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Article ; Online: Valuing nurses' mental health and enhancing their psychological resilience.

Zhang, Hongxia

The Lancet regional health. Western Pacific

2022 Volume 30, Page(s) 100643

Language	English
Publishing date	2022-11-11
Publishing country	England
Document type	Journal Article
ISSN	2666-6065
ISSN (online)	2666-6065
DOI	10.1016/j.lanwpc.2022.100643
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Article ; Online: A rare hemodialysis vascular access complication-Internal jugular vein reflux.

Xiong, Xiaowei / Zhang, Hongxia

Journal of clinical ultrasound : JCU

2024

Abstract: Hemodialysis (HD) arteriovenous fistulas commonly present with late vascular access complications, but are rarely in association with internal jugular vein (IJV) reflux. We reported two patients who had severe and mild IJV reflux, respectively. Case 1 ... ...

Abstract	Hemodialysis (HD) arteriovenous fistulas commonly present with late vascular access complications, but are rarely in association with internal jugular vein (IJV) reflux. We reported two patients who had severe and mild IJV reflux, respectively. Case 1 was a 48-year-old male with end-stage renal disease (ESRD) who had been treated with HD for 5 years. He presented with persistent headaches, nausea, and vomiting. Combined with all the examinations, it was revealed severe IJV reflux, brachiocephalic vein stenosis, high-flow vascular access, and IJV valve dysfunction. Case 2 was a 59-year-old female with ESRD who had constructed an AVF for 4 months and had been on HD for only 1 day. She presented with dizziness and nausea after the first hemodialysis and duplex ultrasonography showed slightly continuous IJV reflux, high-flow vascular access, and IJV valve dysfunction. Furthermore, we reviewed 16 case reports to identify the characteristics of IJV reflux in HD patients. IJV reflux in HD patients may be caused by high-flow access, central venous stenosis or occlusion, and valve dysfunction. Severe IJV reflux can develop neurological symptoms secondary to intracranial venous reflux in this article. Etiological treatment is helpful for these patients, but there is a risk of recurrence.
Language	English
Publishing date	2024-01-03
Publishing country	United States
Document type	Case Reports
ZDB-ID	189393-2
ISSN	1097-0096 ; 0091-2751
ISSN (online)	1097-0096
ISSN	0091-2751
DOI	10.1002/jcu.23633
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Zs.A 1186: Show issues

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Article ; Online: Lévy noise influences basin stability in a delayed vegetation-water dynamical system.

Zhang, Hongxia / Song, Yi

Chaos (Woodbury, N.Y.)

2023 Volume 33, Issue 4

Abstract: The stochastic stability for the irregular attraction basin in a time-delayed vegetation-water ecosystem disturbed by Lévy noise is explored. We first discuss that average delay time does not change the attractors of the deterministic model but affects ... ...

Abstract	The stochastic stability for the irregular attraction basin in a time-delayed vegetation-water ecosystem disturbed by Lévy noise is explored. We first discuss that average delay time does not change the attractors of the deterministic model but affects the corresponding attraction basins, and we present the generation of Lévy noise. Then, we investigate the influence of stochastic parameters and delay time on the ecosystem by two statistical indicators, the first escape probability (FEP) and the mean first exit time (MFET). The numerical algorithm for calculating the FEP and the MFET in the irregular attraction basin is implemented, which is effectively verified by Monte Carlo simulations. Furthermore, the metastable basin is defined by the FEP and the MFET and confirms the consistency of the two indicators reflecting results. The result shows that the stochastic stability parameter, especially the noise intensity, decreases the basin stability of the vegetation biomass. In this environment, the time delay effect can validly alleviate its instability.
Language	English
Publishing date	2023-04-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	1472677-4
ISSN	1089-7682 ; 1054-1500
ISSN (online)	1089-7682
ISSN	1054-1500
DOI	10.1063/5.0137230
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Article: Increased Extracellular Water in Normal-Appearing White Matter in Patients with Cerebral Small Vessel Disease.

