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  1. Article: [Research advances on the role of nuclear factor-erythroid 2-related factor 2 in wound healing].

    Guo, J / Zhang, J X

    Zhonghua shao shang yu chuang mian xiu fu za zhi

    2023  Volume 39, Issue 1, Page(s) 91–95

    Abstract: Wound healing is one of the common pathophysiological processes in the body. How to improve the condition of wound healing to promote rapid wound healing has always been a hotspot in research. Oxidative stress is one of the important factors affecting ... ...

    Abstract Wound healing is one of the common pathophysiological processes in the body. How to improve the condition of wound healing to promote rapid wound healing has always been a hotspot in research. Oxidative stress is one of the important factors affecting wound healing. Nuclear factor-erythroid 2-related factor 2 (Nrf2) is a classic antioxidant stress factor as well as a factor with great potential in facilitating wound healing. The activation of Nrf2 can regulate the downstream antioxidant stress elements and play roles of anti-apoptosis and cell homeostasis maintaining, which improves wound healing environment and promotes wound repair. This paper summarized the common agonists and inhibitors of Nrf2 and reviewed the roles of Nrf2 in promoting skin wound healing including diabetic ulcers, radiation injury, and ischemia-reperfusion injury, etc.
    MeSH term(s) Antioxidants/pharmacology ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress ; Wound Healing/physiology
    Chemical Substances Antioxidants ; NF-E2-Related Factor 2 ; NFE2L2 protein, human
    Language Chinese
    Publishing date 2023-02-03
    Publishing country China
    Document type English Abstract ; Journal Article ; Review
    ISSN 2097-1109
    ISSN 2097-1109
    DOI 10.3760/cma.j.cn501225-20220531-00209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A 2

    Zhang, J X / Wang, C M

    Journal of physics. Condensed matter : an Institute of Physics journal

    2023  Volume 35, Issue 12

    Abstract: ... A ... ...

    Abstract A 2
    Language English
    Publishing date 2023-01-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472968-4
    ISSN 1361-648X ; 0953-8984
    ISSN (online) 1361-648X
    ISSN 0953-8984
    DOI 10.1088/1361-648X/acb47a
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  3. Article: [Research progress on rodent animal models of heart failure with preserved ejection fraction].

    Xia, C L / Zhang, J X

    Zhonghua xin xue guan bing za zhi

    2022  Volume 50, Issue 7, Page(s) 646–652

    MeSH term(s) Animals ; Heart Failure ; Models, Animal ; Rodentia ; Stroke Volume ; Ventricular Function, Left
    Language Chinese
    Publishing date 2022-07-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 603425-1
    ISSN 0253-3758
    ISSN 0253-3758
    DOI 10.3760/cma.j.cn112148-20210804-00667
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  4. Article: [Effect of a novel pH-responsive tertiary amine monomer dodecylmethylaminoethyl methacrylate modified resin adhesive on biofilm formation of

    Zhang, J X / Li, B L / Zhou, X D / Cheng, L

    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology

    2024  Volume 59, Issue 1, Page(s) 45–53

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Streptococcus mutans ; Lacticaseibacillus casei ; Methacrylates/pharmacology ; Methacrylates/metabolism ; Dental Cements ; Dental Caries/prevention & control ; Dental Caries/microbiology ; Polysaccharides/metabolism ; Polysaccharides/pharmacology ; Amines/metabolism ; Amines/pharmacology ; Biofilms ; Hydrogen-Ion Concentration
    Chemical Substances Methacrylates ; Dental Cements ; Polysaccharides ; Amines
    Language Chinese
    Publishing date 2024-01-01
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1027950-7
    ISSN 1002-0098
    ISSN 1002-0098
    DOI 10.3760/cma.j.cn112144-20231018-00206
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  5. Article: [Based on CT radiomics model for predicting the response to first-line chemotherapy of diffuse large B-cell lymphoma].

    Yin, M X / Su, Q N / Song, X / Zhang, J X

    Zhonghua zhong liu za zhi [Chinese journal of oncology

    2023  Volume 45, Issue 5, Page(s) 438–444

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Retrospective Studies ; Lymphoma, Large B-Cell, Diffuse/diagnostic imaging ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Algorithms ; Niacinamide ; Tomography, X-Ray Computed
    Chemical Substances Niacinamide (25X51I8RD4)
    Language Chinese
    Publishing date 2023-05-15
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 603424-x
    ISSN 0253-3766
    ISSN 0253-3766
    DOI 10.3760/cma.j.cn112152-20220628-00459
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  6. Article: [Role of inducible costimulatory molecules (ICOS) and related cytokines in immune regulation of

    Yang, C C / Zhang, J X / Wei, Q / Jiang, T

    Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control

    2022  Volume 33, Issue 6, Page(s) 575–582

    Abstract: Objective: To investigate the roles of inducible costimulatory molecules (ICOS) and related cytokines in the immune regulation of : Methods: Eighty BALB/c mice (weight 18-22 g) were divided into the control and infection groups, of 40 animals in each ...

    Abstract Objective: To investigate the roles of inducible costimulatory molecules (ICOS) and related cytokines in the immune regulation of
    Methods: Eighty BALB/c mice (weight 18-22 g) were divided into the control and infection groups, of 40 animals in each group.
    Results: There were no significant differences in serum ALT (
    Conclusions: High ICOS expression is present in the liver of mice with
    MeSH term(s) Alanine Transaminase ; Animals ; Aspartate Aminotransferases ; Cytokines ; Echinococcosis ; Echinococcus granulosus ; Inducible T-Cell Co-Stimulator Protein ; Liver ; Mice ; Mice, Inbred BALB C
    Chemical Substances Cytokines ; Icos protein, mouse ; Inducible T-Cell Co-Stimulator Protein ; Aspartate Aminotransferases (EC 2.6.1.1) ; Alanine Transaminase (EC 2.6.1.2)
    Language Chinese
    Publishing date 2022-02-06
    Publishing country China
    Document type Journal Article
    ISSN 1005-6661
    ISSN 1005-6661
    DOI 10.16250/j.32.1374.2021034
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  7. Article: [Research progress on the immunological pathogenesis of occupational medicamentosa-like dermatitis due to trichloroethylene].

