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Book ; Online ; E-Book: Formal methods for the analysis of biomedical ontologies

Zhang, Guo-Qiang / Abeysinghe, Rashmie / Cui, Licong

(Synthesis Lectures on Data, Semantics, and Knowledge)

2022

Author's details	Guo-Qiang Zhang, Rashmie Abeysinghe, Licong Cui
Series title	Synthesis Lectures on Data, Semantics, and Knowledge
Keywords	Engineering/Data processing
Subject code	929.374
Language	English
Size	1 online resource (258 pages)
Publisher	Springer
Publishing place	Cham, Switzerland
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
ISBN	3-031-12131-7 ; 9783031121302 ; 978-3-031-12131-9 ; 3031121309
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Diagnostic value of Procalcitonin, C-reactive protein-to-lymphocyte ratio (CLR), C-reactive protein and neutrophil-to-lymphocyte ratio (NLR) for predicting patients with Bacteraemia in the intensive care unit.

Zhang, Guo-Ming / Gu, Yuan-Yuan

Journal of critical care

2024 Volume 81, Page(s) 154538

Abstract: Background: To explore the diagnostic value of procalcitonin (PCT), C-reactive protein-to-lymphocyte ratio (CLR), C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (NLR) for predicting patients with bacteremia in the intensive care unit (ICU).! ...

Abstract	Background: To explore the diagnostic value of procalcitonin (PCT), C-reactive protein-to-lymphocyte ratio (CLR), C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (NLR) for predicting patients with bacteremia in the intensive care unit (ICU). Methods: This case-control study included 359 patients with suspected bacteremia were divided into a bacteremia group (n = 152) and a control group (n = 207) from September 2018 to April 2023. Patient data were collected using a laboratory information system (LIS). ROC curves for PCT, CLR, CRP, and NLR in predicting patients with bacteremia. Results: For PCT, CLR, CRP and NLR to predict patients with bacteremia in the ICU, the AUCs were 0.991(95%CI: 0.974-0.998), 0.960(95%CI: 0.935-0.978), 0.955(95%CI: 0.928-0.974), and 0.898(95%CI:0.862-0.927), respectively; the optimal thresholds were 0.248 ng/mL, 47.52 mg/10 Conclusions: Compared with those in the control group, PCT, CLR, CRP and NLR were significantly greater in the bacteremia group. The PCT, CLR, CRP, and NLR can all predict the occurrence of bacteremia. The PCT had the highest sensitivity and specificity in predicting bacteremia in ICU patients.
MeSH term(s)	Humans ; Procalcitonin ; C-Reactive Protein/metabolism ; Neutrophils/metabolism ; Case-Control Studies ; Escherichia coli ; Bacteremia/diagnosis ; Lymphocytes/metabolism ; ROC Curve ; Intensive Care Units ; Retrospective Studies ; Biomarkers
Chemical Substances	Procalcitonin ; C-Reactive Protein (9007-41-4) ; Biomarkers
Language	English
Publishing date	2024-02-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	632818-0
ISSN	1557-8615 ; 0883-9441
ISSN (online)	1557-8615
ISSN	0883-9441
DOI	10.1016/j.jcrc.2024.154538
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Article: Perforation of levonorgestrel-releasing intrauterine system found at one month after insertion: A case report.

Zhang, Guo-Rui / Yu, Xin

World journal of clinical cases

2023 Volume 11, Issue 1, Page(s) 172–176

Abstract: Background: The levonorgestrel-releasing intrauterine system (LNG-IUS) is widely used in contraception, menorrhagia, dysmenorrhea and to prevent endometrial hyperplasia during estrogen supplementation. Perforation is more often seen after early ... ...

