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  1. Book ; Online ; E-Book: Atlas of lung pathology

    Zhang, Chen / Myers, Jeffrey L.

    (Atlas of anatomic pathology)

    2018  

    Author's details Chen Zhang, Jeffrey L. Myers editors
    Series title Atlas of anatomic pathology
    Keywords Pathology
    Subject code 616.07
    Language English
    Size 1 Online-Ressource (LXXI, 284 Seiten), Illustrationen
    Publisher Springer
    Publishing place New York, NY
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019848002
    ISBN 978-1-4939-8689-7 ; 9781493986873 ; 1-4939-8689-9 ; 1493986872
    DOI 10.1007/978-1-4939-8689-7
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Synaptic Assembly and Neural Circuit Development

    Ko, Jaewon / Zhang, Chen

    2018  

    Keywords Neurosciences. Biological psychiatry. Neuropsychiatry ; Science (General)
    Size 1 electronic resource (191 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020101932
    ISBN 9782889456307 ; 2889456307
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Research on Literature Clustering Algorithm for Massive Scientific and Technical Literature Query Service.

    Zhang, Chen

    Computational intelligence and neuroscience

    2022  Volume 2022, Page(s) 3392489

    Abstract: Traditional science and technology literature search mainly provides users with reliable and detailed information materials and services through technical means, data resources, and service strategies. With the development of network technology, computer ...

    Abstract Traditional science and technology literature search mainly provides users with reliable and detailed information materials and services through technical means, data resources, and service strategies. With the development of network technology, computer technology, and information technology, digital information resources are increasing day by day, which continuously impact the traditional knowledge service mode. Some traditional technical methods and service means can no longer meet the information needs of users under large data sets. This paper proposes a model of large-scale literature search service in the context of big data by studying the technical means and service modes used for scientific and technical literature search in universities in the era of big data. Specifically, this paper proposes a method for fast literature retrieval by combining R-tree indexing for the characteristics of diverse data types and large data volume of science and technology literature. The method uses an improved k-mean clustering algorithm to construct an R-tree clustering model and improve the retrieval efficiency of the system by retrieving scientific and technical literature data through R-tree indexing. Experiments on university science and technology literature datasets show that the method in this paper improves both efficiency and precision when searching literature.
    MeSH term(s) Algorithms ; Big Data ; Cluster Analysis ; Humans ; Publications ; Technology
    Language English
    Publishing date 2022-08-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2388208-6
    ISSN 1687-5273 ; 1687-5273
    ISSN (online) 1687-5273
    ISSN 1687-5273
    DOI 10.1155/2022/3392489
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: Work State-Centric AI Agents

    Zhang, Chen

    Design, Implementation, and Management of Cognitive Work Threads

    2023  

    Abstract: AI agents excel in executing predefined tasks, but the dynamic management of work state information during task execution remains an underexplored area. We propose a work state-centric AI agent model employing "work notes" to record and reflect the state ...

    Abstract AI agents excel in executing predefined tasks, but the dynamic management of work state information during task execution remains an underexplored area. We propose a work state-centric AI agent model employing "work notes" to record and reflect the state throughout task execution. This paper details the model's architecture, featuring worker threads for task oversight, planner modules for task decomposition and planning, and executor modules for performing subtasks using a ReAct-inspired thought-action loop. We provide an exhaustive work state record incorporating plans and outcomes, constituting a comprehensive work journal. Our results show that this model not only improves task execution efficiency but also lays a solid foundation for subsequent task analysis and auditing.
    Keywords Computer Science - Computation and Language ; Computer Science - Artificial Intelligence
    Publishing date 2023-11-16
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Thesis ; Online: Decoding the organohalide-respiration potential of Aarhus bay sediments

    Zhang, Chen

    2023  

    Keywords Life Science
    Language English
    Publisher Wageningen University
    Publishing country nl
    Document type Thesis ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: TFP/LCHAD Deficiency Due to HADHA Gene Mutation.

    Chen, Qiao-Lin / Zhang, Chen-Mei

    Clinical pediatrics

    2024  , Page(s) 99228241233099

    Language English
    Publishing date 2024-02-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/00099228241233099
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 454: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Widespread Peptide Surfactants with Post-translational

    Zhang, Chen / Seyedsayamdost, Mohammad R

    bioRxiv : the preprint server for biology

    2024  

    Abstract: Bacteria produce a variety of peptides to mediate nutrient acquisition, microbial interactions, and other physiological processes. Of special interest are surface-active peptides that aid in growth and development. Herein, we report the structure and ... ...

    Abstract Bacteria produce a variety of peptides to mediate nutrient acquisition, microbial interactions, and other physiological processes. Of special interest are surface-active peptides that aid in growth and development. Herein, we report the structure and characterization of clavusporins, unusual and hydrophobic ribosomal peptides with multiple
    Language English
    Publishing date 2024-01-24
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.01.23.576971
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Anti

    Yang, Heng / Zhang, Chen

    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences

    2024  Volume 47, Issue 8, Page(s) 1099–1107

    Abstract: Objectives: Epilepsy is a syndrome of central nervous system dysfunction caused by many reasons, which is mainly characterized by abnormal discharge of neurons in the brain. Therefore, finding new targets for epilepsy therapy has always been the focus ... ...