Man, Shuqian / Chen, Songkuan / Xu, Zhihua / Zhang, Hongxia / Cao, Zhenyu

Journal of integrative neuroscience

2024 Volume 23, Issue 2, Page(s) 46

Abstract: Background: Microcirculatory variations have been observed in the normal-appearing white matter (NAWM) of individuals affected by cerebral small vessel disease (CSVD). These variations collectively possess the potential to trigger neuroinflammation and ... ...

Abstract	Background: Microcirculatory variations have been observed in the normal-appearing white matter (NAWM) of individuals affected by cerebral small vessel disease (CSVD). These variations collectively possess the potential to trigger neuroinflammation and edema, ultimately leading to an elevation in extracellular fluid (ECF). Nevertheless, the specific alterations in ECF within the NAWM of CSVD patients have remained inadequately understood. Methods: We reviewed the clinical and imaging characteristics of a cohort comprising 129 patients diagnosed with CSVD to investigate alterations in the ECF within NAWM. The severity of CSVD was assessed by total CSVD magnetic resonance (MR) score according to the four imaging markers, namely perivascular space, lacunar infarction, white matter hyperintensities and cerebral microbleed. ECF was evaluated by the parameter free water (FW), ranging from 0 to 1 generated from diffusion tensor imaging. Results: Significant differences in NAWM FW were observed in relation to the total CSVD MR score ( Conclusions: ECF in NAWM is increased in CSVD patients, even during the early course of CSVD.
MeSH term(s)	Humans ; White Matter/diagnostic imaging ; White Matter/pathology ; Diffusion Tensor Imaging ; Microcirculation ; Magnetic Resonance Imaging/methods ; Cerebral Small Vessel Diseases/diagnostic imaging
Language	English
Publishing date	2024-02-28
Publishing country	Singapore
Document type	Review ; Journal Article
ZDB-ID	2136427-8
ISSN	0219-6352
ISSN	0219-6352
DOI	10.31083/j.jin2302046
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Article ; Online: The insights into the phage communities of fermented foods in the age of viral metagenomics.

Zhang, Huadong / Zhang, Hongxia / Du, Hai / Yu, Xiaowei / Xu, Yan

Critical reviews in food science and nutrition

2024 , Page(s) 1–13

Abstract: Phages play a critical role in the assembly and regulation of fermented food microbiome through lysis and lysogenic lifestyle, which in turn affects the yield and quality of fermented foods. Therefore, it is important to investigate and characterize the ... ...

Abstract	Phages play a critical role in the assembly and regulation of fermented food microbiome through lysis and lysogenic lifestyle, which in turn affects the yield and quality of fermented foods. Therefore, it is important to investigate and characterize the diversity and function of phages under complex microbial communities and nutrient substrate conditions to provide novel insights into the regulation of traditional spontaneous fermentation. Viral metagenomics has gradually garnered increasing attention in fermented food research to elucidate phage functions and characterize the interactions between phages and the microbial community. Advances in this technology have uncovered a wide range of phages associated with the production of traditional fermented foods and beverages. This paper reviews the common methods of viral metagenomics applied in fermented food research, and summarizes the ecological functions of phages in traditional fermented foods. In the future, combining viral metagenomics with culturable methods and metagenomics will broaden the scope of research on fermented food systems, revealing the complex role of phages and intricate phage-bacterium interactions.
Language	English
Publishing date	2024-01-12
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1037504-1
ISSN	1549-7852 ; 1040-8398
ISSN (online)	1549-7852
ISSN	1040-8398
DOI	10.1080/10408398.2023.2299323
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Zs.A 1459: Show issues

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Article: The value of lung ultrasound score in neonatal respiratory distress syndrome: a prospective diagnostic cohort study.

Huang, Chunyan / Zhang, Shaoqin / Ha, Xiaoming / Cui, Yanfang / Zhang, Hongxia

Frontiers in medicine

2024 Volume 11, Page(s) 1357944

Abstract: Rationale: The accurate diagnosis of critically ill patients with respiratory failure can be achieved through lung ultrasound (LUS) score. Considering its characteristics, it is speculated that this technique might also be useful for patients with ... ...

