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  1. Article ; Online: Understanding and eliminating the reductant interference on Chromium VI measurement with USEPA method 3060A.

    Yu, Huilin / Zhu, Hongtao / Zhang, Danfeng / Wang, Xingrun

    The Science of the total environment

    2023  Volume 879, Page(s) 163192

    Abstract: Excessive reductants are used in engineering to ensure a reliable remediation effect of chromite ore processing residue (COPR), however, re-yellowing phenomenon of remediated COPR occurs after some time though the Cr(VI) content meets regulatory ... ...

    Abstract Excessive reductants are used in engineering to ensure a reliable remediation effect of chromite ore processing residue (COPR), however, re-yellowing phenomenon of remediated COPR occurs after some time though the Cr(VI) content meets regulatory requirements after curing period. This problem is due to a negative bias on Cr(VI) determination using USEPA method 3060A. To address this issue, this study tried to reveal the interference mechanisms and proposed two methods to amend the bias. Results of ion concentrations, UV-Vis spectrum, XRD, and XPS together showed that Cr(VI) was reduced by ions (Fe
    Language English
    Publishing date 2023-03-31
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.163192
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  2. Article: Pathological changes in the brain after peripheral burns.

    Chen, Jigang / Zhang, Danfeng / Zhang, Junhui / Wang, Yanni

    Burns & trauma

    2023  Volume 11, Page(s) tkac061

    Abstract: Brain injuries are common complications in patients with thermal burns and are associated with unpleasant outcomes. In clinical settings, it was once believed that brain injuries were not major pathological processes after burn, at least in part due to ... ...

    Abstract Brain injuries are common complications in patients with thermal burns and are associated with unpleasant outcomes. In clinical settings, it was once believed that brain injuries were not major pathological processes after burn, at least in part due to the unavailability of specific clinical manifestations. Burn-related brain injuries have been studied for more than a century, but the underlying pathophysiology has not been completely clarified. This article reviews the pathological changes in the brain following peripheral burns at the anatomical, histological, cytological, molecular and cognitive levels. Therapeutic indications based on brain injury as well as future directions for research have been summarized and proposed.
    Language English
    Publishing date 2023-02-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2775996-9
    ISSN 2321-3876 ; 2321-3868
    ISSN (online) 2321-3876
    ISSN 2321-3868
    DOI 10.1093/burnst/tkac061
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  3. Article ; Online: Understanding and eliminating the reductant interference on Chromium VI measurement with USEPA method 3060A

    Yu, Huilin / Zhu, Hongtao / Zhang, Danfeng / Wang, Xingrun

    Science of the Total Environment. 2023 June, v. 879 p.163192-

    2023  

    Abstract: Excessive reductants are used in engineering to ensure a reliable remediation effect of chromite ore processing residue (COPR), however, re-yellowing phenomenon of remediated COPR occurs after some time though the Cr(VI) content meets regulatory ... ...

    Abstract Excessive reductants are used in engineering to ensure a reliable remediation effect of chromite ore processing residue (COPR), however, re-yellowing phenomenon of remediated COPR occurs after some time though the Cr(VI) content meets regulatory requirements after curing period. This problem is due to a negative bias on Cr(VI) determination using USEPA method 3060A. To address this issue, this study tried to reveal the interference mechanisms and proposed two methods to amend the bias. Results of ion concentrations, UV–Vis spectrum, XRD, and XPS together showed that Cr(VI) was reduced by ions (Fe²⁺, S₅²⁻) in the digestion stage of USEPA method 3060A, and as a result, method 7196A would not reflect the true Cr(VI) concentration. The interference on Cr(VI) determination generated by excess reductants mainly occurs during the curing period of remediated COPR, but it decreases over time as reductants being oxidized gradually by the air. Compared with the thermal oxidation, the chemical oxidation with K₂S₂O₈ prior to alkaline digestion performs better to eliminate the masking effect brought by excess reductants. This study provides an approach on how to accurately determine the Cr(VI) concentration in the remediated COPR. It might be helpful to reduce the occurrence possibility of re-yellowing phenomenon.
    Keywords United States Environmental Protection Agency ; air ; chromium ; digestion ; environment ; oxidation ; reducing agents ; remediation ; wet digestion method ; COPR ; USEPA method 3060A ; Interference ; FeSO4 ; CaS5 ; Cr(VI)
    Language English
    Dates of publication 2023-06
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.163192
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  4. Article: AFB

