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Article ; Online: Preservation versus non-preservation of left colic artery during laparoscopic radical operation for sigmoid colon cancer.

Zhang, Jun-Wei / Sun, Yi

2023 Volume 46, Issue 11, Page(s) 5014–5015

MeSH term(s)	Humans ; Sigmoid Neoplasms/surgery ; Mesenteric Artery, Inferior/surgery ; Lymph Node Excision ; Lymph Nodes/surgery ; Laparoscopy ; Rectal Neoplasms/surgery
Language	English
Publishing date	2023-09-22
Publishing country	Netherlands
Document type	Letter
ZDB-ID	1068461-x
ISSN	0219-3108 ; 1015-9584
ISSN (online)	0219-3108
ISSN	1015-9584
DOI	10.1016/j.asjsur.2023.06.046
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Article ; Online: Distal pancreatectomy with and without routine Intraperitoneal drainage.

Zhang, Jun-Wei / Yang, Xiaobo

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.

2022 Volume 22, Issue 6, Page(s) 826–827

MeSH term(s)	Drainage ; Humans ; Pancreatectomy ; Pancreatic Fistula ; Postoperative Complications ; Retrospective Studies
Language	English
Publishing date	2022-06-20
Publishing country	Switzerland
Document type	Letter
ZDB-ID	2056680-3
ISSN	1424-3911 ; 1424-3903
ISSN (online)	1424-3911
ISSN	1424-3903
DOI	10.1016/j.pan.2022.06.256
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Article ; Online: Letter to the editor: Cautious use of multistate modeling in prognosis analysis of HCC.

Jiang, Shi-Tao / Zhang, Jun-Wei / Lu, Xin / Xu, Yi-Yao

Hepatology (Baltimore, Md.)

2022 Volume 76, Issue 5, Page(s) E97

MeSH term(s)	Humans ; Carcinoma, Hepatocellular ; Liver Neoplasms ; Prognosis
Language	English
Publishing date	2022-04-27
Publishing country	United States
Document type	Letter ; Research Support, Non-U.S. Gov't ; Comment
ZDB-ID	604603-4
ISSN	1527-3350 ; 0270-9139
ISSN (online)	1527-3350
ISSN	0270-9139
DOI	10.1002/hep.32533
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Article ; Online: Letter to the editor: Discussion on application scenario of cell-free DNA fragmentomics in primary liver cancer.

Jiang, Shi-Tao / Zhang, Jun-Wei / Lu, Xin / Xu, Yi-Yao

Hepatology (Baltimore, Md.)

2022 Volume 76, Issue 2, Page(s) E44

MeSH term(s)	Cell-Free Nucleic Acids ; Humans ; Liver Neoplasms/genetics
Chemical Substances	Cell-Free Nucleic Acids
Language	English
Publishing date	2022-04-06
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	604603-4
ISSN	1527-3350 ; 0270-9139
ISSN (online)	1527-3350
ISSN	0270-9139
DOI	10.1002/hep.32477
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Article: Primary gastrinoma of the gallbladder: a case report and review of the literature.

Liu, Yao-Ge / Jiang, Shi-Tao / Zhou, Yang / Zhang, Jun-Wei / Sang, Xin-Ting / Zhang, Lei / Lu, Xin / Xu, Yi-Yao

Frontiers in oncology

2024 Volume 13, Page(s) 1279766

Abstract: Background: Primary gallbladder gastrinoma is an exceptionally uncommon tumor and is a rare form of neuroendocrine neoplasm. Until now, no cases of primary gallbladder gastrinoma and rare cases of primary gastrinoma from the biliary system have been ... ...

