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  1. Book ; Online ; E-Book: Integrated smart micro-systems towards personalized healthcare

    Song, Yu / Gao, Wei / Zhang, Haixia

    2022  

    Author's details Yu Song, Wei Gao, Haixia Zhang
    Keywords Medical technology ; Microelectronics ; Personalized medicine
    Subject code 610.285
    Language English
    Size 1 online resource (219 pages)
    Publisher Wiley-VCH
    Publishing place Weinheim, Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-527-83348-X ; 3-527-83347-1 ; 3-527-83346-3 ; 9783527349401 ; 978-3-527-83348-1 ; 978-3-527-83347-4 ; 978-3-527-83346-7 ; 3527349405
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Service Innovation Construction of University Library in the Era of Fragmented Reading

    ZHANG Haixia

    Nongye tushu qingbao xuebao, Vol 32, Iss 1, Pp 65-

    2020  Volume 72

    Abstract: Purpose/Significance] With the development of informatization, the prevalence of fragmented reading has brought impact to the development of university libraries. This paper puts forward some suggestions for the construction of libraries in the ... ...

    Abstract [Purpose/Significance] With the development of informatization, the prevalence of fragmented reading has brought impact to the development of university libraries. This paper puts forward some suggestions for the construction of libraries in the fragmented reading environment by analyzing the current situation of fragmented reading in colleges and universities. [Method/Process] This study explores the opportunities and challenges of fragmentation mainly through questionnaires and data analysis. [Results/Conclusions] Although fragmentation has impacted the development of traditional libraries, it brought new opportunities. It not only stimulated the enthusiasm of librarians to learn continuously, but also brought new opportunities to the development of university libraries in the construction of information services.
    Keywords university library|fragmented reading|reader service ; Bibliography. Library science. Information resources ; Z ; Agriculture ; S
    Subject code 027
    Language Chinese
    Publishing date 2020-01-01T00:00:00Z
    Publisher Editorial Department of Journal of Library and Information Science in Agriculture
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: [Characterization of rabbit corneal biomechanical properties after corneal refractive surgery based on rapid loading-unloading uniaxial tensile test].

    Zhang, Di / Zhang, Haixia / Li, Lin

    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi

    2024  Volume 41, Issue 1, Page(s) 136–143

    Abstract: In order to understand how the biomechanical properties of rabbit cornea change over time after corneal ablation, 21 healthy adult rabbits were used in this study, with the left eye as experimental side and the right eye as the control side. Firstly, a ... ...

    Abstract In order to understand how the biomechanical properties of rabbit cornea change over time after corneal ablation, 21 healthy adult rabbits were used in this study, with the left eye as experimental side and the right eye as the control side. Firstly, a lamellar knife was used to remove a portion of the anterior corneal surface tissue (30%~50% of the original corneal thickness) from the left eye of each rabbit, as an animal model simulating corneal refractive surgery. Secondly, postoperative experimental rabbits were kept for one, three, or six months until being euthanized. Strip specimens were produced using their corneas
    MeSH term(s) Animals ; Rabbits ; Cornea/surgery ; Refractive Surgical Procedures ; Biomechanical Phenomena
    Language Chinese
    Publishing date 2024-02-25
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2576847-5
    ISSN 1001-5515
    ISSN 1001-5515
    DOI 10.7507/1001-5515.202306041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6887: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Identification of risk factors and development of a predictive model for chronic kidney disease in patients with obesity: a four-year cohort study.

    Zhang, Haixia / Zhang, Yue / Gao, Wenxing / Mu, Yiming

    Lipids in health and disease

    2024  Volume 23, Issue 1, Page(s) 57

    Abstract: Objective: The sneaky onset and dismal prognosis of chronic kidney disease (CKD) make it an important public health issue. Obesity-related kidney illness has garnered more attention in recent times. Establishing and validating a risk prediction model ... ...