    Yang, Peizhou / Wu, Wenjing / Zhang, Danfeng / Cao, Lili / Cheng, Jieshun

    Metabolites

    2023  Volume 13, Issue 7

    Abstract: Aflatoxin pollution poses great harm to human and animal health and causes huge economic losses. The biological detoxification method that utilizes microorganisms and their secreted enzymes to degrade aflatoxin has the advantages of strong specificity, ... ...

    Abstract Aflatoxin pollution poses great harm to human and animal health and causes huge economic losses. The biological detoxification method that utilizes microorganisms and their secreted enzymes to degrade aflatoxin has the advantages of strong specificity, high efficiency, and no pollution inflicted onto the environment. In this study,
    Language English
    Publishing date 2023-06-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662251-8
    ISSN 2218-1989
    ISSN 2218-1989
    DOI 10.3390/metabo13070785
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  5. Article ; Online: Curcumin inhibits Aspergillus flavus infection and aflatoxin production possibly by inducing ROS burst

    Zhang, Danfeng / Yang, Youyang / Yao, Bangben / Hu, Tingting / Ma, Zhitao / Shi, Wei / Ye, Yingwang

    Food Research International. 2023 May, v. 167 p.112646-

    2023  

    Abstract: Aspergillus flavus contamination is common in various food and feed ingredients, and it poses to serious threats to human and animal health. Curcumin is a plant-derived polyphenol that exhibits antifungal activity. In this study, the antifungal effect of ...

    Abstract Aspergillus flavus contamination is common in various food and feed ingredients, and it poses to serious threats to human and animal health. Curcumin is a plant-derived polyphenol that exhibits antifungal activity. In this study, the antifungal effect of curcumin on A. flavus was evaluated, and the underlying mechanism was investigated. Curcumin effectively decreased aflatoxin B1 synthesis and suppressed A. flavus infection in peanut. Curcumin inhibited the mycelial growth and sporulation of A. flavus. Ergosterol biosynthesis in A. flavus was suppressed, and cell membrane permeability was enhanced. The pathogenicity of A. flavus was also reduced by curcumin treatment. Curcumin induced ROS burst in the hyphae of A. flavus, and those damages could be reversed by exogenous superoxide dismutase, suggesting that curcumin inhibited A. flavus possibly via inducing oxidative stress. These results indicate that curcumin has the potential to be used as a preservative to control A. flavus contamination in food and feedstuff.
    Keywords Aspergillus flavus ; aflatoxin B1 ; animal and human health ; antifungal properties ; biosynthesis ; curcumin ; ergosterol ; feeds ; food research ; hyphae ; membrane permeability ; mycelium ; oxidative stress ; pathogenicity ; peanuts ; polyphenols ; sporulation ; superoxide dismutase ; Aflatoxin ; Peanut
    Language English
    Dates of publication 2023-05
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 1111695-x
    ISSN 1873-7145 ; 0963-9969
    ISSN (online) 1873-7145
    ISSN 0963-9969
    DOI 10.1016/j.foodres.2023.112646
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  6. Book ; Online: An Optimal and Scalable Matrix Mechanism for Noisy Marginals under Convex Loss Functions

    Xiao, Yingtai / He, Guanlin / Zhang, Danfeng / Kifer, Daniel

    2023  

    Abstract: Noisy marginals are a common form of confidentiality-protecting data release and are useful for many downstream tasks such as contingency table analysis, construction of Bayesian networks, and even synthetic data generation. Privacy mechanisms that ... ...