Abstract	Background: The levonorgestrel-releasing intrauterine system (LNG-IUS) is widely used in contraception, menorrhagia, dysmenorrhea and to prevent endometrial hyperplasia during estrogen supplementation. Perforation is more often seen after early postpartum placement. Perforation of the LNG-IUS occurring one month after placement is rare. Case summary: A 42-year-old female complained of progressive dysmenorrhea and increased menstrual volume. She was diagnosed with adenomyosis and the LNG-IUS was inserted in her uterine cavity. Routine ultrasound examination one month later revealed that the intra-uterine device (IUD) was not found in the uterine cavity, and further X-ray and pelvic magnetic resonance imaging showed an abnormal signal area in the left posterior region of the uterus. Laparoscopic exploratory surgery was performed and the LNG-IUS was found in the left uterosacral ligament. Conclusion: Perforation of a LNG-IUS occurring one month after placement is rare, and is more common in inexperienced operators and after early postpartum placement. When the operation is difficult, ultrasound monitoring is recommended to reduce the risk of IUD perforation. For patients with inadequate surgery, postoperative imaging is recommended to detect potential risks as soon as possible.
Language	English
Publishing date	2023-01-03
Publishing country	United States
Document type	Case Reports
ISSN	2307-8960
ISSN	2307-8960
DOI	10.12998/wjcc.v11.i1.172
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Article ; Online: A Single Measurement System May Not Be Enough for Questionable High Free T4 Levels.

Zhang, Guo-Ming / Zhang, Qian-Jin

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

2023 Volume 33, Issue 10, Page(s) 1210

Abstract: Null. ...

Abstract	Null.
MeSH term(s)	Humans ; Thyroxine ; Triiodothyronine ; Reference Values ; Thyrotropin
Chemical Substances	Thyroxine (Q51BO43MG4) ; Triiodothyronine (06LU7C9H1V) ; Thyrotropin (9002-71-5)
Language	English
Publishing date	2023-10-07
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	2276646-7
ISSN	1681-7168 ; 1022-386X
ISSN (online)	1681-7168
ISSN	1022-386X
DOI	10.29271/jcpsp.2023.10.1210
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Article ; Online: BRWMC: Predicting lncRNA-disease associations based on bi-random walk and matrix completion on disease and lncRNA networks.

Zhang, Guo-Zheng / Gao, Ying-Lian

Computational biology and chemistry

2023 Volume 103, Page(s) 107833

Abstract: Many experiments have proved that long non-coding RNAs (lncRNAs) in humans have been implicated in disease development. The prediction of lncRNA-disease association is essential in promoting disease treatment and drug development. It is time-consuming ... ...

Abstract	Many experiments have proved that long non-coding RNAs (lncRNAs) in humans have been implicated in disease development. The prediction of lncRNA-disease association is essential in promoting disease treatment and drug development. It is time-consuming and laborious to explore the relationship between lncRNA and diseases in the laboratory. The computation-based approach has clear advantages and has become a promising research direction. This paper proposes a new lncRNA disease association prediction algorithm BRWMC. Firstly, BRWMC constructed several lncRNA (disease) similarity networks based on different measurement angles and fused them into an integrated similarity network by similarity network fusion (SNF). In addition, the random walk method is used to preprocess the known lncRNA-disease association matrix and calculate the estimated scores of potential lncRNA-disease associations. Finally, the matrix completion method accurately predicts the potential lncRNA-disease associations. Under the framework of leave-one-out cross-validation and 5-fold cross-validation, the AUC values obtained by BRWMC are 0.9610 and 0.9739, respectively. In addition, case studies of three common diseases show that BRWMC is a reliable method for prediction.
MeSH term(s)	Humans ; RNA, Long Noncoding/genetics ; Computational Biology/methods ; Algorithms
Chemical Substances	RNA, Long Noncoding
Language	English
Publishing date	2023-02-17
Publishing country	England
Document type	Journal Article
ISSN	1476-928X
ISSN (online)	1476-928X
DOI	10.1016/j.compbiolchem.2023.107833
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Article ; Online: CNN sensor based motion capture system application in basketball training and injury prevention.

Chen, ZhiHao / Zhang, GuoQing

Preventive medicine

2023 Volume 174, Page(s) 107644

Abstract: Basketball is a high-intensity sport, and sports injuries often occur. Therefore, how to monitor the sports status of basketball players in real time, discover and prevent the occurrence of sports injuries in time, has become an urgent problem for ... ...