Abstract	Background: Primary gallbladder gastrinoma is an exceptionally uncommon tumor and is a rare form of neuroendocrine neoplasm. Until now, no cases of primary gallbladder gastrinoma and rare cases of primary gastrinoma from the biliary system have been reported. Case presentation: We report a case of a 50-year-old woman with watery diarrhea who intermittently received proton pump inhibitors (PPIs) as treatment. A serum gastrin level of 711 pg/ml was recorded after the withdrawal of PPI over 1 week. Enhanced computed tomography (CT) imaging and octreotide imaging uncovered a solitary tumor at the hepatic hilar region. During the laparoscopic surgery, it was determined that the tumor had its origin in the wall of the gallbladder neck, prompting the implementation of a laparoscopic cholecystectomy. Histological analysis revealed a primary neuroendocrine tumor from the neck of the gallbladder. The patient's symptoms disappeared after the surgery with a follow-up of 6 months. Conclusions: This case confirmed that primary gallbladder gastrinoma represents a distinct nosological entity. Immunohistochemical analysis plays a pivotal role in the diagnostic process. Given the limited understanding of primary gallbladder gastrinoma, our objective is to offer novel insights into this rare disease by delivering distinctive information and highlighting the therapeutic significance of surgical intervention.
Language	English
Publishing date	2024-01-31
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2023.1279766
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Article ; Online: Development and validation of web-based nomograms for predicting survival status in patients with intrahepatic cholangiocarcinoma depending on the surgical status: a SEER database analysis.

Liu, Yao-Ge / Jiang, Shi-Tao / Zhang, Jun-Wei / Zhang, Lei / Zhao, Hai-Tao / Sang, Xin-Ting / Lu, Xin / Xu, Yi-Yao

Scientific reports

2024 Volume 14, Issue 1, Page(s) 1568

Abstract: This study aimed to develop and validate prognostic nomograms that can estimate the probability of 1-, 3- and 5-year overall survival (OS) as well as cancer-specific survival (CSS) for Intrahepatic cholangiocarcinoma (ICCA) patients. Clinical data of ... ...

Abstract	This study aimed to develop and validate prognostic nomograms that can estimate the probability of 1-, 3- and 5-year overall survival (OS) as well as cancer-specific survival (CSS) for Intrahepatic cholangiocarcinoma (ICCA) patients. Clinical data of 1446 patients diagnosed with ICCA between 2010 and 2017 from the Surveillance, Epidemiology, and End Results (SEER) database were analyzed. In both the OS and the CSS group, the training cohort and validation cohort were divided into a 7:3 ratio. Age, sex, AJCC T stage, AJCC N stage, AJCC M stage, surgical status, and tumor grade were selected as independent prognostic risk factors to build the nomograms. To compare the efficacy of predicting 1-, 3-, and 5-year OS and CSS rates of the nomogram with the 8th edition of the American Joint Committee on Cancer (AJCC) staging system, we evaluated the Harrell's index of concordance (C-index), area under the receiver operating characteristic curve (AUC) and decision curve analysis (DCA) in both cohorts. The results showed the nomogram for 1-, 3-, and 5-year OS and CSS prediction performed better than the AJCC staging system. In the subgroup analysis for patients could not receive surgery as the primary treatment. We developed two nomograms for predicting the 1-, and 2-year OS and CSS rates following the same analysis procedure. Results indicate that the performance of both nomograms, which contained sex, AJCC T stage, AJCC M stage, chemotherapy, and tumor grade and prognostic factors, was also superior to the AJCC staging system. Meanwhile, four dynamic network-based nomograms were published. The survival analysis showed the survival rate of patients classified as high-risk based on the nomogram score was significantly lower compared to those categorized as low-risk (P < 0.0001). Finally, accurate and convenient nomograms were established to assist clinicians in making more personalized prognosis predictions for ICCA patients.
MeSH term(s)	Humans ; Nomograms ; Cholangiocarcinoma/surgery ; Risk Factors ; Bile Duct Neoplasms/surgery ; Bile Ducts, Intrahepatic ; Internet ; SEER Program ; Prognosis ; Neoplasm Staging
Language	English
Publishing date	2024-01-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-52025-3
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Article ; Online: Clinical response to adding pyrotinib to pembrolizumab and lenvatinib for HER2-positive advanced intrahepatic cholangiocarcinoma: a case report.

Zhang, Jun-Wei / Yang, Xiaobo / Pan, Boju / Xu, Yiyao / Lu, Xin / Zhao, Hai-Tao

World journal of surgical oncology

2023 Volume 21, Issue 1, Page(s) 108

Abstract: Background: Intrahepatic cholangiocarcinoma (ICC) is a highly lethal hepatobiliary cancer, and very few patients can undergo surgery. The prognosis of advanced ICC is poor, especially in patients who progress after first-line chemotherapy, with a median ...

