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Article ; Online: Discovery of resident memory T cells in inflammatory vitiligo: A case report.

Xu, YanLi / Zhang, Bao-Xiang / Lin, Mao / Zhang, Lu

2022 Volume 101, Issue 41, Page(s) e31007

Abstract: Rationale: The purpose of this report was to describe resident memory cluster of differentiation 8 (CD8) + T cells may contribute to the progression of inflammatory vitiligo.: Patient concerns: A 32-year-old male has a stable vitiligo for 1 year, ... ...

Abstract	Rationale: The purpose of this report was to describe resident memory cluster of differentiation 8 (CD8) + T cells may contribute to the progression of inflammatory vitiligo. Patient concerns: A 32-year-old male has a stable vitiligo for 1 year, then some patches present inflammatory erythema. Two years later, the inflammatory patches enlarged and joined together, and the remaining 2 common patches shows repigmentation and no change respectively. Both CD69 + CD8 + T cells and CD103 + CD8 + T cells showed marked increase in inflammatory vitiligo than common vitiligo. Diagnosis: Histological findings show that the numbers of lymphocytes are increased in inflammatory vitiligo than common vitiligo. Immunofluorescence staining show that the numbers of CD69 + CD8 + T cells demonstrated a marked increase in inflammatory vitiligo than common vitiligo. Interventions: Without any intervention. Outcomes: The previous upper 2 patches on the abdomen with erythematous rim were enlarged and joined together. However the lowest lesion with uninflamed common rim on the abdomen remained static, the one on the right groin showed spot-like repigmentation. Lessons: This case report demonstrates that resident memory CD8 + T cells may contribute to the progression of inflammatory vitiligo.
MeSH term(s)	Adult ; CD8-Positive T-Lymphocytes/pathology ; Erythema ; Humans ; Hypopigmentation ; Male ; Memory T Cells ; Vitiligo
Language	English
Publishing date	2022-09-26
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000031007
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Ua VI Zs.171: Show issues

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Article ; Online: Tanshinone IIA alleviates vitiligo by suppressing AKT mediated CD8

Zhang, Diancai / Wang, Yujie / Li, Guangzhi / Zhang, Baoxiang

Dermatologic therapy

2021 Volume 34, Issue 5, Page(s) e15086

Abstract: Tanshinone IIA has been reported to exhibit anti-inflammatory effects, while it is not clear whether Tanshinone IIA has protective role in vitiligo. Premelanosome (PMEL) ... ...

Abstract	Tanshinone IIA has been reported to exhibit anti-inflammatory effects, while it is not clear whether Tanshinone IIA has protective role in vitiligo. Premelanosome (PMEL) CD8
MeSH term(s)	Abietanes/pharmacology ; Animals ; CD8-Positive T-Lymphocytes ; Mice ; Proto-Oncogene Proteins c-akt ; Vitiligo/drug therapy
Chemical Substances	Abietanes ; tanshinone (03UUH3J385) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
Language	English
Publishing date	2021-08-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	1354801-3
ISSN	1529-8019 ; 1396-0296
ISSN (online)	1529-8019
ISSN	1396-0296
DOI	10.1111/dth.15086
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Zs.A 5181: Show issues

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Article: Study on the Effect of Different Concentrations of SO

Zhang, Baoxiang / Cao, Weiyu / Li, Changyu / Liu, Yingxue / Zhao, Zihao / Qin, Hongyan / Fan, Shutian / Xu, Peilei / Yang, Yiming / Lu, Wenpeng

Foods (Basel, Switzerland)

2024 Volume 13, Issue 8

Abstract: ... ...

Abstract	SO
Language	English
Publishing date	2024-04-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods13081247
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Article ; Online: Redirection Using Double Pulley Technique for Snapping Triceps Tendon: A Case Report and Technique Note.

Zhang, Baoxiang / Zhang, Hao / Zhang, Qiang

Orthopaedic surgery

2020 Volume 12, Issue 5, Page(s) 1520–1525

Abstract: Background: Snapping triceps tendon is an increasingly recognized clinical entity, which is associated with a variety of pathologic factors. The causative factors include inherited structural or developmental variations, post-traumatic malalignment, and ...