Abstract	Rationale: The accurate diagnosis of critically ill patients with respiratory failure can be achieved through lung ultrasound (LUS) score. Considering its characteristics, it is speculated that this technique might also be useful for patients with neonatal respiratory distress syndrome (NRDS). Thus, there is a need for precise imaging tools to monitor such patients. Objectives: This double-blind randomized cohort study aims to investigate the impact of LUS and related scores on the severity of NRDS patients. Methods: This study was conducted as a prospective double-blind randomized study. Bivariate correlation analysis was conducted to investigate the relationship between LUS score and Oxygenation Index (OI), Respiratory Index (RI), and Sequential Organ Failure Assessment (SOFA) score. Spearman's correlation coefficient was used to generate correlation heat maps, elucidating the associations between LUS and respective parameters in different cohorts. Receiver Operating Characteristic (ROC) curves were employed to calculate the predictive values, sensitivity, and specificity of different scores in determining the severity of NRDS. Results: This study ultimately included 134 patients admitted to the intensive care unit (ICU) between December 2020 and June 2022. Among these patients, 72 were included in the NRDS cohort, while 62 were included in the Non-NRDS (N-NRDS) cohort. There were significant differences in the mean LUS scores between NRDS and N-NRDS patients ( Conclusion: Our double-blind randomized cohort study demonstrates that LUS, RI, OI, and SOFA scores can effectively monitor the lung ventilation and function in NRDS. Moreover, these parameters and their combination have significant predictive value in evaluating the severity and prognosis of NRDS patients. Therefore, these results provide crucial insights for future research endeavors.
Language	English
Publishing date	2024-02-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2775999-4
ISSN	2296-858X
ISSN	2296-858X
DOI	10.3389/fmed.2024.1357944
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Article ; Online: Analysis of complete hydatidiform mole in one twin using traditional and molecular techniques.

Wang, Lijing / Hu, Haiyan / Wang, Xue / Xu, Fengsen / Zhang, Hongxia

Journal of clinical ultrasound : JCU

2024

Abstract: A pregnant woman with hydatidiform mole in one twin was misdiagnosed as one of the twins with embryonic arrest. She chose to terminate the pregnancy and developed distant lung metastasis. After chemotherapy, she eventually recovered. This article ... ...

Abstract	A pregnant woman with hydatidiform mole in one twin was misdiagnosed as one of the twins with embryonic arrest. She chose to terminate the pregnancy and developed distant lung metastasis. After chemotherapy, she eventually recovered. This article systematically analyzes the diagnosis and treatment of hydatidiform mole in one twin to increase the awareness and reduce misdiagnosis of the disease.
Language	English
Publishing date	2024-01-24
Publishing country	United States
Document type	Case Reports
ZDB-ID	189393-2
ISSN	1097-0096 ; 0091-2751
ISSN (online)	1097-0096
ISSN	0091-2751
DOI	10.1002/jcu.23637
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Article ; Online: Effect of butylphthalide combined with idebenone on vascular dementia: A retrospective observational analysis.

Zhang, Hongxia / Wu, Huijun / Qi, Xiaoyuan / Wu, Fan / Zhang, Danxue

Medicine

2024 Volume 103, Issue 9, Page(s) e37495

Abstract: To explore the efficacy and safety of butylphthalide combined with idebenone in the treatment of vascular dementia. The clinical data of 126 patients with vascular dementia who were admitted to our hospital between March 2021 and February 2023 were ... ...

