chemical characters were tested. Mice were vaccinated by subcutaneous route with IVV formulated with different dose of CPCAR to detecting the elicited T
    Results: IVV formulated with CPCAR without LPS contamination could augment balanced T
    Conclusions: Collectively, the study demonstrated the potential of CPCAR as an aqueous polysaccharide adjuvant for IVV to induce rapid and balanced T
    MeSH term(s) Adjuvants, Immunologic/pharmacology ; Animals ; Artemisia ; Immunoglobulin G ; Influenza Vaccines ; Mice ; Mice, Inbred BALB C ; Polysaccharides/pharmacology ; Th1 Cells
    Chemical Substances Adjuvants, Immunologic ; Immunoglobulin G ; Influenza Vaccines ; Polysaccharides
    Language English
    Publishing date 2022-05-06
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2022.115350
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Immunoregulatory properties of the cultivated Artemisia rupestris L. polysaccharide as a potential adjuvant.

    Li, Quanxiao / Weng, Xiang / Zhao, Bing / Yang, Yu / Zhang, Ailian

    Carbohydrate polymers

    2022  Volume 291, Page(s) 119525

    Abstract: Two components (CARP-1 and CARP-2) were fractionated from cultivated Artemisia rupestris L. and then characterized by HPGPC and HPLC. CARP-1 with a molecular weight of 2.72 × ... ...

    Abstract Two components (CARP-1 and CARP-2) were fractionated from cultivated Artemisia rupestris L. and then characterized by HPGPC and HPLC. CARP-1 with a molecular weight of 2.72 × 10
    MeSH term(s) Adjuvants, Immunologic/pharmacology ; Animals ; Artemisia ; Mice ; NF-kappa B ; Polysaccharides/pharmacology ; Tumor Necrosis Factor-alpha
    Chemical Substances Adjuvants, Immunologic ; NF-kappa B ; Polysaccharides ; Tumor Necrosis Factor-alpha
    Language English
    Publishing date 2022-04-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1501516-6
    ISSN 1879-1344 ; 0144-8617
    ISSN (online) 1879-1344
    ISSN 0144-8617
    DOI 10.1016/j.carbpol.2022.119525
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Corrigendum: Preparation and biological evaluation of a novel agarose-grafting-hyaluronan scaffold for accelerated wound regeneration (2020

    Chu, Bin / Zhang, Ailian / Huang, Jianyan / Peng, Xiaohui / You, Lingling / Wu, Chaoxi / Tang, Shunqing

    Biomedical materials (Bristol, England)

    2023  Volume 18, Issue 6

    Language English
    Publishing date 2023-09-12
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2265222-X
    ISSN 1748-605X ; 1748-6041
    ISSN (online) 1748-605X
    ISSN 1748-6041
    DOI 10.1088/1748-605X/acf2d6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Heterogeneous impact of CO₂ emissions on renewable energy technology innovation between oil importers and exporters

    Liu, Bai / Liu, Yutian / Zhang, Ailian

    Energy & environment. 2021 Mar., v. 32, no. 2

    2021  

    Abstract: With the depletion of fossil energy and the rise of global temperature, it is urgent to use renewable energy to solve environmental problems. By studying the heterogeneous relationship between CO₂ emissions and renewable energy technology innovation in ... ...

    Abstract With the depletion of fossil energy and the rise of global temperature, it is urgent to use renewable energy to solve environmental problems. By studying the heterogeneous relationship between CO₂ emissions and renewable energy technology innovation in different countries, we can find out the gap and something helpful to energy development. In the empirical test, we use the negative binomial regression model with fixed effects to study the impact of CO₂ emissions on renewable energy technology innovation from 1997 to 2016. The research shows that impact is positive in oil-importing countries, but this relationship is not established in oil-exporting countries. In both oil importers and oil exporters, CO₂ emissions have a positive effect on the solar energy technological innovation, however, the influence on the technology innovation of solar energy in oil exporters is more significant than that of renewable energy. Whether for oil importers or oil exporters, it can be more reasonable and effective to develop renewable energy by clarifying the impact of CO₂ emissions on domestic renewable energy technology innovation.
    Keywords carbon dioxide ; energy ; environment ; fossil fuels ; oils ; regression analysis ; solar energy ; technology ; temperature
    Language English
    Dates of publication 2021-03
    Size p. 281-294.
    Publishing place SAGE Publications
    Document type Article
    ZDB-ID 1033480-4
    ISSN 2048-4070 ; 0958-305X
    ISSN (online) 2048-4070
    ISSN 0958-305X
    DOI 10.1177/0958305X20928934
    Database NAL-Catalogue (AGRICOLA)

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