Abstract	Background: Snapping triceps tendon is an increasingly recognized clinical entity, which is associated with a variety of pathologic factors. The causative factors include inherited structural or developmental variations, post-traumatic malalignment, and other reasons. The main complaint of patients with snapping lateral triceps are the snapping sensation, mild muscle weakness of elbow extension, with or without tenderness in distal triceps tendon. Many treatment options have been reported previously, including tendon resection and redirection. Case presentation: We present the case of a 19-year-old boy with post-traumatic distal lateral head of triceps tendon dislocation who complained of extension weakness and snapping sensation in his left elbow. Then, we used two-strand-overhand locking (TSOL) knot combined with double pulley technique to redirect the snapping triceps tendon. Conclusion: The patient recovered well after the operation without complaining of discomfort. This fixing and redirection tendon technique, described previously for repairing rotator cuff tears, may be applied in a similar fashion for the snapping triceps tendon with promising clinical results.
MeSH term(s)	Elbow Joint/injuries ; Elbow Joint/surgery ; Humans ; Male ; Muscle, Skeletal/injuries ; Muscle, Skeletal/surgery ; Reconstructive Surgical Procedures/methods ; Suture Techniques ; Tendon Injuries/surgery ; Young Adult
Language	English
Publishing date	2020-11-16
Publishing country	Australia
Document type	Case Reports ; Journal Article
ZDB-ID	2503162-4
ISSN	1757-7861 ; 1757-7853 ; 1757-7861
ISSN (online)	1757-7861 ; 1757-7853
ISSN	1757-7861
DOI	10.1111/os.12772
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Zs.A 6786: Show issues

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Article ; Online: Clinical outcomes of a combined arthroscopic and mini-open Outerbridge-Kashiwagi procedure for elbow osteoarthritis.

Liao, Weixiong / Zhang, Baoxiang / Fu, Yangmu / Zhang, Qiang

Journal of shoulder and elbow surgery

2020 Volume 29, Issue 12, Page(s) 2646–2653

Abstract: Background: To evaluate the short-term clinical outcomes of a modified Outerbridge-Kashiwagi (O-K) procedure in the treatment of elbow osteoarthritis.: Methods: Between January 2012 and December 2016, 27 patients with elbow osteoarthritis were ... ...

Abstract	Background: To evaluate the short-term clinical outcomes of a modified Outerbridge-Kashiwagi (O-K) procedure in the treatment of elbow osteoarthritis. Methods: Between January 2012 and December 2016, 27 patients with elbow osteoarthritis were treated with a modified O-K procedure combining mini-open and arthroscopic technique in our institution. All patients with primary osteoarthritis and post-traumatic degenerative osteoarthritis of the elbow were included in the study if they had undergone the modified O-K procedure. Clinical outcomes were assessed using the visual analog scale (VAS), degree of flexion, extension loss, arc of motion, Mayo Elbow Performance Score (MEPS), and radiographs. Results: Twenty-five patients with a mean age of 47.2 years (range, 21-69 years) at surgery were followed up for a mean of 54.5 months (range, 27-86 months). The VAS improved from 8.0 ± 1.4 (range, 6-10) preoperatively to 1.3 ± 1.1 (range, 0-3) at the final follow-up (P < .001), degree of flexion from 115.2° ± 12.0° (range, 90°-135°) to 130.6° ± 6.3° (range, 120°-140°) (P < .001), extension loss from 31.2° ± 15.0° (range, 10°-60°) to 10.2° ± 7.7° (range, 0°-30°) (P < .001), arc of motion from 84.0° ± 18.8° (range, 55°-120°) to 120.4° ± 9.3° (range, 105°-135°) (P < .001), and MEPS from 55.8 ± 8.1 (range, 40-70) to 88.4 ± 7.2 (range, 70-100) (P < .001). Radiographs at the final follow-up showed that 9 patients (36%) had significant recurrence of bone formation within the fenestration of the olecranon fossa. One patient developed delayed-onset ulnar neuropathy, with only slight numbness in the ulnar nerve distribution 6 months after surgery. Conclusions: The modified O-K procedure is safe and effective in pain relief and function restoration in patients with elbow osteoarthritis.
MeSH term(s)	Adult ; Aged ; Arthroscopy/methods ; Arthroscopy/rehabilitation ; Elbow Joint/diagnostic imaging ; Elbow Joint/surgery ; Female ; Humans ; Male ; Middle Aged ; Osteoarthritis/diagnostic imaging ; Osteoarthritis/rehabilitation ; Osteoarthritis/surgery ; Range of Motion, Articular ; Retrospective Studies ; Treatment Outcome ; Young Adult
Language	English
Publishing date	2020-06-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	1170782-3
ISSN	1532-6500 ; 1058-2746
ISSN (online)	1532-6500
ISSN	1058-2746
DOI	10.1016/j.jse.2020.05.007
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Zs.A 3973: Show issues

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Article: [Study on the evaluation of glenoid bone defects by MRI three-dimensional reconstruction].

Zhang, Fei / Xu, Lin / Zhang, Baoxiang / Song, Shoulong / Sheng, Xianhao / Xiong, Wentao / Wang, Ziran / Liao, Weixiong / Zhang, Qiang

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery

2023 Volume 37, Issue 5, Page(s) 551–555

Abstract: Objective: To investigate the feasibility of MRI three-dimensional (3D) reconstruction model in quantifying glenoid bone defect by comparing with CT 3D reconstruction model measurement.: Methods: Forty patients with shoulder anterior dislocation who ... ...