    Abstract Objective: The sneaky onset and dismal prognosis of chronic kidney disease (CKD) make it an important public health issue. Obesity-related kidney illness has garnered more attention in recent times. Establishing and validating a risk prediction model for chronic renal illness in overweight or obese adults was the goal of this investigation.
    Methods: Data from the China Health and Retirement Longitudinal Study were used for analysis. The definition of CKD was reduced renal function (eGFR < 60 mL/min/1.73 m²), while overweight and obesity were characterized through a body mass index exceeding 24 kg/m². The dataset was divided into derivation and validation cohorts using a 7:3 ratio. With respect to the derivation cohort, we constructed a prediction model using LASSO analysis and multivariate logistic regression. The model's performance was evaluated using Hosmer-Lemeshow tests, calibration curves, decision curve analysis, and receiver operating characteristic (ROC) curves. The validation cohort's model was subjected to additional assessment.
    Results: The study was based on survey data from 2011 to 2015 and comprised 3246 individuals who were overweight or obese, with 2274 being part of the derivation cohort and 972 being part of the validation cohort. The research constructed a prediction model that included age, sex, fasting blood glucose, glycated hemoglobin, triglyceride, hypertension, and BMI. The validation cohort's area under the ROC curve was 0.812 (95% CI = 0.763, 0.859) while the derivation cohort's was 0.789 (95% CI = 0.754, 0.831). Hosmer-Lemeshow tests were utilized to evaluate the model's accuracy in the validation and derivation cohorts (P = 0.681 and 0.547, respectively). The calibration curve showed a high level of consistency between the actual observations and the projected outcomes. According to decision curve analysis, the model offered significant net advantages.
    Conclusions: The forecasting model established in this research has predictive value for CKD in patients with overweight or obesity. These findings could help doctors conduct early detection and intervention in clinical practice and further improve patient prognosis.
    MeSH term(s) Adult ; Humans ; Cohort Studies ; Longitudinal Studies ; Overweight ; Predictive Value of Tests ; Risk Factors ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/etiology ; Obesity/complications ; Retrospective Studies
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091381-3
    ISSN 1476-511X ; 1476-511X
    ISSN (online) 1476-511X
    ISSN 1476-511X
    DOI 10.1186/s12944-024-02048-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Design of Branch Definition Algorithm for Top-

    Zhang, Haixia / Peng, Qingxiu

    publication RETRACTED

    Applied bionics and biomechanics

    2022  Volume 2022, Page(s) 3365161

    Abstract: Images are the main way for human beings to obtain and exchange information, and they play a crucial role in the process of human understanding and exploration of the world. Top- ...

    Abstract Images are the main way for human beings to obtain and exchange information, and they play a crucial role in the process of human understanding and exploration of the world. Top-
    Language English
    Publishing date 2022-03-03
    Publishing country Egypt
    Document type Journal Article ; Retracted Publication
    ZDB-ID 2179924-6
    ISSN 1754-2103 ; 1176-2322
    ISSN (online) 1754-2103
    ISSN 1176-2322
    DOI 10.1155/2022/3365161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Peptide-Drug Conjugates: Design, Chemistry, and Drug Delivery System as a Novel Cancer Theranostic.

    Rizvi, Syed Faheem Askari / Zhang, Linjie / Zhang, Haixia / Fang, Quan

    ACS pharmacology & translational science

    2024  Volume 7, Issue 2, Page(s) 309–334

    Abstract: The emergence of peptide-drug conjugates (PDCs) that utilize target-oriented peptide moieties as carriers of cytotoxic payloads, interconnected with various cleavable/noncleavable linkers, resulted in the key-foundation of the new era of targeted ... ...