Abstract	Basketball is a high-intensity sport, and sports injuries often occur. Therefore, how to monitor the sports status of basketball players in real time, discover and prevent the occurrence of sports injuries in time, has become an urgent problem for athletes and coaches. In this paper, a motion capture system based on CNN sensor is proposed. Through the application of sensor, real-time monitoring of athletes' motion state, the system can collect athletes' movement track, speed, acceleration, stride frequency, heart rate, energy consumption and other parameters in real time. By analyzing the movement data, it can timely warn and deal with the occurrence of sports injuries. In this paper, convolutional neural network (CNN) is used to process and analyze motion data, so that the motion capture system has higher precision and accuracy. Through the training and optimization of CNN, the system can identify and analyze motion data more accurately, and improve the performance and effect of the motion capture system. The motion capture system based on CNN sensor can realize real-time monitoring and prevention of sports injuries for basketball players, provide more comprehensive, scientific and real-time sports data for athletes and coaches, help them better conduct training and adjust tactics, and improve the competitive level and safety of basketball games.
MeSH term(s)	Humans ; Basketball/injuries ; Basketball/physiology ; Athletic Injuries/prevention & control ; Athletic Injuries/epidemiology ; Motion Capture ; Movement ; Athletes
Language	English
Publishing date	2023-07-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	184600-0
ISSN	1096-0260 ; 0091-7435
ISSN (online)	1096-0260
ISSN	0091-7435
DOI	10.1016/j.ypmed.2023.107644
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Article ; Online: Facile one-pot synthesis of flower-like ellagic acid microparticles incorporating anti-microbial peptides for enhanced wound healing.

Zhang, Guo / Wang, Yu / Qiu, Hua / Lu, Lei

Journal of materials chemistry. B

2024 Volume 12, Issue 2, Page(s) 500–507

Abstract: Anti-microbial peptides (AMPs) have gained significant attention as potential antimicrobial agents due to their cytocompatibility and reduced drug resistance. However, AMPs often suffer from low stability due to their vulnerable molecular structure. This ...

Abstract	Anti-microbial peptides (AMPs) have gained significant attention as potential antimicrobial agents due to their cytocompatibility and reduced drug resistance. However, AMPs often suffer from low stability due to their vulnerable molecular structure. This study presents a one-pot synthesis method for ellagic acid (EA)-based, flower-like AMPs@EAMP particles, combining the antibacterial properties of EA with AMPs. The resulting particles exhibit an enlarged surface area for the adsorption or embedding of AMPs, enhancing their antibacterial efficacy. Furthermore,
MeSH term(s)	Ellagic Acid/pharmacology ; Antimicrobial Cationic Peptides/chemistry ; Escherichia coli ; Wound Healing ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry
Chemical Substances	Ellagic Acid (19YRN3ZS9P) ; Antimicrobial Cationic Peptides ; Anti-Bacterial Agents
Language	English
Publishing date	2024-01-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2702241-9
ISSN	2050-7518 ; 2050-750X
ISSN (online)	2050-7518
ISSN	2050-750X
DOI	10.1039/d3tb02016a
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Article ; Online: The impact of smart city construction (SCC) on pollution emissions (PE): evidence from China.

Zhang, GuoWei / Sun, XianMin / Zhong, Shen

Scientific reports

2024 Volume 14, Issue 1, Page(s) 6633

Abstract: Based on panel data from 210 prefecture-level cities in China from 2003 to 2021, this study employs the Time-Varying Differences-in-Differences (Time-Varying DID) approach to systematically examine the impact of smart city construction on pollution ... ...

Abstract	Based on panel data from 210 prefecture-level cities in China from 2003 to 2021, this study employs the Time-Varying Differences-in-Differences (Time-Varying DID) approach to systematically examine the impact of smart city construction on pollution emissions and its underlying mechanisms. Additionally, the Propensity Score Matching-Differences-in-Differences method is employed for further validation. The research findings indicate that Smart City Construction (SCC) significantly reduces urban Volume of Sewage Discharge (VSD), sulfur dioxide emissions (SO
Language	English
Publishing date	2024-03-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-57138-3
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Article ; Online: Endoscopic application of magnetic compression anastomosis: a review.