    Abstract Noisy marginals are a common form of confidentiality-protecting data release and are useful for many downstream tasks such as contingency table analysis, construction of Bayesian networks, and even synthetic data generation. Privacy mechanisms that provide unbiased noisy answers to linear queries (such as marginals) are known as matrix mechanisms. We propose ResidualPlanner, a matrix mechanism for marginals with Gaussian noise that is both optimal and scalable. ResidualPlanner can optimize for many loss functions that can be written as a convex function of marginal variances (prior work was restricted to just one predefined objective function). ResidualPlanner can optimize the accuracy of marginals in large scale settings in seconds, even when the previous state of the art (HDMM) runs out of memory. It even runs on datasets with 100 attributes in a couple of minutes. Furthermore ResidualPlanner can efficiently compute variance/covariance values for each marginal (prior methods quickly run out of memory, even for relatively small datasets).
    Keywords Computer Science - Databases ; Computer Science - Cryptography and Security ; Computer Science - Machine Learning
    Subject code 006
    Publishing date 2023-05-14
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Hydrogen Peroxide Promotes Tomato Leaf Senescence by Regulating Antioxidant System and Hydrogen Sulfide Metabolism.

    Yu, Yue / Wang, Siyue / Guo, Wentong / Geng, Meihui / Sun, Ying / Li, Wanjie / Yao, Gaifang / Zhang, Danfeng / Zhang, Hua / Hu, Kangdi

    Plants (Basel, Switzerland)

    2024  Volume 13, Issue 4

    Abstract: Hydrogen peroxide ( ... ...

    Abstract Hydrogen peroxide (H
    Language English
    Publishing date 2024-02-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants13040475
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  8. Article ; Online: Curcumin inhibits Aspergillus flavus infection and aflatoxin production possibly by inducing ROS burst.

    Zhang, Danfeng / Yang, Youyang / Yao, Bangben / Hu, Tingting / Ma, Zhitao / Shi, Wei / Ye, Yingwang

    Food research international (Ottawa, Ont.)

    2023  Volume 167, Page(s) 112646

    Abstract: Aspergillus flavus contamination is common in various food and feed ingredients, and it poses to serious threats to human and animal health. Curcumin is a plant-derived polyphenol that exhibits antifungal activity. In this study, the antifungal effect of ...

    Abstract Aspergillus flavus contamination is common in various food and feed ingredients, and it poses to serious threats to human and animal health. Curcumin is a plant-derived polyphenol that exhibits antifungal activity. In this study, the antifungal effect of curcumin on A. flavus was evaluated, and the underlying mechanism was investigated. Curcumin effectively decreased aflatoxin B1 synthesis and suppressed A. flavus infection in peanut. Curcumin inhibited the mycelial growth and sporulation of A. flavus. Ergosterol biosynthesis in A. flavus was suppressed, and cell membrane permeability was enhanced. The pathogenicity of A. flavus was also reduced by curcumin treatment. Curcumin induced ROS burst in the hyphae of A. flavus, and those damages could be reversed by exogenous superoxide dismutase, suggesting that curcumin inhibited A. flavus possibly via inducing oxidative stress. These results indicate that curcumin has the potential to be used as a preservative to control A. flavus contamination in food and feedstuff.
    MeSH term(s) Humans ; Aflatoxins/metabolism ; Aspergillus flavus ; Reactive Oxygen Species/metabolism ; Curcumin/pharmacology ; Curcumin/metabolism ; Antifungal Agents/pharmacology ; Antifungal Agents/metabolism
    Chemical Substances Aflatoxins ; Reactive Oxygen Species ; Curcumin (IT942ZTH98) ; Antifungal Agents
    Language English
    Publishing date 2023-02-26
    Publishing country Canada
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1111695-x
    ISSN 1873-7145 ; 0963-9969
    ISSN (online) 1873-7145
    ISSN 0963-9969
    DOI 10.1016/j.foodres.2023.112646
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  9. Article ; Online: Associations of Whole Blood Zinc Levels with Coronary Artery Calcification and Future Cardiovascular Events in CKD Patients.

    Zhang, Danfeng / Zhu, Yuyu / Li, Huan / Wang, Yunfei / Niu, Zheng / Zhou, Wenli / Wang, Deguang

    Biological trace element research

    2023  Volume 202, Issue 1, Page(s) 46–55

    Abstract: This study was conducted to compare the differences of the whole blood zinc concentration in patients with chronic kidney disease (CKD) as compared to healthy controls, and to explore the correlations of the whole blood zinc level with coronary artery ... ...