    Abstract The emergence of peptide-drug conjugates (PDCs) that utilize target-oriented peptide moieties as carriers of cytotoxic payloads, interconnected with various cleavable/noncleavable linkers, resulted in the key-foundation of the new era of targeted therapeutics. They are capable of retaining the integrity of conjugates in the blood circulatory system as well as releasing the drugs at the tumor microenvironment. Other valuable advantages are specificity and selectivity toward targeted-receptors, higher penetration ability, and drug-loading capacity, making them a suitable candidate to play their vital role as promising carrier agents. In this review, we summarized the types of cell-targeting (CTPs) and cell-penetrating peptides (CPPs) that have broad applications in the advancement of targeted drug-delivery systems (DDS). Moreover, the techniques to overcome the limitations of peptide-chemistry for their extensive implementation to construct the PDCs. Besides this, the diversified breakthrough of linker chemistry, and ample knowledge of various cytotoxic payloads used in PDCs in recent years, as well as the mechanism of action of PDCs was critically discussed. The principal aim is to provide scattered and diversified knowledge in one place and to help researchers understand the pinching knots in the science of PDC development, also their progression toward a bright future for PDCs as novel theranostics in clinical practice.
    Language English
    Publishing date 2024-01-24
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2575-9108
    ISSN (online) 2575-9108
    DOI 10.1021/acsptsci.3c00269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The viscoelasticity, anisotropy and location-dependence of mechanical properties of rabbit iris investigated using uniaxial tensile tests.

    Li, Tan / Qin, Xiao / Liu, Zhicheng / Zhang, Haixia / Li, Lin

    Acta of bioengineering and biomechanics

    2024  Volume 25, Issue 2, Page(s) 85–92

    Abstract: Purpose: Abnormal iris mechanical properties have been considered to be an important cause of pupillary-block and angle-closure glaucoma. In this research, viscoelasticity, anisotropy and location-dependence of mechanical properties of rabbit iris were ... ...

    Abstract Purpose: Abnormal iris mechanical properties have been considered to be an important cause of pupillary-block and angle-closure glaucoma. In this research, viscoelasticity, anisotropy and location-dependence of mechanical properties of rabbit iris were investigated using uniaxial tensile test.
    Methods: Iris strips were taken along three directions: inner-circumferential direction (ICD), outer-circumferential direction (OCD) and radial direction (RD), respectively. Quasi-static tensile tests and stress-relaxation tests were applied on the iris strips. Then, the stress-stretch data was fitted with third order Ogden model; the stress-relaxation data was fitted with the third order Prony series model. Through comparing the tangent modulus and relaxation limit of the strips from different directions and locations, the viscoelasticity, anisotropy and location-dependence of mechanical properties of rabbit iris were explored.
    Results: The tangent moduli of iris at the stretch of 1.05 along ICD, OCD, and RD were 3.2 ± 1.4 kPa, 4.2 ± 2.6 kPa, 1.5 ± 0.8 kPa, respectively. Iris strips in ICD and OCD were found to have almost the same stress-relaxation behavior, and both relaxed slower than iris strips in RD.
    Conclusions: The mechanical properties of the iris were typically nonlinear, viscoelastic, anisotropic and location-dependent. The stress growth rate of the circumferential direction iris strip is significantly lower than that of RD and the stress-relaxation rate is significantly higher than that of the RD. That is, the iris is more prone to deformation in RD and the stress-retention ability after deformation in RD is weak, which is consistent with the fact that the iris bombe more likely happens in RD in vivo. The results of this study may also help us to establish a more accurate finite element model to simulate the flow field of humor aqueous and find the key factor of pupillary-block.
    MeSH term(s) Animals ; Rabbits ; Anisotropy ; Iris ; Stress, Mechanical ; Tensile Strength ; Elasticity
    Language English
    Publishing date 2024-01-19
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2559094-7
    ISSN 1509-409X
    ISSN 1509-409X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Case report: Primary sarcoma of the mandible with a novel

    Zhou, Peng / Liu, Wei / Zheng, Jiaoyun / Zhang, Haixia / Luo, Jiadi

    Frontiers in oncology

    2024  Volume 14, Page(s) 1369046

    Abstract: Primary sarcomas of the jaw are very rare tumor with unclear mechanism of tumorigenesis. Identification of genetic alterations contributes to better understanding of tumorigenesis and extension of tumor spectrum, as well as potential therapeutic targets ... ...