Abstract	Objective: To investigate the feasibility of MRI three-dimensional (3D) reconstruction model in quantifying glenoid bone defect by comparing with CT 3D reconstruction model measurement. Methods: Forty patients with shoulder anterior dislocation who met the selection criteria between December 2021 and December 2022 were admitted as study participants. There were 34 males and 6 females with an average age of 24.8 years (range, 19-32 years). The injury caused by sports injury in 29 cases and collision injury in 6 cases, and 5 cases had no obvious inducement. The time from injury to admission ranged from 4 to 72 months (mean, 28.5 months). CT and MRI were performed on the patients' shoulder joints, and a semi-automatic segmentation of the images was done with 3D slicer software to construct a glenoid model. The length of the glenoid bone defect was measured on the models by 2 physicians. The intra-group correlation coefficient ( Results: The length of the glenoid bone defects measured on MRI 3D reconstruction model was (3.83±1.36) mm/4.00 (0.58, 6.13) mm for physician 1 and (3.91±1.20) mm/3.86 (1.39, 5.96) mm for physician 2. The length of the glenoid bone defects measured on CT 3D reconstruction model was (3.81±1.38) mm/3.80 (0.60, 6.02) mm for physician 1 and (3.99±1.19) mm/4.00 (1.68, 6.38) mm for physician 2. Conclusion: The measurement of glenoid bone defect based on MRI 3D reconstruction model is consistent with that based on CT 3D reconstruction model. MRI can be used instead of CT to measure glenoid bone defects in clinic, and the soft tissue of shoulder joint can be observed comprehensively while reducing radiation.
MeSH term(s)	Male ; Female ; Humans ; Young Adult ; Adult ; Imaging, Three-Dimensional/methods ; Tomography, X-Ray Computed/methods ; Joint Instability ; Shoulder Joint/diagnostic imaging ; Shoulder Dislocation ; Magnetic Resonance Imaging/methods
Language	Chinese
Publishing date	2023-05-15
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	1420212-8
ISSN	1002-1892
ISSN	1002-1892
DOI	10.7507/1002-1892.202301050
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Zs.A 4866: Show issues

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Article: Diversity of Endophytes of

Liu, Yingxue / Lu, Wenpeng / Li, Yang / Zhai, Boyu / Zhang, Baoxiang / Qin, Hongyan / Xu, Peilei / Yang, Yiming / Fan, Shutian / Wang, Yue / Li, Changyu / Zhao, Jianjun / Ai, Jun

Life (Basel, Switzerland)

2024 Volume 14, Issue 1

Abstract: The seasonal changes in environmental conditions can alter the growth states of host plants, thereby affecting the living environment of endophytes and forming different endophytic communities. This study employs Illumina MiSeq next-generation sequencing ...

Abstract	The seasonal changes in environmental conditions can alter the growth states of host plants, thereby affecting the living environment of endophytes and forming different endophytic communities. This study employs Illumina MiSeq next-generation sequencing to analyze the 16SrRNA and ITS rDNA of endophytes in 24 samples of
Language	English
Publishing date	2024-01-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662250-6
ISSN	2075-1729
ISSN	2075-1729
DOI	10.3390/life14010149
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Article ; Online: Stabilizing Mechanisms in Patients Treated Using Hill-Sachs Remplissage With Bankart Repair in Abduction-External Rotation Position.

Zhang, Fei / Liao, Weixiong / Chen, Xianghui / Zhang, Baoxiang / Xu, Lin / Wang, Xiaolin / Zhu, Yaqiong / Fu, Yangmu / Xiong, Wentao / Song, Shoulong / Sheng, Xianhao / Gao, Huayi / Lai, Shengwei / Zhang, Qiang

The American journal of sports medicine

2024 Volume 52, Issue 3, Page(s) 603–612

Abstract: Background: Hill-Sachs lesion (HSL) remplissage with Bankart repair (RMBR) provides a minimally invasive solution for treating HSLs and glenoid bone defects of <25%. The infraspinatus tendon is inserted into the HSL during the remplissage process, ... ...