    Abstract This study was conducted to compare the differences of the whole blood zinc concentration in patients with chronic kidney disease (CKD) as compared to healthy controls, and to explore the correlations of the whole blood zinc level with coronary artery calcification (CAC) and cardiovascular event (CVE) in CKD patients. A total of 170 CKD patients and 62 healthy controls were recruited. The whole blood zinc concentration was determined in using atomic absorption spectroscopy (AAS) method. The degrees of CAC were evaluated by Agatston score based on computed tomography (CT). Regular follow-up visits were performed to record the incidence of CVE, and risk factors were analyzed by COX proportional hazard model and Kaplan-Meier survival curve. There were statistically significant lower zinc levels in CKD patients than in healthy population. The prevalence of CAC was 58.82% in CKD patients. Correlation analysis showed that dialysis duration, intact parathyroid hormone (iPTH), alkaline phosphatase (ALP), 25-hydroxyvitamin D
    MeSH term(s) Humans ; Vascular Calcification ; Coronary Artery Disease ; Renal Insufficiency, Chronic ; Risk Factors ; Zinc
    Chemical Substances Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2023-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 445336-0
    ISSN 1559-0720 ; 0163-4984
    ISSN (online) 1559-0720
    ISSN 0163-4984
    DOI 10.1007/s12011-023-03655-7
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    Zs.B 2323: Show issues Location:
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  10. Article ; Online: DTL is a Novel Downstream Gene of E2F1 that Promotes the Progression of Hepatocellular Carcinoma.

    Dong, Ruiqiang / Zhang, Danhua / Han, Baowei / Xu, Lingxue / Zhang, Danfeng / Cheng, Zhenguo / Qiu, Xinguang

    Current cancer drug targets

    2023  Volume 23, Issue 10, Page(s) 817–828

    Abstract: Background: Hepatocellular carcinoma (HCC), one of the world's most prevalent malignancies, accounts for 90% of primary liver cancer cases. Recent studies have shown an increased expression of denticles E3 ubiquitin protein ligase homolog (DTL) in ... ...

    Abstract Background: Hepatocellular carcinoma (HCC), one of the world's most prevalent malignancies, accounts for 90% of primary liver cancer cases. Recent studies have shown an increased expression of denticles E3 ubiquitin protein ligase homolog (DTL) in several different tumor types, but its function and regulatory mechanisms remain unclear.
    Aims: This study aimed to investigate the expressions of the Cullin4 (CUL4) complex in HCC and elucidate the roles of DTL in HCC cells.
    Methods: The relative expression of the CUL4 complex and its clinical significance were analyzed with The Cancer Genome Atlas (TCGA) data, and the level of DTL was confirmed by immunohistochemistry. The functions of DTL1 and upstream E2F1 were evaluated by a Western blot, MTT, transwell, and xenograft in HCC cell lines.
    Results: The elevated mRNA expression of the CUL4 complex, including CUL4B, DDB1 (Damage Specific DNA Binding Protein 1), and DTL, was associated with the overall survival of HCC patients. We also found that the DTL protein was elevated in HCC tissues, and patients with highly expressed DTL and nucleus-located DTL had a poorer survival time. DTL knockdown significantly inhibited cancer proliferation, migration, and invasion. Further experiments showed that E2F1 was an upstream regulatory molecule of DTL, which was bound to the promoter of DTL, promoting the expression of DTL.
    Conclusion: The study results demonstrate that E2F1-DTL signaling promotes the growth, migration, and invasion of HCC cells, which provides new insights and a potential biological target for future HCC therapies.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/pathology ; Signal Transduction ; Cell Proliferation ; Cell Line, Tumor ; Cell Movement ; Gene Expression Regulation, Neoplastic ; Nuclear Proteins/genetics ; E2F1 Transcription Factor/genetics ; E2F1 Transcription Factor/metabolism ; Cullin Proteins/genetics ; Cullin Proteins/metabolism
    Chemical Substances DTL protein, human ; Nuclear Proteins ; E2F1 protein, human ; E2F1 Transcription Factor ; CUL4B protein, human ; Cullin Proteins
    Language English
    Publishing date 2023-05-02
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2064824-8
    ISSN 1873-5576 ; 1568-0096
    ISSN (online) 1873-5576
    ISSN 1568-0096
    DOI 10.2174/1568009623666230511100246
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