    Title translation 2-脱氧-
    Abstract Objectives: Epilepsy is a syndrome of central nervous system dysfunction caused by many reasons, which is mainly characterized by abnormal discharge of neurons in the brain. Therefore, finding new targets for epilepsy therapy has always been the focus and hotspot in neurological research field. Studies have found that 2-deoxy-
    Methods: A magnesium-free epilepsy model was established and randomly divided into a control group, an epilepsy group (EP group), an EP+2-DG group, and miR-194 groups (including EP+miR-194 mimic, EP+miR-194 mimic+2-DG, EP+miR-194 mimic control, EP+miR-194 inhibitor, EP+miR-194 inhibitor+2-DG, and EP+miR-194 inhibitor control groups). The 2-DG was used to intervene miR-194 mimics, patch-clamp method was used to detect the spontaneous recurrent epileptiform discharges, real-time PCR was used to detect neuronal
    Results: Compared with the control group, there was no significant difference in the amplitude of spontaneous discharge potential in the EP group (
    Conclusions: The 2-DG might play an anti-epilepsy effect by up-regulating K
    MeSH term(s) Adenosine Triphosphate ; Anticonvulsants ; Deoxyglucose/pharmacology ; Epilepsy/genetics ; Glucose ; Humans ; MicroRNAs/genetics ; Potassium Channels, Inwardly Rectifying/genetics ; Potassium Channels, Inwardly Rectifying/metabolism ; RNA, Messenger/metabolism ; Signal Transduction
    Chemical Substances Anticonvulsants ; MIRN194 microRNA, human ; MicroRNAs ; Potassium Channels, Inwardly Rectifying ; RNA, Messenger ; Adenosine Triphosphate (8L70Q75FXE) ; Deoxyglucose (9G2MP84A8W) ; Glucose (IY9XDZ35W2)
    Language Chinese
    Publishing date 2024-03-20
    Publishing country China
    Document type Journal Article
    ZDB-ID 2168533-2
    ISSN 1672-7347
    ISSN 1672-7347
    DOI 10.11817/j.issn.1672-7347.2022.220111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2681: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Proteomics study of bone tissue around ameloblastoma and the potential mechanism of CD36 in bone remodelling.

    Zhang, Chen-Xi / Man, Qi-Wen

    The British journal of oral & maxillofacial surgery

    2024  

    Abstract: Ameloblastoma (AM) is characterised by local aggressiveness and bone resorption. To our knowledge, the proteomic profile of bone adjacent to AM has not previously been explored. We therefore looked at the differential proteins in cancellous bone (CB) ... ...

    Abstract Ameloblastoma (AM) is characterised by local aggressiveness and bone resorption. To our knowledge, the proteomic profile of bone adjacent to AM has not previously been explored. We therefore looked at the differential proteins in cancellous bone (CB) adjacent to AM and normal CB from the mandible. CB proteins were extracted, purified, quantified, and analysed by liquid chromatography-mass spectrometry (LC-MS) using samples from five patients with AM. These proteins were further investigated using gene ontology for additional functional annotation and enrichment. Proteins that met the screening requirements of expression difference ploidy > 1.5-fold (upregulation and downregulation) and p < 0.05 were subsequently deemed differential proteins. Immunohistochemical staining was performed to confirm the above findings. Compared with normal mandibular CB, 151 differential proteins were identified in CB adjacent to the mandibular AM. These were mainly linked to cellular catabolic processes, lipid metabolism, and fatty acids (FA) metabolism. LC-MS and immunohistochemistry showed that CD36 was one of the notably decreased proteins in CB bordering the AM compared with normal mandibular CB (p = 0.0066 and p = 0.0095, respectively). CD36 expression in CB correlates with bone remodelling in AM, making CD36 a viable target for therapeutic approaches.
    Language English
    Publishing date 2024-01-04
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 605685-4
    ISSN 1532-1940 ; 0266-4356
    ISSN (online) 1532-1940
    ISSN 0266-4356
    DOI 10.1016/j.bjoms.2024.01.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.238: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: The Golden Proportion in Nasal Aesthetics for East Asians.

    Zhang, Chen

    Aesthetic surgery journal

    2021  Volume 42, Issue 5, Page(s) NP368–NP370

    MeSH term(s) Asians ; Esthetics ; Humans ; Nose/surgery
    Language English
    Publishing date 2021-12-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2087022-X
    ISSN 1527-330X ; 1090-820X ; 1084-0761
    ISSN (online) 1527-330X
    ISSN 1090-820X ; 1084-0761
    DOI 10.1093/asj/sjab406
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5721: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 570: Show issues

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