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  1. Book ; Online: Correlation between entropy and generalizability in a neural network

    Zhang, Ge

    2022  

    Abstract: Although neural networks can solve very complex machine-learning problems, the theoretical reason for their generalizability is still not fully understood. Here we use Wang-Landau Mote Carlo algorithm to calculate the entropy (logarithm of the volume of ... ...

    Abstract Although neural networks can solve very complex machine-learning problems, the theoretical reason for their generalizability is still not fully understood. Here we use Wang-Landau Mote Carlo algorithm to calculate the entropy (logarithm of the volume of a part of the parameter space) at a given test accuracy, and a given training loss function value or training accuracy. Our results show that entropical forces help generalizability. Although our study is on a very simple application of neural networks (a spiral dataset and a small, fully-connected neural network), our approach should be useful in explaining the generalizability of more complicated neural networks in future works.
    Keywords Condensed Matter - Statistical Mechanics ; Computer Science - Machine Learning
    Publishing date 2022-07-05
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Primary hospitals in China: current state, challenges, and solutions.

    Wang, Ziyi / Zhang, Ge

    Hepatobiliary surgery and nutrition

    2023  Volume 12, Issue 6, Page(s) 909–911

    Language English
    Publishing date 2023-11-13
    Publishing country China (Republic : 1949- )
    Document type Editorial
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-23-571
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Camrelizumab induced immune related adverse event: Two case reports and literature review.

    Ge, Lingzhi / Chen, Wenfang / Zhang, Ge / Wei, Fangli

    Asian journal of surgery

    2024  

    Language English
    Publishing date 2024-03-23
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2024.03.120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2831: Show issues Location:
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  4. Article ; Online: NOx removal capacity and compressive strength of photocatalytic cementitious materials with various color properties.

    Zhang, Junjie / Tan, Hongbo / Zhang, Ge / Li, Guoxin

    Journal of environmental management

    2024  Volume 356, Page(s) 120605

    Abstract: The photocatalytic cementitious materials (PCM) are expected to alleviate air pollution due to the direct utilization of natural solar energy. However, the color properties of cementitious materials have significant effect on the photocatalytic ... ...

    Abstract The photocatalytic cementitious materials (PCM) are expected to alleviate air pollution due to the direct utilization of natural solar energy. However, the color properties of cementitious materials have significant effect on the photocatalytic performance of PCM. In the present study, the colorful PCM is prepared using various colorants. The effect of color properties of cementitious materials on the NOx removal capacity of PCM is researched, and the related mechanism is analyzed by optical analysis. Furthermore, the effect of colorants on the compressive strength of PCM is studied. Results showed that the NOx removal capacity of PCM is decreased by the presence of colorants. As the 5% of black, yellow, red, and blue colorants are used, the NOx removal capacity of PCM is reduced by 73%, 48%, 21%, and 19%, respectively. Both the nano-TiO
    MeSH term(s) Compressive Strength ; Ultraviolet Rays ; Air Pollution
    Language English
    Publishing date 2024-03-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2024.120605
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Spurious High Platelet Count without PLT Flag(S) in a Patient with Severe Aplastic Anaemia.

    Peng, Luyun / Shi, Rui / Lu, Feng / Zhang, Ge

    Clinical laboratory

    2024  Volume 70, Issue 4

    Abstract: Background: Platelet (PLT) count is one of the most important parameters of automated hematology, as spurious PLT reports could affect medical judgement and bring significant risks. In most cases, spurious PLT will not be reported for review criteria, ... ...

    Abstract Background: Platelet (PLT) count is one of the most important parameters of automated hematology, as spurious PLT reports could affect medical judgement and bring significant risks. In most cases, spurious PLT will not be reported for review criteria, which will be triggered by abnormal PLT histograms and PLT flag(s). Here, we present a case of severe aplastic anemia after hematopoietic stem cell transplantation with spurious high platelet count with normal histogram and no PLT flag(s).
    Methods: The electrical impedance channel (PLT-I) and the fluorescence channel (PLT-F) of Sysmex XN-series hematology analyzer was used to obtain PLT results. Then, the sample was retested by another hematology analyzer MINDRAY BC-7500 [NR] CRP, and incubation was performed to rule out cryoglobulin interference. Furthermore, a microscope was used to estimate the PLT count by the ratio of platelets to red blood cells and observe the morphology of cells.
    Results: Both PLT-I and PLT-F test results were spuriously high, and microscopically assessed platelet counts were relatively reliable. The observed spiny cells and ghost cells caused by hemolysis may have contributed to the inaccuracy of instrumental counting in this case.
    Conclusions: For special hematologic patients, PLT-I with flags may not be sufficient for screening purposes and PLT-F is not always accurate. Multiple testing methods including manual microscopy are needed.
    MeSH term(s) Humans ; Platelet Count/methods ; Anemia, Aplastic/diagnosis ; Reproducibility of Results ; Blood Platelets ; Agmatine/analogs & derivatives ; Oxamic Acid/analogs & derivatives
    Chemical Substances bis(agmatine)oxalamide (151368-32-0) ; Agmatine (70J407ZL5Q) ; Oxamic Acid (QU60N5OPLG)
    Language English
    Publishing date 2024-04-16
    Publishing country Germany
    Document type Case Reports
    ZDB-ID 1307629-2
    ISSN 1433-6510 ; 0941-2131
    ISSN 1433-6510 ; 0941-2131
    DOI 10.7754/Clin.Lab.2023.231119
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Efficacy and potential mechanisms of Ganmai Dazao decoction in treating perimenopausal syndrome: A network pharmacology and meta-analysis.