Zhang, Guo / Liang, Zheng / Zhao, Guiping / Zhang, Shutian

Journal of gastroenterology and hepatology

2024

Abstract: Magnetic compression anastomosis (MCA) is a new method that provides sutureless passage construction for tubular organs. Due to the high recurrence rate of conventional endoscopic treatment and the high morbidity and mortality of surgical procedures, the ...

Abstract	Magnetic compression anastomosis (MCA) is a new method that provides sutureless passage construction for tubular organs. Due to the high recurrence rate of conventional endoscopic treatment and the high morbidity and mortality of surgical procedures, the MCA technique shows promise. The aim of this review is to comprehensively examine the literature related to the use of MCA in different gastrointestinal diseases over the past few years, categorizing them according to the anastomotic site and describing in detail the various methods of magnet delivery and the clinical outcomes of MCA. MCA is an innovative technique, and its use represents an advancement in the field of minimally invasive interventions. Comparison studies have shown that the anastomosis formed by MCA is comparable to or better than surgical sutures in terms of general appearance and histology. Although most of the current research has involved animal studies or studies with small populations, the safety and feasibility of MCA have been preliminarily demonstrated. Large prospective studies involving populations are still needed to guarantee the security of MCA. For technologies that have been initially used in clinical settings, effective measures should also be implemented to identify, even prevent, complications. Furthermore, specific commercial magnets must be created and optimized in this emerging area.
Language	English
Publishing date	2024-04-18
Publishing country	Australia
Document type	Journal Article ; Review
ZDB-ID	632882-9
ISSN	1440-1746 ; 0815-9319
ISSN (online)	1440-1746
ISSN	0815-9319
DOI	10.1111/jgh.16574
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Zs.A 2180: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: A Single-Cell Landscape of Spermioteleosis in Mice and Pigs.

Liu, Meng-Meng / Fan, Chu-Qi / Zhang, Guo-Liang

Cells

2024 Volume 13, Issue 7

Abstract: 1) Background: Spermatozoa acquired motility and matured in epididymis after production in the testis. However, there is still limited understanding of the specific characteristics of sperm development across different species. In this study, we ... ...

Abstract	(1) Background: Spermatozoa acquired motility and matured in epididymis after production in the testis. However, there is still limited understanding of the specific characteristics of sperm development across different species. In this study, we employed a comprehensive approach to analyze cell compositions in both testicular and epididymal tissues, providing valuable insights into the changes occurring during meiosis and spermiogenesis in mouse and pig models. Additionally, we identified distinct gene expression signatures associated with various spermatogenic cell types. (2) Methods: To investigate the differences in spermatogenesis between mice and pigs, we constructed a single-cell RNA dataset. (3) Results: Our findings revealed notable differences in testicular cell clusters between these two species. Furthermore, distinct gene expression patterns were observed among epithelial cells from different regions of the epididymis. Interestingly, regional gene expression patterns were also identified within principal cell clusters of the mouse epididymis. Moreover, through analysing differentially expressed genes related to the epididymis in both mouse and pig models, we successfully identified potential marker genes associated with sperm development and maturation for each species studied. (4) Conclusions: This research presented a comprehensive single-cell landscape analysis of both testicular and epididymal tissues, shedding light on the intricate processes involved in spermatogenesis and sperm maturation, specifically within mouse and pig models.
MeSH term(s)	Mice ; Male ; Animals ; Swine ; Semen ; Testis/metabolism ; Spermatozoa/metabolism ; Epididymis/metabolism ; Spermatogenesis/genetics
Language	English
Publishing date	2024-03-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2661518-6
ISSN	2073-4409 ; 2073-4409
ISSN (online)	2073-4409
ISSN	2073-4409
DOI	10.3390/cells13070563
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