    Wang, Y C / Zhang, J X / Zhu, Q X

    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

    2021  Volume 39, Issue 8, Page(s) 628–631

    Abstract: Occupational exposure to trichloroethylene can induce a series of immune diseases which include systemic rash, multiple system and organ damage, which are defined as occupational medicamentosa-like dermatitis due to trichloroethylene (OMLDT) . This ... ...

    Abstract Occupational exposure to trichloroethylene can induce a series of immune diseases which include systemic rash, multiple system and organ damage, which are defined as occupational medicamentosa-like dermatitis due to trichloroethylene (OMLDT) . This article reviews the research progress of the role of T cell immunity, humoral immunity and complement system in the immunological pathogenesis of OMLDT to provide theoretical basis for the diagnosis and treatment of OMLDT.
    MeSH term(s) Complement System Proteins ; Dermatitis, Occupational/etiology ; Humans ; Occupational Exposure ; Trichloroethylene/toxicity
    Chemical Substances Trichloroethylene (290YE8AR51) ; Complement System Proteins (9007-36-7)
    Language Chinese
    Publishing date 2021-09-06
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 1050900-8
    ISSN 1001-9391
    ISSN 1001-9391
    DOI 10.3760/cma.j.cn121094-20200727-00427
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  8. Article: [The role of epigenetic effect in the trichloroethylene toxicity].

    Huang, H / Zhang, J X / Zhu, Q X

    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

    2021  Volume 39, Issue 5, Page(s) 385–389

    Abstract: Trichloroethylene (TCE) is a commonly used organic solvent in industry and it was classified as a Group I carcinogen by IARC, with immunotoxicity, hepatotoxicity, kidney toxicity and neurotoxicity. Increasing evidence suggests that TCE-induced autoimmune ...

    Abstract Trichloroethylene (TCE) is a commonly used organic solvent in industry and it was classified as a Group I carcinogen by IARC, with immunotoxicity, hepatotoxicity, kidney toxicity and neurotoxicity. Increasing evidence suggests that TCE-induced autoimmune diseases and cancer are involved in epigenetic modifications. This paper summarized the mechanism of DNA methylation, histone modification and microRNA in toxicity of TCE according to the newly published articles, so as to provide new ideas for further revealing the mechanism of TCE exposure affecting health.
    MeSH term(s) DNA Methylation ; Epigenesis, Genetic ; Humans ; Neoplasms ; Solvents ; Trichloroethylene/toxicity
    Chemical Substances Solvents ; Trichloroethylene (290YE8AR51)
    Language Chinese
    Publishing date 2021-05-24
    Publishing country China
    Document type Journal Article
    ZDB-ID 1050900-8
    ISSN 1001-9391
    ISSN 1001-9391
    DOI 10.3760/cma.j.cn121094-20200602-00313
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  9. Article: [Research progress in biomarkers for diagnosis of glaucoma].

    Zhang, J X / Zhang, S Q / Yuan, H P

    Zhonghua yan ke za zhi] Chinese journal of ophthalmology

    2021  Volume 57, Issue 9, Page(s) 707–711

    Abstract: Glaucoma is a serious irreversible blinding disease. The pathogenesis is still unknown, and the diagnosis and treatment effect is not good. An effective early diagnosis method is urgently needed. In recent years, a number of glaucoma-related biomarkers ... ...

    Abstract Glaucoma is a serious irreversible blinding disease. The pathogenesis is still unknown, and the diagnosis and treatment effect is not good. An effective early diagnosis method is urgently needed. In recent years, a number of glaucoma-related biomarkers have been discovered. In order to promote clinical application of these biomarkers, a series of studies are actively carried out to clarify specificity and sensitivity of these molecules, to verify the criteria by clinical randomized controlled trials, and to provide large sample data by multi-center clinical trials. However, the samples of these biomarkers are provided by patients who have been diagnosed with glaucoma by clinical examinations. The differences may represent the molecular features of middle-stage and advanced glaucoma. Whether they are helpful for early diagnosis and the exploration of pathological mechanisms should be further investigated. This article describes the potential molecular targets that can help in diagnosis of glaucoma from the aspects of DNA, RNA and protein, and discusses further research pathways and clinical application prospects. It is hoped to explore the effective molecular marker for early diagnosis of glaucoma.
    MeSH term(s) Biomarkers ; Early Diagnosis ; Glaucoma/diagnosis ; Humans
    Chemical Substances Biomarkers
    Language Chinese
    Publishing date 2021-12-05
    Publishing country China
    Document type Journal Article
    ZDB-ID 604574-1
    ISSN 0412-4081
    ISSN 0412-4081
    DOI 10.3760/cma.j.cn112142-20210331-00151
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  10. Article: [Research progress in the relationship between cellular senescence and chronic obstructive pulmonary disease].

    Wang, B N / Zhang, J X / Bai, C

    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

    2021  Volume 44, Issue 1, Page(s) 59–63

    MeSH term(s) Cellular Senescence ; Humans ; Pulmonary Disease, Chronic Obstructive
    Language Chinese
    Publishing date 2021-01-07
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 1027965-9
    ISSN 1001-0939
    ISSN 1001-0939
    DOI 10.3760/cma.j.cn112147-20200203-00047
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