Abstract	Background: Intrahepatic cholangiocarcinoma (ICC) is a highly lethal hepatobiliary cancer, and very few patients can undergo surgery. The prognosis of advanced ICC is poor, especially in patients who progress after first-line chemotherapy, with a median overall survival of less than 10 months. Case presentation: A 64-year-old male was diagnosed with advanced intrahepatic cholangiocarcinoma with ERBB2 (HER2) 3 + amplification determined by tissue-based testing and confirmed by next-generation sequencing. The patient was treated with pyrotinib added to pembrolizumab and lenvatinib after progressing with pyrotinib and tegafur and responded very well with regression of the tumor on imaging as well as normalization of tumor marker levels without serious adverse events. PET-CT after 6 months of treatment showed a partial response. The progression-free survival with second-line treatment was 17 months. For the third line of therapy, lenvatinib and pembrolizumab were used in combination with bevacizumab. Currently, he has had stable disease for approximately 6 months during third-line treatment. Conclusion: Adding pyrotinib to pembrolizumab and lenvatinib may represent a promising strategy for advanced ICC patients who have high levels of HER2.
MeSH term(s)	Male ; Humans ; Middle Aged ; Positron Emission Tomography Computed Tomography ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cholangiocarcinoma/diagnostic imaging ; Cholangiocarcinoma/drug therapy ; Cholangiocarcinoma/pathology ; Bile Ducts, Intrahepatic/pathology ; Bile Duct Neoplasms/diagnostic imaging ; Bile Duct Neoplasms/drug therapy ; Bile Duct Neoplasms/pathology
Chemical Substances	lenvatinib (EE083865G2) ; pyrotinib ; pembrolizumab (DPT0O3T46P)
Language	English
Publishing date	2023-03-27
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2118383-1
ISSN	1477-7819 ; 1477-7819
ISSN (online)	1477-7819
ISSN	1477-7819
DOI	10.1186/s12957-023-02983-1
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Article ; Online: Extracranial metastasis sites correlate to the incidence risk of brain metastasis in stage IV non-small cell lung cancer: a population-based study.

Zhang, XiaoZhi / Gao, HongXiang / Dang, ShengQiang / Dai, Li / Zhang, JunWei

Journal of cancer research and clinical oncology

2023 Volume 149, Issue 9, Page(s) 6293–6301

Abstract: Purpose: The aim of this study was to analyse the correlation of extracranial metastasis sites (ECMs) to the incidence risk of brain metastasis (BMs) in stage IV non-small cell lung cancer (NSCLC).: Methods: 18349 newly diagnosed patients were ... ...

Abstract	Purpose: The aim of this study was to analyse the correlation of extracranial metastasis sites (ECMs) to the incidence risk of brain metastasis (BMs) in stage IV non-small cell lung cancer (NSCLC). Methods: 18349 newly diagnosed patients were retrospectively analysed, and 4919 pairs of cases were matched by propensity score matching in a 1:1 ratio. Alternative factors were analysed by multivariable logistic regression analysis. And the interaction analysis and subgroup analysis were carried out. Results: The incidences of Brain, Lung, Liver, Bone, Multiple and Other metastasis were 26.9%, 20.2%, 4.6%, 19.9%, 16.9% and 38.3%, respectively. Results suggested that Age, Race, Histological type, Grade, T stage, N stage and Organ metastasis site were risk factors (p < 0.05). The interaction analysis suggested interaction effects between the Primary site, T stage, N stage and Organ metastasis site. The subgroup analysis showed that the Organ metastasis site and the risk of BMs were statistically significant except that the Overlapping subgroup (p = 0.267) of the Primary site. And the incidence risk of BMs in Lung metastasis, Liver metastasis and Bone metastasis groups was lower than that in other metastasis group (OR 1, p < 0.05). There was no significant difference between the Multiple metastasis group and the other metastasis group (OR 1.091, p = 0.169). Conclusion: Advanced age, non-Asian/Pacific Islander, non-squamous cell carcinoma, poorly differentiated grade, and higher T/N stage were risk factors for increased BMs in stage IV NSCLC, and the ECMs were associated with the risk of BMs.
MeSH term(s)	Humans ; Carcinoma, Non-Small-Cell Lung/pathology ; Lung Neoplasms/epidemiology ; Lung Neoplasms/pathology ; Incidence ; Retrospective Studies ; Brain Neoplasms/epidemiology ; Brain Neoplasms/secondary
Language	English
Publishing date	2023-02-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	134792-5
ISSN	1432-1335 ; 0171-5216 ; 0084-5353 ; 0943-9382
ISSN (online)	1432-1335
ISSN	0171-5216 ; 0084-5353 ; 0943-9382
DOI	10.1007/s00432-022-04548-3
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Article ; Online: Air in the biliary duct as an indicator of Type V Mirizzi syndrome: a case report.