Abstract	Background: Hill-Sachs lesion (HSL) remplissage with Bankart repair (RMBR) provides a minimally invasive solution for treating HSLs and glenoid bone defects of <25%. The infraspinatus tendon is inserted into the HSL during the remplissage process, causing the infraspinatus to shift medially, leading to an unknown effect on glenohumeral alignment during the resting abduction-external rotation (ABER) and muscle-active states. Purpose/hypothesis: The purpose of this study was to evaluate the possible check-rein effect and muscle-active control in stabilizing the glenohumeral joint after RMBR in vivo. We hypothesized that the check-rein effect and active control would stabilize the glenohumeral joint in the ABER position in patients after RMBR. Study design: Controlled laboratory study. Methods: We included 42 participants-22 patients in group A who met the inclusion criteria after RMBR and 20 healthy participants in group B without shoulder laxity. Three-dimensional magnetic resonance imaging was performed to analyze the alignment relationship of the glenohumeral joint with and without muscular activity. Ultrasonic shear wave elastography was used to evaluate the elastic properties of the anterior capsule covered with the anterior bands of the inferior glenohumeral ligament. Results: Patients who underwent RMBR demonstrated more posterior (-1.81 ± 1.19 mm vs -0.76 ± 1.25 mm; Conclusion: The check-rein effect and muscle-active control act as stabilizing mechanisms in RMBR during the ABER position. Clinical relevance: Stabilizing mechanisms in RMBR during the ABER position include the check-rein effect and muscle-active control.
MeSH term(s)	Humans ; Shoulder Joint/diagnostic imaging ; Shoulder Joint/surgery ; Rotator Cuff ; Scapula ; Bankart Lesions ; Elasticity
Language	English
Publishing date	2024-01-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	197482-8
ISSN	1552-3365 ; 0363-5465
ISSN (online)	1552-3365
ISSN	0363-5465
DOI	10.1177/03635465231220373
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Zs.B 1910: Show issues

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Article ; Online: Polymeric nanoparticles containing rapamycin and autoantigen induce antigen-specific immunological tolerance for preventing vitiligo in mice.

Zhang, Xia / Liu, Daji / He, Minghong / Lin, Mao / Tu, Caixia / Zhang, Baoxiang

Human vaccines & immunotherapeutics

2021 Volume 17, Issue 7, Page(s) 1923–1929

Abstract: Vitiligo is an autoimmune disease in which pigment is lost in patches of the skin. ... ...

Abstract	Vitiligo is an autoimmune disease in which pigment is lost in patches of the skin. CD4
MeSH term(s)	Animals ; Autoantigens ; Dendritic Cells ; Mice ; Nanoparticles ; Sirolimus/pharmacology ; Vitiligo
Chemical Substances	Autoantigens ; Sirolimus (W36ZG6FT64)
Language	English
Publishing date	2021-02-22
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2664176-8
ISSN	2164-554X ; 2164-5515
ISSN (online)	2164-554X
ISSN	2164-5515
DOI	10.1080/21645515.2021.1872342
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Zs.A 6967: Show issues

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Article ; Online: Apigenin protects human melanocytes against oxidative damage by activation of the Nrf2 pathway.

Zhang, Baoxiang / Wang, Jing / Zhao, Guodong / Lin, Mao / Lang, Yong / Zhang, Diancai / Feng, Dianqin / Tu, Caixia

Cell stress & chaperones

2020 Volume 25, Issue 2, Page(s) 277–285

Abstract: Vitiligo is a chronic, autoimmune destruction of melanocytes, resulting in progressively expanding depigmented skin patches. Severity of the disorder, which affects approximately 1% of humans, may be mitigated using topical corticosteroids combined with ... ...

Abstract	Vitiligo is a chronic, autoimmune destruction of melanocytes, resulting in progressively expanding depigmented skin patches. Severity of the disorder, which affects approximately 1% of humans, may be mitigated using topical corticosteroids combined with phototherapy; along with other clinical strategies; however, no definitive cures are currently available. Here, the capacity of apigenin, a plant-derived aglycone, to inhibit oxidative stress-mediated melanocyte depletion in vitro using a PIG3V vitiligo perilesional melanocyte cell model is evaluated. PIG3V cells, treated with selected doses of apigenin, were challenged with H
MeSH term(s)	Apigenin/pharmacology ; Catalase/metabolism ; Cell Line ; Cell Survival/drug effects ; Glutathione Peroxidase/metabolism ; Humans ; Melanocytes/drug effects ; Melanocytes/pathology ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress/drug effects ; Protective Agents/pharmacology ; Superoxide Dismutase/metabolism ; Vitiligo/drug therapy
Chemical Substances	NF-E2-Related Factor 2 ; NFE2L2 protein, human ; Protective Agents ; Apigenin (7V515PI7F6) ; Catalase (EC 1.11.1.6) ; Glutathione Peroxidase (EC 1.11.1.9) ; Superoxide Dismutase (EC 1.15.1.1)
Language	English
Publishing date	2020-01-18
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1362749-1
ISSN	1466-1268 ; 1355-8145
ISSN (online)	1466-1268
ISSN	1355-8145
DOI	10.1007/s12192-020-01071-7
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Zs.A 4797: Show issues

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