Abstract	To explore the efficacy and safety of butylphthalide combined with idebenone in the treatment of vascular dementia. The clinical data of 126 patients with vascular dementia who were admitted to our hospital between March 2021 and February 2023 were retrospectively reviewed. Among them, 62 patients received butylphthalide alone (single group) and 64 patients received butylphthalide combined with idebenone (combined group). Cognitive function scores, serum inflammatory factor levels, oxidative stress index levels, and incidence of adverse reactions were compared between the 2 groups before and after treatment. After treatment, the Hasegawa Dementia Scale, Mini Mental State Examination Scale, and activities of daily living scores in both groups were higher than before treatment, and the scores in the combined group were higher than before treatment (P < .05). After treatment, the levels of serum C-reactive protein, tumor necrosis factor-α, and interleukin 6 in both groups were lower than those before treatment, and those in the combined group were lower than those in the simple group (P < .05). After treatment, the levels of serum glutathione peroxidase and superoxide dismutase in the 2 groups were higher than those before treatment, and the level of malondialdehyde was lower than that before treatment. The levels of serum glutathione peroxidase and superoxide dismutase in the combined group were higher than those in the simple group, and the level of malondialdehyde was lower than that in the simple group (P < .05). There was no significant difference in the incidence of adverse reactions between the combined group (6.25%) and the simple group (3.23%) (P > .05). Compared with butylphthalide alone, intervention of butylphthalide combined with idebenone on vascular dementia can effectively reduce the degree of inflammatory and oxidative stress reactions, improve cognitive function, and promote the ability to perform activities of daily living in a safe manner.
MeSH term(s)	Humans ; Dementia, Vascular/drug therapy ; Retrospective Studies ; Activities of Daily Living ; Glutathione Peroxidase ; Malondialdehyde ; Superoxide Dismutase ; Benzofurans ; Ubiquinone/analogs & derivatives
Chemical Substances	idebenone (HB6PN45W4J) ; 3-n-butylphthalide (822Q956KGM) ; Glutathione Peroxidase (EC 1.11.1.9) ; Malondialdehyde (4Y8F71G49Q) ; Superoxide Dismutase (EC 1.15.1.1) ; Benzofurans ; Ubiquinone (1339-63-5)
Language	English
Publishing date	2024-02-28
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000037495
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Article ; Online: Interspecific grafting promotes poplar growth and drought resistance via regulating phytohormone signaling and secondary metabolic pathways.

Han, Qingquan / Yang, Le / Xia, Linchao / Zhang, Hongxia / Zhang, Sheng

Plant physiology and biochemistry : PPB

2024 Volume 210, Page(s) 108594

Abstract: Populus cathayana (C) grafted onto P. deltoides (D) (C/D) can promote growth better than self-grafting (C/C and D/D). However, the mechanisms underlying growth and resistance to drought stress are not clear. In this study, we performed physiological and ... ...

Abstract	Populus cathayana (C) grafted onto P. deltoides (D) (C/D) can promote growth better than self-grafting (C/C and D/D). However, the mechanisms underlying growth and resistance to drought stress are not clear. In this study, we performed physiological and RNA-seq analysis on the different grafted combinations. It was found that C/D plants exhibited higher growth, net photosynthetic rate, IAA content and intrinsic water use efficiency (WUE
Language	English
Publishing date	2024-04-02
Publishing country	France
Document type	Journal Article
ZDB-ID	742978-2
ISSN	1873-2690 ; 0981-9428
ISSN (online)	1873-2690
ISSN	0981-9428
DOI	10.1016/j.plaphy.2024.108594
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Article ; Online: Cerebellum and Aging: Update and Challenges.

McElroy, Christopher L / Wang, Brian / Zhang, Hongxia / Jin, Kunlin

Aging and disease

2024

Abstract: The cerebellum plays a vital role in the aging process. With the aging of the cerebellum, there is a decline in balance and motor function, particularly fine motor skills, and an increased risk of falling. However, in recent years, numerous studies have ... ...

Abstract	The cerebellum plays a vital role in the aging process. With the aging of the cerebellum, there is a decline in balance and motor function, particularly fine motor skills, and an increased risk of falling. However, in recent years, numerous studies have revealed that the cerebellum has several roles beyond balance and fine motor skills, such as cognitive function and memory. It also plays a role in many neurodegenerative diseases. Interestingly, the cerebellum ages more rapidly than other brain regions, including the hippocampus. With increasing studies reporting that the cerebellum has a more prominent and interconnected role in the brain, it is essential to understand why aging affects it more, leading to solutions to help curb the accelerated decline. Here, we summarize the cerebellum's function and look at how it ages at the cellular, molecular, and functional levels. Additionally, we explore the the effects of alcoholism on the aging cerebellum as well as the role of the cerebellum in diseases such as Alzheimer's, Parkinson's, and Multiple Sclerosis.
Language	English
Publishing date	2024-03-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2625789-0
ISSN	2152-5250 ; 2152-5250
ISSN (online)	2152-5250
ISSN	2152-5250
DOI	10.14336/AD.2024.0220
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