    Abstract Primary sarcomas of the jaw are very rare tumor with unclear mechanism of tumorigenesis. Identification of genetic alterations contributes to better understanding of tumorigenesis and extension of tumor spectrum, as well as potential therapeutic targets application. Herein, we firstly report a case of primary sarcoma in the mandible with novel
    Language English
    Publishing date 2024-03-28
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2024.1369046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: A survey of bloodborne occupational exposure protection behavior among qualified Chinese midwives: A cross-sectional study.

    Zhang, Yanhua / Zhang, Haixia / Li, Li / Li, Jing

    Heliyon

    2023  Volume 9, Issue 11, Page(s) e21288

    Abstract: Background: Bloodborne occupational exposure is a major public health concern of the China Health Commission, especially among midwives who are at high risk among healthcare workers. Knowledge of occupational exposure and appropriate protective ... ...

    Abstract Background: Bloodborne occupational exposure is a major public health concern of the China Health Commission, especially among midwives who are at high risk among healthcare workers. Knowledge of occupational exposure and appropriate protective behaviors play important roles in reducing occupational exposure. The purpose of this study was to understand the knowledge and level of protection against bloodborne occupational exposure among midwives in China.
    Methods: This was a multi-center, cross-sectional study. Midwives from hospitals that are members of Infectious Disease Nursing Committee of Chinese Nursing Association were selected as survey participants from February 2019 to February 2022 using a judged sampling method. Data were collected by using a self-developed questionnaire for Chinese midwives to report their current knowledge and behavior related to bloodborne occupational exposure protection.
    Results: A total of 2850 questionnaires were distributed and 2742 valid questionnaires were obtained, resulting in an effective rate of 96.21 %. Midwives scored 2742 (6.495 ± 1.529) points for their knowledge about bloodborne occupational exposure protection, with the level and type of hospital being independent factors affecting the midwives' knowledge of bloodborne occupational exposure protection (χ2 = 27.284, P = 0.038; χ2 = 28.374, P = 0.000). Of the midwives, 1460 were qualified for bloodborne occupational exposure protection behavior, with a qualified rate of 53.25 %. Working years (χ2 = 9.372, P = 0.002) and working hours (χ2 = 13.933, P = 0.000) were also the independent factors for bloodborne occupational exposure protective behavior in midwives.
    Conclusion: Chinese midwives possess relatively good knowledge of bloodborne exposure protection against bloodborne infectious diseases, but their behavioral level is not optimistic. Improvements to both knowledge and behavioral level of bloodborne occupational exposure protection are necessary.
    Language English
    Publishing date 2023-11-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e21288
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: An Inverse Method to Determine Mechanical Parameters of Porcine Vitreous Bodies Based on the Indentation Test.

    Zu, Haicheng / Zhang, Kunya / Zhang, Haixia / Qian, Xiuqing

    Bioengineering (Basel, Switzerland)

    2023  Volume 10, Issue 6

    Abstract: The vitreous body keeps the lens and retina in place and protects these tissues from physical insults. Existing studies have reported that the mechanical properties of vitreous body varied after liquefaction, suggesting mechanical properties could be ... ...

    Abstract The vitreous body keeps the lens and retina in place and protects these tissues from physical insults. Existing studies have reported that the mechanical properties of vitreous body varied after liquefaction, suggesting mechanical properties could be effective parameters to identify vitreous liquefaction process. Thus, in this work, we aimed to propose a method to determine the mechanical properties of vitreous bodies. Fresh porcine eyes were divided into three groups, including the untreated group, the 24 h liquefaction group and the 48 h liquefaction group, which was injected collagenase and then kept for 24 h or 48 h. The indentation tests were carried out on the vitreous body in its natural location while the posterior segment of the eye was fixed in the container. A finite element model of a specimen undertaking indentation was constructed to simulate the indentation test with surface tension of vitreous body considered. Using the inverse method, the mechanical parameters of the vitreous body and the surface tension coefficient were determined. For the same parameter, values were highest in the untreated group, followed by the 24 h liquefaction group and the lowest in the 48 h liquefaction group. For C
    Language English
    Publishing date 2023-05-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering10060646
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