Zhang, Jun-Wei / Tian, Feng / Li, Bing-Qi / Wang, Yi-Zhi / Guo, Jun-Chao

Translational cancer research

2022 Volume 9, Issue 2, Page(s) 1284–1287

Abstract: Mirizzi syndrome, known as extrinsic bile compression syndrome (EBCS), is difficult to diagnose without surgery. To the best of our knowledge, our case shows that air in the biliary duct may indicate Type V Mirizzi syndrome. A 48-year-old Chinese male, ... ...

Abstract	Mirizzi syndrome, known as extrinsic bile compression syndrome (EBCS), is difficult to diagnose without surgery. To the best of our knowledge, our case shows that air in the biliary duct may indicate Type V Mirizzi syndrome. A 48-year-old Chinese male, complaining of anorexia with weight loss and jaundice, showed decreased bilirubin for two months after being diagnosed with gallbladder stones. Upon re-examination of the CT, evidence of air in the biliary duct was discovered. Type V EBCS was finally diagnosed during surgery. The patient underwent cholecystectomy, cholecystocolic fistula excision, and Roux-en-Y choledochojejunostomy. The postoperative course was uneventful. Mirizzi's syndrome is a condition which is difficult to diagnose and treat. Air in the biliary duct can be a sign of Type V Mirizzi syndrome, which aids in diagnosis of Type V EBCS before surgery. Cholecystectomy, fistula excision and biliary-enteric anastomosis with Roux-en-Y loop appear to be the most appropriate surgical interventions for the condition.
Language	English
Publishing date	2022-01-15
Publishing country	China
Document type	Case Reports
ZDB-ID	2901601-0
ISSN	2219-6803 ; 2218-676X
ISSN (online)	2219-6803
ISSN	2218-676X
DOI	10.21037/tcr.2019.12.25
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Article: Fine-Scaled Selection of Resting and Hunting Habitat by Leopard Cats (

van der Meer, Esther / Dullemont, Hans / Wang, Ching-Hao / Zhang, Jun-Wei / Lin, Jun-Liang / Pei, Kurtis Jai-Chyi / Lai, Yu-Ching

Animals : an open access journal from MDPI

2023 Volume 13, Issue 2

Abstract: Wildlife is increasingly forced to live in close proximity to humans, resulting in human-wildlife conflict and anthropogenic mortality. Carnivores persisting in human-dominated landscapes respond to anthropogenic threats through fine-scaled spatial and ... ...

Abstract	Wildlife is increasingly forced to live in close proximity to humans, resulting in human-wildlife conflict and anthropogenic mortality. Carnivores persisting in human-dominated landscapes respond to anthropogenic threats through fine-scaled spatial and temporal behavioral adjustments. Although crucial for conservation, quantitative information on these adjustments is scarce. Taiwan’s endangered leopard cat occurs in rural human-dominated landscapes with a high anthropogenic mortality risk. To survive, the nocturnal leopard cat needs suitable habitats for foraging and safe refuge for resting during daytime hours when human activity peaks. In this study, we tracked seven VHF-collared leopard cats. To determine habitat selection patterns, we compared land use at nighttime locations and daytime resting sites with random points and fine-scaled vegetation characteristics at daytime resting sites with random points. Leopard cats selected natural habitats for nighttime hunting and avoided manmade and, to a lesser extent, agricultural habitats or used them according to availability. For daytime resting, leopard cats selected natural habitats and, to a lesser extent semi-natural habitats, such as unused land and abandoned orchards. Resting sites were preferentially situated in natural habitats, with little visibility (<2 m), shrubs, reed and stones, away from areas with high levels of human activity. This suggests leopard cats use a proactive strategy to avoid human encounters, which was supported by the reduced temporal overlap with humans and domestic dogs on agricultural land. Resting sites were placed ca. 1 km apart, 12.9 ± 0.3 m (mean ± SE) from the patch’s edges, in patches with a size of 1.21 ± 0.04 ha (mean ± SE). Our results will assist in identifying and preserving suitable resting habitats to support leopard cat conservation.
Language	English
Publishing date	2023-01-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani13020234
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