    Liu, Geng-Xin / Zhang, Ge-di / Yan, Zi-You

    Asian journal of surgery

    2024  

    Language English
    Publishing date 2024-04-18
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2024.04.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2831: Show issues Location:
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  7. Article ; Online: Effect of Huaier granule on prognosis of breast cancer: A single-center propensity score matching retrospective study.

    Guo, Qianqian / Peng, Yuting / Zhang, Ge / Lin, Huan / Chen, Qianjun

    Chinese medical journal

    2024  

    Abstract: Background: Huaier granule is an important medicinal fungus extract widely used in cancer treatment. Previous retrospective studies have reported its effectiveness in breast cancer patients, but the imbalanced baseline characteristics of participants ... ...

    Abstract Background: Huaier granule is an important medicinal fungus extract widely used in cancer treatment. Previous retrospective studies have reported its effectiveness in breast cancer patients, but the imbalanced baseline characteristics of participants could have biased the results. Therefore, this retrospective study aimed to examine the efficacy of Huaier granule on the prognosis of breast cancer patients.
    Methods: In this single-center cohort study, breast cancer patients diagnosed and treated at the Guangdong Provincial Hospital of Chinese Medicine between 2009 and 2017 were selected. The data were retrospectively analyzed and divided into two groups according to whether the patients received Huaier granules. The propensity score matching (PSM) method was used to eliminate selection bias. The disease-free survival (DFS) and overall survival (OS) for these groups were compared using the Kaplan-Meier method and the Cox regression.
    Results: This study included 214 early invasive breast cancer patients, 107 in the Huaier group and 107 in the control group. In the Kaplan-Meier analysis, the 2-year and 5-year DFS rates were significantly different in the Huaier group and control group (hazard ratio [HR], 0.495; 95% confidence interval [CI], 0.257-0.953; P = 0.023). The 2-year and 5-year OS rates were also significantly different (HR, 0.308; 95% CI, 0.148-0.644; P = 0.001). On multivariable Cox regression, Huaier granule was associated with improved DFS (HR, 0.440; 95% CI, 0.223-0.868; P = 0.018) and OS (HR, 0.236; 95% CI, 0.103-0.540; P = 0.001).
    Conclusion: In this retrospective study, Huaier granules improved the DFS and OS of early invasive breast cancer patients, providing real-world evidence for further prospective studies on treating breast cancer with Huaier granules.
    Language English
    Publishing date 2024-01-25
    Publishing country China
    Document type Journal Article
    ZDB-ID 127089-8
    ISSN 2542-5641 ; 0366-6999 ; 1002-0187
    ISSN (online) 2542-5641
    ISSN 0366-6999 ; 1002-0187
    DOI 10.1097/CM9.0000000000002966
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 1207: Show issues Location:
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    Ua VI Zs.425: Show issues Location:
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  8. Article ; Online: Long Non-coding RNA COX10-AS1 Promotes Glioma Progression by Competitively Binding miR-1-3p to Regulate ORC6 Expression.

    Zhang, Ge / Tao, Xiang / Ji, Bao-Wei / Gong, Jie

    Neuroscience

    2024  Volume 540, Page(s) 68–76

    Abstract: Glioma is one of the most common and difficult to cure malignant primary tumors of the central nervous system. Long non-coding RNA (lncRNA) has been reported to play important functions in biological processes of many tumors, including glioma. In our ... ...

    Abstract Glioma is one of the most common and difficult to cure malignant primary tumors of the central nervous system. Long non-coding RNA (lncRNA) has been reported to play important functions in biological processes of many tumors, including glioma. In our study, we aimed to reveal the role and molecular mechanisms of lncRNA COX10-AS1 in regulating the progression of glioma. First of all, we showed that lncRNA COX10-AS1 was significantly increased in glioma tissues and cell lines, and high-expressed COX10-AS1 was associated with a poor prognosis in glioma patients. Moreover, through performing the functional experiments, including CCK-8, colony formation and Transwell assays, we confirmed that COX10-AS1 ablation curbed cell proliferation, migration and invasion in glioblastoma (GBM) cells. In addition, we uncovered that there existed a regulatory relationship that COX10-AS1 upregulated OCR6 by sponging miR-1-3p in GBM cells, and the following rescue assays demonstrated that both miR-1-3p downregulation and origin recognition complex subunit 6 (ORC6) overexpression rescued cell viability, migration and invasion in the COX10-AS1-deficient GBM cells. Consistently, we also verified that COX10-AS1 promoted tumorigenesis of the GBM cells in vivo through modulating the miR-1-3p/ORC6 axis. On the whole, our findings indicated a novel ceRNA pattern in which COX10-AS1 elevated OCR6 expression via sponging miR-1-3p, therefore boosting tumorigenesis in glioma, and we firstly discussed the underlying mechanisms by which the COX10-AS1/miR-1-3p/ORC6 axis affected the progression of glioma.
    MeSH term(s) Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Origin Recognition Complex/genetics ; Origin Recognition Complex/metabolism ; Glioma/genetics ; Glioma/pathology ; Carcinogenesis/genetics ; Cell Line, Tumor ; Glioblastoma/genetics ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Cell Movement/genetics ; Electron Transport Complex IV/metabolism ; Membrane Proteins/genetics ; Alkyl and Aryl Transferases/genetics
    Chemical Substances MicroRNAs ; RNA, Long Noncoding ; Origin Recognition Complex ; ORC6 protein, human ; COX10 protein, human (EC 1.9.3.1) ; Electron Transport Complex IV (EC 1.9.3.1) ; Membrane Proteins ; Alkyl and Aryl Transferases (EC 2.5.-) ; MIRN1 microRNA, human
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 196739-3
    ISSN 1873-7544 ; 0306-4522
    ISSN (online) 1873-7544
    ISSN 0306-4522
    DOI 10.1016/j.neuroscience.2023.09.020
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1215: Show issues Location:
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  9. Article ; Online: Conjugated Polymer-Based Hydrogel Film for a Fast and Sensitive Detection of Fe(Ⅲ) in Vegetables.

    Ding, Xingli / Sheng, Li / Zhang, Ge / Ji, Min / Li, Yu

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 5

    Abstract: Fluorescent film sensors are ideal for the real-time outdoor detection of heavy metal ions of ... ...

    Abstract Fluorescent film sensors are ideal for the real-time outdoor detection of heavy metal ions of Fe
    MeSH term(s) Ferric Compounds ; Polymers/chemistry ; Vegetables ; Cations ; Alginates ; Methylgalactosides
    Chemical Substances Ferric Compounds ; Polymers ; hydrogel film ; Cations ; Alginates ; Methylgalactosides
    Language English
    Publishing date 2024-02-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29050925
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The association between physical activity, self-efficacy, stress self-management and mental health among adolescents.

    Zhang, Ge / Feng, Wanxuan / Zhao, Liangyu / Zhao, Xiuhan / Li, Tuojian

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 5488

    Abstract: This study aimed to explore the interplay between physical activity, self-efficacy, stress self-management and mental health among adolescents. The study gathered data from an online survey conducted among 400 Chinese middle school students (mean age = ... ...

    Abstract This study aimed to explore the interplay between physical activity, self-efficacy, stress self-management and mental health among adolescents. The study gathered data from an online survey conducted among 400 Chinese middle school students (mean age = 13.74 years). The collected data were analyzed using SPSS 27.0 and PROCESS 4.1. The findings indicated a positive and significant relationship between physical activity, self-efficacy, stress self-management, and mental health. Notably, the association between physical activity and mental health was entirely mediated by self-efficacy and stress self-management. Moreover, self-efficacy and stress self-management exhibited a chain mediation effect on the relationship between physical activity and mental health. It is suggested that interventions focusing on physical activity should prioritize strategies for enhancing students' self-efficacy and stress self-management skills as integral components of promoting adolescents' mental health. Future research should delve into identifying specific types of physical activities that have a greater potential to enhance self-efficacy and stress self-management abilities.
    MeSH term(s) Humans ; Adolescent ; Mental Health ; Self Efficacy ; Self-Management ; Exercise ; Asian People
    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-56149-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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